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脑脊液屏障
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  brain barrier
     The relationship between the change of blood brain barrier ultrastructure and the relative concentration of plasma cAMP on experimental transient cerebral ischemia in rat
     大鼠实验性短暂脑缺血血浆中cAMP相对浓度与血-脑脊液屏障变化的关系
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     Conclusion PROG could markedly lower permeability of blood brain barrier subjected to 2 h MCAO followed by 22 h reperfusion,and this may be a mechanism of PROG alleviating brain oedema during I/R.
     结论  PROG显著降低缺血 2 h再灌注 2 2 h时血 -脑脊液屏障 (BBB)的通透性 ,这可能是其减轻 I/ R时脑水肿的机制之一
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     Conclusions sICAM-1 participates in the pathological process of BM, and contributes to the damage of blood brain barrier and the formation of brain edema.
     结论 sICAM 1参与BM病理过程 ,介导血脑脊液屏障的破坏和脑水肿的形成。
短句来源
     Conclusions Blood brain barrier damage during the earlier period of EAE might play an important role in the pathogenesis of EAE.
     结论 血 -脑脊液屏障的早期损害在 EAE发病过程中具关键作用。
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     Objective To understand the changes and possible mechanism of the blood brain barrier(BBB) permeability induced by tumor necrosis factor(TNF-α) in vitro.
     目的探讨肿瘤坏死因子-α(TNF-α)对体外血脑脊液屏障(BBB)模型通透性的影响及其调控机制。
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  “脑脊液屏障”译为未确定词的双语例句
     Objective To assess the effect of rherythropoietin(rhEPO),on cerebrocelluar apoptosis of neonatal rats with hypoxic ischemic brain damage(HIBD).
     目的 探讨重组人红细胞生成素 (rhEPO)对新生大鼠缺氧缺血性脑损伤 (HIBD)脑细胞凋亡的影响及rhEPO能否通过血脑脊液屏障
短句来源
     Effect of progesterone on the change of blood-brain barrier in rats during focal cerebral ischemia/reperfusion
     孕酮对局灶脑缺血再灌注大鼠血-脑脊液屏障变化的影响
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     The levels of TNFα,IL2 and Ig were recovered after treatments.
     治疗后 TNFα、IL 2和 Ig水平随病情好转、血脑脊液屏障的修复逐渐趋于正常。
短句来源
     Perilymph cerebrospinal fluid barrier in guinea pig cochlea: a high performance liquid chromatographic study
     耳蜗外淋巴液-脑脊液屏障的高效液相色谱研究
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     Conclusions The BBB of brain metastasis opened wider than normal brain tissue during WBRT. The T/N rise during WBRT at 20 Gy indicated a good radiotherapy effect.
     结论在全脑放疗20Gy时,脑转移瘤的血-脑脊液屏障开放程度要高于正常脑组织,T/N值升高,预示放疗效果佳。
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  相似匹配句对
     Observation of Erythropoietin Acrossing Blood - Brain Barrier of Premature Infants
     促红细胞生成素通过早产儿血脑脊液屏障的观察
短句来源
     Isolated blood-cerebrospinal fluid barrier dysfunction: Prevalence and associated diseases
     单独血-脑脊液屏障功能障碍的发生率和相关疾病
短句来源
     Cerebrospinal fluid rhinorrhea
     脑脊液鼻漏
短句来源
     FLUORINE IN CEREBROSPINAL FLUID
     脑脊液中的氟
短句来源
     playing the role of nutritive barrier;
     营养屏障作用 ;
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  brain barrier
The specific function of the immunocompetent cells, which penetrated beyond the blood-brain barrier under physiological and immunopathological conditions of the CNS, and the apoptotic death of the lymphocytes were suggested.
      
Attention was drawn to the importance of the investigation of systemic, as well as regional, immune processes outside the blood-brain barrier.
      
Insulin penetrates into the brain by means of receptor-dependent transport across the blood-brain barrier and participates in the regulation of energy homeostasis and the reproductive and cognitive functions of an organism.
      
PGP is shown to pass through the blood-brain barrier and, therefore, can act not only at the periphery, but can also directly affect the CNS structures responsible for the regulatory effects involved in maintaining GM homeostasis.
      
Current research efforts are directed at developing oral dopamine analogs that exhibit improved bioavailability and do not traverse the blood-brain barrier.
      
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IgG-like immunoreactivities in the central nervous system were detected by immunocytomistry after injection into rat muscles and elsewhere with mouse IgG against swine motoneurons of the spinal cord.IgG-like reactivities were visualized in motoneurons, the ependyma, the hypothalamic paraventricular nucleus,supraoptic nucleus, interneurons of lamina Ⅷ,X in the spinal cord and reticular formation in the brain stem, and perivascular glial cells and/or neurons etc. Three pathways are involved in IgG transport:(1)...

IgG-like immunoreactivities in the central nervous system were detected by immunocytomistry after injection into rat muscles and elsewhere with mouse IgG against swine motoneurons of the spinal cord.IgG-like reactivities were visualized in motoneurons, the ependyma, the hypothalamic paraventricular nucleus,supraoptic nucleus, interneurons of lamina Ⅷ,X in the spinal cord and reticular formation in the brain stem, and perivascular glial cells and/or neurons etc. Three pathways are involved in IgG transport:(1) axonal retrograde and transcytotic transport,(2) transcytosis between blood brain barrier,(3) transcytosis between blood cerebral spinal fluid barrier.

将小鼠抗猪运动神经元单克隆抗体IgG肌肉注射于大鼠,用免疫组织化学方法显示IgG样阳性反应细胞在中枢神经系统中的分布。结果发现阳性反应细胞主要分布于脊髓前角及脑干运动核团,脊髓第Ⅷ、第Ⅹ板层和脑干网状结构的中间神经元、室管膜、下丘脑室旁核和血管及其周围的神经元或胶质细胞等处。分析可能有三种途径参与了外源性IgG的转运,即逆行轴浆运输和跨细胞转运,跨血脑屏障,跨血脑脊液屏障

The effects of radiation on blood-cerebrospinal fluid barrier was studied quantitatively byobserving the change of Methotrexate(MTX)level in cerebrospinal fluid following intraveneous injection ofMTX before,during and after cerebral irradiation. Observation of 17 cases of irradiated brain tumorsshowed that in cases of cerebral tumors with large volume,their blood-cerebrospinal fluid barrier is serious-ly damaged and in cases of small tumors,thier blood cerebrospinal barrier is generally in good condition.Af-ter...

The effects of radiation on blood-cerebrospinal fluid barrier was studied quantitatively byobserving the change of Methotrexate(MTX)level in cerebrospinal fluid following intraveneous injection ofMTX before,during and after cerebral irradiation. Observation of 17 cases of irradiated brain tumorsshowed that in cases of cerebral tumors with large volume,their blood-cerebrospinal fluid barrier is serious-ly damaged and in cases of small tumors,thier blood cerebrospinal barrier is generally in good condition.Af-ter a dose of 20 Gy irradiation,the blood-cerebrospinal fluid barrier would gradually open,Compared withthe pre-radiation data,the permeability of MTX increased by 1 to 3 times.So it is advisable to givechemotherapy after a dose of tumor dose of 20 Gy irradiation.

用氢甲碟呤(MTX)静脉注射观察脑部照射前、中、后,MTX由血管向脑脊液渗透的动态变化作为定量研究照射剂量对血-脑脊液屏障的影响。通过17例脑瘤照射观察,血脑屏障开放者11例,不开放者6例。脑瘤体积大的病人,其血-脑脊液屏障受损明显,而瘤体小的病例,其血-脑脊液屏障基本完好,照射20Gy后,屏障窗孔逐渐开放,与照射前相比,MTX透过性增加1~3倍,所以照射20Gy后,开始给化疗药是最佳时期。

Objective A pilot study of the destructive effects of radiation on the blood brain barrier (BBB) and blood cerebrospinal fluid barrier (BCSFB) were carried out on 29 patients.Methods (1) First BBB with localized and limited brain tumors was examined by 99m Tc GH imaging count/pixel,data was obtained from the unirradiated, irradiated, and tumor areas of before and after radiotherapy of 20~40 Gy respectively. (2) The BCSFB was studied quantitatively by observing the effect of methotrexate (MTX) permeation...

Objective A pilot study of the destructive effects of radiation on the blood brain barrier (BBB) and blood cerebrospinal fluid barrier (BCSFB) were carried out on 29 patients.Methods (1) First BBB with localized and limited brain tumors was examined by 99m Tc GH imaging count/pixel,data was obtained from the unirradiated, irradiated, and tumor areas of before and after radiotherapy of 20~40 Gy respectively. (2) The BCSFB was studied quantitatively by observing the effect of methotrexate (MTX) permeation into the CSF before, during, and after brain irradiated after i.v.injection of MTX.Results (1) the BBB in the unirradiated area outside the radiation portal was not changed, (2) the degree of destructive effect on the BBB in the irradiated normal area and on the BCSFB were directly proportional to radiation doses.Conclusions When the permeation of BBB and BCSFB irradiated, was enhanced the degree of destructive effect were enhanced proportionally with irradiation doses. It was that the BBB irradiated can be recovered at least partially after irradiation of 3 weeks proved. After a dose of 20 Gy irradiation, the BCSFB would gradually open. As compared with the pre radiation data, the permeability of MTX increased by 1 05~1 3 times. So, it was advisable to give chemotherapy after 20 Gy irradiation.

目的 探讨放射线对血脑屏障的影响,以及放疗与化疗的顺序性及交叉接触的最佳时间。方法 采用99m TCGH 显影技术观察不同剂量放射线对血脑组织屏障的影响,采用静脉注射氨甲喋呤(MTX)观察不同剂量放射线对血脑脊液屏障的影响。结果 放射线有降低血脑屏障的作用,20 Gy 射线照射后血脑屏障功能开始下降,两屏障功能下降程度与照射剂量有关。结论 放射线有降低血脑组织屏障和血脑脊液屏障的作用,且与照射剂量有关。照射20 Gy 后开始化疗是最佳时机

 
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