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浸润方式     
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  pattern of invasion
     THE SIGNIFICANCE OF PCNA EXPRESSION IN SQUAMOUS CELL CARCINOMA OF THE TONGUE WITH DIFFERENT PATTERN OF INVASION
     舌癌不同浸润方式PCNA表达的意义
短句来源
     The special marker of lymphatic vessles,LYVE-1, was used to study the relationship between lymphatic vessel parameters(LVD/LVA) and cervical lymph nodes status and other clinicopathologic parameters,such as age, sex, T stage, histological degree of differentiation and pattern of invasion.
     以LYVE-1作为淋巴管内皮标志物,研究舌癌淋巴管生成参数——淋巴管密度(LVD)和淋巴管面积(LVA)与颈淋巴结转移及其他临床病理变量(年龄、性别、T分类、病理分级、浸润方式)之间的关系。
短句来源
     Results PCNA expression in the tumor cells varied from the pattern of invasion.
     结果 PCNA的表达与肿瘤浸润方式有关。
短句来源
     Objective To investigate the clinical significance of PCNA expression in squamous cell carcinoma of the tongue with different pattern of invasion.
     目的 探讨舌癌不同浸润方式PCNA表达的差异及临床意义。
短句来源
     5. The Mann-Whitney U test was employed to examine the association between lymphatic vessel parameters and cervical lymph nodes status and other clinicopathologic parameters,such as age,sex,T classification,histological degree of differentiation and pattern of invasion,using SPSS 10.0 software.
     5.采用SPSS 10.0软件对淋巴管生成参数(LVD、LVA)与淋巴结转移及其它临床病理变量(年龄、性别、T分类、病理分级、浸润方式)之间的关系进行统计学分析。
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  the mode of invasion
     The Histological Research between the Mode of Invasion and Cervical Lymph Node Metastasis in Squamous Cell Carcinoma of the Oral Cavity
     口腔鳞癌浸润方式与颈淋巴结转移关系的组织学研究
短句来源
     Objective:To evaluate the relationship between the mode of invasion and lymph node metastasis in squamous cell carcinoma of the tongue.
     目的 :评价舌鳞癌肿瘤细胞浸润方式与区域淋巴结转移的关系。
短句来源
     Results With regard to the relationship between the mode of invasion and metastasis, the more invasive the tumor tissue was, the more frequent the metastasis formed (P<0.001).
     结果 鳞癌的浸润方式与鳞癌的颈淋 巴结转移明显相关(P<0.001)。
短句来源
  infiltrative type
     Methods:Retrospective analysis of 90 patients with squamous cell carcinoma of tongue was carried out to ascertain the correlation between lymph node metastasis and location of tumor, T stage, differentiation, infiltrative type, peritumoral lymphocyte infiltration, respectively.
     方法:回顾性分析90例舌鳞状细胞癌的发生部位、T分类、分化程度、肿瘤浸润方式及周围淋巴细胞浸润与肿瘤转移的关系。
短句来源
     In infiltrative type, there was no metastasis in type Ⅰ and type Ⅱ, the constitution of lymph node metastasis was 25.00% in type Ⅲ, and 58.62% in type Ⅳ_C ~ Ⅳ_D, respectively.
     浸润方式与淋巴结转移的关系:Ⅰ~Ⅱ型无淋巴结转移,Ⅲ型为25.00%,ⅣC~ⅣD型为58.62%;
短句来源
     Conclusion: The distribution of positive lymph node metastasis for squamous cell carcinoma of tongue is from level Ⅰ to level Ⅳ, and mainly involve the lymph nodes at level Ⅰ~ level Ⅲ. The factors that influence the metastasis of tongue carcinoma are T stage, differentiation degree, and infiltrative type.
     结论:舌鳞状细胞癌的颈淋巴结转移主要累及Ⅰ~Ⅳ颈部平面,以Ⅰ~Ⅲ颈部平面为主,其转移的发生与肿瘤的T分类、分化程度、浸润方式有明显相关性。
短句来源
  invasion pattern
     In contrast, the reduced expression of the LO gene had no relation to histological classification, invasion pattern, tumor size,and number of metastasis lymph nodes(P >0.05).
     该基因的表达与肿瘤组织学分型、浸润方式、肿瘤大小及淋巴结转移个数等无关(P>0.05)。
短句来源
     DMBT1 is expressed in 9.7%(3/31) of tumors with lymph node metastasis,and 76.5%(13/17) of tumors without lymph node metastasis ( P <0.01). The reduced DMBT1 expression has no correlation with histological classification,tumor invasion pattern and tumor size ( P >0.01).
     伴周围淋巴结转移的癌组织的DMBT1表达率 9.7% (3/ 31)均低于不伴周围淋巴结转移的癌组织的表达率76 .5 % (13/ 17) (P <0 .0 1) ,该基因的表达与肿瘤组织学分型、浸润方式及肿瘤大小等无关 (P均 >0 .0 5 )。
短句来源
     The relationship between invasion pattern and extracapsular spread in lymph node metastasis from squamous cell carcinoma of tongue
     舌癌浸润方式与淋巴结包膜外侵犯的关系及临床意义
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      pattern of invasion
    Both by light and transmission electron microscopy, a similar pattern of invasion was observed as earlier found with experimental rat glioma cells in the same system.
          
    In conclusion, the infiltrative pattern of invasion significantly correlated with advanced disease and poor patient outcome.
          
    The pattern of invasion should be commented upon separately in the pathology report.
          
    These findings allow us to conclude that the less differentiated tumors, which are more invasive and with a pattern of invasion in small group of cells, are associated with the overexpression of MMPs.
          
    This pattern of invasion strongly suggests that sporozoites take an exclusively extraintestinal route to reach the target cells.
          
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      the mode of invasion
    We studied the pathological findings in 28 small hepatocellular carcinomas (less than 5 cm in diameter), especially the mode of invasion.
          
    These results suggest that ECD might play a key role in the genesis of histological differentiation, and that the reduction of ECD expression may affect the mode of invasion and metastasis of human gastric cancer cells.
          
    According to a histopathological analysis of the mode of invasion, highly invasive cases showed the increased gelatinolytic activities of MMP-2 as well as MMP-9 in the tissue specimens.
          
    Distinct differences in the mode of invasion and effect on the host cell have been demonstrated by using these systems.
          
      infiltrative type
    Comparison of electron microscopic observation between expansive type and infiltrative type of hepatocellular carcinoma
          
    Methods: Examination of EHCC and infiltrative type of hepatocellular carcinoma (IHCC) (each 20 cases) by electron microscope (EM) to compare their ultrastructure.
          
    Among the clinocopathological parameters of pancreatic cancer, the incidence of expression of this enzyme was significantly higher in infiltrative type cancers than in expansive and localized tumors.
          
    Cholangiocarcinoma of a raised, elevated type, not an infiltrative type, may be accompanied with superficial spread in the continguous mucosa.
          
    The growth pattern of the tumors was divided into 5 groups: 23 were nonencapsulated sclerosing type, 29 encapsulated type without capsule invasion, 48 encapsulated type with capsule invasion, 4 the infiltrative type, and 4 the round type.
          
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      invasion pattern
    The novel host invasion pattern observed may reduce physical damage to the host in the initial phase of endoparasitism, enhancing parasitoid survival.
          
    For nodal metastasis, tumor thickness of 10 mm or more and the type of invasion pattern were statistically significant.
          
    The pathological slides of 61 operated patients were reevaluated for tumor grade, lymphatic-vascular invasion, invasion pattern of tumor margins, perineural invasion and lymphocytic infiltration.
          
    The invasive component resembled mucinous noncystic carcinoma in all but one tumour which showed a ductal invasion pattern.
          
    Histopathologically, the de novo group also had a significantly higher percentage of cases with an infiltrative invasion pattern.
          
    更多          


    135 patients suffering from cancer of stomach were treated by partialor total gastrectomy during the years of 1960-1973. The relationshipbetween the patholgical findings and the prognosis was evaluated. Thesurvival rate of 5 years and 10 years was 19.2% and 12% respectively. It is only fair to recognize that the prognosis turns to the moredependent on the histological picture of the tumor. It was found that the prognosis of differentiated adenocarcinoma was much better than that ofthe undifferentiated ones,...

    135 patients suffering from cancer of stomach were treated by partialor total gastrectomy during the years of 1960-1973. The relationshipbetween the patholgical findings and the prognosis was evaluated. Thesurvival rate of 5 years and 10 years was 19.2% and 12% respectively. It is only fair to recognize that the prognosis turns to the moredependent on the histological picture of the tumor. It was found that the prognosis of differentiated adenocarcinoma was much better than that ofthe undifferentiated ones, meanwhile the poorly differentiated mucinouscarcinoma of signet ring cell type was less malignant as compared with thelatter. With regard to the biological behaviors of the tumor, the differ-entiated adenocarcinoma was characterized by abundance in glandularformation and expanding pattern of the growth. Both the serosa of stamachand the regional lymph node were rarely attacked. The undifferentiatedcarcinoma, in contrast, showed little or no glandular formation. Themalignant cells penetrated deeply and widely, resulting in diffuse involementof the stomach and quite frequently metastasis to the regional lymph node. The degree of lymphocytes and plasmocytes infiltration in the tissuemay be of some significance because, in prognosis, 13 out of 17 patientssurviyed over 10 years had moderate to heavy infiltration of these cellsin the tumors.

    本文报告135例胃癌的病理形态、生物学行为与预后的关系。证明癌瘤的生长浸润方式、浸润深度、间质淋巴—浆细胞反应和胃旁淋巴结有无癌转移与预后的关系极为密切。并证实以分化程度结合形态分型与胃癌生物学行为密切相关,因此也能反映预后。

    Cancer involvement of nipple has been found in 68 cases of 715 female breast carcinomas. The extent of the nipple infiltration was divided into 3 levels. The 10-year survival rate dropped significantly(P<0. 05)with the escalation of infiltration level. The patterns of infiltration was categorized-into intraductal, stromal and intraductal plus stro-mal.It was found that the prognosis of the patients with intraductal infiltration of the nipple was better than those of stromal infiltration. The closer the nipple...

    Cancer involvement of nipple has been found in 68 cases of 715 female breast carcinomas. The extent of the nipple infiltration was divided into 3 levels. The 10-year survival rate dropped significantly(P<0. 05)with the escalation of infiltration level. The patterns of infiltration was categorized-into intraductal, stromal and intraductal plus stro-mal.It was found that the prognosis of the patients with intraductal infiltration of the nipple was better than those of stromal infiltration. The closer the nipple to the tumor mass,the more chance of the nipple being involved and hardly ever the nipple was spared when the tumor mass was located in the central part of the breast. It is in these patients that conservative surgery evidently is contraindicated.

    本文对1980年至1982年期间715例女性乳腺癌进行回顾性研究,病理证实乳头浸润者68例,发生率9.5%.观察研究了乳头浸润方式、浸润水平、肿瘤位置等因素的特征及其与预后的关系.乳头受浸程度分3个水平,随浸润水平的增加,10年生存率下降(P<0.05).乳头浸润方式分3种:导管浸润、间质浸润和混合形式浸润.观察到沿乳导管浸润乳头者预后优于间质浸润者的趋势.肿瘤距乳头越近,乳头受累机会越大,中央部者几无幸免,不宜行保留乳头的缩小手术.

    The expression of CEA in colorectal cancer tissues and the mucosa adjacent and nomal of 60 cases were studied with PAP method,and the longitudinal invading into the subucosa of the large intestine was measure with micrometer.The results showed that CEA positive rate in colorectal cencer tissues was 96.7% which was significantly higher than that in tissues of the mucosa adjacent to the cancer and nomal mucosa(P<0.01).In the 60 cases of colorectal carcinoma,the range of longitudinal invading less than 0.5 cm was...

    The expression of CEA in colorectal cancer tissues and the mucosa adjacent and nomal of 60 cases were studied with PAP method,and the longitudinal invading into the subucosa of the large intestine was measure with micrometer.The results showed that CEA positive rate in colorectal cencer tissues was 96.7% which was significantly higher than that in tissues of the mucosa adjacent to the cancer and nomal mucosa(P<0.01).In the 60 cases of colorectal carcinoma,the range of longitudinal invading less than 0.5 cm was 41%,less than 1 cm was 78%,2 cm or more only 1.7%.The deeper invaded into intestine wall,the farther invaded along the long axial.There were two types of the longitudinal invading direct spread and embolism in lymph tube It is considered that CEA may be used as an immunohistochemical marker in the study of colorectal cancer.The longitudinal invading of colorectal cancer is rarely more than 2 cm which would provide theortical fondation for the surgical removal of the large intestinal cancer.

    应用PAP法对60例大肠癌、癌旁粘膜及正常粘膜进行了癌胚抗原(CEA)的免疫组化检测,对大肠癌沿肠管的纵向浸润范围进行了形态学测量。结果显示,CEA在大肠癌组织阳性率为96.7%,明显高于癌旁粘膜及正常粘膜(P<0.01),低分化腺癌CEA阳性率明显高于乳头状腺癌和腺癌1级。大肠癌CEA阳性程度与沿肠管纵向浸润距离无关。本组病例41%沿肠管纵向浸润距离在瘤体下缘0.5cm内,78%浸润1cm内,仅1.7%浸润达瘤体下缘2cm以上。肿瘤浸润越深,纵向浸润距离越大(P<0.01)。浸润方式主要有直接蔓延和淋巴管栓塞。大肠癌沿肠等纵向浸润距离很少超过2cm,可作为大肠癌手术切除范围的理论依据。

     
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