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   系统性红斑狼疮患者 的翻译结果: 查询用时:0.547秒
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系统性红斑狼疮患者
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  sle patients
     ②IL-10 enhanced Blys mRNA expression in PBMCs in both healthy controls and SLE patients, with the greatest effect at 12 h (0.487±0.058 vs 0.251±0.050,P< 0.001;0.638±0.084 vs 0.392±0.059,P< 0.001).
     ②IL-10显著增强健康对照和系统性红斑狼疮患者外周血单个核细胞Blys mRNA表达,12h作用最强(0.487±0.058 vs 0.251±0.050,P<0.001;0.638±0.084 vs 0.392±0.059,P<0.001)。
短句来源
     ③IL-10 also increased the expression of membrane-bound Blys protein in both healthy controls and SLE patients (FACs, mean fluorescence intensity, 4.53±0.71 vs 3.24±0.57,P< 0.001; 5.79±0.91 vs 4.55±0.83,P< 0.001).
     ③IL-10显著增强健康对照和系统性红斑狼疮患者外周血单个核细胞膜结合型Blys蛋白表达(FACs,4.53±0.71 vs 3.24±0.57,P<0.001;5.79±0.91 vs 4.55±0.83,P<0.001)。
短句来源
     Over-expression of CCR7 by CD8~+ T Cells in the Active SLE Patients
     活动性系统性红斑狼疮患者CD8~+T细胞CCR7异常高表达
短句来源
     The Expression of CD40 and TRAF1 in Peripheral B Lymphocytes of SLE Patients and Their Significance
     系统性红斑狼疮患者外周血B淋巴细胞CD40、TRAF1的表达及意义
短句来源
     Methods CD19+, CD23+/CD19+ and the HLA-DR+/CD19+ in peripheral blood of SLE patients were detected with two-color fluorograph;
     方法应用流式细胞术检测活动期与稳定期系统性红斑狼疮患者外周血中CD19+、CD23+/CD19+及HLA-DR+/CD19+细胞的表达情况;
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  systemic lupus erythemaitosus
     Ocular surface lesions and relative antibodies in systemic lupus erythemaitosus
     系统性红斑狼疮患者眼表损害及相关抗体检测
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  “系统性红斑狼疮患者”译为未确定词的双语例句
     CCR7~+CD8~+CD45RO~+ T Cells induced Differentiation of CD4~+T Cells to Th2 Cells in Active Systemic Lupus Erythematosus
     系统性红斑狼疮患者CCR7~+CD8~+CD45RO~+T细胞诱导CD4~+T细胞向Th2分化
短句来源
     Expression of Caspase-3 and TRAIL Receptors in CD4 and CD8 T Cells from Systemic Lupus Erythematosus Patients
     系统性红斑狼疮患者CD4和CD8T细胞caspase-3及TRAIL受体表达分析
短句来源
     Changes in the Serum levels of IL-1,SIL-2R,IL-6 and IL-8 in Patients with Systemic Lupus Erythematosus and Its Clinic Significance
     系统性红斑狼疮患者血清IL-1,SIL-2R,IL-6,IL-8的变化及临床意义
短句来源
     CD1a.CD68 and HLA-DR Antigens in the Skin of Patients with Systemic Lupus Erythematosus
     系统性红斑狼疮患者CD1a、CD68、HLA-DR等的研究
短句来源
     Analysis of Peripheral Blood CD_4~+CD_(25)~+ T Cells from the Patients with Systemic Lupus Erythematosus
     系统性红斑狼疮患者外周血CD_4~+CD_(25)~+ T细胞亚群的初步研究
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  sle patients
A history of migraine was commoner in SLE patients than in controls [31(34%) vs 15(16%);P>amp;lt;0.05], and the mean age of onset was higher in the SLE group (26.8 vs 17.2 years).
      
Both migraine and non-migrainous headaches in SLE patients often responded to specific SLE treatment.
      
Glucose utilisation was measured by positron emission tomography (PET) in 35 SLE patients to detect signs of CNS involvement.
      
Global glucose utilisation of SLE patients did not differ significantly from that of normal controls, nor were differences found between SLE patients with or without neurological or cognitive abnormalities.
      
Abnormal EEG was found in 19%, and CT revealed cerebral atrophy in 47% of SLE patients.
      
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Thrombomodulin has been confirmed to be able to accelerate the activation of protein C as a thrombin cofactor. This paper reports an assay on protein C in human plasma samples based on the ability of activated protein C to prolong the kaolincephalin activated partial thromboplastin time of normal plasma. Protein C is first separated from its inhibitor by elution of a barium citrate precipitate, and then activated through incubation with thrombin and thrombomodulin. The length of the coagulation time after recalcifieation...

Thrombomodulin has been confirmed to be able to accelerate the activation of protein C as a thrombin cofactor. This paper reports an assay on protein C in human plasma samples based on the ability of activated protein C to prolong the kaolincephalin activated partial thromboplastin time of normal plasma. Protein C is first separated from its inhibitor by elution of a barium citrate precipitate, and then activated through incubation with thrombin and thrombomodulin. The length of the coagulation time after recalcifieation in the assay serves as a measure of the anticoagulant activity of protein C. When the value in pooled normal plasma was expressed in percentage, the value obtained by this method was proved to be 97±35% in 72 normal control, 178±43% in 30 cases of systemic lupus erythematosus and 116±4(?) in 12 cases of cerebral stroke. The value of systemic lupus erythemal (?)sus, was significantly higher than that of the control (P<0.001), but that in the cases of cerebral stroke showed no remarkable difference. The within-coefficient variation was 6.57, and between-coefficient variation was 15.2. This study has proved protein C assay to be a relatively simple, rapid and less factor-affected method and suitable for routine application. The indices of antithrombin-Ⅲ antigen and activity, Ⅷ:Ag, Fbg/FDP and CIC were also determined in the 30 cases of systemic lupus erythematosus. The role of protein C in thrombosis and hemostasis of the systemic lupus erythematosus patients was discussed in the paper.

本文报告采用纯化的人血栓调节蛋白作为人凝血酶活化血浆蛋白C(PC)的辅助因子所建立的一种人血浆PC抗凝活性的检测方法。本法的标准曲线直线性良好,可信性和重复性满意,所测72例健康人正常值为97±35%;系统性红斑狼疮患者为178±43%,与正常对照组有显著性差异(P<0.001);脑血管病患者为115±46%,与正常值无显著性差异。结合AT-Ⅲ抗原和活性,因子ⅦR∶Ag、Fbg/FDP和CIC等指标,对该检测方法的测定结果,以及血浆PC在系统性红斑狼疮患者止凝血机制异常中的意义进行了探讨。

Subpopulations of lymphocytes in lesions and normal regions of skin ofnine Patients with systemic lupus erythematosus were comparatively studied byABC immunohistochemical method with six monoclonal antibodies.The results indicated that the langerhans cells in epidermis of lesions were signifi-cantly decreased than those of normal regions in the same patient(p<0.05).The chief infiltrated cells in dermis of lesions were E6(HLA-DR)~+andMA6B~+ cells and T_H cells in which the number of E6~+ cells in lesions weresignificantly...

Subpopulations of lymphocytes in lesions and normal regions of skin ofnine Patients with systemic lupus erythematosus were comparatively studied byABC immunohistochemical method with six monoclonal antibodies.The results indicated that the langerhans cells in epidermis of lesions were signifi-cantly decreased than those of normal regions in the same patient(p<0.05).The chief infiltrated cells in dermis of lesions were E6(HLA-DR)~+andMA6B~+ cells and T_H cells in which the number of E6~+ cells in lesions weresignificantly higher than those in normal regions(p<0.05),the same wasin epidermis, While the Leu4(pan-T)~+,Leu3a(T_H)~+and the Leu2a~+ (T_s)cells in the epidermis of lesions were only occasionally seen or almost ab-sent.

本文用6种单抗对9例系统性红斑狼疮患者皮损及正常皮肤中的淋巴细胞亚群作了ABC免疫组化比较检测,结果表明病人皮损表皮中的HIT_(6-1)~+(CD_1,Langerhans细胞)明显低于非皮损处同类细胞,而Leu_4~+(全T)、Lcu 3a~+(TH)、Leu 2a~+(Ts)细胞变化不明显。真皮与表皮皮损中的MA_6~+(B)、E_6~+(HLA-DR)及真皮皮损中的Leu 3a~+细胞则比非皮损处同类细胞多,与患者外周血中IgG水平的升高成正相关。

The hypercoagulable indexes in patients with SLE were studied.The resultsshowed that the levels of plasma Ⅷ R:Ag,Fn and PAgT were increased,APTT wasprolonged,and the levels of ATⅢ:Ag,ATⅢ:C and Plg were not changed.In all 3cases with embolie thrombosis,the levels of Fn,PAgT and Ⅷ R:Ag were signifi-cantly higher than the normal limits and peripheral platelet counts were less than80×10~9/L.It was suggested that increased levels of PAgT and plasma Fn and Ⅷ R:Ag were important indexes for the hypercoagulable state...

The hypercoagulable indexes in patients with SLE were studied.The resultsshowed that the levels of plasma Ⅷ R:Ag,Fn and PAgT were increased,APTT wasprolonged,and the levels of ATⅢ:Ag,ATⅢ:C and Plg were not changed.In all 3cases with embolie thrombosis,the levels of Fn,PAgT and Ⅷ R:Ag were signifi-cantly higher than the normal limits and peripheral platelet counts were less than80×10~9/L.It was suggested that increased levels of PAgT and plasma Fn and Ⅷ R:Ag were important indexes for the hypercoagulable state in lupus patients.

系统性红斑狼疮患者易于并发栓塞性血管病变。为探讨其发生机制,本文检测了16例患者的凝血、抗凝及纤溶系统功能的变化。结果表明 SLE 患者与正常对照相比其 PAgT 明显增强(P<0.01);血浆ⅧR:Ag、Fn 浓度显著升高(P<0.01,0.05);APTT 明显延长(P<0.01)。而 ATⅢ:Ag、ATⅢ:C 及 Plg 无明显改变。3例并发血栓栓塞的患者,APTT 皆明显延长,PAgT、ⅧR:Ag 及血浆 Fn 水平都高于正常;而外周血小板计数均严重减少。本研究提示 SLE 患者血小板聚集功能增强、继发性促凝物质(血浆 Fn、ⅧR:Ag)增加而处于一种高凝状态,可能是其易于并发血栓栓塞性疾病的重要原因。

 
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