Conclusion single chain fused antibody binding specially to HSP70 was selected from the phage library,and it lays the foundation for further research about preparation for the soluble antibody and drug target anti-tumor therapy.
The generation of the IL-21 and IL-21 receptor,the biological activities of IL-21,the mechanism of signal transduction and the research development of IL-21 in the anti-tumor therapy are reviewed in this article.
[Objective]To observe the effects of Qizhu decoction(QD) on both proliferation and apoptosis of the gastric gland cancer cell MGC-803 Caspase-3 and telomerase,and investigate the mechanism of the compound prescribe of Chinese herbs in anti-tumor treatment.
Objective: To construct an eukaryotic expression plasmid containing gene coding for the hemagglutinin neuraminidase(HN) of Newcastle disease virus (NDV), and to study its mechanism and value in antitumor therapy.
[Results] Among 25 patients who had response to anti-cancer therapy, 23 patients showed depressive symptoms ameliorated after withdrawal of fluoxetine, and the remission rate of depression was 92.0%. There were 2 recrudescence of depression after withdrawal of fluoxetine and the recurrence rate was 8.7%.
Methods The clinical data of 91 patients with terminal gynecologic cancers, aged 56 (13~83), who were not suitable to specific anti-cancer therapy and died in the hospital with a mean survival time of 27 days (1~240 days) were analyzed retrospectively.
Studies show that MMPs not only facilitate tumor invasion by degradation of ECM, but also play an important role in tumor growth and angiogenesis. Expression of MMPs is strongly associated with poor outcome of malignant tumor. Anti-cancer therapy aiming directly at MMPs receives attention increasingly.
The understanding of relationships between hypo- and hypermethylation in tumor cells is extremely important due to reversibility of DNA methylation and attempts to utilize for anti-tumor therapy the drugs that modify DNA methylation pattern.
Development of tumor growth and response to anti-tumor therapy combined with 5-fluorouracil and cisplatin was monitored by whole-body bioluminescent imaging (BLI).
Out of a total number of 45 patients with Actinomycosis, 43 (93.5%) suffered from BON (58.7%) or IORN (35.6%), while there were only 3 patients (6.7%) without anti-tumor treatment.
We conclude that the human SART3 DNA vaccine can induce antitumor ability against tumor cells expressing human SART3 (LM8-SART3) in vitro/vivo which may provide new possibilities in antitumor therapy.