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血清nse水平
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  serum nse
     There were positive correlations between the serum NSE level and the volume of hemorrhage (r=0.421, P<0.01) and NDS (r=0.415, P<0.01).
     脑出血患者血清NSE水平与出血量及NDS呈正相关(r=0.421,P<0.01;r=0.415,P<0.01);
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     Serum MBP and serum NSE levels were determined by ELISA. Results Serum NSE level in the exposed workers was(8.4±7.7)μg/L,which was higher than that in the controls [(7.8±3.2)μg/L,P<0.05].
     结果接触组和对照组的血清NSE含量分别为(8.4±7.7)、(7.8±3.2)μg/L,接触组的血清NSE水平高于对照组(P<0.05);
短句来源
     Methods Serum NSE and plasma ET-1 levels were dynamically measured with RIA in 32 full ferm neonates with HIE on d1 (24h), d3 and d7 as well as in 30 controls (normal neonates at 24h).
     方法:采用放射免疫分析动态测定32例HIE新生儿生后24h、3d、7d血浆ET-1和血清NSE水平,并以30例正常新生儿(生后24h)为正常对照组。
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     The NSE level of patients with pulmonary carcinoma decreased from 62.6±50.9ng/ml to 19.4±17.6ng/ml after chemotherapy. 11 patients with satisfactory therapeutic effect had different degree of decrease of serum NSE level, the other 2 patients with poor therapeutic effect had increases of serum NSE level.
     肺癌病人治疗后的NSE平均水平从治疗前的62.6土50.9ng/ml降至19.4±17.6ng/ml,11例治疗有效病人血清水平均有不同程度下降,2例治疗无效者,血清NSE水平增高。
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     There were markedly positive correlation between CSF and serum NSE(y=0.883x+3.21, r = 0.401 , P <0.05).
     Ⅱ型患者组CSF和血清NSE水平的变化呈明显正相关 (y =0 .883x +3.2 1 ,r=0 .4 0 1 ,P <0 .0 5 )。
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  “血清nse水平”译为未确定词的双语例句
     Results: NSE of the serious asphyxia of newborn were (18.51±2.12)ng/ml,higher than that of normal team(2.05±1.01)ng/ml,and mild asphyxia group(6.13±1.34)ng/ml (P<0.05~0.01);
     结果 重度窒息组的血清NSE水平为 (18.5 1± 2 .12 )ng/ml,高于正常组 (2 .0 5± 1.0 1)ng/ml和轻度窒息组 (6 .13± 1.34)ng/ml,差异有显著性 (P <0 .0 5或 0 .0 1) ;
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     Results NSE levels in serum of patients with major(a), minor(b) head injuries and control individuals(c) were (25 78 ± 10 80)ng/ml, (19 58 ± 8 91)ng/ml and (9 51 ± 2 79)ng/ml respectively, differences of which were significant (P a-b <0 05, P a-c <0 01, P b-c <0 01).
     结果 ⑴重型 (a)、轻型 (b)颅脑损伤患者与对照组(c)的血清NSE水平分别为 ( 2 5 8± 10 8)ng/ml、( 19 6± 8 9)ng/ml和 ( 9 5± 2 8)ng/ml ,存在显著性差异 (Pa -b<0 0 5 ,Pa -c<0 0 1,Pb -c<0 0 1) ;
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     Results The NSE levels in the epilepsy group were significantly increased as compared with the normal controls(t=4.3,2.57 P<0.01,0.05).
     结果癫患者发作48h内及2~4d血清NSE水平与对照组比较有显著性差异(t=4.31,2.57;P<0.01,0.05)。
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     Results The serum level of NSE in ICH group increased within 48 hours, peaked at 3~5 d, obviously higher at 6~9 d and at 10~14 d compared with the control group (P<0.01~0.001).
     结果脑出血组患者在发病48h内血清NSE水平即明显升高,3~5d达到峰值,6~9d和10~14d时仍明显高于正常对照组(P<0.01~0.001);
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     ⑤The sNSE level was associated with the prognosis of the patients with cerebral infarction.
     ⑤血清NSE水平与脑梗死患者的预后相关 ,NSE高的患者 ,其 2周时的预后较差。
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  相似匹配句对
     Changes of serum neuron-specific enolase level in newborns with hypoxic-ischemic encephalopathy
     新生儿缺氧缺血性脑病血清NSE水平的变化
短句来源
     Changes of NSE levels in serum and CSF were similar.
     NSE血清及脑脊液水平变化具有一致性;
短句来源
     Methods:We investigated the levels of NSE in serum by using ELISA.
     方法 :应用ELISA法测定血清NSE水平
短句来源
     Significance of Changes of Serum NSE and CEA Levels in Patients with Pneumonia and Malignant Tumors
     恶性肿瘤患者血清NSE、CEA水平变化及意义
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     Observation of level of bone gla protein in serum
     血清骨钙素水平的观察
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  serum nse
Serum NSE seems to correlate with disease activity as well as Rodnan skin score.
      
The serum NSE value, suggesting to be a neurogenic origin before the histological examination in the present case, is considered to be a valuable marker substance for screening and therapeutic monitoring of neurogenic tumors.
      
Increased serum NSE levels were found in only 5 of 32 patients, there was no correlation between NSE and CT concentrations.
      
Serum NSE and NO levels were lower in CsA-treated animals compared to controls.
      
Ectopic hormone production and a high level of serum NSE (neuron specific enolase), as revealed by biochemical and radioimmunoassay, suggested that this tumor was derived from the cells of the APUD (amine precursor and dehydroxylation) series.
      
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The serum neuron specific enolase (NSE), lipid-pound sialic add (LSA) and carcinoembryonic antigen (CEA) levels were measured in 58 normal controls, 17 patients with benign pulmonary diseases (BPD), 16 patients with small cell lung cancer (SCLQ and 29 patients with non-SCLC. The results showed that serum NSE level was markedly elevated in patients with SCLC compared to non-SCLC and BPD. NSE levels at diagnosis tended to correlate with the initial tumor burden as evidenced by increasing mean NSE value be ing...

The serum neuron specific enolase (NSE), lipid-pound sialic add (LSA) and carcinoembryonic antigen (CEA) levels were measured in 58 normal controls, 17 patients with benign pulmonary diseases (BPD), 16 patients with small cell lung cancer (SCLQ and 29 patients with non-SCLC. The results showed that serum NSE level was markedly elevated in patients with SCLC compared to non-SCLC and BPD. NSE levels at diagnosis tended to correlate with the initial tumor burden as evidenced by increasing mean NSE value be ing associated with increasing number of metastatic sites. Thirteen out of sixteen SCLC patients had NSE level raised but only six had LSA raised (sensitivity 37.5%) and three CEA raised (sensitivity 18.8%). Our study indicated that NSE was more helpful than LSA, CEA for diagnosis and differential diagnosis of SCLC and evaluating status of the disease. The incidence of at least 1 elevated marker increased from 81.3% using NSE alone to 93.8% using NSE, LSA and CEA together.

采用BAS-ELISA法测定了58例正常对照(NC)、17例肺良性疾患(BPD)、16例小细胞肺癌(SCLC)和29例非小细胞肺癌(NSCLC)患者血清神经元特异性烯醇化酶(NSE)水平,并和脂质结合唾液酸(LSA)、癌胚抗原(CEA)作对比研究。结果表明SCLC患者血清NSE水平明显升高,其升高程度与肿瘤负荷有关,随着肿瘤转移数的增加而增加,诊断阳性率达81.3%(13/16),显著高于NSCLC(6.9%)和BPD组(5.9%),特异性93%,诊断准确率为88.9%;而血清LSA、CEA阳性率分别仅为37.5%(6/16)和18.8(3/16)。可见,NSE在SCLC诊断、鉴别诊断和病情判断方面具有更重要的价值。三者联合检测可使阳性率由单测NSE的81.3%上升到93.8%。

An ELISA for neuron-specific enolase (NSE) was developed with 2 NSE-McAbs prepared in our lalyoratory and labeled with HRP. The standard curve was linear and the sensitivity cut-off was 5 ̄50μg/L. Serum levels of NSE was detected in 23 patients with small cell lung cancer (SCLC) , 32 with non small cell lung cancer(NSCLC) ,22 with other pulmonary disease(BPD) and 36 normal controls(NC). The positivity for NSE was 82. 6% in SCLC (50% in stage Ⅰ and Ⅱ ,85. 7% in stage Ⅲ and 91. 7% in stage Ⅳ),and 3. 1%,4. 5% in...

An ELISA for neuron-specific enolase (NSE) was developed with 2 NSE-McAbs prepared in our lalyoratory and labeled with HRP. The standard curve was linear and the sensitivity cut-off was 5 ̄50μg/L. Serum levels of NSE was detected in 23 patients with small cell lung cancer (SCLC) , 32 with non small cell lung cancer(NSCLC) ,22 with other pulmonary disease(BPD) and 36 normal controls(NC). The positivity for NSE was 82. 6% in SCLC (50% in stage Ⅰ and Ⅱ ,85. 7% in stage Ⅲ and 91. 7% in stage Ⅳ),and 3. 1%,4. 5% in NSCLC and BPD,respectively. The serum levels of NSE were significantly higher in SCLC than in NSCLC and BPD(P<0. 01) ,and in stage Ⅲ and Ⅳ of SCLC than in stage Ⅰ and Ⅱ(P<0. 01). NSE concentrations in partial and complete remission group of 23 patients with SCLC after treatment were significantly lower than those of progression group and non-responsive group. It is concluded that two-site sandwich ELISA with NSE-McAb is highly-sensitive ,specific and easy to perform for the diagnosis of SCLC and also has implication in clinical staging and follow-up of the patients.

在自制的8株烯醇化酶(NSE)McAb中,经方阵排列滴定筛选出无交叉反应且效价较高的2株McAb,用辣根过氧化物酶(HRP)为标记物,建立了NSE-McAb双位点夹心ELISA。经直线回归方程、取代试验、阻断试验检验,该标准曲线近似直线关系,可测定标本中NSE的范围为5~50μg/L。对23例小细胞肺癌(SCLC)(Ⅰ和Ⅱ期4例、Ⅲ期7例、Ⅳ期12例).32例非小细胞肺癌(NSCLC),22例肺良性疾病(BPD)和36例健康体检者血清NSE进行了测定,SCLC的阳性率为82.6%(19/23),其中Ⅰ和Ⅱ期为50%(2/4);Ⅲ期为85.7%(6/7),Ⅳ期为91.7%(11/12);NSCLC的阳性率为3.1%(1/32),BPD阳性率为4.5%(1/22)。SCLC的显著高于NSCLC和BPD(P<0.01);SCLC的Ⅳ和Ⅲ期显著高于Ⅰ和Ⅱ期(P<0.01)。23例SCLC经综合治疗后,完全缓解组和部份缓解组血清NSE水平非常显著低于进展组和无改变组(P<0.01)。本文研究结果证明,NSEMcAb双位点夹心ELISA具有灵敏、特异和简便快速的特点,对SCLC的血清学诊断有较高的灵敏度和特异...

在自制的8株烯醇化酶(NSE)McAb中,经方阵排列滴定筛选出无交叉反应且效价较高的2株McAb,用辣根过氧化物酶(HRP)为标记物,建立了NSE-McAb双位点夹心ELISA。经直线回归方程、取代试验、阻断试验检验,该标准曲线近似直线关系,可测定标本中NSE的范围为5~50μg/L。对23例小细胞肺癌(SCLC)(Ⅰ和Ⅱ期4例、Ⅲ期7例、Ⅳ期12例).32例非小细胞肺癌(NSCLC),22例肺良性疾病(BPD)和36例健康体检者血清NSE进行了测定,SCLC的阳性率为82.6%(19/23),其中Ⅰ和Ⅱ期为50%(2/4);Ⅲ期为85.7%(6/7),Ⅳ期为91.7%(11/12);NSCLC的阳性率为3.1%(1/32),BPD阳性率为4.5%(1/22)。SCLC的显著高于NSCLC和BPD(P<0.01);SCLC的Ⅳ和Ⅲ期显著高于Ⅰ和Ⅱ期(P<0.01)。23例SCLC经综合治疗后,完全缓解组和部份缓解组血清NSE水平非常显著低于进展组和无改变组(P<0.01)。本文研究结果证明,NSEMcAb双位点夹心ELISA具有灵敏、特异和简便快速的特点,对SCLC的血清学诊断有较高的灵敏度和特异性,对SC?

The fragements of serum cytokeratin 19 subunit, referred to as CYFRA21-1 were determined using immunoradiometric assay in 133 patients with lung cancer.CYFRA21-1 was significantly higher in lung cancer patients than that of benign pulmonary disease and healthy adults(P<0.001 ).Compared to serum NSE, CYFRA21-1 was more frequently elevated in patients with non-small cell cancer(NSCLC)(Sensitivity:52.8% ),especially squamous cell carcinoma(SQC)(72.1%),than in that with small cell lung cancer(SCLC)(27.3%,P<0.01,P<0.001).In...

The fragements of serum cytokeratin 19 subunit, referred to as CYFRA21-1 were determined using immunoradiometric assay in 133 patients with lung cancer.CYFRA21-1 was significantly higher in lung cancer patients than that of benign pulmonary disease and healthy adults(P<0.001 ).Compared to serum NSE, CYFRA21-1 was more frequently elevated in patients with non-small cell cancer(NSCLC)(Sensitivity:52.8% ),especially squamous cell carcinoma(SQC)(72.1%),than in that with small cell lung cancer(SCLC)(27.3%,P<0.01,P<0.001).In NSCLC, elevated CYFRA21-1 was measured in 35.3% for stageⅠ,55.6%for stageⅡ,63.6% for stage Ⅲ and 73.3% for stage Ⅲ diseases.Elevated NSE was dominant in SCLC with a sensitivity of 59.1%.The sensitivty of all lung cancer case was soared to 61.7% or even higher by combining CYFRA21-1 and NSE.The decline of CYFRA21-1was observed when remission of the tumor became clinically evident.CYFRA21-1seemed to be of clinical interest for NSCLC,particularly so for SQC.

CYFRA21-1是细胞角蛋白19的片段(CK19)。免疫放射法(IRMA)测定133例肺癌患者血清中CYFRA21-1水平,与血清神经元特异性烯醇化酶(NSE)作比较,初步观察了5例非小细胞肺癌患者血清CYFRA21-1在治疗过程中的动态变化。结果表明肺癌患者血清CYFRA21-1水平明显高于肺良性疾患组(P<0.001)和正常对照组(P<0.001);在肺癌患者,血清CYFRA21-1水平升高主要出现在非小细胞肺癌组,尤其是鳞癌组,阳性诊断率分别为52.8%和72.1%,明显高于小细胞肺癌组(27.3%)(P<0.01,P<0.001),在非小细胞肺癌组,血清CYFRA21-1与肿瘤临床分期相关。其阳性诊断率1期为35.3%,Ⅰ期为55.6%,Ⅱ期为63.6%,Ⅳ期为73.3%;血清NSE水平的升高以小细胞肺癌为主,阳性率为59.1%,高于非小细胞肺癌组(21.3%,P<0.001),鳞癌组(27.9%,P<0.001)。联合检测血清CYFRA21-1和NSE可将整体肺癌的阳性诊断率提高至61.7%。对血清CYFRA21-1的动态监测显示肿瘤进展时其水平持续升高。病人预后较差,水平的下降提示疾...

CYFRA21-1是细胞角蛋白19的片段(CK19)。免疫放射法(IRMA)测定133例肺癌患者血清中CYFRA21-1水平,与血清神经元特异性烯醇化酶(NSE)作比较,初步观察了5例非小细胞肺癌患者血清CYFRA21-1在治疗过程中的动态变化。结果表明肺癌患者血清CYFRA21-1水平明显高于肺良性疾患组(P<0.001)和正常对照组(P<0.001);在肺癌患者,血清CYFRA21-1水平升高主要出现在非小细胞肺癌组,尤其是鳞癌组,阳性诊断率分别为52.8%和72.1%,明显高于小细胞肺癌组(27.3%)(P<0.01,P<0.001),在非小细胞肺癌组,血清CYFRA21-1与肿瘤临床分期相关。其阳性诊断率1期为35.3%,Ⅰ期为55.6%,Ⅱ期为63.6%,Ⅳ期为73.3%;血清NSE水平的升高以小细胞肺癌为主,阳性率为59.1%,高于非小细胞肺癌组(21.3%,P<0.001),鳞癌组(27.9%,P<0.001)。联合检测血清CYFRA21-1和NSE可将整体肺癌的阳性诊断率提高至61.7%。对血清CYFRA21-1的动态监测显示肿瘤进展时其水平持续升高。病人预后较差,水平的下降提示疾病缓解。检?

 
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