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膀胱肿瘤细胞的
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  bladder cancer cells
     Conclusion Combination of hTERT promoter and mad1 gene could inhibit the proliferation of bladder cancer cells, which may provide a new idea for gene therapy of bladder carcinoma.
     结论hTERT启动子联合mad1基因能够抑制膀胱肿瘤细胞的增殖能力,可望为膀胱癌基因治疗提供新思路。
短句来源
     Results:TRIO amplification was strongly associated with rapid proliferation of bladder cancer cells(P<0.0001).
     结果TRIO基因扩增与膀胱肿瘤细胞的快速生长相关(P<0.0001)。
短句来源
     Objective: To study peripheral blood monocyte (PBMC) proliferation stimulated by recombinant human IFN-α-2b BCG and lethal effect of bacilli Calmette-Guérin activated killer cell(BAK) on bladder cancer cells.
     目的:研究重组hIFN-α-2b-卡介苗(hIFN-α-2b-BCG)对人外周血单个核细胞(peripheralbloodmonocytes,PBMC)活化增殖,以及BCG激活杀伤细胞(bacilliCalmette-Guérinactivatedkillercell,BAK细胞)对膀胱肿瘤细胞的杀伤效应。
短句来源
     Conclusions Malignant proliferation of bladder cancer cells can be inhibited by exogenous p16 gene transfection via different molecular pathway.
     结论 外源p16 基因导入可通过不同的分子机制抑制膀胱肿瘤细胞的恶性增殖和促进细胞的分化。
短句来源
     Objective:TRIO gene located to human chromosome bands 5p encodes a protein with a putative role in cell-cycle regulation. This study aims to find out whether the amplification and expression of TRIO is correlated to rapid proliferation of bladder cancer cells.
     目的TRIO基因位于染色体5p扩增区、编码1种在细胞周期调节中起主导作用的蛋白,本研究旨在了解TRIO的扩增和表达是否与膀胱肿瘤细胞的快速增殖有关。
短句来源
  “膀胱肿瘤细胞的”译为未确定词的双语例句
     coli BL21/ pGEX-Ag85B/IL-2、Top10/ pTHio-Ag85B/IL-2 and DH5α/ pBV-Ag85B/IL-2 were successfully constructed .
     3.Ag85B/IL-2融合蛋白在体外对膀胱肿瘤细胞的免疫抑制效应⑴ 利用CTLL-2株,MTT法检测Ag85B/IL-2融合蛋白的IL-2比活性,结果为2500 u/mg。
短句来源
     Methods The cell proliferation, cell cycle progression, cell ultrastructure alterations, mRNA and protein expression of hTERT and TGF-β1 were detected by cell counting, transmission electron microscopy (TEM), flow cytometry (FCM), reverse transcription polymerase chain reaction (RT-PCR) and immunocytochemistry after T24 and EJ cells were respectively treated with hTERT promoter and mad1 gene plasmids.
     方法采用细胞计数、电子显微镜、流式细胞术、RT-PCR及免疫组化等方法,观察hTERT启动子联合mad1基因表达质粒转染T24和EJ细胞后的膀胱肿瘤细胞的增殖能力、生长周期、细胞超微结构的变化以及hTERT和TGF-β1mRNA基因和蛋白表达影响。
短句来源
     Objective To preparare arsenic trioxide-loaded albumin Immuno-nanospheres As_2O_3-(BSA-NS)-BDI-1 targeted with Monoclonal Antibody BDI-1 and test its specific killing effect on bladder tumor cell.
     目的 制备单抗BDI 1导向的三氧化二砷免疫蛋白微球 [As2 O3 (BSA NS) BDI 1]并检测其特异性结合膀胱肿瘤细胞的活性。
短句来源
     3H-TDR incorporation showed the specific killing activity of As 2O 3-(HAS-NS)-BDI-1 on bladder tumor cells.
     3 H TDR掺入法进一步验证了其特异性杀伤膀胱肿瘤细胞的活性。
短句来源
     OBJECTIVE:To study the results of different expression leves of HER2 of bladder carcinoma cell line which was treated by inhibitor of protein tyrosine kinase (PD168393).
     目的:探讨酪氨酸激酶抑制剂PD168393对HER2不同表达水平的膀胱肿瘤细胞的作用。
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  相似匹配句对
     Objective To understand biological characteristics of transferable bladder tumor cells.
     目的 了解可移植膀胱肿瘤细胞的生物学特性。
短句来源
     Biological Characteristics of Transferable Bladder Tumor Cells and Preliminary Established Animal Model
     可移植膀胱肿瘤细胞的生物学特性及相关动物模型的初步建立
短句来源
     Effects of Electromagnetic Pulses on Tumor Cells
     电磁脉冲对肿瘤细胞的影响
短句来源
     E-cadherin and bladder tumor
     E-钙粘素和膀胱肿瘤
短句来源
     Bladder-preserving strategy for bladder tumor
     膀胱肿瘤保留膀胱的策略
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  bladder cancer cells
Conclusion: The constructed chimeric antibody was expressed successfully in eukaryotic cells, and the chimeric antibody had desired affinity against human bladder cancer cells.
      
Effect of photodynamic therapy with BPD-MA on the proliferation and apoptosis of human bladder cancer cells
      
OBJECTIVE This study was conducted to explore the effect of Rg3 on inhibition of proliferation and induction of apoptosis in bladder cancer cells.
      
On Day 21 the tumors were resected and examined pathologically to see the immune response.Results: The observation of morphology of MBT-2 cells in vitro and MTT assay indicated that Allicin has apparent direct cytotoxicity to bladder cancer cells.
      
To study the effects of arsenic trioxide (As2O3) on the in vitro growth of human bladder cancer cells and the mechanisms.
      
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With Northern blot and radioimmunoassay, we first have found the expression of TGF*********a mRNA in bladder carcinoma cells.In bladder transitional cell carcinoma BIU-87 cells, TPA(12-o-tetradecanoylphorol-13-acetate) can increase the levels of TGF **********a mRNA and TGF *********aa, but decrease the level and affinity of EGF receptor, which is also the receptor of TGF************a.These data suggest that TGF*********a is responsible to the abnormal growth of bladder carcinoma and TGF*********a mRNA can be...

With Northern blot and radioimmunoassay, we first have found the expression of TGF*********a mRNA in bladder carcinoma cells.In bladder transitional cell carcinoma BIU-87 cells, TPA(12-o-tetradecanoylphorol-13-acetate) can increase the levels of TGF **********a mRNA and TGF *********aa, but decrease the level and affinity of EGF receptor, which is also the receptor of TGF************a.These data suggest that TGF*********a is responsible to the abnormal growth of bladder carcinoma and TGF*********a mRNA can be modulatde in a protein kinase Cdependent manner.

应用Northern印渍杂交和放射免疫分析技术证明了膀胱癌组织和细胞中TGFαmRNA的表达,并发现TPA能提高人膀胱移行上皮癌BIU-87细胞中TCFαmRNA和TGFα活性分子的水平,但对TGFα的功能受体(EGF受体)具有负调节作用。提示TGFα在膀胱肿瘤细胞的恶性增殖过程中起一定作用,蛋白激酶C的激活可能是调节TGFα基因表达的途径之一。

xperimental studies on thetreatment of ratbladder

用高能冲击波治疗由N-甲基亚硝基脲诱导的大鼠膀胱肿瘤的实验研究,病理和电镜观察显示单次高能冲击波对膀胱肿瘤细胞无影响,连续两次高能冲击波处理后,48小时起出现肿瘤细胞坏死,随时间延长,肿瘤坏死增加。高能冲击波主要引起肿瘤细胞内线粒体肿胀等改变,从而导致细胞坏死,流式细胞仪检查示高能冲击波必理后S期细胞数明显下降。结果表明连续两次高能冲击波处理对膀胱肿瘤细胞确实存在直接和间接毒性作用。

Using Northern and dot blot analysis,we investigated the expressions of TGFα gene and some oncogenes in human bladder carcinoma cell line BIU-87. We found expressions of TGFαgene, c-myc, c-fos,erbB in BIU-87 cells-. In contrast, no expressions of these genes could be detected in normal bladder tissues as control. These data suggest that TGFα,c-myc,c-fos and erbB genes are responsible for the abnormal growth of bladder cancer.

本文应用Northern和Dot印渍分析检测了我国新建人膀胱癌细胞系BIU-87中TGFα基因以及某些癌基因的表达情况,发现BIU—87细胞中有TGFα、c—myc、c—fos、erbB等基因的表达,而作为对照的正常膀胱组织中没有检测到这些基因的表达。提示多种基因的异常表达在膀胱肿瘤细胞的恶性增殖过程中起一定的作用。

 
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