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性肾病综合征
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  idiopathic nephrotic syndrome
     The Lowering CD40L Expression of Peripheral T Lymphocytes and Hypo IgG in Children with Idiopathic Nephrotic Syndrome
     低CD40L表达在儿童单纯性肾病综合征低IgG血症发生中的作用
短句来源
     Purpose To invesigate the effect of glucocortioid on the nuclear protein level of glucocorticoid receptor(GR),activator protein-1(AP?1) and nuclear factor-kappa B(NF?κB),and the relationship between this effect and the glucocorticoid sensitivity in idiopathic nephrotic syndrome(INS).
     目的 探讨特发性肾病综合征 (INS)患者糖皮质激素受体 (GR)、核因子κB(NF κB)和活化蛋白 1(AP 1)的核内蛋白水平受糖皮质激素治疗的影响 ,以及这种变化与激素敏感性的关系。
短句来源
     We studied potential relationship between soluble interleukin-2 receptors (SIL-2R)levels and T lymphocyte subsets in 26 children with idiopathic nephrotic syndrome(INS).
     本文对26例儿童单纯性肾病综合征患者血清可溶性白细胞介素2受体(SIL-2R)及T细胞亚群进行研究。
短句来源
     Objective: To explore the effect of idiopathic nephrotic syndrome(INS)at active stage on bone metabolism in children.
     目的:探讨特发性肾病综合征(INS)活动期对儿童骨代谢的影响。
短句来源
     Detection of serum free thyroid hormones and its clinical significance in children with idiopathic nephrotic syndrome
     特发性肾病综合征患儿血清游离甲状腺激素检测的临床意义
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  “性肾病综合征”译为未确定词的双语例句
     Objective To detect the anti-C1q antibodies(C1qAb) levels in the patients with systemic lupus erythematosus (SLE) and non-lupus nephrotic syndrome, to assess the value of C1qAb in the diagnosis of lupus nephritis (LN) and to investigate the correlations between C1qAb and antinuclear antibody (ANA), antidouble-stranded DNA (anti-ds-DNA) antibody and systemic lupus erythematosus disease activity index(SLEDAI).
     目的检测系统性红斑狼疮(SLE)患者及非狼疮性肾病综合征患者的C1q抗体(C1qAb)的水平,探讨C1qAb在狼疮性肾炎诊断中的意义,并作C1qAb与抗核抗体(ANA)、抗ds鄄DNA和SLEDAI的相关性分析。
短句来源
     Effect and clinical significance of Tacrolimus on serum interleukin-2(IL-2),soluble interleukin-2 receptor(sIL-2R) expression in refractory nephrotic syndrome
     普乐可复对难治性肾病综合征患者血清IL-2、sIL-2R的影响及其临床意义
短句来源
     Methods CTX was given to 38 children with refractory NS in Zhuang nationality. The usage of CTX as followed: 8-12 mg/kg CTX and sodium chloride injection(or 10% glucose injection) 100 mL were given by intravenous drip for about 1 hour once a day,and last 8-10 days,the accumulated amount of CTX was less than 80-100 mg/kg.
     方法对38例壮族难治性肾病综合征患儿予CTX 8~12 mg/(kg.d)加入生理盐水或10%葡萄糖注射液100 mL,静滴1 h左右,1次/d,连用8~10次,累积量<80~120 mg/kg。
短句来源
     Methods The serum C1q antibodies in 106 patients with SLE,30 cases with non-lupus nephritic syndrome and 30 healthy controls were measured by enzyme-linked immunosorbed assay (ELISA).
     方法用ELISA对106例SLE、30例非狼疮性肾病综合征患者和30名健康对照者外周血血清中C1qAb进行检测。
短句来源
     Methods 171 children with frequently relapsing nephritic syndrome were chosen and given intravenous stosstherapy with CTX. CTX was administered in a dose of 8~12 mg/(kg·d) on the first 2 days of two weeks and for 6~9 times in all. Accumulated dose were 150 mg/kg averagely(120~180 mg/kg).
     方法选择171例频繁复发性肾病综合征患儿,均给予CTX静脉冲击治疗,具体方法:CTX 8~12 mg/(kg.d)加生理盐水或10%葡萄糖液100 mL静滴,每日1次,连用2 d,2周后再重复使用,共6~9次,总累积量平均150 mg/kg(120~180 mg/kg)。
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  相似匹配句对
     Das nephrotische Syndrom
     肾病综合征
短句来源
     Refractoriy Nephrotic Syndrome
     难治肾病综合征
短句来源
     Management of Idiopathic Nephrotic Syndrome in Children
     肾病综合征的治疗
短句来源
     Analysis on Intractable Nephrotic Syndrome
     难治肾病综合征探析
短句来源
     Views about Obstructive Nephropathy
     梗阻肾病
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  idiopathic nephrotic syndrome
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome
      
Treatment with cyclosporin of patients with idiopathic nephrotic syndrome
      
The prognosis of idiopathic nephrotic syndrome was transformed with the use of corticosteroids and immunosuppressive drugs.
      
Despite these drawbacks, preliminary results showed that approximately two-thirds of patients with idiopathic nephrotic syndrome resistant to other therapy clearly benefited from cyclosporin treatment, whereas only 7% suffered severe side effects.
      
Membranous nephropathy, a disease characterized by an accumulation of immune deposits on the outer aspect of the glomerular basement membrane, is the most common cause of idiopathic nephrotic syndrome in white adults.
      
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95 children with nephrotie syndrome were studied. The relation of sex, age, duration of attaek, edema, proteinurla, hematurila, blood pressure, urea nitrogen, plasma proteins, choesterol, immunoglobulin serum C_3, and the pattern of response toprednisone to the clinical cla sification of nephrotic syndrome were discussed. The diagnosis of refractory nephrotic syndrome may be facilitated by refering the following findings.age over 7, repeated appearance of R. B. C. and granular casts in urine, normal or increased...

95 children with nephrotie syndrome were studied. The relation of sex, age, duration of attaek, edema, proteinurla, hematurila, blood pressure, urea nitrogen, plasma proteins, choesterol, immunoglobulin serum C_3, and the pattern of response toprednisone to the clinical cla sification of nephrotic syndrome were discussed. The diagnosis of refractory nephrotic syndrome may be facilitated by refering the following findings.age over 7, repeated appearance of R. B. C. and granular casts in urine, normal or increased serum γ-globulin but diminution of C_3, persistence of abnormality in plasma proteins even after 4-8 weeks of prednisone treatment. Various infections are important factor, which usually made the treatment of nephrotic syndrome difficult.

本文对95例肾病综合征进行分析,探讨了性别、年龄、发病迁延时间、浮肿、蛋白尿、血尿、血压、尿素氮、血浆蛋白、血浆胆固醇、免疫球蛋白、补体C_3与激素反应及分型的关系。认为下列综合分析可做为判定难治性肾病综合征的参考。难治性肾病多分布在7岁以上,激素治疗4~8周血浆蛋白尚未恢复,尿镜检反复出现红细胞及颗粒管型,血清r—球蛋白不低,而补体C_3降低,提示难治性肾病。各种感染常常是造成肾病综合心难以控制,甚至死亡的重要因素。

A clinical and pathological study of 24 cases of childhood idiopathic nephrotic syndrome which displayed no response to steroids or relapsed frequently is presented. The pathological lesions were: mesangial proliferative glomerulonephritis (14 cases), minimal change disease (3 cases), membranoproliferative glomerulonephritis (3 cases), membranous nephropathy (2 cases), endocapillary proliferative glomerulonephritis(1 case), and focal segmental glomeruloscterosis (1 case). The incidence of mesangial proliferative...

A clinical and pathological study of 24 cases of childhood idiopathic nephrotic syndrome which displayed no response to steroids or relapsed frequently is presented. The pathological lesions were: mesangial proliferative glomerulonephritis (14 cases), minimal change disease (3 cases), membranoproliferative glomerulonephritis (3 cases), membranous nephropathy (2 cases), endocapillary proliferative glomerulonephritis(1 case), and focal segmental glomeruloscterosis (1 case). The incidence of mesangial proliferative glomerulonephritis in this group was 58.3%. It was felt that in the case of some non-responders, a prolonged course of alternate day steroid therapy might improve their prognosis.

本文报告对泼尼松治疗不效应和频繁复发的小儿难治性肾病综合征的临床及病理所见。其病理改变类型如下:系膜增殖性肾炎14例、微小病变3例、膜增殖性肾炎3例、膜性肾病2例、毛细血管内增殖性肾炎1例、局灶性节段性肾小球硬化1例。其中系膜增殖性肾炎占58.3%。对不效应者延长泼尼松隔日用药时间可能使其中部分病例缓解而改善预后。

Eighteen cases of refractory nephrotic syndrome were treated with the combined therapy of large dosage dexamethasone (DXM) and heparin.Compared with large dosage DXM alone, the combined therapy was more significant in reducing proteinuria and improving serum albumin level (p<0.01).The data showed that in the group of combined therapy 94.4% of the cases were totally effective and 83.3% obviously effective while in the group of DXM alone, 42.1% of the cases were totally effective and 10.5% were obviously effective.It...

Eighteen cases of refractory nephrotic syndrome were treated with the combined therapy of large dosage dexamethasone (DXM) and heparin.Compared with large dosage DXM alone, the combined therapy was more significant in reducing proteinuria and improving serum albumin level (p<0.01).The data showed that in the group of combined therapy 94.4% of the cases were totally effective and 83.3% obviously effective while in the group of DXM alone, 42.1% of the cases were totally effective and 10.5% were obviously effective.It is considered that the therapeutic result of the combined therapy is better then large dosage DXM alone, and the combined therapy is an effective method to treat refractory cases of nephrotic syndrome.

大剂量地塞米松联用肝素治疗“难治性”肾病综合征18例,单纯地塞米松冲击19例。前者尿蛋白明显减少,血清白蛋白明显上升,总有效率94.4%,显效率83.3%;近期疗效明显优于地塞米松组,可作为治疗“难治性”肾病综合征可取方法之一。

 
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