助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   肌球蛋白轻链 的翻译结果: 查询用时:1.276秒
图标索引 在分类学科中查询
所有学科
生物学
基础医学
心血管系统疾病
内分泌腺及全身性疾病
外科学
特种医学
消化系统疾病
急救医学
临床医学
更多类别查询

图标索引 历史查询
 

肌球蛋白轻链     
相关语句
  myosin light chain
     The phosphorylation and dephosphorylation of 20KD myosin light chains(MLC20) by Ca2±/ Calmodulin(CaM) dependent myosin light chain kinase (MLCK) and myosin light chain phosphatase (MLCP) play the key role for the regulation in smooth muscle contraction.
     平滑肌肌球蛋白轻链激酶(myosin light chain kinase,MLCK)对肌球蛋白20KD轻链(myosin light chains,MLC_(20))的Ca~(2+)/钙调蛋白(Calmodulin,CaM)依赖性磷酸化及肌球蛋白轻链磷酸酶(myosin light chain phosphatase,MLCP)对其的脱磷酸化是平滑肌收缩的主要调节机制。
短句来源
     RFLP analysis of ventricular myosin light chain 1 gene in families with congenital heart disease.
     先天性心脏病家系心室肌球蛋白轻链1基因的RFLP分析
短句来源
     RESULTS: TRE17 associated with 6 proteins, including pur alpha, myosin light chain 2, lactate dehydrogenase A, and troponin C2, as demonstrated by yeast two - hybrid. Among them, only troponin C2 interacted with both TRE17 and TRE17(447) .
     结果:酵母双杂交分析提示,癌基因TRE17可能结合6种靶蛋白,包括PUR ALPHA、肌球蛋白轻链2、乳酸脱氢酶A和肌钙蛋白C2等,其中,仅肌钙蛋白C2能够既结合全长的癌基因TRE17,又结合仅编码TRE17 氨基端447个氨基酸的TRE17(447)。
短句来源
     MLC2 (myosin light chain 2) is a regulatable protein by phosphorylating in heart.
     肌球蛋白轻链(myosin light chain-2,MLC2)在心脏中是一种可调控蛋白,通过磷酸化和去磷酸化作用而进行调控。
短句来源
     It was found that lower 20 ng/ml PDGF was able to induce the migration of GbaSM-4 cells, in which myosin light chain (MLC20) with phosphorylation was not necessary.
     研究结果显示,20ng/ml以下剂量的PDGF可诱导GbaSM-4细胞发生迁移,此时肌球蛋白轻链(MLC20)磷酸化水平无变化。
短句来源
更多       
  myosin light chains
     The phosphorylation and dephosphorylation of 20KD myosin light chains(MLC20) by Ca2±/ Calmodulin(CaM) dependent myosin light chain kinase (MLCK) and myosin light chain phosphatase (MLCP) play the key role for the regulation in smooth muscle contraction.
     平滑肌肌球蛋白轻链激酶(myosin light chain kinase,MLCK)对肌球蛋白20KD轻链(myosin light chains,MLC_(20))的Ca~(2+)/钙调蛋白(Calmodulin,CaM)依赖性磷酸化及肌球蛋白轻链磷酸酶(myosin light chain phosphatase,MLCP)对其的脱磷酸化是平滑肌收缩的主要调节机制。
短句来源
     A constitutively active myosin light chain kinase (MLCK) fragment (MLCKF) was found to phosphorylate myosin light chains (MLC 20) in a Ca 2+-CaM independent way more effectively than the intact MLCK.
     肌球蛋白轻链激酶 (MLCK)的活性片段 (MLCKF)能比完整的MLCK更有效地、以非钙依赖性的方式磷酸化肌球蛋白轻链 (MLC2 0 )。
短句来源
     Enzyme Linked Immunosorbent Assay for K D Value of Anti cardiac Myosin Light Chains (CMLC) Monoclonal Antibodies
     用ELISA法测定抗人心肌肌球蛋白轻链(CMLC)单克隆抗体的K_D值
短句来源
     The Characterization of MLCK Mediated Ca~(2+)-independent Phosphorylation of Myosin Light Chains
     肌球蛋白轻链的非Ca~(2+)依赖性磷酸化特征及其影响因素
短句来源
     An enzyme-linked immunosorbent assay (ELISA) for serum cardiac myosin light chains (CMLC), employing both monoclonal antibody (McAb) and antiserum, has been developed.
     单克隆抗体(McAb)和抗血清各有特点。 本文提纯人心肌肌球蛋白轻链(CMLC)并制备其单克隆抗体和抗CMLC兔血清(下称抗血清),试建立测定血清CMLC的酶联免疫(ELISA)方法。
短句来源
更多       
  myosin light chain 2
     RESULTS: TRE17 associated with 6 proteins, including pur alpha, myosin light chain 2, lactate dehydrogenase A, and troponin C2, as demonstrated by yeast two - hybrid. Among them, only troponin C2 interacted with both TRE17 and TRE17(447) .
     结果:酵母双杂交分析提示,癌基因TRE17可能结合6种靶蛋白,包括PUR ALPHA、肌球蛋白轻链2、乳酸脱氢酶A和肌钙蛋白C2等,其中,仅肌钙蛋白C2能够既结合全长的癌基因TRE17,又结合仅编码TRE17 氨基端447个氨基酸的TRE17(447)。
短句来源
     MLC2 (myosin light chain 2) is a regulatable protein by phosphorylating in heart.
     肌球蛋白轻链(myosin light chain-2,MLC2)在心脏中是一种可调控蛋白,通过磷酸化和去磷酸化作用而进行调控。
短句来源
     The expression of cardiac myosin heavy chain (MHC) and troponin Ⅰ (TnⅠ) was detected by using immunofluorescence,and the transcription promotion of the ventricular myosin light chain 2 (MLC2v) was detected with the enhanced cyan fluorescent protein (ECFP) reporter gene under the control of 250 bp MLC2v promoter;
     采用免疫荧光技术检测心肌特异性肌球蛋白重链 (MHC)及肌钙蛋白Ⅰ (TnⅠ )的表达 ,并用心室肌特异性肌球蛋白轻链 (MLC2v)启动子 (2 5 0bp)控制的蓝绿色荧光蛋白 (ECFP)报告基因表达技术从转录启动水平进行检测 ;
短句来源
     and the transcription promotion of the ventricular myosin light chain 2 (MLC2v) was detected with the enhanced cyan fluorescent protein (ECFP) reporter gene under the transcriptional control of MLC2v promoter (250 bp).
     并用心室肌特异性肌球蛋白轻链 (ventricularmyosinlightchain 2 ,MLC2v)启动子 (2 5 0bp)控制的增强型蓝绿色荧光蛋白 (enhancedcyanfluorescentprotein ,ECFP)报告基因表达技术检测被诱导MSCs是否发生MLC2v的转录启动。
短句来源
     Objective To investigate the gene expression of myosin heavy chain (αMHC、βMHC)、myosin light chain 2(MLC2A、MLC2V)and myosin light chain kinase(MLCK) in human atrial fibrillation (AF).
     目的探讨风湿性心瓣膜病伴心房颤动(AF)患者心房组织肌球蛋白轻链MLC2、肌球蛋白重链MHC、轻链激酶MLCK mRNA基因表达及βMHC蛋白表达的变化,并探讨其在房颤心房收缩重构中的意义。
短句来源
更多       
  “肌球蛋白轻链”译为未确定词的双语例句
     RESULTS:In the absence of Ca2+ /CaM,61 ku MLCKF phosphorylated MLC20 and stimulated myosin Mg2+ ATPase activity slightly but significantly.
     结果:在无Ca2+/CaM条件下,61kuMLCKF能轻度磷酸化20ku肌球蛋白轻链,并提高肌球蛋白Mg2+-ATP酶活性;
短句来源
     Peaks of CMLCs concentrations occurred on the day of2.2±1.2 (first peak) and the day of 7.1±1.9 (second peak). The twopeak-concentrations of CMLCs were 45. 7±33.5 and 62. 2±32. 9ng/ml,respectively. High level of CMCLs remained in patients for 11±3.4 days.
     轻链高峰在入院后第2.2±1,2d(第一峰)和7.1±1.9d(第二峰)出现,峰值分别是45.7±33.5ng/ml和62.2±32.9ng/ml,高水平肌球蛋白轻链在病人血中保持11±3.4d。
短句来源
     Myocardial nutrition blood flow (NBF ) was measured at burn before and 1, 3, 6, 12, 24h postburn with 86 Rb trace uptake techniqe.
     86Rb示踪摄取法测定大鼠烧伤前(对照组)和烧伤后1、3、6、12、24h心肌营养性血流(NBF)变化,同时监测血清心肌肌球蛋白轻链ICMLC1含量变化。
短句来源
     The Altered Gene Expression of MHC、MLC2、MLCK in Human Atrial Fibrillation
     心房颤动患者心房肌球蛋白轻链MLC2、肌球蛋白重链MHC、轻链激酶MLCK基因表达的研究
短句来源
     Taken together, it suggests that the signaling pathways are related to promoting the membrane translocation of PLCβ_2 by AA-activated Gi protein, furthermore resulting in migration of SM3 cells through enhancing phosphorylation levels of PKC (ε), ERK1/2, p38 and JNK, when phosphorylation of MLC20 was inhibited.
     上述结果表明,当肌球蛋白轻链的磷酸化被抑制后,AA可通过Gi蛋白的活化促进PLCβ2向细胞膜移位,进而通过激活PKC(ε)、ERK1/2、p38和JNK等信号转导途径而诱导SM3细胞发生迁移.
短句来源
更多       
查询“肌球蛋白轻链”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  myosin light chain
Ontogenetic and Phylogenetic Analysis of Myosin Light Chain Proteins from Skeletal Muscles of Loach Misgurnus fossilis
      
mRNAs of all three types of myosin light chain proteins are expressed in skeletal muscles of both larval and adult stages of loach Misgurnus fossilis (Cobitidae) and these proteins are encoded by different genes (mlc1, mlc2, and mlc3).
      
Our approach (RT-PCR with fish-specific mlc1, mlc2, and mlc3 primers) failed to reveal the larval form of myosin light chain protein found previously by protein electrophoresis of loach fry muscle extract.
      
Origin and structure of myosin light chain (MLC) proteins have been studied by comparative analysis of fish mlc1, mlc2, and mlc3 genes encoding MLC1, MLC2, and MLC3, respectively.
      
There is a possibility that the paralog of mlc1 encodes larval myosin light chain protein (larval MLC) previously reported in a number of fish species.
      
更多          
  myosin light chains
Comparative structural analysis of myosin light chains and gene duplication in fish
      
Phosphorylation of myosin light chains as a result of activation of myosin light chain kinase and inactivation of myosin phosphatases stimulates stress fiber formation and triggers actomyosin contraction.
      
We studied myosin light chains (LC) of human atrium and ventricle of normal and diseased individuals by a high-resolution 2-dimensional polyacrylamide gel electrophoresis (2D-PAGE) technique.
      
The explanation for this finding in ventricles still remains obscure since neither myosin light chains, nor myosin heavy chains showed any difference between patients with dilated cardiomyopathy and controls.
      
These effects were accompanied by changes in the extent of phosphorylation of troponin I (TNI) and myosin light chains.
      
更多          
  myosin light chain 2
The main muscle-fibre type of larvae, and the fast- and slow-muscle fibres of adult fish were found to contain distinct isoforms of myosin heavy chain (MHC) and myosin light chain 2 (LC2).
      
However, four genes, pyridoxal kinase, heat shock protein 10 (Hsp10), antigen identified by monoclonal antibodies 4F2 (4F2) and myosin light chain 2, were downregulated by SNAP in presence of AP-1.
      
One promoter (CK), derived from a cytokeratin gene, is active specifically in skin epithelia in embryos, and the other promoter (MLC) from a muscle-specific gene encodes a myosin light chain 2 polypeptide.
      
During normal development in rats, myosin light chain 2 expression is very low at prenatal stages, while c-fos expression starts from the early stages of embryonic development.
      
In aorta constricted rats c-fos induction occurs within 30 min whereas myosin light chain 2 expression is sufficiently high only after 3 or 4 days of post operative period.
      
更多          
  其他


According to the analysis on light chain pattern of single fibers, there were one third of fibers in rat soleus muscle which had a distinct staining band at the position of LC3, while the remaining fibers did not show such band by present method due to its minute quantity. No matter whether or not LC3 appeared, the electrophorctic patterns of fiber proteins between Sol and EDL were completely different, including the differences of molecular weights of LQ, LC2 and the distance travelled along the gel between...

According to the analysis on light chain pattern of single fibers, there were one third of fibers in rat soleus muscle which had a distinct staining band at the position of LC3, while the remaining fibers did not show such band by present method due to its minute quantity. No matter whether or not LC3 appeared, the electrophorctic patterns of fiber proteins between Sol and EDL were completely different, including the differences of molecular weights of LQ, LC2 and the distance travelled along the gel between LC1 and tropomyosin of fibers of the two muscles. Experiments have been performed to see if LC3 exists in each fiber of soleus muscle. We deduced it by analyzing randomly three fibers in one electrophorctic gel to show the chance of appearance of LC3 by simple probability calculation and a great exceed (89%) over the 'theoretical' value (67%) in probability was achieved. For the same purpose, we also analyzed guinea pig soleus which was known to have pure slow fibers, and conform to that, 100% of fibers tested contained LC3; and finally 56% of cat soleus fibers was found to contain LC3 whose appcarncc were clearly related to their intensity of protein staining on clectrophoretic gels.

从整块肌肉抽提的肌球蛋白,其轻链类型因肌肉收缩的快慢而有区别,即快肌的肌球蛋白有三条轻链,慢肌的肌球蛋白只有二条轻链(Sarker等,1971;Lowey和Risby,1971),它们分别属于不同的肌球蛋白同功酶,这在鸡(Hoh,1978)和兔(Hoh,1979)都是这样。另外,在神经肌肉的发育过程中,一旦有了神经控制,便使起初只合成快型轻链的肌肉,逐步向合成慢型轻链的慢肌分化(Rubinstein和Kelly,1978)。然而,快肌和慢肌不同的轻链图谱特征,是否也表现在肌纤维的快慢类型上呢?这很少见到报道。我们曾观察到单肌纤维的肌球蛋白有二个成份,它们之间的比值和各自的电泳迁移率可以作为区别二类不同单肌纤维的特征(章生艮、任惠民,1983)。我们认为既然快肌纤维和慢肌纤维的肌球蛋白成份各有特征,那末,单肌纤维的肌球蛋白轻链图谱,当然也应该能反映单肌纤维的快、慢类型了。本文目的就是利用毛细管凝胶电泳对单肌纤维的轻链分析,来探讨这个问题。

Cd2 + and Hg2+ were found to mumic the stimulatory action of Ca2 + on calmodulin-dependent myosin light chain kinase ( MLCK ) from chicken gizzards. Hg2 + , however, was less effective. The effect induced by Cda+ and Hg2+ were biphasic, stimulatory at low concentrations and inhibitory at high concentrations. The activation by Cd2+ of MLCK was inhibited by, chlorpro-mazine, a calmodulin antagonist. These facts may help to explain mechanism

应用平滑肌肌球蛋白轻链激酶(MLCK)体系,观察了重金属离子Cd~(2+)和Hg~(2+)对MLCK活性的影响,得到以下结果:1.Cd~(2+)和Hg~(2+)对MLCK具有双相作用,低浓度下激活MLCK,高浓度下抑制MLCK;2.Cd~(2+)对MLCK的激活作用,被钙调素拮抗剂氯丙嗪所抑制;3.疏基化合物能逆转Cd~(2+)和Hg~(2+)对MLCK的抑制。结果提示,Cd~(2+)和Hg~(2+)能通过活化caM使MLCK激活,高浓度时直接作用于MLCK抑制其活性。

(DNPm-CaM) n-BSA was prepared by modifying the porcine brain ealmodulin(CaM)which had been shown to be homogeneous by SDS-PAGE, and then was used to immune California white rabbits. The antiserum obtained was tested for its immunoreaction by means of ELISA against native bovine brain CaM, native porcine brain CaM, CaBP72(Ca2+ binding protein 72KDa ) , CaN ( calcineurin ) and TnI ( inhibitor troponin ) , showing the cross-reaction ratios were 100, 100, 0.7, 0.4 and 0.02%respectively; while no cross-reaction occurred...

(DNPm-CaM) n-BSA was prepared by modifying the porcine brain ealmodulin(CaM)which had been shown to be homogeneous by SDS-PAGE, and then was used to immune California white rabbits. The antiserum obtained was tested for its immunoreaction by means of ELISA against native bovine brain CaM, native porcine brain CaM, CaBP72(Ca2+ binding protein 72KDa ) , CaN ( calcineurin ) and TnI ( inhibitor troponin ) , showing the cross-reaction ratios were 100, 100, 0.7, 0.4 and 0.02%respectively; while no cross-reaction occurred against CaBP11, CaBP12, TnT ( tropotroponin), TnC ( Ca2+ combining troponin ) , S100, and MIC ( myosin light chain ) . Immonoblotting technique for CaM demonstrated 2 bands appearing in the panel of the supernatant of homogenized rat brain; one was apparent and occupying a position corresponding to that of standard CaM and the other one was rather faint and representing a molecular weight less than that of CaM. The supernatanes from other rat organs ( liver, testis and heart ) gave just one and the same band as the standard CaM.

将从猪脑中所得SDS—PAGE纯的钙调素进行化学修饰,得(DNPm—CaM)n—BSA。将此修饰物免疫California白兔得抗血清。钙调素的ELISA测定表明:抗血清与天然牛脑和天然猪脑钙调素、CaBP_(72)(钙结合蛋白,分子量72KDa)、CaN(神经钙蛋白)、TnI(肌钙蛋白抑制亚单位)的交叉反应率分别为100%、100%、0.7%、0.4%、0.02%;与CaBP_(11)、CaBP_(12)、TnT、TnC、S—100、MLC(肌球蛋白轻链)均无交叉反应。免疫转移鉴定技术示:大鼠脑匀浆上清液显示强弱两条区带,强染色带相当于钙调素的位置,弱显色带分子量小于钙调素;其它所测大鼠组织匀浆上清液只在钙调素位置显示单一区带。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关肌球蛋白轻链的内容
在知识搜索中查有关肌球蛋白轻链的内容
在数字搜索中查有关肌球蛋白轻链的内容
在概念知识元中查有关肌球蛋白轻链的内容
在学术趋势中查有关肌球蛋白轻链的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社