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  immortals
     Morphometric Study on Influence of Modified “Two Immortals Decoction" on Atrial Specific Granules in Rats with Experimental Cerebral Ischemia
     二汤加减对实验性脑缺血大鼠心房特殊颗粒影响的体视学研究
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     A Doubt About the Source of 14 Tales of Immortals Included in Volume 113(the first half)of Seven Taoist Books in a Cabinet
     《云笈七籖》卷113(上)所收14则传归属置疑
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     Research on the Editions and Writer of the Immortals in Wilderness
     《绿野踪》版本、作者再证
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     On Cultural Constitute of He's Nine Immortals Belief
     试论何氏九信仰的文化构成
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     The picture of the Immortals F lying to the Heavens and Vimalakirti Sutra: the Painting on the Ceiling of Cave 249 at Mogao Grottoes Revisited
     上士登图与维摩诘经变——莫高窟第249窟窟顶壁画再探
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     The Study of SangXian Granule's Influence to the Quality of Life of Patients with Senile Hypertension and the Protective Effect on Kidney
     桑颗粒对中老年高血压病患者生活质量的影响及肾保护作用的研究
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     Study of Mifepristone Related Adnormal Menstruation and Xianche Decoction Recovering Mechanism
     米非司酮引起月经异常及车饮修复作用的机制研究
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     The Comprehensive Study of Reservoir of Feixianguan Formation in Lower Triassic Series, Northeast Sichuan
     川东北地区下三叠统飞关组储层综合研究
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     X PERSEI AND X-RAY SOURCE 3U0352+30
     英X与X射线源3U0352+30
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     STUDIES ON THE ACTIVE PRINCIPLES OF SHIANHOTSAO--Ⅱ.THE STRUCTURES OF AGRIMOL A,B,D AND E
     鹤草有效成分的研究--Ⅱ.鹤草酚A,B,D和E的结构
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     A Study on Pu-Xian Dialect
     莆方言研究
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     Review on the Biographies of the Taoist Immortal
     道教传述略
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  immortals
The Images of Immortals and Eminent Monks: Religious Mentality in Early Medieval China (4-6?c.
      
A preliminary discussion on Daoist bionomy: On the basis of Chen Yingning's philosophy of immortals
      
Chen Yingning reestablished a Daoist bionomy through Xianxue 仙学 (Philosophy of Immortals) which involves religious faith, philosophy and sciences, leaving us a valuable legacy.
      
The reason why he longed day and night to visit the immortals in the grottos of the mountains in Yue is also related to Qiang culture.
      
At the very least, oligarchs like Bush see themselves as demigods occupying a middle ground between the immortals above and the hoi poloi below.
      
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The "Compound Mixture of Two Fairies" has been used clinically for treatment of hypertension. It is composed of Curculigo ensifolio, Epimedium, sp., Morinda officinalis, Phellodendron chinense, Anemarrhena asphodeloides, and Angelica sinensis. In normal dogs, intragastric administrations of 6g (crude drugs) per kg t.i.d, for 20 days produced no toxic reactions: If the dosage was increased 3—4 times, emesis and diarrhea occurred, probably due to alimentary disorder from the bulk of the decoction. When the Compound...

The "Compound Mixture of Two Fairies" has been used clinically for treatment of hypertension. It is composed of Curculigo ensifolio, Epimedium, sp., Morinda officinalis, Phellodendron chinense, Anemarrhena asphodeloides, and Angelica sinensis. In normal dogs, intragastric administrations of 6g (crude drugs) per kg t.i.d, for 20 days produced no toxic reactions: If the dosage was increased 3—4 times, emesis and diarrhea occurred, probably due to alimentary disorder from the bulk of the decoction. When the Compound Mixture was introduced 6. g/kg into the lumen of duodenum in anesthetized cats, the blood pressure began to descend at 30 minutes, and lowered an average of 30% below the original level in 2 hours. Four Goldblatt renal hypertensive dogs were given the Compound Mixture by stomach tube. The dose for the first 10 days Was 9 g/kg/day, and doubled for the next, 10 days. The post-medication observation period was another 10 days. Blood pressure was measured daily by auscultation on the carotid loop. The average reduction of the diastolic pressure in the space of 30 days was 10 mm Hg (8%), and that for the lowest 5 days running was 16 mm Hg (12%). A therapeutic action (a reduction of at least 11 mm Hg diastolic) was demonstrated in 3 dogs. Among them 2 dogs received a second course of treatment which appeared to be equally efficacious. Intraperitoneal injections of the Compound Mixture 6 g/kg to anesthetized dogs resulted in a decrease of cardiac output during the hypotension, while the dilatation of peripheral vessels was insignificant. Comparative experiments on the 6 ingredients revealed that the hypotensive action of "Compound Mixture of Two Fairies" could be primarily attributed to Phellodendron chinense and Epimedium sp., whereas Curculigo ensifolio alone had little effect. Eight hypertensive dogs were fed daily the Compound Mixture or a mixture of 6 decoctions of the components. Analysis of variance disclosed that the hypotensive potency of the former was no better than the latter. Hypertensive dogs were fed the Compound Mixture which was devoid of Morinda officinalis, and the therapeutic potency was shown to be no less than that of "Compound Mixture of Two Fairies". Hence, we deem that Morinda officinalis is dispensable.

复方“二合剂”由茅、淫羊藿、巴戟天、黃蘗、知母及当归組成,所用药液均为水煎剂。正常狗每日灌胃給二合剂18克/公斤,連服20天,无毒性反应。增加剂量3—4倍,則有嘔吐泄泻,可能由于药液容量过大,影响消化道的机能。麻醉猫十二指腸注射二合剂6克/公斤,30分钟后血压开始下降,2小时后平均降低原水平的30%。慢性腎型高血压狗斗只,每日灌胃給二合剂2次,第1—10天剂量为9克/公斤/天,第11—20天剂量为18克/公斤/天,停药10天。舒张压“30天平均降压值”平均为10毫米汞柱(8%),“最低5天降压值”平均为16毫米汞柱(12%)。4狗中3狗呈現疗效(舒张压下降11毫米汞柱或以上),其中2狗重复一次試驗依然降压有效。麻醉狗腹腔注射二合剂6克/公斤,在急性降压时有心脏指数的减少,而外周血管的扩张并不明显。单味药的比較試驗証明黃蘗和淫羊藿为二合剂降压作用的主要有效成分,而茅几无降压效能。高血压狗8只,每天服二合剂或分煎合剂,变异数分析証明分煎合剂的降压效果不亚于二合剂。高血压狗灌胃...

复方“二合剂”由茅、淫羊藿、巴戟天、黃蘗、知母及当归組成,所用药液均为水煎剂。正常狗每日灌胃給二合剂18克/公斤,連服20天,无毒性反应。增加剂量3—4倍,則有嘔吐泄泻,可能由于药液容量过大,影响消化道的机能。麻醉猫十二指腸注射二合剂6克/公斤,30分钟后血压开始下降,2小时后平均降低原水平的30%。慢性腎型高血压狗斗只,每日灌胃給二合剂2次,第1—10天剂量为9克/公斤/天,第11—20天剂量为18克/公斤/天,停药10天。舒张压“30天平均降压值”平均为10毫米汞柱(8%),“最低5天降压值”平均为16毫米汞柱(12%)。4狗中3狗呈現疗效(舒张压下降11毫米汞柱或以上),其中2狗重复一次試驗依然降压有效。麻醉狗腹腔注射二合剂6克/公斤,在急性降压时有心脏指数的减少,而外周血管的扩张并不明显。单味药的比較試驗証明黃蘗和淫羊藿为二合剂降压作用的主要有效成分,而茅几无降压效能。高血压狗8只,每天服二合剂或分煎合剂,变异数分析証明分煎合剂的降压效果不亚于二合剂。高血压狗灌胃試驗二減巴合剂,降压效果并不較二合剂为弱,所以我們建議复方二合剂中可減省巴戟天。

In normal dogs intragastric administration of the decoction of the leaves of C.trichdtomum induced emesis after a single dose of 20g(crude drug)/kg or more,but no emesis below 10g/kg. Daily administration of 10g/kg for 3 weeks rendered no significant changes in the liver function, blood picture,EKG,and pathologic examination. Five Goldblatt renal hypertensive dogs were used for the experimental therapy.Blood pres- sure was measured by auscultation on the carotid loop.C.trichotomum was given 10g/kg/day for 4...

In normal dogs intragastric administration of the decoction of the leaves of C.trichdtomum induced emesis after a single dose of 20g(crude drug)/kg or more,but no emesis below 10g/kg. Daily administration of 10g/kg for 3 weeks rendered no significant changes in the liver function, blood picture,EKG,and pathologic examination. Five Goldblatt renal hypertensive dogs were used for the experimental therapy.Blood pres- sure was measured by auscultation on the carotid loop.C.trichotomum was given 10g/kg/day for 4 weeks.Hypotension began in the 2nd week,and became more marked on further medication. The weekly average diastolic pressure decreased 32,17,6,20,and 12 mm Hg(25%,14%,5%, 16%,and 10%) respectively.The liver function and the blood picture were apparendy unaltered. After 3 weeks of medication the T wave in the EKG was found to be inverted in 3 dogs. When compared with the therapeutic activities of the Chinese drugs previously tested on the hypertensive dogs in this laboratory,C.trichotomum is probably less effective than Veratrum Schindleri,Scutellaria baicalcnesis,and the total alkaloids from Rauwolfia wrticillata,is similar to the Compositus Erxian-heji,but is better than Eucommia ulmoides.

正常狗灌胃海州常山叶水煎剂1次20g/kg以上即嘔吐,10g/kg以下无嘔吐。每天灌胃10g/kg,共3周,肝机能、血象、心电图及病理检查均无明显改变。慢性腎型高血压狗5只,听诊测量颈动脉皮桥血压。每日灌胃10g/kg,共4周。在给药第2周降压作用开始显著,继续给药则降压更多。每周平均舒张压低时分别下降32,17,6,20,12mmHg(25%,14%,5%,16%,10%)。心搏率、肝机能及血象无明显变化、给药第3周以后3只狗心电图T波变为倒置。与本实验室过去以慢性腎型高血压狗口服几种中药相比较,海州常山比藜芦、黄芩及蘿芙木全硷的降压效力可能稍差,与二合剂相差不多,但比杜仲较好。

The "Compound Mixture of Two Fairies" (Ⅰ) has been used as a hypotensive drug. One of its chief ingredients is Phellodendron chinense (Ⅱ). Berberis spp. (Ⅲ)contains also much berbcrine. Hence Ⅱhas been substituted by Ⅲ in making the Compound Mixture Ⅳ. In this paper Ⅱand Ⅲ were studied in the form of fluidextracts. The dosages used were expressed in terms of crude drugs. The intraperitoneal LD_(50) in mice were 2.7 g/kg for Ⅱ and 3.1 g/kg for Ⅲ. Intraperitoneal injections in anesthetized cats produced, in...

The "Compound Mixture of Two Fairies" (Ⅰ) has been used as a hypotensive drug. One of its chief ingredients is Phellodendron chinense (Ⅱ). Berberis spp. (Ⅲ)contains also much berbcrine. Hence Ⅱhas been substituted by Ⅲ in making the Compound Mixture Ⅳ. In this paper Ⅱand Ⅲ were studied in the form of fluidextracts. The dosages used were expressed in terms of crude drugs. The intraperitoneal LD_(50) in mice were 2.7 g/kg for Ⅱ and 3.1 g/kg for Ⅲ. Intraperitoneal injections in anesthetized cats produced, in 90 minutes, an average “% of hypotensive areas”of -30%for Ⅰ(4g/kg),—30% forⅡ(2g/kg),—42% for Ⅲ(2g/kg), and —32% for Ⅳ(4g/kg). Six renal hypertensive dogs were fed Ⅳ 15—30 g/kg/day for 20 days. There were no remarkable changes in blood pressure, EKG, BSP retention, and blood NPN. Three normal dogs were fed daily Ⅳ 45 g/kg for 3 weeks. Abnormal alteration was not found in EKG, liver and kidney function tests, nor was toxic sign noticed in the microscopic examinations. Sixteen water-soluble portions from different fractions of Ⅲ were screened over by single intravenous injections in anesthetized cats, 2—3 cats for each portion. Six of them yielded an average“%of hypotensive areas” exceeding —30%. Since Ⅲ is abundant in China and low in toxicity, it seems to be a promising source of hypotensive drugs.

复方二合剂降压有效,其中以黄蘗的降压作用較強。三顆針是小蘗科植物,与黄蘗同为小蘗碱的資源植物,来源充沛。本文試驗其毒性与疗效。小白鼠腹腔注射1次三顆針或黃蘗流浸膏,观察3天的LD_(50)各为3.1与2.7克生药/公斤,相差不显著。麻醉猫腹腔注射三顆針或黄蘗流浸膏2克/公斤,90分钟內平均降压面积百分比:三顆針組为-42%,黃蘗組为-30%,相差显著。而注射針合剂(三顆針代黄蘗加入二合剂)或二合剂4克/公斤,90分钟內的平均降压面积百分比均为-30%左右。 腎型高血压狗每天灌服針合剂15—30克/公斤,共20天,血压变化不明显。心电图、肝对磺溴酞鈉的排泄机能及全血非蛋白氮量的測定,无明显改变。正常狗每天灌服針合剂45克/公斤,3周后,检查心电图、肝及腎机能无异常,其中1狗內脏作組織切片,无明显中毒現象。对麻醉猫靜脉注射由三顆針提取的不同部位的水溶液2—10毫克/公斤,篩过16种成分,其中6种的平均降压面积百分比超过-30%。三顆針药源广、口服毒性小,是一种較有希望的降压药源。

 
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