Methods Endothelin-1 (ET-1), thrombomodulin (TM), P-selectin, prothrombin fragment _ 1+2 (F_ 1+2 ), thrombin-antithrombin complex (TAT), thrombus precursor protein (TpP) and D-Dimer (D-D) were measured in DVT patients (n=72) and normal individuals (n=20) with ELISA method.
Results Total misdiagnosis rate of the first consultation in 48 acute PE patients was 72.9%,79.2% of those had hypoxemia and/or hypocapnemia,91.7% of those showed D-dimmer positive(>500 μg/L),85.4% of those have typical changes on UCG,87.5% patients showed filling-defect at or above pulmonary segmental artery level.
For the first time the destabilase-specific D-dimer-monomerizing and lysozyme activities were separated by fractionation of secretion-I by HPLC gel filtration through Superose S-12.
D-dimer we obtained has a pronounced inhibitory effect on fibrin polymerization (IC50 = 0.06 μM).
D-dimer dimer and FDP level increased at 24 hours and 48 hours in both groups(P>amp;lt;0.05), but returned to the baseline level 24 hours post IABP removal (P>amp;gt;0.05).
Oxygenation index, D-dimer, fibrinogen (FG), lung ventilation/perfusion (V/Q) scan and computed tomography pulmonary angiography (CTPA) were observed before anticoagulation and on day 14 after anticoagulation.
Our study demonstrated a significant stronger and faster decline of coagulation parameters - such as d-dimer, TAT and PTF 1 + 2 - in the High dose group without any bleeding disorder.
There were high plasma concentrations of D dimer, thrombin-antithrombin complexes or prothrombin fragments 1 and 2, further supporting the neuroimaging diagnosis of CVT.
D-D dimer and α2-plasma inhibitor (α2-PI) were detected to observe fibrinolytic state.
The results showed that no difference existed between SA group and normal controls, while both D-D dimer and α2-PI in UA group and AMI group were significantly elevated than those in SA group and normal controlsP>amp;lt;0.
Rotational Invariance and Discrete Analyticity in the 2d Dimer Model
We exploit the discrete analytic structure present in the 2d dimer model to rigorously compute the exponents of a class of two point functions in all directions.