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This communication is an analysis of the scanning results of sixty cases of clinically suspected hepatic space-occupying lesions which were subsequently pathologically proved. This series comprises 36 cases of primary carcinoma of the liver, 8 eases of metastatic carcinoma of the liver, 3 eases of schistosomal granuloma of the liver, 2 eases of liver cyst, 2 cases of liver abscess, and 1 case each of secondary mesothe-lioma of liver, cavernous haemangioma of liver,lymphangioma of liver, adenocarcinoma of gall-bladder,...

This communication is an analysis of the scanning results of sixty cases of clinically suspected hepatic space-occupying lesions which were subsequently pathologically proved. This series comprises 36 cases of primary carcinoma of the liver, 8 eases of metastatic carcinoma of the liver, 3 eases of schistosomal granuloma of the liver, 2 eases of liver cyst, 2 cases of liver abscess, and 1 case each of secondary mesothe-lioma of liver, cavernous haemangioma of liver,lymphangioma of liver, adenocarcinoma of gall-bladder, retroperitoneal undifferentiated carcino-ma, carcinoma of transverse colon, congenital intrahepatic cholangiectasis, carcinoma of panc-reas and cholecystitis. We could observe the configuration, struct-ure, location and size of the liver by this method.Each kind of hepatic space-occupying lesions had its own characteristic appearences in the liver scans.When a positive finding in the liver scan,was obtained, no single case was mistaken; but in case of negative finding in the liver scan, the possibility of space-occupying lesions could not be ruled out. Fifty-nine cases in this series showed typical changes in the liver scans, only one case of primary carcinoma of the liver exhibited no area of decreased activity in the liver scan, thus produeing false-negative result.Radioisotope scanning of the liver is accurate and painless and is considered to be the best method in the diagnosis of hepatic spaceoccupying lesions, particularly in the diagnosis and differ-ential diagnosis of carcinoma of the liver.

肝脏扫描术对肝脏占位性病变的诊断有很大的价值。我们总结了我院附属中山医院1959年以来300余例肝脏扫描中,经病理证实的60例临床上疑似肝脏占位性病变的扫描结果。本文着重讨论肝癌在扫描图上的表现及其与其他占位性病变的监别诊断,以及本方法和其他诊断方法的对比等。

The normal values of the serum γ-Gt activity in 110 healthy adultdonors were less than 50 units and those of the 9 newborns ranged from107 to 334 units. The γ-Gt of 48 patients suffermg from carcinoma of the liver increasedby 100%, those with γ-Gt over 200 units made up 79.5%. The α-FPdetermination and radioisotopic scanning simultaneously performed in 37cases were positive in 70.6% and 92.5% respectively. In comparison withγ-Gt determination it appeared that the latter was more sensitive thanthe formers. γ-Gt...

The normal values of the serum γ-Gt activity in 110 healthy adultdonors were less than 50 units and those of the 9 newborns ranged from107 to 334 units. The γ-Gt of 48 patients suffermg from carcinoma of the liver increasedby 100%, those with γ-Gt over 200 units made up 79.5%. The α-FPdetermination and radioisotopic scanning simultaneously performed in 37cases were positive in 70.6% and 92.5% respectively. In comparison withγ-Gt determination it appeared that the latter was more sensitive thanthe formers. γ-Gt of 1 patient of carcinoma of the pancreas was 1, 098 units,3 casesof carcinoma of the billiary tract ranged from 76.9 to 663 units. Therise of γ-Gt of these patients was closely related to the obstruction ofbilliary tract and/or metastasis into the liver. There were 13 cases of hepatitis with jaundice, of which 12 caseshad a rise of γ-Gt (66.5-446 units), but one case of severe hepatitisshowed only 50 units. Among 15 patients of cirrhosis of the liver,11 had a rise of γ-Gt, 4 of them returned to normal level in the latestage. One patient of acute schistosomiasis showed high levels of γ-Gt, butupon treatment it gradually decreased to normal. Among 15 cases of billiary tract diseases 13 showed rise in γ-Gt(101.5-516 units), while 2 were normal. In 2 patients with acute billiarydiseases γ-Gt was originally highly raised, later decreased gradually after the drainage. of common bile ducts. It therefore seemed that the rise ofγ-Gt was related to the obstruction of the billiary tract. To sum up, the determination of γ-Gt in serum was definitely valu-able for the diagnosis of diseases of the liver and billiary tract, espe-cially for primary as well as secondary carcinoma of the liver.

本文作者报告用自行合成的γ—L—谷氨酸—α萘胺为基质用改良法测定110名健康献血员、9名新生儿和167例患者血清γ—谷氨酰转肽酶(γ—GT)的结果。作者认为血清γ—GT的测定对肝胆系统疾病,特别是肝癌有一定的诊断价值。

Nine pathologically verified cases of double primary carcinomas of the esophagus and stomach are analyzed. All of the patients are males over the ages of 50. Barium meal roentgenography showed evidence of a lesion in the esophagus preope-ratively in each case. Pathological examination of the resected specimens revealed that there was another cancer in either the cardia or esophagus apart from the already discovered one. The cancer in the esophagus are in the main squmous cell carcinomas in the advanced stage....

Nine pathologically verified cases of double primary carcinomas of the esophagus and stomach are analyzed. All of the patients are males over the ages of 50. Barium meal roentgenography showed evidence of a lesion in the esophagus preope-ratively in each case. Pathological examination of the resected specimens revealed that there was another cancer in either the cardia or esophagus apart from the already discovered one. The cancer in the esophagus are in the main squmous cell carcinomas in the advanced stage. Among those in the cardia, 8 are adenocarcino-mas or adenosqumous carcinomas ( 3 are early adenocarcinomas ), where as in one case the double primary squmous cell carcinomas are located in the esophagus and cardia. The shortest distance between the double cancers is 2 cm. While the longest distance is 7 cm. Among 7 patients that have been followed up, 2 surived more than ten years. A brief review of the literature regarding carcinogenesis of double primaries in the esophagus and stomach is made. Field canceri/ation theory as advocated by slaughter in 1953 has been given attention. It seems that close observations have shown that cancer areses from a wide field rather than one point. It is assumed that the same carcinogenic agent may exert its effect over a wide field in the organs involved so that the carcinomatous changes in the neighbouring organs such as the esophagus and stomach can take place. They may either be simultaneous or occur one after the other. The material in this series may speak in favour of this theory. The author holds that the detailed examination of the neighbouring organs should be emphasized during the diagnosis of an esophageal cancer.

本文报告9例食管与胃的双原发癌。术前X线钡餐造影仅发现食管癌,术后病理检查,在贲门部又发现有另一个原发癌。其中食管病变均为鳞状细胞癌,且为晚期病变。贲门部病变中,8例为腺癌或腺鳞癌,1例为食管与贲门的双原发鳞状细胞癌。双原发癌间的距离为2~7厘米。在7例已经随访的病例中,2例术后10年健在。作者简要地复习了有关食管、胃双原发癌的文献,认为生癌野(Field Cancerization)学说值得重视;并提出在食管癌诊断与处理的过程中,必须注意相邻器官另一个原发癌存在的可能性。

 
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