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侵袭
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  invasion
    Inhibition of CD147 Expression Reduces Tumor Cell Invasion in Human Prostate Cancer Cell Line via RNA Interference
    针对CD147 RNA干扰对前列腺癌PC-3细胞系侵袭作用的影响
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    【Conclusion】HIF-1α protein is frequently expressed in BTCC,HIF-1α may play a critical role in the invasion of BTCC and can be used to estimate its progression.
    【结论】在BTCC中,HIF-1α蛋白的表达明显上调,HIF-1α在BTCC的侵袭等生物学过程中具有重要的作用,HIF-1α可能可以用于临床监控BTCC的进展。
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    Conclusions Loss E-cadherin expression was associated with nephroblastoma,Positive expressions ofβ-catenin and MMP-7 are associated with invasion and metastasis of nephroblastoma.
    结论E-cadherin蛋白的阳性表达缺失参与了肾母细胞瘤的恶性转化,而β-catenin和MMP-7的阳性表达促进了肾母细胞瘤的侵袭转移。
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    The expression of MMP 2 and MMP 9 in transitional cell carcinoma of bladder and its correlation to the tumor invasion and metastasis
    MMP_2及MMP_9在膀胱癌中的表达及在侵袭转移中的作用
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    Study of the relation between Invasion and metastasis of prostate carcinoma and the expression of tumor markers
    肿瘤标记物的表达与前列腺癌侵袭和转移的关系研究
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  invasiveness
    Study of Invasiveness and Local Invasion of Bladder Carcinoma by Helical CT
    螺旋CT对膀胱癌侵袭性及局部侵袭范围的研究
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    Vibramycin inhibits the expression of MMP-2 and the invasiveness of PC-3 cells in vitro
    强力霉素抑制PC-3细胞基质金属蛋白酶-2表达及侵袭的体外研究
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    Ultrasonographic observations on proliferative activity and invasiveness of rabbit renal VX_2 tumor
    兔肾VX_2肿瘤模型超声显像与肿瘤增殖活性及侵袭性的关系
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    Therefore, This research was designed to study the relationship between COX-2 and angiogenesis and invasiveness in human transitional cell carcinoma(TCC) from three aspects: The relationship between COX-2'expression and invasive state and microvessel density (MVD) in TCC specimens;
    因此,本研究以移行细胞癌(TCC)为研究对象,从下面三个方面研究COX-2及NSAIDs与肿瘤血管生成和侵袭转移能力的关系:临床TCC肿瘤标本中COX-2表达与侵袭和微血管密度MVD的关系;
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    Conclusions TGF β1 and TGFα do not inhibit the proliferation of EJ cells whereas the enhanced invasiveness and metastasis may be associated with regulating the expression of MMPs and TIMP 2.
    无论在对照组和实验组均未检测到MMP 9。 结论 TGF β1、TGF α不能抑制EJ细胞生长 ,参与肿瘤侵袭和转移作用可能与调节MMPs、TIMP 2表达途径有关
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    FIBRONECTIN AS A BIOLOGICAL TUMOR MARKER FOR BLADDER CANCER
    以纤维连接蛋白为标记物对膀胱癌侵袭及转移机制的研究
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    Significance of Activated Matrix Me talloproteinase 2(MMP2)in Progression of Bladder Transitio nal Cell Carcinoma
    MMP2活性测定在判断膀胱移行细胞癌侵袭性中的意义
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    The Expression of MMP2, MMP9, Type Ⅳ Collagen and E - CD in Bladder Transitional Cell Carcinoma and Its Clinical Significance
    Ⅳ型胶原酶和E-CD在膀胱移行细胞癌侵袭转移中的作用
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    Relationship between expression of vascular endothelial growth factor receptor flt-1 and metastasis in renal cell carcinoma
    肾细胞癌中血管内皮生长因子受体的表达与肿瘤侵袭的关系
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    Inhibition of Proliferation,Anti-invasion and Induction of Apoptosis in Bladder Cancer Cells by 10-HCPT
    10-羟基喜树碱对人膀胱癌细胞增殖、侵袭的抑制作用及诱导凋亡的研究
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  invasion
Based on the result and extensive risk communications, combined with the management experience of the Beijing Forest Protection Station, the authors proposed some effective control measures to prevent the invasion of the three pests into Beijing.
      
Impact of the invasion of pinewood nematode and the following different removal disturbance intensities on the plant diversity o
      
Alien plants, along with their ecological invasion and negative impacts on indigenous species diversity and ecosystems, are one of the major topics of current ecological research.
      
It is a cytosolic protein that protects cells from the adventitious invasion of pancreatic-type ribonuclease.
      
Successful immunotherapy of tumors requires understanding of the natural relationship between the immune system and tumor in the status of differentiation, invasion and maturation.
      
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  invasiveness
LOH of the FHIT gene in GC was related to depth invasiveness, and its frequency in GC where serosa was penetrated was significantly higher than that in GC without serosa penetration (73.5% vs 37.5%, P >amp;lt; 0.05).
      
There was no correlation of the E2 status and MMP-9 expression with clinical/morphological characteristics of the tumors: size, local invasiveness, metastasizing into regional lymph nodes, and level of differentiation.
      
Overexpression of BCSG1 in cancer cells led to significant increase in cell proliferation, motility and invasiveness, and metastasis.
      
Both E-Cadherin and β-Catenin were proved respectively with tumor suppressor effect against invasiveness and metastasis.
      
Therefore, our study suggests that the age-associated increase in AGEs might be one potential host factor responsible for the less invasiveness of tumours at very advanced age.
      
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Malignant rhabdoid tumor of thekidney is rare.This paper reports 2cases proved pathologically.It is hig-hly malignant with distinctive clinicalcomputed tomographic and pathologicfeatures.The CT characteristic findi-ngs included extensive destruction ofrenal parenchyma and forming a mai-nly cystic lesion with central soft-masslike“melting ice”.Subcapsular fluidcollection and invasive nodules wereobserved.In addition,the renal pelviswas also involved frequently.

肾恶性横纹肌样瘤是一罕见的高度恶性肿瘤,临床、CT和病理表现均有特殊之处。本文报告2例,均经病理诊断。作者认为肾脏广泛破坏,形成以囊性变为主并存“溶冰状”改变的软组织肿块,累及肾盂、伴肾包膜侵袭结节和肾包膜下积液是本病的CT特点。

Using monoclonal anti-type Ⅳ collagen, laminin andpolyclonal anti-fibronectin antibod-ies,the basement membrane(BM ) of sixty five cases of bladder transitional cell carcinomahad been studied with immunohistochemical methods.It was shown that all the three anti-bodies could reveal BM around the cancer nests.The results were simuarbut not identical,indicating their different distrbutions. Most of the invasive carcinomas had certain degree ofdegradation ,even absence of BM.It was found that patients having tumors...

Using monoclonal anti-type Ⅳ collagen, laminin andpolyclonal anti-fibronectin antibod-ies,the basement membrane(BM ) of sixty five cases of bladder transitional cell carcinomahad been studied with immunohistochemical methods.It was shown that all the three anti-bodies could reveal BM around the cancer nests.The results were simuarbut not identical,indicating their different distrbutions. Most of the invasive carcinomas had certain degree ofdegradation ,even absence of BM.It was found that patients having tumors with continuouslinear BM had significantly higher survival rate(P<0. 05 ) ,their tumors being lessinvasiveand their tumor cells more highly differentiated than those with interrupted or absent BM. Itis suggested that the completeness of BM in biadder transitional cell carcinomas can be usedas a good parameter in clinical practice for the judgement of invasiveness,metastasis of tu-mor and prognosis of the patients.

采用抗Ⅳ型胶原、层粘连蛋白和纤维连接蛋白三种抗体研究65例膀胱移行细胞癌基底膜(BM)。发现三种抗体均能很好地显示肿瘤组织周围的BM,其结果大致相同,但不完全一样,说明三者在BM中的分布不完全一致。多数浸润癌的BM均有一定程度的破坏,甚至完全缺如。同时还发现BM较完整的病人生存率高、肿瘤侵袭力弱、肿瘤的分化程度相对较高。提示BM的完整性可作为临床判断肿瘤浸润、转移和病人预后的一个重要指标。

An immunohistochemical technique was used to study the invasion and metastasis in 32 specimens of bladder cancer with 10 normal cases served as controls. The loss of the epithelial basement membrane and the smooth muscle bunch membrane, the lower expression of their Fn were observed in 14 samples of invading bladder cancer. Some bloood vesseles were invaded by cancer cells in 2 cases of T4 invading cancer,the loss of blood vesselar basement membrane and the lower expression of it Fn were observed in this position....

An immunohistochemical technique was used to study the invasion and metastasis in 32 specimens of bladder cancer with 10 normal cases served as controls. The loss of the epithelial basement membrane and the smooth muscle bunch membrane, the lower expression of their Fn were observed in 14 samples of invading bladder cancer. Some bloood vesseles were invaded by cancer cells in 2 cases of T4 invading cancer,the loss of blood vesselar basement membrane and the lower expression of it Fn were observed in this position. It is suggested that the basement membrane and the expression of it Fn might be considered as markers for invasion,metastasis and prognosis in bladder cancer.

以纤维连接蛋白(Fn)为标记物,应用免疫组化技术对32例膀胱癌及10例正常膀胱组织中上皮基底膜、血管基底膜及平滑肌束膜进行检测.结果显示,正常膀胱组织中,上皮及血管基底膜、平滑肌束膜连续性完整.浸润型膀胱癌,上皮基底膜和平滑肌束膜中断、缺失普遍存在,相应部位癌细胞侵袭,Fn成份表达率下降;浅表型膀胱癌改变不明显,两者间有显著性差异.在2例T_4期膀胱癌中发现癌细胞侵袭小血管,相应部位基底膜及Fn成份缺失.提示,基底膜及平滑肌束膜受损程度,其Fn成份表达程度可作为评估膀胱癌侵袭,转移及预后判定的客观指标.

 
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