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前列腺癌细胞株     
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  prostate cancer cell line
     An Experimental Study of Pro-apoptosis Effect of Mifepristone on Androgen-dependent Prostate Cancer Cell Line LNCaPC_4 and Androgen-independent Prostate Cancer Cell Line LNCaPC_(4-2)、PC_3 in Vitro
     米非司酮促进雄激素依赖型前列腺癌细胞株LNCaPC_4及雄激素非依赖型前列腺癌细胞株LNCaPC_(4-2)、PC_3凋亡的体外实验研究
短句来源
     Methods Androgen-dependent prostate cancer cell line LNcap-FCG were cultured in vitro and testosterone was added to the medium at different concentrations of 10-10, 10-9, 10-8, 10-7, 10-6, 10-5 mol/L.
     方法体外培养前列腺癌细胞株LNcap-FCG,加入睾酮,使各组终浓度为10-10、10-9、10-8、10-7、10-6、10-5mol/L。
短句来源
     Effects of Omi/HtrA2 on Expression of Anti-apoptotic Protein PED/PEA-15 and Apoptosis of Prostate Cancer Cell Line PC-3
     Omi/HtrA2对前列腺癌细胞株PED/PEA-15表达及PC-3细胞凋亡的影响
短句来源
     Role of ERβ on Proliferation and Apoptosis in Hormone Independent Prostate Cancer Cell Line PC-3 and PC-3M
     ERβ对激素非依赖性前列腺癌细胞株PC-3和PC-3M增殖和凋亡的影响
短句来源
     Objective To investigate the effects of all-trans-retinoic acid(ATRA) on the proliferation and the expression of bcl-2 and bax in human androgen-independent prostate cancer cell line PC-3.Methods Human prostate cancercell line PC-3 was cultured in medium containing in different of ATRA concentrations.
     目的探讨全反式维甲酸(all-trans-retinoic acid, ATRA)对人雄激素非依赖性前列腺癌细胞株PC-3增殖的抑制作用及其bcl-2和bax表达的影响。
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  prostate cancer cell lines
     Expressions of vascular endothelial growth factor(VEGF) and its receptor (KDR),basic fibroblast growth factor(bFGF) and its receptor (FGFR2) in human prostate cancer cell lines
     前列腺癌细胞株VEGF及其受体KDR,bFGF及其受体FGFR2的表达及意义
短句来源
     Results: The mRNA levels of RECK in DU-145,LNCap and PC-3 cells were obviously lower than those in the benign prostate hyperplasia cell strain BPH-1(P<0.01),while the levels of MMP-2 and MMP-9 mRNA were higher in prostate cancer cell lines(P<0.01).
     应用Western印迹法检测不同前列腺细胞株中RECK蛋白的表达。 结果:前列腺癌细胞株DU-145、LNCap以及PC-3中RECKmRNA的表达较良性前列腺增生细胞株BPH-1中明显降低(P<0.01),MMP-2、MMP-9 mRNA表达则明显升高(P<0.01)。
短句来源
     Results:Hypermethylation was found in 33% of prostate cancer cell lines(2/6)and correlated well with decreased E-cad mRNA levels in these cell lines.
     结果 :有 33% (2 /6)的前列腺癌细胞株发生甲基化现象 ,相应的细胞株中 E- cad m RNA水平降低。
短句来源
     Expression of major heat shock protein 70 in human prostate cancer cell lines PC-3m and LNCaP and its implication
     热休克蛋白70在人前列腺癌细胞株PC-3m和LNCaP中的表达及其意义
短句来源
     Results: XlAP gene was not expressed in normal prostate tissues, but highly expressed in prostate cancer cell lines PC-3,DU-145,LNCaP.
     结果 :XIAP基因在前列腺癌组织和前列腺癌细胞株PC 3,DU 14 5 ,LNCaP细胞高表达 ,正常前列腺组织无表达。
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  prostatic cancer cell lines
     Objective To study the effect of hyperthermia on growth of human prostatic cancer cell lines PC-3m and LNCaP in vitro.
     目的 探讨高温对人前列腺癌细胞株PC - 3m和LNCaP生长的影响。
短句来源
  prostate carcinoma cell
     Objective To observe the change characteristics of TGF-β 1 mRNA expression in human prostate carcinoma cell strain (PC-3) in vitro.
     目的 观察人前列腺癌细胞株 (PC- 3) TGF-β1 m RNA表达变化特点。
短句来源
     Methods After treatment of 1×10 -9 ? mol/L for 24 h, expression of cell cycle regulation molecules including CDK2, CDK4, CDK6 and p27 kipl in human prostate carcinoma cell line LNCaP and PC 3 was detected by using immunoprecipitation and Western blot analysis after 0, 8 and 24 h of withdrawal of androgen.
     方法 在人前列腺癌细胞株LNCaP和PC 3中 ,先加 1× 10 -9mol/L双氢睾酮 (DHT)维持培养 2 4h后分别于去除DTH 0、8和 2 4h行免疫沉淀和WesternBlot分析检测细胞周期素依赖激酶CDK 2、CDK4、CDK6和p2 7kip1的表达。
短句来源
     Methods: Human prostate carcinoma cell lines(LNCaP and C4-2B) with different metastatic potentials were selected.
     方法:应用免疫组织化学SABC法,研究IV型胶原酶在不同转移潜能的前列腺癌细胞株LNCaP、C4-2B中表达变化。
短句来源
     Methods The cell biological changes of prostate carcinoma cell strain (PC-3) were observed by flow cytomtry technique (FCM),trypan blue dyeing count method and 3H-TdR method.
     方法 应用流式细胞术(FCM)、台盼蓝染色计数法和3 H -TdR掺入法观察NaPA对人前列腺癌细胞株的细胞周期动力学变化的影响。
短句来源
     Results The mRNA level of the PECK gene on the prostate carcinoma cell strains(DU-45,LNCap and PC-3) was lower than that on the benign prostate hyperplasia cell strain BPH-1,while the matrix metalloproteinase-2 (MMP-2) level was higher.
     应用Westernblot检测不同前列腺细胞株中RECK基因的表达。 结果前列腺癌细胞株DU-145、LNCap以及PC-3中RECKmRNA的表达较良性前列腺增生细胞株BPH-1中明显降低(P<0.01),MMP-2mRNA表达则明显升高。
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  prostate cancer cell line
We identified ARA70, a coactivator of the androgen receptor and PPARγ, as a ligand-enhanced coactivator of PPARα in the prostate cancer cell line DU145.
      
LNCaP is an androgen sensitive prostate cancer cell line, DU-145 and PC-3 are androgen resistant, and TSU-Pr1 is uncharacterized.
      
Role of superoxide anion on the proliferation and c-Ha-ras or p53 expression in prostate cancer cell line PC3
      
The purpose of this study was to investigate the role of superoxide anion (O-.2) in the regulation of p53 or c-Ha-ras expression and proliferation in the prostate cancer cell line PC3.
      
Characterization of chromosome 8 aberrations in the prostate cancer cell line LNCaP-FGC and sublines
      
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  prostate cancer cell lines
It was proved that there was a putative predisposing gene for prostate cancer in this region, and that analogs of GGPP can inhibit the geranylgeranylation of p21rap protein in PC-3 prostate cancer cell lines.
      
Following incubation, the cultured cells containing immature DCs were concentrated and transfected with tumour mRNA from human prostate cancer cell lines employing a highly efficient electroporation procedure.
      
Screening of differently expressed genes in human prostate cancer cell lines with different metastasis potentials
      
It was concluded that two subtractive libraries of human prostate cancer cell lines with different metastasis potentials were constructed successfully.
      
By Northern blot analysis, this gene product was not detectable in LNCaP, DU 145, or PC-3 prostate cancer cell lines, although it was readily observed in RNA isolated from total prostate and from dissected central and peripheral regions of prostate.
      
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  prostatic cancer cell lines
Effects of BFA (30?ng/ml) were examined on the growth of three human prostatic cancer cell lines, PC-3, DU-145, and LNCaP cells.
      
Lectin-induced alterations on the proliferation of three human prostatic cancer cell lines
      
Three prostatic cancer cell lines (PC3, DU145 and TSU-Pr1), one primary prostatic cancer and four benign prostatic hyperplasias (BPH) were studied.
      
Moreover, we identify SHP-1 in human prostatic cancer cell lines as well as in human prostate and prostate cancer.
      
Prostatic cancer cell lines were used to elucidate the mechanisms by which NAO exerts it anticarcinogenic effects.
      
  prostate carcinoma cell
Normal genital skin fibroblasts (GSF) and the human prostate carcinoma cell line LNCaP have been used widely as cell culture models of genital origin to study androgen receptor (AR) signaling.
      
Antiproliferative effect of interferons on human prostate carcinoma cell lines
      
The effect of purified human fibroblast beta-interferon (B-IFN) and recombinant alpha-2b-interferon (A-IFN) on cell proliferation was investigated in two human prostate carcinoma cell lines, named PC-3 and DU-145.
      
Effects of selected chemotherapeutic agents on PCNA expression in prostate carcinoma cell lines
      
Bivariate flow cytometric analysis of proliferating cell nuclear antigen (PCNA) was performed on prostate carcinoma cell lines (PC-3, DU-145).
      
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