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抗菌素
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  antibiotic
     STUDIES ON THE AGRICULTURAL ANTIBIOTICS 5102 Ⅲ. Isolation and characterization of antibiotic 5102-1-Ⅲ
     农用抗菌素5102的研究——Ⅲ、5102-1号抗菌素第Ⅲ组份的分离及鉴别
短句来源
     Methods When absolute neutrophil count(ANC) fell below 0.5×10 9/L,the patients were isolated in a laminar airflow unit or strictly sterilized room,and were given granulocyte colony stimulating factor(G CSF) and antibiotic until white ANC rose over 2.0×10 9/L.
     方法 化疗后当绝对粒细胞计数 (ANC)≤ 0 .5× 10 9/L时 ,对患者采取保护性隔离 ,应用粒细胞刺激因子 (G CSF)、抗菌素等直至血象恢复至ANC≥ 2 .0× 10 9/L。
短句来源
     4 Aminoglycoside antibiotic G418 can inhibit the growth of P. membranefaciens.
     4、 氨基糖甙类抗菌素G418能够抑制P.
短句来源
     Clinical Application of Antibiotic Mechanism of Bacterial Drug Resistance and New Drugs
     抗生素临床应用、细菌耐药机制及其新药——“β-内酰胺类抗菌素临床应用及研究进展”研讨会纪要
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     THE STRUCTURE OF A NEW ANTIBIOTIC 10676
     新抗菌素10676化学结构研究
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  antibiotics
     ~1H AND ~(13)C NMR STUDY OF SEVERAL ANTIBIOTICS
     几种抗菌素的~1H 和~(13)C NMR 谱的研究
短句来源
     STUDIES ON THE AGRICULTURAL ANTIBIOTICS 5102 Ⅲ. Isolation and characterization of antibiotic 5102-1-Ⅲ
     农用抗菌素5102的研究——Ⅲ、5102-1号抗菌素第Ⅲ组份的分离及鉴别
短句来源
     The bacilli sensitive rate to antibiotics was as high as 71.2% to Ceftazidime,70.0% to Ofloxacin,62.1% to Cefatriaxone,60.6% to cefoperazone or cefoperazone,60.0% to cefazolin,53.1% to Piperacillin respectively.
     药物敏感试验提示革兰阴性杆菌对抗菌素的敏感性依次为头孢他啶71.2%、氧氟沙星70.0%、头孢曲松62.1%、头孢噻肟60.6%、头孢哌酮60.6%、头孢唑啉60.0%、哌拉西林53.1%。
短句来源
     The resistance of NFB to other antibiotics was Gentamycin 30.0%, Ciproflozacin 42.9%, Ceftazidime 45.0%, Aztreonam 45.3%, Sulfamethoxazole-Trimethoprin 88.9%, Tetracycline 93.1% and Ampicillin 95.5% respectively.
     其余的抗菌素依次为 :庆大霉素 (GEN )30 .0 %、环丙沙星 (CIP) 4 2 .9%、头孢他啶 (CAZ) 4 5 .1%、氨曲南 (ATZ) 4 5 .3%、复方新诺明 (SXT)88.9%、四环素 (TET) 93.1%、氨苄青霉素 (AMP) 95 .5 %。
短句来源
     The two isolates GX_97 and GX_98_1 also showed a closer pattern of antibiotics resistance with reference strain C195_11.
     抗菌素敏感试验也显示GX_97、GX_98_1和参考菌株的药敏谱更加相似
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  “抗菌素”译为未确定词的双语例句
     (2) Drug resistance rates were Ciprofloxacin 39.8%,Roxithromycin 32.8%,Azithromycin 32.8%,Clarithromycin29.7%.
     (2)环丙沙星、罗红霉素、阿奇霉素、克拉霉素是耐药率最高的四种抗菌素,耐药率依次为39.8%、32.8%、32.8%、29.7%。
短句来源
     Escherichia coli was sensitive to imipenem(97.2%),amikacin(87.4%),ceftazidime (81.3%),Cefuroxime (81.1%),and cefotaxime (80.3%). The sensitivity to quinolones,tetracycline and ampicillin were43%,16.5%,and20.7%,respectively.
     492株大肠埃希氏菌对亚胺培南、阿米卡星和头孢类抗菌素敏感率依次为97.2%、、87.4%、81.3%,对喹诺酮类、四环素和氨苄西林敏感率依次为43%、16.5%、20.7%;
短句来源
     And the optical bacteriophage is 500mg/L Cef.
     通过抑菌实验,确定了合适的抗菌素及其浓度(即500mg/L Cef)。
短句来源
     Results (1) Drug sensitivity rates to mycoplasma were Doxycyclina Hyclate 96.1%,Minocycline Hydrochloride 94.5%,Josamycin 93.0%. Sparfloxacin 71.1%.
     结果(1)强力霉素、美满霉素、交沙霉素、司帕沙星最为敏感的四种抗菌素,药敏率依次为96.1%、94.5%、93.0%、71.1%。
短句来源
     the proportion of usage for anti- bacterial drugs in prescription was 5 8.97% ,while hormone drugs was 16 .83% ;
     抗菌素类药物处方使用率 5 8.97% ,激素类药物处方使用率 16 .83% ;
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  antibiotic
An antibiotic producing strain Streptomyces violaceusniger was isolated from soil sample, characterized and studied for antibacterial and antifungal activity profile.
      
The activity profiles of the intracellular and extracellular crude extracts showed that the antibiotic producing culture produces two or more compounds, one being intracellular (antifungal), other being extracellular (antibacterial).
      
Production medium was optimized for antibiotic production.
      
Brefeldin A (BFA; C16H24O4, MW 280), a naturally occurring macrolide, exhibits diverse biological activities, such as antibiotic, antiviral, cytostatic, antimitotic, and antitumor effects.
      
Obtaining a high-activity strain capable of producing the antistaphylococcal antibiotic batumin
      
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  antibiotics
cyclotriazadisulfonamides), viral envelope gp120-binding agents such as plant lectins and glycopeptide antibiotics, HIV integrase inhibitors such as the pyranodipyrimidine V-165, and two new classes of compounds (i.e.
      
Study on the interaction of aminoglycoside antibiotics with Titan Yellow by spectrophotometric method and their analytical appli
      
In a weak acidic medium, the reaction of some aminoglycoside antibiotics (AGs) such as kanamycin sulfate (KANA), gentamycin sulfate (GEN), and tobramycin sulfate (TOB) with acid thiazolyl bisazo dye Titan Yellow (TY) can result in the fading of TY.
      
This method has high sensitivity and can be applied to the determination of commercial aminoglycoside antibiotics and serum samples with satisfactory results.
      
In order to identify the function of the extracts, the activity of antibiotics, antioxidation, and immunity test were carried out against these functions.
      
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Studies on three types of antifungal antibiotics produced by representative Actinomycetes has been described. Three morphologically distinct groups classified as series white, yellow and brown were subjected to chemical examinations for their characteristics. All these groups of Actinomycetes were primarily antifungal against a variety of test fungi. They are taxonomically unrelated organisms possessing the ability to produce different forms of antifungal substances. By means of solvent extraction, three antibiotics...

Studies on three types of antifungal antibiotics produced by representative Actinomycetes has been described. Three morphologically distinct groups classified as series white, yellow and brown were subjected to chemical examinations for their characteristics. All these groups of Actinomycetes were primarily antifungal against a variety of test fungi. They are taxonomically unrelated organisms possessing the ability to produce different forms of antifungal substances. By means of solvent extraction, three antibiotics designated as antibiotic A-94, A-113 and A-262 were successively obtained in forms of crystalline powder or amorphous solid. The characterized ultraviolet and infrared absorption spectra of these antibiotics indicated the presence of chemically different polyene structures, for example, antibiotic A-94 was classified as conjugated tetraene, and both antibiotic A-113 and A-262 as conjugated heptaene. On the basis of comparison of chemical reactions with the known polyene antibiotics recorded in literatures, it is suggested that, antibiotic A-94 is identical to fungicidin, and antibiotic A-113 and A-262 should be regarded as two new members of the heptaene group, based upon the fact that although both gave positive Molisch reaction as does amphotericin B, they differed essentially from amphotericin B by specific rotation in several solvents. However, with the aid of analysis of functional groups it is possible to differentiate antibiotic A-113 from antibiotic A-262 according to the absence of N-methyl group in the molecule of antibiotic A-262. The biological spectra of these antibiotics when tested upon representative organisms showed that both the heptaene antibiotic A-113 and A-262 were active in vitro against influenza virus PR_8 and protozoa such as trichomonas vaginalis, while the tetraene antibiotic A-94 was found to have weak effect against influenza virus and no effect on protozoa. All these three polyene antibiotics were strongly effective-against pathogenic and saprophtic candida and bear yeast, but apparently have no inhibitory action against different forms of bacteria as well as Ehrlich ascites tumour cell.

对中国南方土壤最常发現之三种类型放綫菌的三种代表抗菌素,从化学与物理性貭与文献所报告者作了比较,发现抗菌素A-94与制霉菌素(Fungicidine,Nystatin)为同一化合物。其他二个抗菌素A-113与A-262之研究推论为属于七烯类之新抗菌素,这两个抗菌素除抗酵母菌外并具有抗原虫、流感病毒之生物性质。

The amino groups and the lipophilic side chain in polymyxin B have been reported to be responsible for the action against Pseudomonas aeruginosa. Since phenazine derivatives usually exhibited potent bacteriostatic action, we have accordingly prepared a number of phenazinium salts carrying amino groups and an N-alkyl side chain for screening purposes. However, antibacterial tests showed that none of the compounds so prepared was active.

据前人报告多粘菌素B具有抗绿脓杆菌的作用,是与该抗菌素的分子内含有五个游离氨基及脂溶性侧链有关的;另外有些9,10-二氮杂蒽类衍生物对不同株绿脓杆菌亦有抗菌作用.因此合成了一些取代氨基N-烷基-9,10-二氮杂蒽季胺盐,进行抗绿脓杆菌筛选,结果抗菌作用不明显.

Thirteen adult guinea-pigs were divided into 3 groups:2 as normal controls;6 and 5 being treated with streptomycin sulphate 200 and 400mg per kilo body weight res- pectively for 21—60 days.The vestibular and auditory functions were tested.Their brains were prepared for Bielschowsky and Nissl sections.Microscopic examination re- vealed the following facts. Vascular disturbances prevail in the nervous system.The blood vessels are crumpled with concommittent perivascular edema.The adjacent nervous tissue shows...

Thirteen adult guinea-pigs were divided into 3 groups:2 as normal controls;6 and 5 being treated with streptomycin sulphate 200 and 400mg per kilo body weight res- pectively for 21—60 days.The vestibular and auditory functions were tested.Their brains were prepared for Bielschowsky and Nissl sections.Microscopic examination re- vealed the following facts. Vascular disturbances prevail in the nervous system.The blood vessels are crumpled with concommittent perivascular edema.The adjacent nervous tissue shows ischemic softening and the nerve fibres become demyelinated. The intoxicated nerve cells are generally dehydrated and shrunken often with eccen- tricity of nuclei and chromophilic lumps.Gliosis and neurophagosis are common. The vestibular and cochlear systems of the eighth or stato-acoustic nerve exhibit intoxicative changes in the 2 groups of animals.On the peripheral as well as the central side,the degeneration of the vestibular structures supercedes that of the cochlear system. The site and nature of the intoxication are much alike in the light and heavy-dose groups,yet the latter shows a higher severity. The degenerative alterations appear simultaneously in the perpheral and central struc- tures.A question of primacy in intoxication—peripheral or central—is not existent. There is a chain of structures on the peripheral and central sides of the stato-acoustic system;their degeneration does not proceed along the conduction path,nor the degree of intoxication varies with their relative positions on the conduction scale.The peri- pheral and central units get intoxicated independently. Besides the stato-acoustic structures streptomycin afflicts other sensory(e.g.trige- minal) and motor systems,the viscero-motor in particular.Streptomycin intoxication is general in nature,yet some structures are especially sensitive to it. The relative vulnerability to streptomycin of the nervous structures is apparently conditioned by their chemical constitution. Streptomycin injuries higher brain parts which are mainly motor,especially viscero- motor.The diencephalic viscero-motor nuclei,the striate complex and the visceral cor- tex are excessively disintegrated.The extensive intoxicative manifestations have a neurological basis. The toxin of streptomycin affects the entire nervous system and hence the whole bodily mechanisms.Its medical application calls for a meticulous consideration with respect to the patient's sensitivity to the antibiotic,the size of the dose and the length of the therapeutic course.

十三个成长的豚鼠分为三粗,2个作正常对照,此外6个和5个每日分别注射链霉秦硫酸盐,一公斤体重200和400毫克,共经21至60天。未了,豚鼠都经过平衡和听觉的测验。各脑分别染制Nissl和Bielschowsky切片。显微镜的检查得到以下的结果。神经系中普见血管的病变。血管塌陷,管外间质水肿。邻近的神经组织失血软化。神经纤维表现髓鞘溶解。中毒的神经细胞脱水萎缩,常见胞核偏位,染色质偏聚、结块。也时有神经胶质增生和神经吞噬现象。二组豚鼠在位听神经的前庭系和耳蜗系都有中毒的征象。在周缘部和中枢部,前庭系各极结构的病变,与耳蜗系相较,更为严重。在注射轻剂和重剂的二组豚鼠,神经系中毒的部位和性质是相似的,但重剂组的病变程度较高。在位听系,中毒的病变同时见于周缘部和中枢部。中毒的第一性的问题——在周缘, 抑在中枢——是不存在的。周缘和中枢各有一系结构,病变的表现不沿神经传导的路线;病变的轻重也不随路线上地位的高低。周缘和中枢的各项结构是各自中毒的。链霉素不仅毒害位听神经一系,而更损伤其它感觉系(如三叉神经系)和运动系——特是内脏运动系——的结构。链霉素中毒是一般性的,但有些结构特易感受它的毒害。在各级结构中,神经细胞的...

十三个成长的豚鼠分为三粗,2个作正常对照,此外6个和5个每日分别注射链霉秦硫酸盐,一公斤体重200和400毫克,共经21至60天。未了,豚鼠都经过平衡和听觉的测验。各脑分别染制Nissl和Bielschowsky切片。显微镜的检查得到以下的结果。神经系中普见血管的病变。血管塌陷,管外间质水肿。邻近的神经组织失血软化。神经纤维表现髓鞘溶解。中毒的神经细胞脱水萎缩,常见胞核偏位,染色质偏聚、结块。也时有神经胶质增生和神经吞噬现象。二组豚鼠在位听神经的前庭系和耳蜗系都有中毒的征象。在周缘部和中枢部,前庭系各极结构的病变,与耳蜗系相较,更为严重。在注射轻剂和重剂的二组豚鼠,神经系中毒的部位和性质是相似的,但重剂组的病变程度较高。在位听系,中毒的病变同时见于周缘部和中枢部。中毒的第一性的问题——在周缘, 抑在中枢——是不存在的。周缘和中枢各有一系结构,病变的表现不沿神经传导的路线;病变的轻重也不随路线上地位的高低。周缘和中枢的各项结构是各自中毒的。链霉素不仅毒害位听神经一系,而更损伤其它感觉系(如三叉神经系)和运动系——特是内脏运动系——的结构。链霉素中毒是一般性的,但有些结构特易感受它的毒害。在各级结构中,神经细胞的化学合成决定它们反应链霉素的灵钝和轻重。链霉素伤害高级的脑部,这多属运动性,特是内脏运动性。间脑的内脏性核团、纹状体簇和内脏性皮质中毒特别剧烈。链霉素中毒症状广泛,这是有神经基础的。链霉素的毒质伤害全神经系,也影响全身;为医疗使用这个抗菌素,关于患者对此药的敏感,剂量和疗程是要慎重考虑的。

 
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