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   浸润癌组织 在 妇产科学 分类中 的翻译结果: 查询用时:0.068秒
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浸润癌组织
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  invasive carcinoma
    Methods: Using streptavidin-biotin peroxidase(SP) method,the expression of Survivin,Bcl-2, and P53 protein in tissue of 10 cases of normal controls, 18 cases of atypical hyperplasia,21 cases of carcinoma in situ,and 69 cases of cervical invasive carcinoma were examined.
    方法:采用SP免疫组织化学方法, 检测10例正常宫颈组织,18例宫颈不典型增生组织,21例宫颈原位癌组织,69例宫颈浸润癌组织中Survivin、bcl -2 及P53蛋白的表达。
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    Results P 33ING1 positive expression in normal cervical tissue is 100%(10/10); the expression in carcinoma-in-stiu and cervical invasive carcinoma tissues is obviously lower,57.1% (11/21) and 59.4%(41/69) than that in normal cervical tissues. The experssion of P 33ING1 was related to that of P_ 53 in cervical carcinoma.
    结果 对照组中P33ING1均阳性表达100%(10/10)而宫颈原位癌和宫颈浸润癌组织中表达分别为57.1%(11/21)和59.4%(41/69),明显下降,与对照组之间差异显著P33ING1和P53的表达有相关性。
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    (2) There was no significant difference between the carcinoma in situ and invasive carcinoma (P>0.05), but in poor differentiation cervical carcinoma, p185 protein was highly expressed (56.8%). The expressions of p185 proteins was related to clinical stage (P<0.05).
    (2)p185蛋白在原位癌组织和浸润癌组织中的表达差异无统计学意义(P>0.05),但低分化鳞癌中p185蛋白表达与原位癌比较,差异具有统计学意义(P<0.01),II期和III期宫颈癌患者组织中的p185蛋白表达明显高于0期和I期的患者(P<0.05);
短句来源
    Methods: The expression of P 33ING1 , P53, and Bcl-2 in 10 cases of normal cervical tissue, 18 cases of atypical hyperplasia, 21 cases of carcinoma in situ, and 69 cases of cervical invasive carcinoma tissue were detected using immunohistochemical method.
    方法:应用免疫组织化学方法分别检测正常宫颈组织(10例),宫颈不典型增生组织(18例),宫颈原位癌组织(21例)以及宫颈浸润癌组织(69例)中P33ING1,P53和Bcl-2的表达。
短句来源
    In normal cervical tissue, atypical hyperplasia tissue, carcinoma in situ, and cervical invasive carcinoma tissue, the expression rates of P53 were 0,0,28.6% and 59.4%, respectively, and those of Bcl-2 were 0,44.4%,57.1%, and 63.8%.
    宫颈浸润癌组织中为59.4%(41/69)。 P33ING1在原位癌、浸润癌组织中的表达明显低于正常宫颈组织和不典型增生组织(P<0.01)。
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  “浸润癌组织”译为未确定词的双语例句
    Methods:Immunohistochemical method was used to detect the expression of P16INK4A in 30 cases of normal cervical tissues, 23 cases of CINⅠ,26 cases of CINⅡ, 31 cases of CINⅢ, and 22 cases of invasive squamous cell carcinomas of cervix(ISCC).
    方法:应用免疫组织化学方法检测30例正常宫颈组织、23例宫颈上皮内瘤变Ⅰ级(CINⅠ)、26例CINⅡ、31例CINⅢ和22例浸润癌组织中P16INK4A蛋白的表达;
短句来源
    METHODS: The expression of P16INK4A and PTEN in 30 specimens of normal cervical tissues, 11 specimens of cancer in situ (CIS), and 24 specimens of invasive cervical carcinoma (ICC) was detected by SP immunohistochemistry;
    方法:应用免疫组织化学方法检测P16INK4A蛋白和PTEN蛋白在30例正常宫颈组织、11例原位癌、24例宫颈浸润癌组织中的表达。
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    Expression of CD44V6、PCNA、CⅣ in Cervical Invasion Cancer and Metastasis Potentiality
    宫颈浸润癌组织中CD44V6、PCNA、CⅣ表达与转移潜能的关系研究
短句来源
    P16 protein overexpressioned in CIS and CC, there was low or negative expression of P16 in normal cervical tissue (4)There was strong relationship between p16mRNA expression and HPV16/18E7mRNA expression (r=0. 81322) (P<0. 05) ;
    HPV16/18E7阳性组p16mRNA的表达明显高于阴性组,其差别有统计学意义(P<0.05); P16蛋白在宫颈原位癌和浸润癌组织中呈现过表达,在正常组织中为阴性表达或弱表达;
短句来源
    Methods: The expression and distribution of MMP-7 and TIMP-1 proteins are detected by immunohistochemical technique in 53 cases of cervical carcinoma tissue, 9 cases of CIN and 10 cases of normal cervices tissue coming from operation specimen excised because of myoma of uterus.
    研究方法:本研究采用免疫组化SP法对53例宫颈浸润癌组织,9例CIN,10例因子宫肌瘤而行子宫切除的正常宫颈组织标本进行MMP-7及TIMP-1蛋白表达的检测。
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  invasive carcinoma
Molecular studies have revealed that PanIN-2 and PanIN-3 lesions represent a distinct step toward invasive carcinoma.
      
PIN has a high predictive value as a marker for adenocarcinoma, and its identification warrants repeat biopsy for concurrent or subsequent invasive carcinoma.
      
Barrett's esophagus describes metaplastic changes from squamous mucosa to specialized columnar epithelium that can progress from low-grade dysplasia to high-grade dysplasia and even invasive carcinoma.
      
Although these factors may determine different treatment strategies, surgery remains the mainstay of therapy due to the favorable survival rate if the disease is diagnosed and treated prior to the development of invasive carcinoma.
      
Epithelial atypia was histologically classified into five groups: normal epithelium; papillary hyperplasia without atypia; atypical hyperplasia; carcinomain situ; and invasive carcinoma.
      
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In normal cells, p53 protei n is virtually unndetectable by immunohistochemical mathcds. Mutation of p53 gene results in overexpression of the protein and thus levels of p53 detectable by immunohistochemical methods. We studied the expression of p53 protein in humanCervical carcinoma (39 cases )paraffin embedded tissue sections by immunohistochemical methods.Of these cervical carcinorna specimens overexpression of P53 protein was showed in 19 cases (48.7 % )and was a higher percentage in low differentiation...

In normal cells, p53 protei n is virtually unndetectable by immunohistochemical mathcds. Mutation of p53 gene results in overexpression of the protein and thus levels of p53 detectable by immunohistochemical methods. We studied the expression of p53 protein in humanCervical carcinoma (39 cases )paraffin embedded tissue sections by immunohistochemical methods.Of these cervical carcinorna specimens overexpression of P53 protein was showed in 19 cases (48.7 % )and was a higher percentage in low differentiation rodent cancer (75 % ) than in high differentiation rodent cancer (42. 9 % ). These results suggested that overexpression of p53 often occuredin cervical carcinoma and that the percentage of overexpression of p53 Was tight relative to thedifferentiation degree of human cervical carcinoma.

利用免疫组织化学方法,对39例子宫颈癌(5例原位癌。3例早期浸润癌,31例浸润癌)组织石腊包理标本进行了P53表达的检测,结果发现39例子宫颈癌标本中.19例有P53的高表达(48.7%)(2例原位癌、且例早期浸润癌、16例浸润癌)。还发现P53高表达阳性率在分化较好的浸润癌相对较低(42.9%),在分化较差的浸润癌相对较高(75%)。这些结果表明P53的高表达在子宫颈癌的发生中是一个比较常见的基因改变,P53高表达的阳性率与子宫颈癌的分化程度有关。

Objective To study expression of CD44V6、PCNA、CⅣ in the cervical invasion cancer and their metastasis potentiality.Methods Expression of CD44V6、PCNA、CⅣ in 104 case of cervical cancer were detected by immunohistochemistry S P method.Results In normal cervical tissues,there were not expression of CD44V6.In pelvie lympy node metastasis groups,CD44V6 was expressed with a high positive rate of 81.57%.In the group without pelvie lympy node metastasis,a lower positive rate of 36.36% was found.It was significant...

Objective To study expression of CD44V6、PCNA、CⅣ in the cervical invasion cancer and their metastasis potentiality.Methods Expression of CD44V6、PCNA、CⅣ in 104 case of cervical cancer were detected by immunohistochemistry S P method.Results In normal cervical tissues,there were not expression of CD44V6.In pelvie lympy node metastasis groups,CD44V6 was expressed with a high positive rate of 81.57%.In the group without pelvie lympy node metastasis,a lower positive rate of 36.36% was found.It was significant different between the two groups.In CD44V6 positive groups,the expression of PCNA was high and CⅣ was low,compared with the CD44V6 negative group,it was singificant defferent between the two above groups.Conlusion CD44V6 expression may associate with tumor metastasis.

目的 探讨CD44V 6、PCNA、CⅣ在宫颈浸润癌组织中的表达与转移潜能的关系。方法 采用免疫组织化学S P法检测 10 4例宫颈浸润癌组织中的CD44V 6、PCNA、CⅣ单克隆抗体表达情况。结果 正常组织对CD44V 6不表达 ;有淋巴结转移的宫颈癌组织对CD44V 6呈过表达 ,阳性率为 81.6% ,无淋巴结转移的宫颈癌组织对CD44V 6呈低表达 ,阳性率为 3 6.4% ;CD44V 6阳性表达组伴有PCNA过表达和CⅣ低表达 ,与CD 44V 6阴性表达组比较有显著性差异。结论 CD 44V 6与肿瘤淋巴结转移有关 ,CD44V 6阳性表达组织可能具有转移潜能。

Objective To study the expression of vascular endothelial growth factor(VEGF),nm23 in cervical squamous carcinoma and cervical precancerous lesions and the relationship between microvessel density in cervical squamous carcinoma and the angiogenesis of the tumor.Methods 50 cases of cervical squamous carcinoma,28 cases of cervical intraepithelial neoplasia (CIN) and 12 cases of normal cervical tissue sample were stained for VEGF,nm23 and CD34 by immunohistochemistry method.Quantitation of microvessel was performed...

Objective To study the expression of vascular endothelial growth factor(VEGF),nm23 in cervical squamous carcinoma and cervical precancerous lesions and the relationship between microvessel density in cervical squamous carcinoma and the angiogenesis of the tumor.Methods 50 cases of cervical squamous carcinoma,28 cases of cervical intraepithelial neoplasia (CIN) and 12 cases of normal cervical tissue sample were stained for VEGF,nm23 and CD34 by immunohistochemistry method.Quantitation of microvessel was performed and analyzed in a conjunction with the clinical features of the tumor.Results VEGF positive expression rate in cervical squamous carcinoma was significantly higher than that in normal cervical tissue and CINⅠ?Ⅱ tissue.VEGF expression was correlated to MVD,invasion,metastasis and the clinical stage of the tumor.MVD in the tumor was correlated to metastasis of the tumor.The positive expression rate of nm23 in normal cervical tissue was 100.0%,but it was remarkably decreased in cervical squamous carcinoma.Our analysis indicated that no significant relationship was found between the state of nm23 expression and invasion,metastasis and the clinical stage of the tumor.Conclusion The higher expression of VEGF and the lower expression of nm23 in cervical squmous carcinoma may play an important role in the microvessel growth and angiogenesis of cervical squamous carcinoma.

目的 探讨宫颈鳞癌及癌前病变组织中VEGF、nm 2 3表达情况及MVD与宫颈鳞癌发展浸润的关系。方法 采用免疫组化方法对 5 0例宫颈鳞癌、2 8例CIN和 12例正常宫颈组织进行VEGF、nm 2 3和CD3 4检测 ,计数癌组织MVD ,并结合临床资料进行统计分析。结果 宫颈鳞癌VEGF阳性表达率明显高于正常组织和CINⅠ、Ⅱ级组织 ,VEGF表达与癌组织MVD、肿瘤浸润、转移和临床分期密切相关 ;癌组织MVD与肿瘤转移密切相关 ;正常宫颈组织nm 2 3均呈阳性表达 ,而宫颈浸润癌组织nm 2 3表达率明显降低 ,但nm 2 3表达与肿瘤浸润、转移和临床分期无明显相关性。结论 宫颈鳞癌组织VEGF呈高表达、nm 2 3呈低表达 ,可能在宫颈鳞癌血管生长、肿瘤浸润转移过程中起重要作用

 
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