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膀胱移行细胞癌组织
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  transitional cell carcinoma of bladder
     Objective To investigate the expression of E-cadherin and its relationship with serum CA125.Methods Immunohistochemical staining and radioimmunoassay were applied to detect the expression of E-cadherin in 60 cases of transitional cell carcinoma of bladder and the value of serum CA125,and to analyze the relationship between them.
     目的探讨膀胱移行细胞癌组织中E-cadherin的表达及其与CA125的关系,以及两者与肿瘤临床特征的关系。 方法采用免疫组织化学染色法及放射免疫法检测60例膀胱移行细胞癌标本E-cadherin的表达及血清CA125值,分析表达水平与CA125值的关系。
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     The Expression and Significance of Ki-67 and CyclinD_1 in Transitional Cell Carcinoma of Bladder
     膀胱移行细胞癌组织中Ki-67抗原和cyclinD_1的表达及其意义
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     Expression of E-cadherin in transitional cell carcinoma of bladder and its relationship with serum CA125
     膀胱移行细胞癌组织中E-cadherin的表达及与血清CA125检测的关系
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     The expressions of PCNA,MMP-2 in transitional cell carcinoma of bladder(TC CB) and their meanings
     膀胱移行细胞癌组织中PCNA、MMP-2的表达及意义
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     Methods Immunohistoehemistry SP method was used to detect the expression and microvessel density of CD_(105)in 6 tissues of bladder papilloma and in 30 tissues of primary transitional cell carcinoma of bladder.
     方法:采用免疫组织化学SP法测定6例膀胱乳头状瘤,30例膀胱移行细胞癌组织CD105的表达及M VD。
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  transitional cell bladder cancer
     Clinical and Prognostic Significance of PCNA Expression and Tumor Interstitial Vascular Density in Transitional Cell Bladder Cancer
     膀胱移行细胞癌组织间质微血管密度和增殖细胞核抗原的表达及意义
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     Objective: To evaluate the clinical and prognostic significance of proliferating cell nuclear antigen (PCNA) expression and tumor interstitial microvessel density (MVD) in transitional cell bladder cancer.
     目的 :探讨膀胱移行细胞癌组织中增殖细胞核抗原 (PCNA)与肿瘤间质微血管密度 (MVD)的表达及其临床与预后的意义。
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     Methods nm23 gene expression in 45 cases with transitional cell bladder cancer were studied by means of LSAB immunohistochemistry.
     方法 :应用免疫组织化学方法检测 4 5例膀胱移行细胞癌组织nm2 3基因表达。
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     Objective To evaluate the clinical and prognostic significance of proliferating cell nuclear antigen (PCNA) expression and to study tumor interstitial microvessel density (MVD) in transitional cell bladder cancer.
     目的 探讨膀胱移行细胞癌组织中增殖细胞核抗原 (proliferatingcellnuclearantigen ,PCNA)与肿瘤间质微血管密度 (microvesseldensity ,MVD)和肿瘤侵袭力、复发的关系及意义。
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  bladder transitional cell carcinoma tissue
     The Experimental Study of Id1 Expression in Bladder Transitional Cell Carcinoma Tissue and Exfoliated Urothelial Cells
     膀胱移行细胞癌组织及尿脱落细胞Id1表达的实验研究
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     Expression of COX- 2 protein in bladder transitional cell carcinoma tissue
     膀胱移行细胞癌组织中环氧合酶-2蛋白的表达
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     Expression of matrix metalloproteinase in bladder transitional cell carcinoma tissue
     膀胱移行细胞癌组织中MMP-2、MMP-9蛋白的表达
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     CONCLUSIONS:The results suggested that proapoptosis gene protein Bak are differently expression in most bladder transitional cell carcinoma,Bak gene may take part in the modulation of apoptosis in bladder transitional cell carcinoma and the expression of Bak is closely related with the degree of bladder transitional cell carcinoma tissue differentiation.
     结论 :促凋亡基因蛋白Bak在大多数膀胱移行细胞癌组织中有不同程度的表达 ,Bak基因可能参与膀胱移行细胞癌的凋亡调节 ,并与膀胱移行细胞癌组织的分化程度有关
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     Conclusion:The results suggest that pr oapoptosis gene bak are differently expressed in most bladder transitional cel l carcinoma,bak gene may take part in the modulation of apoptosis in bladder tra nsitional cell carcinoma and the expression of bak mRNA is closely related with the degree of bladder transitional cell carcinoma tissue differentiation.
     结论 :促凋亡基因bak在大多数膀胱移行细胞癌组织中有不同程度的表达 ,bak基因可能参与膀胱移行细胞癌的凋亡调节 ,并与膀胱移行细胞癌组织的分化有关。
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  “膀胱移行细胞癌组织”译为未确定词的双语例句
     Results The positive rate of △Np63 and MDM2 protein expression in the TCC of urinary bladder were 83.3% and 42.9% respectively;
     结果 膀胱移行细胞癌组织中,△Np63和MDM2阳性表达率分别为83.3%和42.9%;
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     Expression of MAGE-A1, A2, A3, A4 in urinary transitional cell carcinoma tissue and cell lines
     MAGE-A1,A2,A3,A4在膀胱移行细胞癌组织及细胞株中基因表达的研究
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     Clinical Significance of hTERT and p16,CyclinD_1,Rb Expression in the Transitional Cell Carcinoma of Urinary Bladder
     膀胱移行细胞癌组织中hTERT和p16,cyclinD_1,RB的表达及意义
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     Results The positive rates of HPV types 6,11,16 and 18 were 6.7 %, 5.3 %, 33.3 % and 6.7 %,respectively.
     结果 膀胱移行细胞癌组织中HPV6、11、16和 18的阳性率分别为 6 .7%(5 75 ) ,5 .3 % (4 75 ) ,33 .3 % (2 5 75 )和 6 .7% (5 75 )。
短句来源
     Expression and significance of Livin in bladder transitional cell carcinomas
     凋亡抑制因子Livin在膀胱移行细胞癌组织中的表达及意义
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  transitional cell carcinoma of bladder
Recurrence risk factors in patients with transitional cell carcinoma of bladder
      
Cloning of human Uroplakin II gene from Chinese transitional cell carcinoma of bladder and construction of its eukaryotic expres
      
Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder
      
The expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder (TCCB) and its clinical significance were investigated.
      
The immunocytochemical demonstration of basement membrane deposition in transitional cell carcinoma of bladder
      
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  transitional cell bladder cancer
Selected risk factors for transitional cell bladder cancer
      
ABH isoantigens, histology and DNA ploidy in 36 consecutive patients with transitional cell bladder cancer.
      
Cell proliferation of transitional cell bladder cancer (TCC) was determined by MIB-1 immunolabeling, volume-corrected mitotic index (M/V index) and S-phase fraction measurement in 207 patients with superficial (Ta-T1) bladder cancer.
      
Fifteen patients with measurable metastatic transitional cell bladder cancer were treated with VP 16-213 100 mg/m2 IV daily for 4 days, repeated every 3 weeks.
      
So far, TN expression has not been described in transitional cell bladder cancer (TCC), and there is no information on the prognostic significance of its in situ expression.
      
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To investigate the correlation between Rb tumor suppressor gene and bladder and renal cell carcinoma,the gene in primary RCC, baldder carcinoma and cell lines Were analyzed by northern blot,One RCC and two bladder carcinoma cell lines showed noramal Rb expression.One of 13 RCC,and two hing-grade bladder carcinomas lacked Rb mRNA expression. None of the low-grade carcimomas showed an altration in Rb gene,The result suggests that the loss of Rb gene corrclates with bladder carcinoma and is more frequent in high-grade...

To investigate the correlation between Rb tumor suppressor gene and bladder and renal cell carcinoma,the gene in primary RCC, baldder carcinoma and cell lines Were analyzed by northern blot,One RCC and two bladder carcinoma cell lines showed noramal Rb expression.One of 13 RCC,and two hing-grade bladder carcinomas lacked Rb mRNA expression. None of the low-grade carcimomas showed an altration in Rb gene,The result suggests that the loss of Rb gene corrclates with bladder carcinoma and is more frequent in high-grade ones Rb loss might have a role in certain renal cell carcinoma.

对正常肾和肾细胞癌组织,正常膀胱粘膜和膀胱移行细胞癌组织以及肾癌细胞和膀胱癌细胞株BIU-87和E-J中的抗癌基因Rb进行Northernblot分析。肾和膀胱癌细胞都表达正常的RbmRNA。1/13例肾癌组织和2/8例膀胱癌组织中发现Rb基因缺失。此2例Rb缺失的膀胱癌均为低分化肿瘤,在分化较高的膀胱癌中未发现Rb基因缺失。结果表明,Rb基因缺失与膀胱癌的关系密切,同时与肿瘤的分化程度有关。结合文献对Rb抗癌基因与泌尿系肿瘤的关系及其在肿瘤发生中的作用进行讨论。

Endothelin(ET)is a potent vasocontrictor peptide released from vascular endothelial cells.ET also has other biological functions relevant to tumorgenesis,including mitogenic and angiogenic activities. The expression of ET in human bladder cancer tissues and bladder cancer BIU-87 cell line was detected,and the effect of ET on the proliferation of BIU-87 was studied. Northern blot showed that the level of ET-1 mRNA expression was more than 4-fold higher in tumor tissues than the surrounding noncancerous tissues...

Endothelin(ET)is a potent vasocontrictor peptide released from vascular endothelial cells.ET also has other biological functions relevant to tumorgenesis,including mitogenic and angiogenic activities. The expression of ET in human bladder cancer tissues and bladder cancer BIU-87 cell line was detected,and the effect of ET on the proliferation of BIU-87 was studied. Northern blot showed that the level of ET-1 mRNA expression was more than 4-fold higher in tumor tissues than the surrounding noncancerous tissues (n=4).Using radioimmunoassay,it was also found that the content of ET in tumor tissues was 6-8 fold higher than the surrounding noncancerous tissues (n=4). In BIU-87 cells, the level of ET concentration was increased (38%and 47%) after TPA (100 ng/mL) treatment (4 h and 8 h). The secretion level of ET in BIU-87 cells was also slightly stimulated by TPA (100 ng/mL,8 h). After treated with ET-antiserum,the  ̄3H-TdR incorporation was markedly decreased (57%) in BIU-87 cells whereas it was also decreased (35%) after treated BIU-87 with ET receptor A antagonist──BQ_(123).In conclusion,ET was markedly expressed both in human bladder cancer tissues and BIU-87 cells, especially when the cells were induced by TPA. It seems that ET has proliferative effgct on bladder cancer cells and this effect can be depressed by ET-antiserun or ET receptor A antagonist──BQ_(123).

应用Northernblot杂交技术及放射免疫方法对人膀胱移行细胞癌组织中内皮素-1mRNA及内皮素活性分子的表达水平进行检测,研究了佛波酯对人膀胱移行细胞癌BIU-87细胞中内皮素活性分子表达水平的调节作用,并探讨了内皮素抗血清及内皮素A型受体竞争性拮抗剂BQ_(123)对BIU-87细胞DNA合成的影响。结果表明,人膀胱移行细胞癌组织中内皮素-lmRNA及内皮素活性分子的表达水平明显高于相应的癌旁组织,佛波酯可促进BIU-87细胞合成和分泌内皮素,内皮素抗血清及BQ_(123)可抑制BIU-87细胞合成DNA。提示内皮素在膀胱癌发展及BIU-87细胞恶性增殖中可能起重要作用。

Abstract The expression of P_(21) was detected in 41 samples of bladder tissue with ABC immunoelectrophresis. The positive rate of P_(21) expression was 86.2% (25/29) in bladder transitional cell carcinoma, 50%(3/6) in para-carcinoma tissue, 33.3% (1/3) in normal bladder mucosa and 66.7% (2/3) in bladder inflammatory mucosa. The immunoelectrophoretic film computing densitometer intergrated area was 1530, 1938, 3605 in grade I, Ⅱ, Ⅲ, of bladder carcinoma respectively. The ave rage integrated area of immunoelectrphoretic...

Abstract The expression of P_(21) was detected in 41 samples of bladder tissue with ABC immunoelectrophresis. The positive rate of P_(21) expression was 86.2% (25/29) in bladder transitional cell carcinoma, 50%(3/6) in para-carcinoma tissue, 33.3% (1/3) in normal bladder mucosa and 66.7% (2/3) in bladder inflammatory mucosa. The immunoelectrophoretic film computing densitometer intergrated area was 1530, 1938, 3605 in grade I, Ⅱ, Ⅲ, of bladder carcinoma respectively. The ave rage integrated area of immunoelectrphoretic P_(21) band was 2595 in bladder carcinoma tissue, 963 in para-carcinoma, 682 in normal mucosa, 1678 in bladder inflammatory mucosa.

采用ABC免疫电泳检测29例膀胱移行细胞癌组织、6例癌旁粘膜、3例膀胱炎粘膜和3例正常膀胱粘膜的P21蛋白表达,结果25例膀胱癌组织、3例癌旁粘膜、1例正常膀胱粘膜、2例膀胱炎粘膜有P21蛋白表达。随肿瘤分级增高,P21蛋白条带的光密度积分增加;肿瘤组织P21蛋白光密度积分高于癌旁粘膜,癌旁粘膜又高于正常膀胱粘膜。

 
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