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自发凋亡率
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  spontaneous apoptosis
     Results:Compared to the spontaneous apoptosis(55±10)% of neutrophils cultared in vitro for 24 h,the cell apoptosis of neutrophils cultured with Mtb-Ag(1.125 mg/ml) decreased(31±3)%(P<0.01);
     结果:与中性粒细胞体外培养24 h后自发凋亡(55±10)%相比,加入Mtb-Ag(1.125 mg/ml)后,中性粒细胞自发凋亡率(31±3)%明显降低(P<0.01);
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     Results In BTCC, the spontaneous apoptosis index AI was (3.0±1.5)%, the positive rate of p27kip1 was 58.0 %(29/50).
     结果在膀胱移行细胞癌中,自发凋亡率AI均数为(3.0±1.5)%,p27kip1基因的阳性表达率为58.0%(29/50)。
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     Clinical Significance of Spontaneous Apoptosis and the Expression of bcl-2, PCNA, p27kip1 in Transitional Cell Carcinoma of Bladder
     自发凋亡率、PCNA、bcl-2、p27kip1在人膀胱移行细胞癌中表达的临床意义
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     Clinical significance of the expression of ki-67,bcl-2,bax,p53 and the spontaneous apoptosis in human renal clear cell carcinoma
     人肾透明细胞癌中ki-67 bcl-2 bax p53表达及癌细胞自发凋亡率的临床意义
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     Results: The spontaneous apoptosis rate in leukemia (4.04%± 2.05%) was significantly lower than those in MDS(7.42%±6.39%) and anemia (7.58% ±5.86%)(P<0.05).
     结果:(1)白血病骨髓细胞自发凋亡率为(4.04±2.25)%低于MDS(7.42±6.39)%及贫血组(7.58±5.86)%(P<0.05)。
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  “自发凋亡率”译为未确定词的双语例句
     Results The apoptosis rate of HSC-T6 cultured in serum free medium was (2.99±0.98)% (by flow cytometry) and (5.69±1.52)% (by Hoechest 33342 staining) , respectively.
     结果 无血清培养的HSC-T6自发凋亡率分别为(2.99±0.98)%(流式细胞仪检测)和(5.69±1.52)%(Hoechest 33342直接染色法),血管紧张素Ⅱ能剂量依赖性的抑制其凋亡。
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     Results The results showed the automatic apoptosis rate of humna Eca - 109 cells was 10.3% and after the induction by 8 - Br - cAMP the cells with apoptosis bend increased.
     结果食管癌109细胞株自发凋亡率为10.3%,经8-Br-cAMP诱导后凋亡倾向细胞增加。
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     The spontaneous and radiation-induced apoptosis rates were determined by flow cytometry at 0, 24, 48, and 72 h after exposure to ~ 60 Co γ-rays.
     实验于照射后0、24、48和72h,用细胞流式术动态检测AT和GM细胞的自发凋亡率及60Coγ射线照射诱发的凋亡率。
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     The rates of BIU-87 cells were 45.69%,47.70% and 44.50%; the rates of T-24 cells were 43.79%,46.17% and 44.50% after adriamycin,vincristine and cisplatin cytotoxic drugs acting for 48 h. There were significant differences of the rates before and after use of these drugs(P<0.01).
     3种细胞自发凋亡率分别为1.15%、1.40%、0.90%,3种化疗药物作用48 h后,B IU-87细胞凋亡率分别为45.69%、47.70%、44.50%,T-24细胞凋亡率分别为43.79%、46.17%、44.50%,用药前后差异有统计学意义(P<0.01)。
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     Results ( 1 ) Apoptosis were observed in the lymphocytes stimulated with PHA both from healthy donors ( 20. 9% ± 3. 4% ) and patients with Behcet' s disease ( 16. 3% ± 2. 7% ). But the apoptotic rale was significantly different ( t = 2. 36 , P < 0. 05 ) between patients and healthy donors.
     结果 (1)正常人和Behcet病患者外周血淋巴细胞经PHA活化后均可发生凋亡,其自发凋亡率分别为20.9%±3.4%和16.3%±2.7%,二者具有显著性差异(t=2.36,P<0.05);
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  相似匹配句对
     The spontaneous apoptosis rate in AT fibroblasts was higher than that in GM fibroblasts;
     AT细胞的自发凋亡高于GM细胞;
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     Ⅱ, The waveform of the spontaneous discharge potential in auditory never, Ⅲ, The discharge rate of spontaneous discharge in auditory nerve primary fibers.
     ③听神经的自发放电;
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     Apoptosis rate shows an increasing trend;
     凋亡呈现增加的趋势;
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     Flurorescence staining was used to detect the percentage of apoptosis.
     荧光染色检测凋亡;
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     Significance of the detection of spontaneous apoptosis and the expression of p27kip1 in transitional cell carcinoma of bladder
     联合检测自发凋亡及p27kip1在膀胱移行细胞癌中的意义
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  spontaneous apoptosis
Neither the hormones separately nor their combinations affected the spontaneous apoptosis of T-cells.
      
A low dose of CG (10 IU/ml) increased the spontaneous apoptosis of neutrophils, whereas its combination with estradiol and progesterone corresponding to that of trimester III of pregnancy significantly decreased this parameter.
      
The levels of spontaneous apoptosis and proliferation of the rat thymic and spleen cells, as well as their regulation by the hypothalamo-hypophysial system were studied during perinatal development.
      
It was demonstrated that an initially low level of spontaneous apoptosis is registered in all surveyed patients.
      
Spontaneous apoptosis has been shown to predict tumor response to preoperative radiochemotherapy in rectal cancer.
      
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URPOSE To investigate apoptosis in irradiated hepatocarcinoma cell line and its doseresponse curve.METHODS Apoptosis in QGY7703 human hepatocarcinoma cell line irradiated in vitro were quantified using FCM,EM and TUNEL.RESULTS Spontaneous apoptosis fraction in QGY7703 was 422%.The frequency of apoptosis in irradiated QGY7703 was related to dose given and post irradiation incubation time.Its plateau value was at 8 Gy,or 24 hours of incubation time.CONCLUSION The results of this study suggest that human...

URPOSE To investigate apoptosis in irradiated hepatocarcinoma cell line and its doseresponse curve.METHODS Apoptosis in QGY7703 human hepatocarcinoma cell line irradiated in vitro were quantified using FCM,EM and TUNEL.RESULTS Spontaneous apoptosis fraction in QGY7703 was 422%.The frequency of apoptosis in irradiated QGY7703 was related to dose given and post irradiation incubation time.Its plateau value was at 8 Gy,or 24 hours of incubation time.CONCLUSION The results of this study suggest that human hepatocarcinoma cell line is apoptosis resistant.

目的研究人肝癌细胞株受照射后发生凋亡的时间、剂量关系。方法用TUNEL及流式细胞仪方法观察QGY-7703人肝癌细胞株受照射后凋亡情况。结果QGY-7703细胞株自发凋亡率为4.22%,受照射后凋亡发生随剂量增加和温育时间延长而增加。当剂量达8Gy或温育时间达24小时趋于稳定。结论与淋巴造血系统来源的瘤株相比,人肝癌细胞株自发凋亡较低,受照射后增加较少,提示肝癌中凋亡易感细胞比例较低

Objective To study the occrrence of apoptosis after human Eca - 109 cells were induced with 8 - Br -cAMP. Method The conduction of apoptosis ther induction was studied by TUNEL method. Results The results showed the automatic apoptosis rate of humna Eca - 109 cells was 10.3% and after the induction by 8 - Br - cAMP the cells with apoptosis bend increased. Conclusions It is suggested that 8 - Br - cAMP have the trend of promoting the apoptosis of human Eca -109 cells.

目的研究人食管癌109细胞株经8-Br-cAMP诱导后细胞凋亡的发生。方法用TUNEL法观察诱导后细胞凋亡情况。结果食管癌109细胞株自发凋亡率为10.3%,经8-Br-cAMP诱导后凋亡倾向细胞增加。结论8—Br-cAMP可具有促进入食管癌细胞凋亡的倾向。

Objective To study the ability of the chemotherapeutic drugs for inducing apoptosis and its relation to the Bcl 2 expression of leukemic cells, the prognostic factors and the efficacy of clinical treatment. Methods The morphologic study, agarose gel electrophoresis and flow cytometry were utilized to investigate the apoptosis of acute lymphoid leukemia (ALL) and hemoblastocy acute leukmia (HAL) cells induced by vincristine (VCR), dexamethasone (Dex), cytosine arabinoside (Ara C) and daunorubicin (DNR) at...

Objective To study the ability of the chemotherapeutic drugs for inducing apoptosis and its relation to the Bcl 2 expression of leukemic cells, the prognostic factors and the efficacy of clinical treatment. Methods The morphologic study, agarose gel electrophoresis and flow cytometry were utilized to investigate the apoptosis of acute lymphoid leukemia (ALL) and hemoblastocy acute leukmia (HAL) cells induced by vincristine (VCR), dexamethasone (Dex), cytosine arabinoside (Ara C) and daunorubicin (DNR) at clinically relevant dosage. The flow cytometry was also used to study the expression of Bcl 2 on leukemic cells.Results (1) Exposure of leukemic cells to clinically relevant concentrations of VCR, Dex, Ara C and DNR for 20~24 hours resulted in apoptosis in most patients (22/24, 19/24, 6/11 and 6/6, respectively). Necrosis was found in leukemic cells of some patients (3/11) on DNR treatment. (2)The proportion of apoptotic cells induced by some chemotherapeutic drugs showed positive correlations with each other. The correlation coefficient of apoptotic rate in VCR group and Dex group was 0.821 ( P <0.001), in Ara C group and Dex group was 0.994 ( P <0.001). (3)The apoptotic rate of fresh leukemic cells was (3.2±1.9)%. ALL and HAL cells cultured for 24 hours in vitro would develop spontaneous apoptosis in (18.2±13.5)%. The spontaneous apoptosis rate correlated positively to the apoptosis rates induced by VCR, Dex and Ara c, the relevant coefficients were 0.878 ( P <0.001), 0.893 ( P <0.001) and 0.882 ( P <0.05), respectively. (4)CD 34 was an independent factor influencing apoptotic rates, the apoptotic rate was significantly lower in CD 34 positive group (CD 34 ≥30%) than that in CD 34 negative group. (5)There was no relationship between the expression of Bcl 2 and the apoptic rate of leukemic cells. Conclusion Inducing apoptosis is an important mechanism of killing leukemic cells by chemotherapeutic drugs.

目的 研究化疗药物诱导白血病细胞凋亡的作用及其与Bcl 2表达、临床预后指标及临床疗效的关系。方法 利用形态学观察、DNA琼脂糖凝胶电泳、凋亡指示抗体APO 2 .7结合流式细胞仪检测法 ,研究临床治疗相关剂量的化疗药物诱导急性淋巴细胞白血病 (ALL)细胞、急性混合性白血病 (HAL)细胞的凋亡及其Bcl 2表达率。结果  (1)用临床治疗相关剂量的长春新碱 (VCR)、地塞米松(Dex)、柔红霉素 (DNR)、阿糖胞苷 (Ara C)作用 2 0~ 2 4h后 ,多数患儿 (分别为 2 2 /2 4、19/2 4、6 /11、6 /6 )的白血病细胞可发生凋亡。但是DNR引起部分患儿 (3/11)的白血病细胞发生坏死。 (2 )VCR组与Dex组以及Ara C组与Dex组的诱导凋亡率呈高度正相关 ,相关系数分别为 0 .82 1(P <0 .0 0 1)和 0 .994(P <0 .0 0 1)。 (3)新鲜离体白血病细胞的凋亡率为 (3.2± 1.9) %。ALL及HAL细胞体外培养 2 4h后的自发凋亡为 (18.2± 13.5 ) % ,且与VCR ,Dex及Ara C的诱导凋亡率呈正相关 ,相关系...

目的 研究化疗药物诱导白血病细胞凋亡的作用及其与Bcl 2表达、临床预后指标及临床疗效的关系。方法 利用形态学观察、DNA琼脂糖凝胶电泳、凋亡指示抗体APO 2 .7结合流式细胞仪检测法 ,研究临床治疗相关剂量的化疗药物诱导急性淋巴细胞白血病 (ALL)细胞、急性混合性白血病 (HAL)细胞的凋亡及其Bcl 2表达率。结果  (1)用临床治疗相关剂量的长春新碱 (VCR)、地塞米松(Dex)、柔红霉素 (DNR)、阿糖胞苷 (Ara C)作用 2 0~ 2 4h后 ,多数患儿 (分别为 2 2 /2 4、19/2 4、6 /11、6 /6 )的白血病细胞可发生凋亡。但是DNR引起部分患儿 (3/11)的白血病细胞发生坏死。 (2 )VCR组与Dex组以及Ara C组与Dex组的诱导凋亡率呈高度正相关 ,相关系数分别为 0 .82 1(P <0 .0 0 1)和 0 .994(P <0 .0 0 1)。 (3)新鲜离体白血病细胞的凋亡率为 (3.2± 1.9) %。ALL及HAL细胞体外培养 2 4h后的自发凋亡为 (18.2± 13.5 ) % ,且与VCR ,Dex及Ara C的诱导凋亡率呈正相关 ,相关系数分别为 0 .878(P <0 .0 0 1)、0 .893(P <0 .0 0 1)、0 .882 (P <0 .0 5 )。 (4)CD3 4是影响白血病细胞凋亡率的独立指标。阳性组 (CD3 4≥ 30 % )的VCR、Dex诱导凋亡率及自发凋亡率明显低于阴性组。 (5 )白血病细胞的Bcl 2表达率与药物诱导凋亡率及自

 
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