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鳞癌组织
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  squamous cell carcinoma
    Studies on Expression and Significance of HSP27 and HSP70 in Esophageal Squamous Cell Carcinoma
    热休克蛋白27和70在食管鳞癌组织中的表达及其意义的研究
短句来源
    Expression and Functional Study of SLP-2 Gene in Cervical Squamous Cell Carcinoma
    SLP-2基因在宫颈鳞癌组织中的表达及其功能的初步研究
短句来源
    Expression of nm23 and p53 Protein in Laryngeal Squamous Cell Carcinoma and It's Neighboring Dysplastie Tissue
    nm23和p53蛋白在喉鳞癌组织中表达的意义
短句来源
    Detection of the mutation of p16 tumor suppressor gene in esophageal squamous cell carcinoma
    食管鳞癌组织中抑癌基因p16突变的检测
短句来源
    Expression and significance of ICE in esophageal squamous cell carcinoma
    食管鳞癌组织中ICE蛋白的表达及其意义
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  squamous cell carcinomas
    Methods Immunohistochemical S-P method was used in this study to detect the expression of cyclinD1,p27 and c-erbB-2 in 62 squamous cell carcinomas of tongue.
    方法应用免疫组织化学S-P 法回顾性研究62例舌鳞癌组织中的cyclinD1、p27及c-erbB-2的表达水平。
    Objective:To study the expression of N - myc downstream regulated gene 1(NDRG1) in e-sophageal squamous cell carcinomas.
    目的研究分化相关基因NDRG1(N-myc Downstream Regulated Gene 1,NDRG1)在食管鳞癌组织中的蛋白表达。
    Protein Kinase C and Its Inhibitor Activity in Oral Squamous Cell Carcinomas
    口腔鳞癌组织中蛋白激酶C及其抑制物活性的研究
短句来源
    The expression of Mdm2 protein and p53 mutation in lung squamous cell carcinomas and their clinicopathological significance
    肺鳞癌组织Mdm2蛋白表达p53基因突变相关性研究
短句来源
    The expression of CDK_4, Cyclin D_1, P~(16) proteins in 105 patients with laryngeal squamous cell carcinomas
    喉鳞癌组织中CDK_4、cyclin D_1、P~(16)蛋白表达
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  human squamous cell carcinoma
    The expressions and significance of CyclinD1, TGF-β1 and GST-π in human squamous cell carcinoma of esophagus
    CyclinD1、TGF-β1、GST-π在食管鳞癌组织中的表达和意义
短句来源
    The Dynamic Expression and Clinic Significance of MMP-2 and TIMP-2 in Human Squamous Cell Carcinoma Tissue and the Correlation with Metastases and Prognosis
    MMP-2、TIMP-2在人肺鳞癌组织中的动态表达及其临床意义
短句来源
    Stable transfection of BEP2D and BERP35T2 cells with the full length Smad7 cDNA construct results in marked increase of the proliferation of cells and loss of the growth inhibitory response to TGF-β1. The expression of Smad7 is increased in tumor tissues of human squamous cell carcinoma.
    3)对肺鳞、腺癌组织的免疫组织化学研究表明 Smad7 在肺鳞癌组织中表达增高。
短句来源
    Methods: Eighty-one specimens of human squamous cell carcinoma of esophagus and 43 normal esophagus as control were assessed by immunohistochemical method (SP method).
    方法:采用免疫组织化学法,对81例食管鳞癌组织和43例正常食管组织Cyclin-D1、TGF-β1、GST-π的表达进行检测。
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  “鳞癌组织”译为未确定词的双语例句
    Alternation of P53 Gene in Esophageal Squamous Carcinoma and the Influence of Wild-type P53 Gene Transfection on Its Cellular Radiosensitivity
    食管鳞癌组织P53基因改变的检测及wt-P53基因转染对食管鳞癌细胞射线敏感性影响的研究
短句来源
    Correlation Between DNA Ploidy and AgNOR Counts in Esophageal Carcinoma
    食管鳞癌组织AgNOR计数与DNA倍体的关系
短句来源
    Detection of human papillomavirus genomes 6B/11 and 16/18 DNA in laryngeal carcinomas
    人乳头瘤病毒DNA 6B/11、16、18在喉鳞癌组织中的表达
短句来源
    RT PCR for detection of expression of GST π gene in primary human esophageal carcinoma
    RT-PCR检测食管鳞癌组织中GST-π基因的表达
短句来源
    Relationship between Human Papillomavirus E7 Protein and Rb Gene Product in Fresh Tissues of Squamous Cervical Carcinoma
    子宫颈鳞癌组织中人乳头状瘤病毒E_7蛋白与Rb基因产物的关系
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  squamous cell carcinoma
Regulation of matrix metalloproteinase-9 transcription in squamous cell carcinoma of uterine cervix: the role of human papilloma
      
Matrix metalloproteinase-9 (MMP-9) plays an important role in initiation and progression of squamous cell carcinoma (SCC) of human uterine cervix.
      
The NOLA2 and RPS3A genes as highly informative markers of human squamous cell carcinoma of lung
      
An analysis of the libraries revealed two genes, NOLA2 and RPS3A, whose expression in patients with squamous cell carcinoma increased by 70%.
      
A high frequency of enhanced expression of these genes in the cancer makes them highly informative markers of squamous cell carcinoma, which, together with other markers, can be used for reliable diagnosis of the disease.
      
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  squamous cell carcinomas
To reveal early genetic alterations of chromosome 6 that are important for CC progression, we analyzed the loss of heterozygosity (LOH) in DNAs from 45 CIN cases, 47 microcarcinomas, and 19 invasive squamous cell carcinomas stage IB.
      
We investigated 37 head and neck squamous cell carcinomas (HNSCC) at different stages, using immunohistochemical staining for CD4+ infiltrates and real-time reverse transcription polymerase chain reaction (RT-PCR) detection of CD4 mRNA.
      
Effect of the Hypoxic Cell Sensitizer Isometronidazole on Local Control of Two Human Squamous Cell Carcinomas after Fractionated
      
Higher incidence of positive staining wasalso found in squamous cell carcinomas without hilar or mediastinal lymph node metastasis (16/27, 59.3%) than in those with hilar or mediastinal lymph node involvement (4/19, 21.1%;P>amp;lt;0.05).
      
Basal cell and squamous cell carcinomas comprise the majority of non-melanoma skin cancers.
      
更多          
  human squamous cell carcinoma
The NOLA2 and RPS3A genes as highly informative markers of human squamous cell carcinoma of lung
      
13-cis Retinoic Acid in Combination with Interferon-α Enhances Radiation Sensitivity of Human Squamous Cell Carcinoma Cells of t
      
We previously reported that pemphigus vulgaris (PV)-IgG caused the formation of Dsg3-depleted desmosomes in normal human cultured keratinocytes and DJM-1, a human squamous cell carcinoma cell line.
      
Implanted human squamous cell carcinoma cells in athymic nude mice showed that carcinoma cells removed immediately following PDT remained viable, while tumors left in situ became necrotic.
      
In vitro effects of high-energy pulsed ultrasound on human squamous cell carcinoma cells
      
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Transformation of NIH3T3 cells with high molecular weight DNA isolated from human squa- mous cell carcinoma of lung,was performed by the calcium phosphate precipitation technique.The morpho- logically transformed cells could grow in colony on soft agar.The DNA isolated from primary transformants could induce second round transfection.These transformants were tumorigenic in nude mice.Hybridization of DNA from transformants digested with restriction endonuclease EcoRI with human ALu repeat sequence was positive.Amplification...

Transformation of NIH3T3 cells with high molecular weight DNA isolated from human squa- mous cell carcinoma of lung,was performed by the calcium phosphate precipitation technique.The morpho- logically transformed cells could grow in colony on soft agar.The DNA isolated from primary transformants could induce second round transfection.These transformants were tumorigenic in nude mice.Hybridization of DNA from transformants digested with restriction endonuclease EcoRI with human ALu repeat sequence was positive.Amplification of c-myc gene and DNA sequence homologous to v-fos gene were found in these transformants.

本文用磷酸钙沉淀技术,以人肺鳞癌组织高分子量 DNA 进行了小鼠成纤维细胞NIH3T3的转化实验。得到的转化细胞能在软琼脂板上生长;可诱导 NIH3T3细胞二轮转化;在裸鼠体内有明显的致瘤性;其 DNA 经酶切后与人 ALU 重复序列探针杂交呈阳性反应;并证明有 c~myc 基因扩增及有 v-fos 同源宁列的存在。

Histochemical and immunohistochemical studies were made on 89 cases of the benign and malignant lesions of the gallbladder. Normal gallbladder epithelium showed a predominance of sulphated mucosubstance Gastric—type and intestinal —type metaplasia were demonstrated in dysplastic areas of the bordering areas of the tumor and gallbladder carcinomas. The positive rates of metaplastic changes have no significant difference (P>0.05) between dysplasias and bordering areas of the carcinoma. 47 cases of 70 gallbladder...

Histochemical and immunohistochemical studies were made on 89 cases of the benign and malignant lesions of the gallbladder. Normal gallbladder epithelium showed a predominance of sulphated mucosubstance Gastric—type and intestinal —type metaplasia were demonstrated in dysplastic areas of the bordering areas of the tumor and gallbladder carcinomas. The positive rates of metaplastic changes have no significant difference (P>0.05) between dysplasias and bordering areas of the carcinoma. 47 cases of 70 gallbladder carcinoma represented metaplastic changes. The positive rate of metaplasia was lower in poor differential carcinomas (P<0.01). With gradually increasing degree of dysplastic epithilium, the quantity of mucin decreased gradually and dyspiastic epithelium contained mainly neutral mucin and nonsulphated acid mucin. This study suggested that metaplasia of gallbalder epithetium was significantly related to the development of gallbladder carcinoma. Some cases of dysplatic epithelium, bordering areas of the squamous cell carcinoma and part of squamous cell carcinoma (71.4%) represented positive reaction with monoclonal antibody K_(27) of large molecular keratin. It is suggeste that the squamous metaplastic change of gallbladder eqithelium may be the histogenesis of gallbladder squamous cell carcinoma.

作者对正常胆囊、不同程度异型增生的胆囊,癌旁组织和胆囊癌共89例活检标本进行组织化学和免疫组织化学研究.正常胆囊只含硫酸粘液,无化生改变,而异型增生胆囊、癌旁组织和胆囊癌均见有胃肠上皮化生改变,且癌旁组织与各类异型增生的各类化生出现率间的差异无显著性(P>0.05)。在70例胆囊癌中47例有化生改变,分化程度越低,其出现率越低(P<0.01)。从轻度异型增生到癌,粘液含量逐渐减少,中性粘液和非硫酸粘液相对增多,硫酸粘液相应减少或消失,作者认为胆囊癌的发生与胆囊上皮化生有重要关系。用大分子角蛋白单克隆抗体K_(27)对部分异型增生胆囊上皮、鳞癌癌旁组织和部分鳞癌作免疫组织化学染色,显示细胞质内含有大分子角蛋增白,提示胆囊上皮的鳞状上皮化生,可能是胆囊鳞癌的组织来源。

The author applied an alkaline phosphatase-antialkaline phosphatase system with monoclonal antibodies to analyse the amount of T lymphocytes and its subpopulations in 40 cases of esophageal carcinoma, and observed the degree of stromal inflammatory cell reaction. The result showed that the lower the differentiation of cancer was, the fewer the infiltration of T_1 cells was. The lower differentiated tumors appeared to be accompanied with decrease in T_4 cells, relative increase in T_8 cells, and the fall of T_4/T_8...

The author applied an alkaline phosphatase-antialkaline phosphatase system with monoclonal antibodies to analyse the amount of T lymphocytes and its subpopulations in 40 cases of esophageal carcinoma, and observed the degree of stromal inflammatory cell reaction. The result showed that the lower the differentiation of cancer was, the fewer the infiltration of T_1 cells was. The lower differentiated tumors appeared to be accompanied with decrease in T_4 cells, relative increase in T_8 cells, and the fall of T_4/T_8 ratio. The more the lymphoid cell were, the more T_1 and T_4 cells were. But there was no rela- tionship between the degree of the stromal lymphoid cell infiltration and T_8 cells and T_4/T_8 ratio. It suggested that the simple counting and quantity of local lymphoid cells or lymphocytes was not substituted for detection T_4/T_8 ratio.

用单克隆抗体作碱性磷酸酶—抗碱性磷酸酶(简称APAAP)复合物免疫酶染色,定量分析食管鳞癌组织中浸润的T淋巴细胞及其亚群,同时观察炎细胞反应程度。结果发现,OKT_1(简称T_1)细胞的浸润密度随癌分化程度的降低而减少,分化差的癌组织内OKT_4(简称T_4)细胞减少,OKT_8(简称T_8)细胞相对增多,致T_4/T_8比值下降。间质淋巴样细胞多者,T_1和T_4细胞也相对较多,但T_8细胞及T_4/T_8比值与炎细胞反应程度无明显关系。提示不能以局部淋巴样细胞或T淋巴细胞的单纯计数和计量来代替检测T_4/T_8比值。

 
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