Experimental Study on Gene Therapy of Lumbar Intervertebral Disc Degeneration
Experimental Study on Mechanism of Lumbar Cartilage Endplate Degeneration
Experimental Research on Degeneration, Nutritional Pathway, Morphology, and Cell Apoprosis of the Intervertebral Disk
Baculoviruses as Vectors for Gene Therapy Reversing Intervertebral Disc Degeneration
Experimental Study on the Effect of LMP-1 in Intervertebral Disc Degeneration
It was 0.152±0.003,0.310±0.008, 0.262±0.014, respectively in the degenerative group.
② The percentage of positive cells in nucleus pulposus of intervertebral disc: The expression rate of Bcl-2 protein in normal group was (31.440±4.150)%, Bax (29.372±2.588)%, and in the degenerative group Bcl-2 was (18.239±2.470)%, Bax (52.349±3.764)%.
RESULTS: ① The apoptosis index (AI) in nucleus pulposus of intervertebral disc: It was 24.897±3.620 in normal group, 49.232±3.440 in the degenerative group.
However the patients with fracture had significantly more CFUs/ALP+ than those with degenerative disease (t=2.2793, P=0.0327), but not for the number of NCs (t=0.7600, P=0.4553).
Cervical disc degenerative disease are common medical conditoins treated by spine surgeons,wheras,intervertebral disc degeneration is archae-basis of pathology of Cervical disc degenerative disease.
颈椎退行性疾病(cervical disc degenerative disease，CDDD)是脊柱外科的常见病，而椎间盘 退变是CDDD的主要病理基础。
The results showed that OA kneepad could delay cataplasia of articular cartilage by inhibiting cytokines and adjusting biological effect of MMP-3,HA.
The Three-Dimensional Finite Element Study on the Influence of Cataplasia in the Adjacent Lumbar Segmenta After Different Lumbar Intervertebrae Fusion
Of the 48 articles, 19 articles were on chondrocytes cultured in vitro, 16 articles were on incidence of the knee ostarthritis and Chinese medicine preventing the articular cartilage cataplasia, and 13 articles were prospects and historical background of articular cartilage defects repaired by transplantation of chondrocytes.
2. Comparing foetus and adult cataplasia intervertebral disc cells in monolayer culture and three-dimension culture, measuring cell growth curve, cell inoculation
2、胎儿和成人 退变椎间盘细胞分别进行单层培养,其生长曲线,接种存活率、细胞增殖、细胞生长活性等指标检测结果示,胎儿椎间盘细胞各项指标均较成人 退变椎间盘细胞的表达为好,细胞生长快、增殖快、活性高。 提示成人椎间盘细胞的细胞功能发生 退变。
Skin necrosis,infection,the times for limbs restoration of functional training,the joints cataplasia and unsteadiness were the main complications which affect patient’s limb postoperative functions.
因近膝关节骨折手术创伤大 ,膝关节屈伸锻炼最早在手术 3天后进行。 ( 2 )术后感染、皮肤坏死、肢体恢复功能训练的时间、关节 退变和不稳是导致肢体功能不良的主要因素。
The degeneration of knee articular cartilage in groupⅡ was as serious as that in control groupⅠ(Hc=0 714 3, P =0 785).
(2 )实验组Ⅱ关节软骨 退变程度和对照组Ⅰ相比差异无显著性意义(Hc =0 714 3,P =0 785 )。
Results Intervertebral disc bulging in different le vel as a result from the degeneration of the disc was found in 148 cases( 90.24% ) out of 164. Disc protrusion was presented in 129 cases( 78.66% ) .
IL-1α may play an important role in the degeneration of cervical intervertebral discs.
结论 退变颈椎间盘中IL-1α的基因表达增强,且 退变越重,IL-1αmRNA表达越强,IL-1α可能在颈椎间盘 退变中发挥重要的作用。
BACKGROUND: Human transforming growth factor-β1 gene can be used for gene therapy of the degeneration of intervertebral discs, but the key to the experiment is to construct its effective vector.
CGRP and AChE are related to the degeneration of MEP;
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We prove that every Schubert variety ofG has a flat degeneration into a toric variety.
Their hepatopancreas were swollen and pale, accompanied by fatty degeneration, fatty necrosis of hepatocytes, and atrophy of the pancreas.
Kupffer cell hyperplasia, hepatic hydropic degeneration and ballooning degeneration were found in the 10th-20th days after infection.
Degeneration Effects in Distributed Systems and Their Behavior as Their Parameters Approach the Point of Degeneration
Both peptides prevent degeneration of Purkinje cells of rat cerebellar vermis upon chemical hypoxia induced by sodium azide in vivo; this effect is also observed on a behavioral level.
Despite individual differences, degenerative findings were decreased in hyperlipidemic rats given niacin and chromium.
Thus, they may be an ideal source of stem cells for treatment of inherited or degenerative diseases.
The thymus parenchyma was subject to degenerative changes such as the formation of gaps, hemorrhagic foci, and increased numbers of macrophages and mast cells.
Periodontal pathologies are inflammatory and degenerative diseases.
The low-lactate dehydrogenase (LDH) efflux indicated that the addition of the proteins we assayed to the culture medium prevented the development of degenerative processes caused by serum deprivation.
A detailed analysis of volatile constituents of Aquilegia pancicii Degen, a Serbian steno-endemic species
Chemical composition of the essential oil of Aquilegia pancicii Degen endemic to Serbia is reported.
Indocyanine green angiography-guided laser photocoagulation for occult choroidal neovascularization in age-related macular degen
Our data on BPA disposition in DA/Han rats are discussed in the context of other kinetic studies with BPA in pregnant rats, and in relation to the previous results from our laboratory ( Degen et?al.
Correlative radiological, self-assessment and clinical analysis of evolution in instrumented dorsal and lateral fusion for degen