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结肠癌细胞系     
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  colon cancer cell line
     Anti-tumor effect of combination of TRAIL and 5-Fu on colon cancer cell line SW480
     TRAIL与5-Fu合用对结肠癌细胞系SW480杀伤作用的研究
短句来源
     METHODS: Human breast cancer cell line MCF 7, human gastric cancer cell line BGC 823, human prostate cancer cell line DU 145, and human colon cancer cell line HT 29 were treated with 5 Aza CdR.
     方法:用5-Aza-CdR作用人乳腺癌细胞系MCF-7、人胃癌细胞系BGC-823、人的前列腺癌细胞系DU-145和人结肠癌细胞系HT-29。
短句来源
     Effect of NS-398 on in vitro invasion of colon cancer cell line HT-29
     NS-398降低结肠癌细胞系HT-29体外侵袭力
短句来源
     Effects of T-STAR gene on activity of telomerase in colon cancer cell line HCT-116
     T-STAR基因对结肠癌细胞系HCT-116端粒酶活性的影响
短句来源
     Methods Expression plasmid pcDNA3.1-DPC4 was constructed and transfected into the colon cancer cell line SW620 by use of lipofectamine gene transfer technique.
     方法 构建pcDNA3.1 DPC4真核表达质粒 ,利用脂质体转染技术将pcDNA3.1质粒和pcDNA3.1 DPC4质粒分别导入结肠癌细胞系SW6 2 0 ;
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  colon cancer cell lines
     Results The expression of COX-2 mRNA was not detectable in SW480 colon cancer cells. NS-398 (75 μmol/L) inhibited the cells proliferation and induced apoptosis in colon cancer cell lines. The ratio of cells in G1 phase was increased from 37.9% to 48.6 % , and the ratio of cells in S phase was decreased from 58.1% to 44.9%.
     结果结肠癌细胞系SW480中未检测到 COX-2 mRNA表达,NS-398(75 μmol/L)作用于SW480细胞72 h后,G1期细胞比率由37.9%上升至48.6%,S期细胞比率分别由58.1%,下降至44.9%,细胞增殖受抑制。
短句来源
     Objective To investigate the effects of histone acetylation on the expression of p21 WAF1 and p16 INK4A genes in two human colon cancer cell lines.
     目的 研究组蛋白乙酰化对Colo 32 0和SW1116人结肠癌细胞系p2 1WAF1和p16 INK4A基因表达的影响。
短句来源
     Methods Two colon cancer cell lines (SW1116 and Colo -320) were treated with the DNA methyltransferase (DNMT) inhibitor, 5-aza-2′-deoxycytidine (5-aza-dC) and/or the histone deacetylase (HDAC) inhibitor, trichostatin A(TSA)or sodium butyrate(NaBu).
     方法 培养人结肠癌细胞系SW1116和Colo 32 0 ,分别以去甲基化制剂 5 氮脱氧胞苷 (5 aza dC)和 /或组蛋白脱乙酰化酶 (HDAC)抑制剂曲古抑菌素 (TSA)及丁酸钠 (NaBu)干预细胞。
短句来源
     Two mutation hot spots (cDNA 709 718, 1931 1936) have been reported on human colon cancer cell lines.
     有报道表明 TGF- βR 基因的两个突变热点 ( c DNA70 9- 718,1931- 1936)在人类结肠癌细胞系有高的突变率。
短句来源
     Among 4 T lineage leukemia,5 neuroblastoma and 1 colon cancer cell lines tested, only Molt-3 was found weakly positive (31.40%) for 2B8a, while the remaining 3 T cell lines (Molt4, JM and CCRF-CEM), 5 neuroblastoma cell lines (LA-N1, KCNR, BE, SK-N-SH, SK-N-AS) and the colon cancer cell line (HR8348) tested were negative.
     在神经母细胞瘤细胞系SK-N-SH、KCNR、BE、LAN-1和SK-N-AS细胞以及结肠癌细胞系HR8348细胞上均不表达,而在羊膜细胞系FL细胞上呈一定的阳性表达,平均阳性细胞数为45.03%。
短句来源
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  colonic cancer cell lines
     Methods Two colonic cancer cell lines (SW1116 and Colo 320) were treated with the DNA methyltransferase (DNMT) inhibitor, 5 aza 2′ deoxycytidine (5 aza dC) or/and the histone deacetylase (HDAC) inhibitor, trichostatin A(TSA) or sodium butyrate.
     方法 培养 2种结肠癌细胞系SW 1 1 1 6和Colo 32 0 ,分别以去甲基化制剂 5 氮脱氧胞苷 (5 aza 2′ deoxycytidine ,5 aza dC)和 (或 )组蛋白脱乙酰化酶 (histonedeacetylase ,HDAC)抑制剂trichostatinA(TSA)及丁酸盐干预细胞。
短句来源
  colon carcinoma cell line
     Effect of NGX6 on Gene Expression Profile of Colon Carcinoma Cell Line HT-29
     NGX6对结肠癌细胞系HT-29基因表达谱的影响
短句来源
     Results: A genfibinib-resistant human colon carcinoma cell line HT-29/ZD has been established successfully, with the RI being 26.67. The doubling times of HT-29/ZD and HT-29 cells were 33.25 and 37.7 h, respectively.
     结果:建立了吉非替尼耐药的人结肠癌细胞系HT-29/ZD,其耐药指数RI为26.67,HT-29/ZD和HT-29的TD分别为33.25h和37.7h。
短句来源
     Establishment of gefitinib-resistant human colon carcinoma cell line HT-29/ZD and its drug resistant mechanism
     吉非替尼耐药人结肠癌细胞系HT-29/ZD的建立及其耐药机制探讨
短句来源
     Establishment of a Gefitinib-resistant Human Colon Carcinoma Cell Line HT-29/Gefitinib and Study of the Preliminary Resistant Mechanisms
     吉非替尼耐药人结肠癌细胞系HT-29/Gefitinib的建立及其耐药机制的初步探究
短句来源
     Objective To study the antitumor effects of RA538 on human colon carcinoma cell line HCT.
     目的 进一步研究RA538 对人结肠癌细胞系的生物学效应,选用介导RA538 重组体腺病毒,观察其对人结肠癌细胞系HCT 的作用。
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  colon cancer cell line
Objective: To study the expression of the inducible nitric oxide synthase (iNOS) gene and the effects of tumor necrosis factor- α (TNF-α) and interferon- γ (IFN-γ)on proliferation of the continuous cultured human colon cancer cell line CCL229.
      
Estradiol exhibited a concentration-dependent biphasic growth effect on a mouse colon cancer cell line (MC-26).
      
PAC1 is expressed on the HCT8 human colon cancer cell line and is coupled to the activation of both intracellular cAMP and Ca2+ with consequent stimulation of growth.
      
Both ELISA and fluorescence-activated cell sorting (FACS) reactions were inhibited with Fuc-GM1or H4-II-E but not with the structurally related ganglioside GM1 or Fuc-GM1-negative colon cancer cell line LS-C.
      
One of the CTL clones was able to kill an HLA-A2+ colon cancer cell line harbouring mutant TGFβRII.
      
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  colon cancer cell lines
Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
      
Expression of fas ligand in human colon cancer cell lines
      
Methods: A total of six human colon cancer cell lines were examined for the expression of Fas ligand mRNA and cell surface protein by using RT-PCR and flow cytometry respectively.
      
Conclusion: These data suggest that Fas ligand was expressed, at least in part, in human colon cancer cell lines and might facilitate to escape from immune surveillance of the host.
      
It was concluded that Ad-GRIM19 was successfully constructed and the overexpression of GRIM19 in colon cancer cell lines could promote the apoptotic cell death.
      
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  colonic cancer cell lines
Three colonic cancer cell lines (HT-29, Caco-2, and T84 cells) were studied.
      
Mevinolin caused a reduction in cholesterol synthesis in the colonic cancer cell lines, which was not further decreased by concurrent addition of LDL.
      
Three colonic cancer cell lines were used, two with neuroendocrine features (NCI-H716, LCC-18) and one (DLD-1) not known to have these features.
      
Employing blood group A- and A+ clones derived from the same parental colonic cancer cell lines, we studied the molecular mechanism of deletion/ reduction vs.
      
It was expressed both as a proand as an active form in tumours and colonic cancer cell lines.
      
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  colon carcinoma cell line
The effect of survivin siRNA on apoptosis, proliferation and invasion by a colon carcinoma cell line
      
Effects of meloxicam on vascular endothelial growth factor and angiopoietin-2 expression in colon carcinoma cell line HT-29
      
It is concluded that meloxicam can reduce the expression of VEGF and Ang-2 at the protein and mRNA level in colon carcinoma cell line.
      
In vitro effect of ciprofloxacin on HT-29 human colon carcinoma cell line: Assessment of cell proliferation by thymidine uptake
      
In an in vitro study, the effect of ciprofloxacin was examined on proliferation of HT-29 human colon carcinoma cell line.
      
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