Conclusions: It's very important for making the clinical use of antibiotic more reasonable to monitor the variation of bacteria spectrum and antibiotic resistance periodically.
Results:Nosocomial infection in intensive care unit was highest among gram-negative bacteria,espectically Pseudomonas aeruginosa(26.3%), Pseudomonas aeruginosa were the most prevalent isolates from ICU infections followed by Escherichia coil(18.1%), Klebsiella pneumoniae(15.0%), Entrobacter (14.6%), Acinetobacter spp(12.1%),Xanthomonas sp(9.8%).