失表达      negative expression(14) loss expression(20) lost expression(2) decreased expression(4) underexpression(1)   negative expression      Results The respectively negative expression rate of PTENmRNA was 55. 6%(extonl-8), 53. 3%(extonl-9), 55. 6% (exton5-8), 57.8%(exton5-9).      结果 在45例肿瘤组织中，PTENmRNA失表达率分别为57.8％(1-8)，55.6％(1-9)，55.6％(5-8)53.3％(5-9)。 短句来源      Results The negative expression of p16 was found in 62.5% (15/24) of the low differentiation grade and in 29.4% (5/17) of the high differentiation grade ( P =0.037).      结果　粘液表皮样癌中低分化组、高分化组的p16蛋白失表达率分别是 62 .5 % ( 15 / 2 4 )和 2 9.4 ( 5 / 17) ,P =0 .0 3 7; 短句来源      Conclusion:Overexpression of survivin and negative expression of P16INK4a in NSCLC indicated survivin and P16INK4a may play cooperative role in the tumorigenesis and development of NSCLC through inhibiting cancer cell apoptosis and promoting proliferation. So the expressions of Survivin and P16INK4a can be used as references for the diagnosis and prognosis of NSCLC.      结论:在NSCLC中survivin的过表达和P16INK4a的失表达提示二者可能通过抑制细胞凋亡和促进细胞增殖在非小细胞肺癌的发生发展中起协同作用,同时检测survivin、P16INK4a的表达状态对非小细胞肺癌的诊断和预后有一定的参考价值。 短句来源      The loss of TGFβ1's negative regulation in TCCs is related with the negative expression of TβRⅡ.      结论 :TGFβ1在TCCs的发生、发展过程中发挥双向调节作用 ,其负性调节作用的丧失与TβRⅡ失表达有关 ; 短句来源      Results The average negative expression rate of PTENmRNA in human glioma was 55.6%(25/45).      结果在45例肿瘤组织中,PTENmRNA平均失表达率为55.6%(25/45)。 短句来源 更多          loss expression      (3) DNA-PKcs positive rates in groups of first diagnosed, remission and contrast are 72.0%, 100% and 100%,loss expression rate of first diagnosed group is higher than the remission group and contrast group(P<0.05);      (3)DNA-PKcs在初诊组、缓解组和对照组阳性表达率分别为72.0％、100％和100％，初诊组失表达率与缓解组和对照组差别显著(P＜0.05)。 短句来源      In this group,loss expression rate of PTENmRNA is 40.0%,positive rate of hTERT is 84.0%,and loss expression rate of DNA-PKcs is 28.0%;      PTENmRNA失表达40．0％,hTERT阳性表达84．0％,DNA-PKcs失表达28．0％; 短句来源      Results: (1) PTENmRNA positive rates in groups of first diagnosed, remission and contrast are 60.0%,95.0% and 100%; loss expression rate of first diagnosed group is higher than the remission group and contrast group notably (P<0.05,P<0.01);      结果：(1)PTENmRNA在初诊组、缓解组和对照组阳性表达率分别为60.0％、95.0％和100％，初诊组失表达率显著高于缓解组和对照组(P＜0.05，P＜0.01)。 短句来源      Conclusion: The invasion and metastasis of large intestine carcinoma may be related to the low expression or loss expression of KAI1/CD82 gene.      结论 :大肠癌浸润和转移可能与KAI1 /CD82基因的低表达或失表达有关 短句来源      Results(1) The percentage of APC protein loss expression in colorectal adenocarcinomas (76.4%) was significantly greater than that in colorectal adenomas (27.3%) and normal colorectal mucosa tissues (13.3%)( P<0.05).      (1) APC基因蛋白产物在结直肠腺癌组织中失表达率(76.4％)明显高于结直肠腺瘤(27.3％)和正常粘膜组织(13.3％)，差别有显著性(P＜0.05)。 短句来源 更多          lost expression      \ Conclusion\ Lost expression of E cad and over expression of CD44V6 play an important role in the process of invasion and metastasis of colorectal cancer.      ④结论　E cad失表达和CD44V6高表达在结肠癌的浸润和转移过程中起重要作用 短句来源      [Conclusions]Lost expression of p15 and p16 are closely correlated with the process of carcinogenesis in MEC, probably the abnormality of the p16 gene is a direct factor.      [结论]p16、p15的失表达与黏液表皮样癌的发生和发展关系密切,p16基因的异常可能是更为直接的因素。 短句来源   decreased expression      Decreased expression of smad4 was helpful not only to enhance cell growth resistance to TGF-β1 but increase the invasion of oral squamous cell carcinoma.      smad4的失表达不仅有利于提高细胞对TGF-β1的生长抵抗,也增强了口腔鳞癌的侵袭性; 短句来源      decreased expression of TβRⅡ was helpful not only to enhance cell growth resistance to TGF-β_1 but increase the invasion of colorectal carcinoma.      TβRⅡ的失表达不仅有助于提高细胞对TGFβ1的生长抵抗,也增强了大肠癌的侵袭性。 短句来源      Decreased expression of TβRⅡ was helpful not only to enhance cell growth resistance to TGF-β1 but increase the invasion of colorectal carcinoma;      TβRⅡ的失表达不仅有助于提高细胞对TGFβ1的生长抵抗,也增强了大肠癌的侵袭性; 短句来源      Conclusion The expression of PTEN was seldom lost in pancreatic cancer,but reduced significantly in most malignant cases,suggesting the decreased expression of PTEN was closely related with occurrence and development of pancreatic cancer.      结论　胰腺癌中罕见PTEN蛋白失表达 ,但有低表达的趋势 ,提示PTEN在胰腺癌发生、演变中起着一定的作用。 短句来源     查询“失表达”译词为其他词的双语例句 underexpression   查询“失表达”译词为用户自定义的双语例句     我想查看译文中含有：的双语例句 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法，我们为您准备了出自英文原文的大量英语例句，供您参考。   negative expression Immuno-stain showed EGFR protein expression in the basal and bilateral membrane, and the cytoplasma in atrophic gastric gland, while negative expression was observed in normal gastric epithelial cells. 例句来源       Moreover, the 5-year survival rate in the E-cad-positive group was higher than in E-cad-negative group (P>amp;lt;0.01), and that in the CD44v6-positive group was lower than in the CD44v6-negative expression group (P>amp;lt;0.05). 例句来源       Positive expression of nm23-H1 combed with negative expression of erbB4 [nm23-H1(+)/erbB4(-)] predicted good prognosis for adenocarcinoma. 例句来源       There is no difference in postoperative survival time between patients with phospho-β-catenin positive expression and patients with negative expression, expression of phospho-β-catenin is not independent risk factor to prognosis. 例句来源       Mutation was detected in 16 of 20 cases of positive p53 expression, and another one was detected in 28 cases of negative expression cases. 例句来源       更多             loss expression The mode field and its leaky-mode-loss expression are given together with some numerical results which show that the influence of ellipticity is small compared with the effect of fiber anisotropy. 例句来源       Frequency of loss expression of DPC4 protein in various locations of biliary tract carcinoma 例句来源       To find the loss expression from the full loss model is a very complex and onerous job. 例句来源       The only difference between this unified goodwill loss expression and the one in Version-B is the time dependency of goodwill loss rate. 例句来源         lost expression Background: Decreased or lost expression of the cyclin-dependent kinase inhibitor p27kip1 protein has been found to be a poor prognostic factor in many cancers, including gastric cancer. 例句来源       Mutants that had lost expression of alleles of one or more HLA loci were isolated with immunoselection after γ-irradiation of a human lymphoblastoid cell line LCL 721. 例句来源       The ability to recover variants that have lost expression of male-specific antigen opens the possibility of their selection after mutagenesis. 例句来源       An immunoselected variant of the hybrid lacking both CEMR.3-derived copies of chromosome 6 lost expression of the HLA-B5 antigen encoded by 721.174 and expressed a decreased amount of HLA-A2. 例句来源       RJ 2.2.5 is a human B cell mutant, derived from Raji cells, which has lost expression of major histocompatibility complex (MHC) class II genes because of a defect in the AIR1 locus function. 例句来源       更多             decreased expression Four of 10 (40.0%) cases of primary GC showed absent or decreased expression of the FHIT protein as compared to their matched normal tissues. 例句来源       We have shown that the FHIT gene exhibits significantly decreased expression in human CRC compared to colorectal adenoma and normal colorectal tissue by tissue microarray (TMA). 例句来源       We show this decreased expression to be significantly correlated with the progression of colorectal carcinoma (P>amp;lt;0.05) as well as with differentiation and lymph node metastasis (P>amp;lt;0.05). 例句来源       Decreased expression of the human immunoglobulin J-chain gene in squamous cell cancer and adenocarcinoma of the lungs 例句来源       The reduced amount of AHLs in PAO1 was also correlated with decreased expression and production of several virulence factors such as elastase and pyocyanin. 例句来源       更多             其他          Archival specimens from transitional cell carcinoma of urinary bladder ( n =93) were studied immunohistochemically for expression of c erbB 2,H ras,P53 and Rb. The overexpression of c erbB 2,H ras,and P53 was seen in 26%,21%,and 48% of the tumors respectively, while the nonexpression of Rb was seen in 31% tumors.The majority (69%) have altered expression in one or more oncogenes, and/or antioncogenes with multiple altered expressions in 38%. The tumors with poorer differentiation ( P< 0.001),more ...             为探讨癌基因，抑癌基因在评估膀胱移行细胞癌预后中的意义，应用免疫组化法对９３例膀胱移行细胞癌组织中癌基因ｃｅｒｂＢ２、Ｈｒａｓ及抑癌基因Ｐ５３、Ｒｂ的表达产物进行检测。结果显示ｃｅｒｂＢ２、Ｈｒａｓ和Ｐ５３的表达率分别为２６％、２４％和４８％，Ｒｂ的失表达率为３１％。大多数（６９％）肿瘤有上述癌基因和（或）抑癌基因的表达异常，其中３８％的肿瘤同时有多个基因的表达异常，多基因表达异常与肿瘤的病理分级、临床分期、复发及５年生存率关系极为密切。提示肿瘤的多基因分析比单基因分析更有价值，多基因表达异常是判断膀胱移行细胞癌预后的一个可靠指标。 文摘来源          Objective\ To investigate the expression of p16 protein in pancreatic carcinoma and research the meaning of its expression.\ Methods\ Expression of p16 protein was studied immunohistochemically in 53 cases of pancreatic carcinoma,42 cases of benign pancreatic diseases and normal pancreatic tissue.\ Results\ The positive rate of p16 protein in pancreatic carcinoma(66.04%,35/53) was lower than in benign pancreatic diseases and in normal pancreatic tissue...             目的研究ｐ１６蛋白在胰腺癌组织中的表达情况，探讨其对胰腺癌的诊断、鉴别诊断及预后判断的意义。方法应用免疫组化法结合微波抗原修复法，对５３例胰腺癌和４２例胰腺良性病变及正常组织进行比较，观察ｐ１６蛋白的表达情况。使用Ｘ２检验及精确概率法分析组间差异，采用Ｋａｐａｎ－ｍｅｉｒｅ寿命及Ｌｏｇｅｒａｎｋ检验，分析组间生存率差异。结果（１）胰腺癌组织中ｐ１６蛋白阳性率为６６．０４％（３５／５３），胰腺良性病变及正常组织的阳性率为８５．７１％（３６／４２），两者差异有显著性（Ｐ＜０．０５）；（２）ｐ１６蛋白的表达强度与胰腺癌的组织学分化、临床病理分期及术后生存期密切相关；（３）ｐ１６蛋白的失表达可能发生在胰腺癌发生发展过程中较晚期阶段。结论ｐ１６蛋白是胰腺癌患者预后判断的一个重要指标，即ｐ１６蛋白表达阳性者预后较好。 文摘来源          Objective: The expression of nm23 gene product/NDPK was found to be inversely correlated to the progression of gastric and colorectal carcinomas in our previous studies. The purpose of this study was to evaluate the relationship between nm23/NDPK expression and nuclear DNA content in gastric and colorectal carcinomas. Method: 33 gastric carcinoma specimens and 24 colorectal carcinoma specimens with various intensity of nm23/NDPK expression were obtained. The nuclear DNA contents and ploidy patterns were ana...             探讨ｎｍ２３基因产物／ＮＤＰＫ表达与胃癌、大肠癌细胞核ＤＮＡ含量的关系。方法：ｎｍ２３基因产物／ＮＤＰＫ表达阴性、弱阳性及强阳性的胃癌、大肠癌共５７例（胃癌各１１例、大肠癌各８例），使用ＤＮＡ图像分析技术检测癌细胞核ＤＮＡ含量。结果：ｎｍ２３／ＮＤＰＫ表达阴性的胃癌或大肠癌细胞核ＤＮＡ含量显著高于ｎｍ２３／ＮＤＰＫ阳性表达者（分别为Ｐ＜００５，Ｐ＜０００１）；在ＤＮＡ倍体分布形式上，ｎｍ２３／ＮＤＰＫ阴性的胃癌和大肠癌中二倍体细胞的检出率较低（分别为Ｐ＜００５、Ｐ＜０００１）；而非整倍体细胞检出率则显著高于ｎｍ２３／ＮＤＰＫ阳性表达者（分别为Ｐ＜００５、Ｐ＜０００１）；结论：ｎｍ２３基因产物／ＮＤＰＫ失表达与胃癌、大肠癌非整倍体细胞形成有关。 文摘来源   << 更多相关文摘         相关查询: 表达 表达表达 表达( 失 中性表达 叙事表达 部分表达 opgmrna表达 心理表达 表达主题 表达重组子 动作表达  对查询结果不满意

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