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   胰腺癌 在 基础医学 分类中 的翻译结果: 查询用时:0.863秒
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胰腺癌
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  pancreatic cancer
    LOSS OF HETEROZYGOSITY MICROSATELLITE DNA ON CHROMOSOME LOCI 3,5,7,9 AND 18 IN HUMAN PANCREATIC CANCER
    人胰腺癌组织3、5、7、9和18号染色体部分位点的杂合性丢失
短句来源
    Methods Analysing loss of heterzygosity (LOH) of microsatellite DNA on chromosome loci 3,5,7,9 and 18 with PCR SSLP silver stain method in pancreatic cancer.
    方法选择来自3、5、7、9和18号染色体不同位置的9对多态性引物,对45例胰腺癌存档石蜡标本经显微镜下剥离后,以PCR-SSLP-银染法检测胰腺癌中这些位点的杂合性丢失。
短句来源
    ③Applications in therapy of quantum medicine, such as nasopharyngeal cancer, pancreatic cancer etc, these acquired a certain therapeutic effect.
    ③量子医学在治疗方面的应用 ,对鼻咽癌、胰腺癌等患者进行治疗 ,取得了一定的疗效。
短句来源
    According to the report of China's Disease Surveillance Point System, pancreatic cancer accounted for 2.26% of all deaths due to tumor in 2000, with the 6-8~(th) rank for men and the 9-10~(th) rank for women.
    胰腺癌是恶性程度最高预后最差的肿瘤之一,居我国肿瘤死因顺位的6-8位(男性)和9-10位(女性)。
短句来源
    The metabolite profiles from rat hepatic fibrosis, nude mouse model of human pancreatic cancer and rat chronic pancreatitis were investigated using high-resolution magic-angle spinning ~1H nuclear magnetic resonance (HR-MAS NMR) and principal component analysis (PCA) on intact tissue.
    本文利用高分辨魔角旋转核磁共振技术(HR-MAS NMR)与主成分分析法(PCA)相结合分别对大鼠肝脏纤维化病变模型、人胰腺癌荷瘤裸小鼠模型以及大鼠慢性胰腺炎模型的代谢产物特征进行了研究。
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  pancreatic carcinoma
    Detection of pancreatic cancer-associated antigen PCA2 in serum was performed by ELISA binding inhibition test using monoclonal antibody PCA2 in 31 patients with pancreatic carcinoma, 17 with acute pancreatitis,8 with chronic pancreatitis and 50 healthy individuals.
    应用建立的单克隆抗体PCA_2的ELISA结合抑制法对50名正常人,31例经手术病理证实的胰腺癌,17例急性胰腺炎和8例慢性胰腺炎进行检测。
短句来源
    The serum level of PCA2 antigen was significantly higher in patients with pancreatic carcinoma than in healthy controls (P<0.001).
    结果表明,单抗PCA_2所对应的抗原(PCA_2-Ag)在胰腺癌患者血清中的平均含量显著高于正常对照组(P<0.001)。
短句来源
    The combined detection with PCA2 antigen,CA19-9 and CEA assays can improve the accuracy of diagnosis of pancreatic carcinoma and PCA2 antigen is a promising tumor marker providing useful information for its diagnosis.
    PCA_2-Ag与CA19-9、CEA联合检测可提高胰腺癌的正确诊断率。 PCA_2-Ag的检测对胰腺癌具有一定的诊断价值。
短句来源
  “胰腺癌”译为未确定词的双语例句
    ESTABLISHMENT OF MONOCLONAL ANTIBODY AGAINST PANCREATIC CARCINOMA
    抗人胰腺癌单克隆抗体杂交瘤的建立
短句来源
    Recently, GnRH and its receptor have been found exist in many extra-hypothalamus-pituitary tissues, such as gonad (ovary, oviducU prostate,testis,placenta > et al. ) and immune system ( T and B lymphocytes ).
    近二十年的大量研究证据表明,GnRH及其受体广泛存在于下丘脑-垂体轴之外,如生殖系统(卵巢、输卵管、前列腺、睾丸以及胎盘等)、免疫系统(T、B淋巴细胞)和许多恶性肿瘤(如乳腺癌、肺癌、胰腺癌及肝癌),通过自分泌和旁分泌途径对这些组织器官以及恶性肿瘤的生长起调节作用。
短句来源
    Background and Objective: The application of the technique of high-intensity focused ultrasound (HIFU) to treat the malignant tumor (especially deep malignant tumor) has gained notable clinical effects.
    前期研究已证明高强度聚焦超声(high-intensity focused ultrasound,HIFU)辐照对1.1mm的动脉会产生损伤。 由于临床诊断的肿瘤病人中老年人居多,根据临床资料提示:肝癌、胰腺癌等腹腔恶性肿瘤,中老年患者占68.97%,常常伴有高脂血症或动脉粥样硬化(atherosclerosis,AS)。
短句来源
    Normal mucosa of digestive tract secretes a small quantity of CEA.
    CEA在正常消化道黏膜仅少量分泌,而90%的消化道恶性肿瘤、胰腺癌,70%非小细胞肺癌和50%乳腺癌有CEA的高表达,故CEA可作为这些肿瘤检测和治疗的靶分子。
短句来源
    This study demonstrated that vitamin A had prevention, inhibition and reversal effects on cancerous lesions induced by MNNG.
    本实验从不同方面证实了维生素A在实验性胰腺癌中的化学预防作用,为维生素A在胰腺癌防治领域中的应用奠定了实验基础。
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  pancreatic cancer
Inhibitive Effect of Prodigiosin on the Proliferation of Human Malignant Pancreatic Cancer Cells
      
Pancreatic cancer is not only common, but also extremely difficult to treat, for which it has been called "the challenge of the twenty-first century".
      
In this study, we find that prodigiosin could effectively inhibit the proliferation of human pancreatic cancer cells H8898 in a dose-and-time-dependent manner, with an IC50 of 75μmol according to the results of MTT and cell proliferation assays.
      
Prodigiosin also could induce apoptosis of pancreatic cancer cells at low concentration and results in the fragmentation pattern of DNA.
      
All these results demonstrate that prodigiosin can obviously inhibit the proliferation of pancreatic cancer cells H8898 by arresting the cell cycle and inducing apoptosis.
      
更多          
  pancreatic carcinoma
Immunotherapeutic effects on murine pancreatic carcinoma by β-elemene combined with dendritic cells modified with genes encoding
      
It is totally different from pancreatic carcinoma in epidemiology, histology, pathology and prognosis.
      
Adjuvant and Neoadjuvant Radiochemotherapy in Ductal Pancreatic Carcinoma
      
Ductal pancreatic carcinoma ranks third among malignancies of the gastrointestinal tract and its incidence is rising.
      
Chemoradiation of Unresectable Pancreatic Carcinoma: Impact of Pretreatment Hemoglobin Level on Patterns of Failure
      
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A hybridoma cell line have been established which can produce monoclonalantibody against human pancreatic carcinomas by the way of fusion of SP2/0 myeloma cell and the spleen cells from Balb/C mice which has beenimmuned with fresh carcinoma tissues. By the study of indirect fluresentmethod and thssue immunochemical method, the resuit showed the monoclonalantiboby specifically reacted with human pancreatic carcinoma cells but notwith examined normol human tissues and fetal tissues.

用小鼠骨髓瘤细胞系SP 2/0与新鲜癌组织匀浆免疫的Balb/C小鼠脾细胞融合制备抗人胰腺癌单克隆抗体。经间接荧光抗体法和免疫组织化学法筛选及有限稀释法克隆化后,获得一株产生与正常人体组织不反应,与人胰腺癌反应率高的抗人胰腺癌单克隆抗体的杂交瘤细胞株。

We used SDS-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting of monoclonal antibody (McAb) J28 and peanutagglutinin (PNA) for detecting fetoacinar pancreatic protein (FAP) in extracts of 20 cases of fetal pancreas, 5 of pancreatic cancer and 4 of normal pancreas. The result showed that fetal pancreas and pancreatic cancer had a same level band about 110000 in Commassie blue stain, but absent in normal pancreas. The band could react with both McAb J28 and PNA PNA also could react with smaller glycoprotein...

We used SDS-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting of monoclonal antibody (McAb) J28 and peanutagglutinin (PNA) for detecting fetoacinar pancreatic protein (FAP) in extracts of 20 cases of fetal pancreas, 5 of pancreatic cancer and 4 of normal pancreas. The result showed that fetal pancreas and pancreatic cancer had a same level band about 110000 in Commassie blue stain, but absent in normal pancreas. The band could react with both McAb J28 and PNA PNA also could react with smaller glycoprotein in pencreatic cancer. It is suggested that McAb J28 and PNA combine with different sites of FAP.

20例胚胎胰腺、5例胰腺癌、4例正常胰腺提取物行聚丙烯酰胺凝胶电泳(SDS-PAGE)、单克隆抗体J28免疫印渍和花生凝集素印渍,结果发现考马斯亮蓝染色后胚胎胰腺和胰腺癌提取物有一相同条带,分子量约为110000,这一条带即是胚胰腺泡蛋白(FAP,它可与单克隆抗体J28和花生凝集素结合,正常胰腺无此条带。花生凝集素还可以和胰腺癌组织中分子量更小的糖蛋白结合,说明FAP分子上有单克隆抗体J28和花生凝集素的不同位点。

Bovine pancreatic ducts were organ-cultured in the presence of MNNG for up to 8 weeks. Under light and transmission electron microscopic observasion, epithelial cells developed aplastic hyperplasia and cancerous changes. Ag-NOR granule count indicated that nuclear organizer region protein increased obviously. When pancreatic duct explants were treated simultaneously with MNNG and vitamin A, epithelial cells did not develop hyperplasia and cancerous changes, and always keeping simple columnar epithelium in 8...

Bovine pancreatic ducts were organ-cultured in the presence of MNNG for up to 8 weeks. Under light and transmission electron microscopic observasion, epithelial cells developed aplastic hyperplasia and cancerous changes. Ag-NOR granule count indicated that nuclear organizer region protein increased obviously. When pancreatic duct explants were treated simultaneously with MNNG and vitamin A, epithelial cells did not develop hyperplasia and cancerous changes, and always keeping simple columnar epithelium in 8 weeks. The nuclear orgonizer region protein had no change. In order to investigate reversal effects of vitamin A, culture were treated with MNNG and without vitamin A for 4 weeks, in continuous 4 weeks some explants were incubated in control medium, others were cultured with vitamin A and without MNNG. In the former we saw the similar lesions to MNNG group, but in the later group the hyperplasia were reversed. This study demonstrated that vitamin A had prevention, inhibition and reversal effects on cancerous lesions induced by MNNG.

应用化学致癌物MNNG作用于体外培养牛胰管上皮,8周时,电镜下观察牛胰管上皮在形态学上发生了明显的异型增生和早期癌样改变;而加入维生素A组上皮细胞仍保持单层柱状上皮。如先加入MNNG培养4周,造成牛胰管上皮细胞的明显增生,停用MNNG,加维生素A继续培养4周,发现可遏制并逆转增生的复层细胞,使之基本恢复为单层柱状上皮;而未加维生素A的相应对照组却出现了癌样增生。本实验从不同方面证实了维生素A在实验性胰腺癌中的化学预防作用,为维生素A在胰腺癌防治领域中的应用奠定了实验基础。

 
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