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骨诱导作用
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  bone induction
     Bone Induction by Human Periodontal Ligament Fibroblasts Transfected with Bone Morphogenetic Protein 2 Gene
     骨形成蛋白2基因转染的人牙周膜成纤维细胞的骨诱导作用
短句来源
     The partially purified rhBMP6 by heparin affinity chromatography was shown to possess bone induction activity tested by the induction of alkaline phosphatase activity in C2C12 cells.
     将表达产物rhBMP6初步纯化后,能诱导前成肌细胞系C2C12向成骨细胞方向转化,显示其具有骨诱导作用
短句来源
     Conclusion CCHA has good biocompatibility and bone induction.
     结论CCHA具有良好的生物相容性和骨诱导作用
短句来源
     Objective To observe in vitro the effects of platelet-rich plasma ( PRP) of different concentrations on the proliferation, differentiation, and mRNA of autologous bone marrow stromal cells(MSCs), to evaluate the bone induction effect of PRP on MSCs, and to investigate the feasibility of bone tissue regeneration by tissue engineering with the obtained optimal concentration.
     目的:体外观察不同浓度犬富血小板血浆(PRP)对自体骨髓间充质细胞(MSCs)增殖、分化和mRNA表达的影响,初步评估PRP对MSCs的骨诱导作用,并得到最佳使用浓度,探讨组织工程学方法用于骨组织再生的可行性。
短句来源
     CONCLUSION:Both of two materials have good biocompatibility. Bionic biphasic ceramic-like biologic active bone has heterogenous ossification ability and bionic BCBB is ineffective in bone induction.
     结论:两种材料肌袋植入后生物相容性好,仿生双相陶瓷生物活性骨具有异位成骨能力,仿生双相陶瓷生物骨无骨诱导作用
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  bone inductive effect
     Conclusion Bone at the interface can grow into the contained space of hollow prosthesis through holes at the wall, and form mature bone. rhBMP-2 loaded in the hollow space can obviously promote this effect and the carrier Healon GV has no negative influence but can increase bone inductive effect.
     结论界面骨质可通过孔洞长入中空金属植入物的空腔内并形成成熟的骨质,rhBMP-2可促进骨长入效应及成骨质量,rhBMP-2载体HealonGV不影响且可增强骨诱导作用
短句来源
  “骨诱导作用”译为未确定词的双语例句
     Osteogenic protein-1(OP-1),also referred to as bone morphogenetic protein-7(BMP-7),has the effective osteoinduction.
     成骨蛋白-1(OP-1)又称骨形态发生蛋白-7(BMP-7),具有高效的骨诱导作用
短句来源
     Conclusion: β-TCP/rhBMP-2 possesses osteoinductive potential.
     结论:可降解多孔β-TCP/rhBMP-2具有良好的骨诱导作用
短句来源
     ②BMP has the powerful bone-induced effect and it is the main model of bone regeneration.
     ②BM P具有强大的骨诱导作用,在膜内植入复合BM P的CPC后,诱导成骨成为骨再生的主要形式。
短句来源
     OBJECTIVE: To determine the osteoinduction effect of demineralized dentin matrix (DDM) and feasibility of clinical application.
     目的:证明脱矿人牙基质(DemineralizedDentinMatrix,DDM)具有良好的骨诱导作用,对DDM临床应用的可行性作出客观评价。
短句来源
     Conclusions The bone density of experimental group increasing by degrees demonstrated the effect of grafts in bone tissueengineering.
     结论实验侧的骨密度系数是呈递增式上升,论证本支架材料在组织工程骨构建中的骨诱导作用
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  bone induction
Treatment of DABM with the cyanoacrylate caused an intense inflammatory process with a foreign body reaction, and abolished bone induction and new bone formation.
      
Bone induction by both isograft and homograft of the mouse calvaria was observed in the diffusion chambers using HA millipore filter.
      
Bone induction by implantation of decalcified bone is described by many authors.
      
The role of periosteal bone induction was essential for the ossification of a growing gap, whereas the ossification of a simple gap proceeded equally by the endosteal and periosteal routes.
      
The rationale underlying this intralesional treatment was that the bone grafting material might reverse ABC expansion by promoting ossification through a bone induction mechanism.
      
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Using decalcified bone matrix (DBM), bone matrix gelatin (BMG) and Undecalcified bone matrix(UDBM), the capacity of bone induction -was investigated respectively.the experiments were done on the adult rat skulls on which trephine defects of 8 mm in diameter were made, the implants were in form of discs of same size as the defects. BMG was found having the best bone induction capacity, while DBM the next, from the histo-pathological observation, it was suggested that during the process of resorption of BMG and...

Using decalcified bone matrix (DBM), bone matrix gelatin (BMG) and Undecalcified bone matrix(UDBM), the capacity of bone induction -was investigated respectively.the experiments were done on the adult rat skulls on which trephine defects of 8 mm in diameter were made, the implants were in form of discs of same size as the defects. BMG was found having the best bone induction capacity, while DBM the next, from the histo-pathological observation, it was suggested that during the process of resorption of BMG and DBM, bone morphogenetic Protein (BMP) was released by diffusion, which induced mesenchymal cells originating from the dura mater to differentiate into osteoblasts and form new bone repairing the bone defects

本文报告一组促进骨折愈合的实验结果,所用试验材料为骨基质明胶片、脱钙骨片和不脱钙骨片。在大鼠颅顶骨上制成8mm直径的圆形骨缺损,作为骨折不连接的动物模型。在此骨缺损内分别植入上述三种材料。结果表明它们都有不同程度的骨诱导作用,其中骨基质明胶片的骨诱导作用最强,脱钙骨片次之。病理组织学观察显示植入片在吸收的同时释放出骨形成性蛋白,诱发来源于硬脑膜的间充质细胞分化为成骨细胞,形成新生骨组织,修复骨缺损

Fifty four healthy rabbits with 108 limbs were divided into 3 grops with 36 limbs in each group, made 1 cm long radius defect in each limb. Group A was implanted by decalcified homogenous bone; roup B by fresh autogenous bone and group C by fresh homogenous bone. Then 3 rabbits with 6 limbs of each group were killed in the 1st, 3, 5, 7, 10 and 13th week respectively, to compare the bone healing roentgenologically and histologically There was receptive reaction in fresh homogenous bone implantation but not demonstrated...

Fifty four healthy rabbits with 108 limbs were divided into 3 grops with 36 limbs in each group, made 1 cm long radius defect in each limb. Group A was implanted by decalcified homogenous bone; roup B by fresh autogenous bone and group C by fresh homogenous bone. Then 3 rabbits with 6 limbs of each group were killed in the 1st, 3, 5, 7, 10 and 13th week respectively, to compare the bone healing roentgenologically and histologically There was receptive reaction in fresh homogenous bone implantation but not demonstrated in decalcified homogenous bone implantation. This experiment indicated that the bone healing of implantation with decalcified homogenous bone and fresh autogenous bone were faster than fresh homogenous bone and no receptive reaction. However there was no significant difference in the bone healing between the implantation with decalcified homogenous bone and fresh autogenous bone. The new cartilage and new bone appeared in the decalcified implant rather than near the host bone. This shows that the new bone is formed probablly by bone induction. Decalcified homogenous bone is a better implant.

在54只兔的108例桡骨上分别造成1cm的骨缺损,将其平分为三组,分别植入脱钙同种异体骨、新鲜自体骨和新鲜同种异体骨。并于第1、3、5、7、10和13周,每组杀3只兔,用X线照片及组织学切片观察骨的愈合情况。结果发现新鲜异体骨植入后有排斥反应,而脱钙异体骨植入无此反应。实验证明脱钙同种异体骨是一种较好的植入物。彼优于新鲜异体骨,与新鲜自体骨植入无显著差异。新骨及软骨出现在植入物中而不在邻近宿主骨处,表明新骨形成可能是骨诱导作用的结果。

Sheep bone morphogenetic protein (sBMP) was chemically extracted from demineralized and gelatinized cortical bone by means of a CaCl_2-urea solvent, sBMP was isolated in quantity of 1,250mg/kg fresh bone. 5mg of the isolated protein implanted in muscle pouches of rats induced perivascular mesenchymal connective tissue cells which differentiated into cartilage by the 7th day and calcifying new bone by 21st day.

本文报道羊成骨蛋白(sBMP)的提取方法及其生物学活性试验结果。小鼠大腿肌肉内种植5mg sBMP后7天,局部形成软骨组织,14天形成骨样组织,28天出现板层骨结构。sBMP的骨诱导作用主要在于促使纤维母样间充质细胞定向分化成为软骨细胞和骨母细胞进而形成骨组织。文内还讨论了sBMP提取的有关问题及其对靶细胞作用的机制等问题。

 
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