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  promoting
     Experimental Study of The Effect of Promoting Apoptosis of Vascular Smooth Muscle Cell with Human Bcl-2 mRNA-cleaving Ribozyme
     切割人bcl-2mRNA核酶对血管平滑肌细胞凋亡作用的实验研究
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     Study on a Fined Selective Small Prescription Gushudan Promoting Osteoblastic Bone Formation
     中药精选小复方骨疏丹成骨细胞骨形成作用的研究
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     Expression of Nuclear Factor κB in Breast Cancer and Its Role in Promoting Cancer Metastasis Discipline of Oncology
     核因子κB在乳腺癌中的表达和转移作用
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     Establishment of Murine Interstitial Cells of Cajal Loss Model and Study on SCF Promoting Its Restoration
     小鼠小肠Cajal间质细胞缺失模型的建立及SCF其恢复研究
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     The Effect of Promoting Apoptosis of Human Cholangiocarcinoma Cells with bcl-2 mRNA-cleaving Ribozyme
     切割bcl-2 mRNA核酶对人胆管癌细胞的凋亡作用
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  promote
     The optimal concentration of JDP N to promote secretion of IL 1 was 50μg/ml and 100μg/ml for that of TNF α and NO.
     JDPN最佳诱导浓度对进MΦ分泌IL1为50μg/ml,TNFα分泌为100μg/ml。
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     【Conclusion】Ag85B/IL-2 fusion protein may promote the proliferation of human PBMC and Th1 type cytokine IL-12 and IFN-γ secretion.
     【结论】Ag85B/IL-2融合蛋白具有人PBMC增殖和Th1型细胞因子分泌的作用。
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     Result Apoptosis rate increased with the increase of [Ca~ 2+ ]i which shows an obvious function to promote apoptosis,r_24 =0.9001(P=0.0145); r48=0.9343(P=0.0063).
     结果胞外Ca2+作用于HL-60细胞244、8 h后发现对辐射诱导细胞凋亡随Ca2+浓度的增加细胞凋亡率增大,Ca2+有明显的凋亡作用,相关性很好r24=0.9001(P=0.0145),r48=0.9343(P=0.0063)。
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     CONCLUSION:The optimum dose of polysaccharide parts was IP-Ⅸ(0.125mg·mL-1)and IP-Ⅻ(0.125mg·mL-1),which can promote the proliferation of lymphocyte.
     结论板蓝根多糖对淋巴细胞的增殖作用的最适剂量为IP-Ⅸ(0.125mg.mL-1)和IP-Ⅻ(0.125mg.mL-1)。
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     The optimal pH is at 6.0~7.0 and temperature 40℃, the optimal concentration of substrate is 1.0%~1.2%,addition of Ca2+ will greatly promote the enzyme activity,whereas Fe3+, Mn2+, Cu2+ and Hg2+ cause inhibition.
     该酶作用的最适pH为6.0~7.0,最适温度为40℃,最适底物浓度为1.0%~1.2%,Ca2+离子的添加对酶反应有较强的进作用,而Fe3+、Mn2+、Cu2+和Hg2+等离子有不同程度的抑制作用。
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     Effects and Mechanism of Active Site from Reimforcing Kidney Chinese Herbs on Bone Formation
     补肾中药醇提活性部位成骨作用及机制
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     Interaction between Chaperone and Interleukin-2 Proliferation Signaling--Functional Study of Signal Molecule Chaperone Hsp90
     分子伴侣与白细胞介素-2增殖信号通路的相互作用——信号分子伴侣Hsp90功能研究
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     Study of the Role of GJB1、GAD、GIRK1 in Self-acceleration and Self-protection Mechanisms in the Hippocampus of Temporal Lobe Epilepsy Rat
     GJB1、GAD、GIRK1在颞叶癫痫大鼠海马内源性痫与抗痫机制中作用的研究
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     Targeted in Vitro and in Vivo Tumor Suppression by a Secreted Fusion Protein Consisting of Anti-erbB2 Antibody and Reversed Caspase-3
     抗erbB2单链抗体和重构型caspase-3融合蛋白的分泌表达及其体内、外靶向凋亡作用
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     The Change of Cytokines and Nuclear Factor-kappa B in Lung Tissue of LPS-induced Acute Lung Injury in Neonatal Rats: The Effect of N-acetylcysteine
     LPS致新生大鼠急性肺损伤炎性细胞因子、抗炎性细胞因子和NF-κB变化及N-乙酰半胱氨酸干预作用的研究
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  promoting
While the influence of thiol amino acid on promoting dissolution remains relatively low.
      
Adipokine resistin exerted a direct effect in promoting HUVEC dysfunction by promoting ICAM-1 and ET-1 expression.
      
The aim of this research was to investigate the effects of modafinil, a new wake-promoting agent, on vestibular function during 24 h sleep deprivation (SD) so as to provide experimental evidence for the rational use of this drug among air crew.
      
Combinations of biocides with salts promoting steel passivation (such as carbonates and phosphates) have been developed, which are more potent in decreasing corrosion-induced losses of mild steel than biocides and salts taken in isolation.
      
Data on glutamine synthetase (GS) of Azospirillum brasilense, a plant growth-promoting rhizobacterium, have been reviewed.
      
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  promote
Prodigiosin may effectively enter cells and promote the level of intracellular reactive oxygen species (ROSin) in a dose-dependent manner.
      
One type is the threshold concentration that can promote algae growth, and its value is between 10 and 1 nmol level, or even lower.
      
The results indicate that the infection delay will promote the epidemic outbreaks, increase the prevalence and reduce the critical threshold of epidemic spreading.
      
Fourth, efficient measures should be taken to stop human activities that are harmful to Metasequoia and to improve the environment of ONMMT in order to promote the protection of the ONMMT population and its ecosystem.
      
To promote afforestation in sandy lands and increase the effects of prevention and control of desertification, the application of a new drought-resistant product-solid water and foliar fertilizer "Shifengle"-was studied.
      
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By means of Friedel-Crafts reaction, the following compounds were prepared from 4-methyl- imidazolone-2 and four different ω-carbethoxy acyl halides: 4-methyl-5-(δ-carbethoxy-γ-methyl- butyryl)-imidazolone-2, 4-methyl-5-(δ-carbethoxy-γ, γ-dimethylbutyryl)-imidazolone-2, 4-methyl- 5-(ω-carbethoxy-n-nonanoyl)-imidflzolone-2, and 4-methyl-5-(ω-carbethoxy-n-heptadecanoyl)- imidazolone-2. With PtO_2 as catalyst, they were readily reduced to the four corresponding imidazolidone compounds. These compounds were hydrolyzed...

By means of Friedel-Crafts reaction, the following compounds were prepared from 4-methyl- imidazolone-2 and four different ω-carbethoxy acyl halides: 4-methyl-5-(δ-carbethoxy-γ-methyl- butyryl)-imidazolone-2, 4-methyl-5-(δ-carbethoxy-γ, γ-dimethylbutyryl)-imidazolone-2, 4-methyl- 5-(ω-carbethoxy-n-nonanoyl)-imidflzolone-2, and 4-methyl-5-(ω-carbethoxy-n-heptadecanoyl)- imidazolone-2. With PtO_2 as catalyst, they were readily reduced to the four corresponding imidazolidone compounds. These compounds were hydrolyzed with 1 N NaOH and then followed by acidification to give the following acids: 4-methyl-5-(δ-carboxy-y-methylbutyl)- imidazolidone-2, 4-methyl-5-(δ-carboxy-γ, γ-dimethylbutyl)-imidazolidone-2, 4-methyl-5-(ω-car-boxy-n-nonanyl)- imidazolidone-2, and 4-methyl-5-(ω-carboxy-n-heptadecanyl)-imidazolidone-2. Microbiological tests indicated that the first three acids are good anti-biotins towards lactobacillus casei and saccharomyces cerevisiae strain No. 139. Due to its extreme insolubility in water, the last compound has not yet been tested for its microbiological activity.

(1)利用Friedel-Crafts反應,由4-甲基-2-氧代-二氫化咪唑及四個不同的醯氯羧酸酯,得到下列四個化合物:4-甲基-5-(δ-乙氧羰基-γ-甲基丁醯)-2-氧代-二氫化咪唑,4-甲基-5-(δ-乙氧羰基-γ,γ-二甲基丁醯)-2-氧代-二氫化咪唑,4-甲基-5-(ω-乙氧羰基-正壬醯)-2-氧代-二氫化咪唑及4-甲基-5-(ω-乙氧羰基-正十七醯)-2-氧代-二氫化咪唑。 (2)用Cr_(2)O_3精製過的乙酸爲溶劑,PtO_2爲觸媒,這四個4-甲基-2-氧代-二氫化咪唑的衍生物,很順利的吸收相當於3分子的氫,還原為相對應的4-甲基-2-氧代-四氫化咪唑的衍生物,水解後得到下列四個酸:4-甲基-5-(δ-羧基-γ-甲基丁基)-2-氧代-四氫化咪唑,4-甲基-5-(δ-羧基-γ,γ-二甲基丁基)-2-氧代-四氫化咪唑,4-甲基-5-(ω-羧基-正壬基)-2-氧代-四氫化咪唑及4-甲基-5-(ω-羧基-正十七基)-2-氧代-四氫化咪唑。前三者已作過初步的微生物效應試驗,對於lactobacillus casei及saccharomyces cerevisiae都有顯著的反生素效應。第四...

(1)利用Friedel-Crafts反應,由4-甲基-2-氧代-二氫化咪唑及四個不同的醯氯羧酸酯,得到下列四個化合物:4-甲基-5-(δ-乙氧羰基-γ-甲基丁醯)-2-氧代-二氫化咪唑,4-甲基-5-(δ-乙氧羰基-γ,γ-二甲基丁醯)-2-氧代-二氫化咪唑,4-甲基-5-(ω-乙氧羰基-正壬醯)-2-氧代-二氫化咪唑及4-甲基-5-(ω-乙氧羰基-正十七醯)-2-氧代-二氫化咪唑。 (2)用Cr_(2)O_3精製過的乙酸爲溶劑,PtO_2爲觸媒,這四個4-甲基-2-氧代-二氫化咪唑的衍生物,很順利的吸收相當於3分子的氫,還原為相對應的4-甲基-2-氧代-四氫化咪唑的衍生物,水解後得到下列四個酸:4-甲基-5-(δ-羧基-γ-甲基丁基)-2-氧代-四氫化咪唑,4-甲基-5-(δ-羧基-γ,γ-二甲基丁基)-2-氧代-四氫化咪唑,4-甲基-5-(ω-羧基-正壬基)-2-氧代-四氫化咪唑及4-甲基-5-(ω-羧基-正十七基)-2-氧代-四氫化咪唑。前三者已作過初步的微生物效應試驗,對於lactobacillus casei及saccharomyces cerevisiae都有顯著的反生素效應。第四個化合物因為在水中溶度太低,故尚未能作它的微生物效應試驗。

The effect of successive or simultaneous action of the vagus stimulation and the humoral agent (secretion) upon the secretion of the pancreatic juice was studied in dogs with chronic pancreatic fistula and in acute conditions. In both groups of animals the right vagus nerve had been sectioned for 5—6 days, and observations were made under nembutal anesthesia. The results were essentially the same in both groups of dogs. They are as follows: (1) When the peripheral end of the sectioned vagus was stimulated with...

The effect of successive or simultaneous action of the vagus stimulation and the humoral agent (secretion) upon the secretion of the pancreatic juice was studied in dogs with chronic pancreatic fistula and in acute conditions. In both groups of animals the right vagus nerve had been sectioned for 5—6 days, and observations were made under nembutal anesthesia. The results were essentially the same in both groups of dogs. They are as follows: (1) When the peripheral end of the sectioned vagus was stimulated with the faradic current immediately following the cessation of response to the humoral agent (pure secretin injected i. v. in various doses, or dilute HCl introduced into the small intestine), the latent period of the pancreatic secretion became shorter and the amount of secretion was much increased as compared with the mere application of nervous stimulation without giving a previous dose of the humoral agent. (2) When the vagus was stimulated simultaneously with the application of the humoral agent, the amount of the pancreatic juice secreted was about 2 times of the additive sum obtained by separate action of the nervous stimulation and humoral agent. (3) Immediately following the cessation of the effect of the humoral agent, injection of pilo-. carpine gave rise to a secretory response shorter in latency and greater in amount. It appears from the above results that the nervous and humoral mechanisms reenforce each other in stimulating the secretion of the pancreatic juice.

本实验系用狗为对象,分慢性和急性实验两种,但实验均在戊皖巴比妥钠的麻醉下进行。我们观察了神经与激素二因素,于不同的结合方式的情况下,对胰液分泌调节中的相互关系,结果证明: (一)在激素刺激(注胰液素入静脉或注盐酸入小肠)对胰腺的效应停止后的10分钾内,紧接着刺激切断4—6天后的颈部迷走神经离中端,所引起的胰液分泌,较单独刺激同一神经时所引起的胰液分泌量多,潜伏期短, (二)神经与激素二因素同时作用,所引起的胰液分泌量,大大超过此二因素分别作用所得的效应的总和。 (三)在激素对胰腺的刺激效应停止后的10分钟内,紧接着注射毛果芸香硷,所引起的胰液分泌量,较单独注射毛果芸香碱为多。根据以上结果可以认为:神经与激素二因素在胰液分泌调节中有相互加强的作用。

~~

在两只狗身上确定了三种化学刺激物:大白菜汁、5%蛋白胨和5%乙醇直接注入大胃时引起小胃的分泌活动。结果表明,5%乙醇的泌作用最强,5%蛋白胨次之,而大白菜汁只有微弱的泌作用。用食物性和御性反射进行“冲突”后,胃液分泌量显著升高,酸度和消化力亦有变化。条件反射系统建立过程中,胃液分泌量亦升高,由此可见,化学时相的胃液分泌对大脑皮层的机能状态有相当大的依从关系。

 
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