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细胞移行
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  cell migration
     Methods IEC 6 cells were inoculated in 6 well microplates and injured in 72 h, and added with Hi, B1, B4, B9, B13. Then D PBS to negative control in the same amount and EGF to positived control, the cell migration was observed in 24, 48 and 72 h after treatment.
     方法  IEC- 6接种于 6孔培养板 ,72 h后损伤细胞 ,并加入不同剂量的 Hi、B1、B4、B9和 B13溶液 10 0 μL,空白组加等量 D- PBS,阳性对照组加表皮生长因子 (EGF) ,加药后 2 4 ,4 8和 72 h观察细胞移行
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     Combined administration of B13 and Hi stimulated cell migration in a synergistic manner (P<0 05-0 01 vs the control).
     B13和 Hi配伍应用后 ,对 IEC- 6细胞移行具有协同促进作用 ,与对照组、Hi和 B13组比较 2 4 ,4 8和 72 h均具有明显差异 (P<0 .0 5~ 0 .0 1)。
短句来源
     Compatible application of B13 and Hi shows the synergism on IEC 6 cell migration.
     B13和 Hi配伍应用对细胞移行具有协同促进作用
短句来源
     Conclusion: AI could promote IEC 6 cell differentiation by means of inducing the ODC activity and biosynthesis of polyamine, but without significant effect on cell migration.
     结论 :AI通过诱导IEC 6细胞ODC活性和多胺的生物合成促进细胞分化 ,而对细胞移行无明显作用
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     Methods The cultured human RPE cells added with suramin(1 5,15, 150 mg/L)were measured in a in vitro wound healing model. The cell migration ra te was observed at hours 12,24 and 48 respectively.
     方法 在体外培养的RPE细胞的损伤模型中 ,加入不同浓度的舒拉明 (1 5 ,15 ,15 0mg/L) ,观察 12h、2 4h和 48h 3个时间点RPE细胞移行率。
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  cellular translocation
     After hRPE cells were exposed to direct current electric fields with the tension of 0,4, 6 and 8 V/cm, serial images were taken at 15 minuets intervals within 2 hours by photomicroscope to observe the migration of the cells, and then the migrating distances and angle between the cellular translocation direction and the field vector were measured.
     将细胞分别暴露于强度为0、4、6、8V/cm的电场中,显微摄像系统连续记录2h中每隔15min细胞移行的变化图像,测量细胞移行距离及细胞移行方向与场线间夹角。
短句来源
     Se rial images of the cells were taken at 15min intervals within 2h, and the displa cement of the cells and the angle between the cellular translocation direction a nd the field vector were measured.
     观察并记录2h中每隔15min细胞移行的变化图像,测量细胞移行距离、细胞移行方向及其与场线间夹角。
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  “细胞移行”译为未确定词的双语例句
     After adding 1μg/ml of thrombin and 10μg/ml of TP508. the spot density was 104. 4 ±12. 2 and 109.4±14. 6, respectively.
     培养液组细胞移行斑点密度为 76.6±13.8,添加 1μg/ml凝血酶和 10 μg/ml TP508,其斑点密度分别增至 104.4±12.2和109.4±14.6。
短句来源
     HGF showed effects on migration of 9 3 %, 113 0 %, 91 7 % and 50 3 % at the concentrations of 2,10,50, 100 μg/L, respectively.
     HGF可明显促进 RPE细胞移行 ,促移行能力分别为 113.0 % (10μg/ L ) ,91.7% (5 0μg/ L )和 5 0 .3% (10 0μg/ L )。
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     The results showed that about 97.6% of transplanted dentate granule cells migrated into the area of dentate gyrus and CA3 sector while only 2.4% cells migrated into the CA2 and CA1 sectors.
     结果显示,97.6%的细胞移行到齿状回和CA3区,仅有2.4%细胞移行到CA2和CA1区。
短句来源
     Effect of ginsenoside Rh_2 on cultured PC-3M cells in vitro
     人参单体皂甙Rh_2对前列腺癌细胞株PC-3M细胞移行周期的影响
短句来源
     In wound healing study, migrated cell count was significantly lower in MDA-MB-435/FRNK cells (0.35±0.02) than that in wild type cells (0.58±0.06, P<0.05).
     在划痕修复实验中,稳定高表达FRNK蛋白的MDA-MB-435细胞移行面积与空白面积之比为0.35±0.02,与野生型MDA-MB-435细胞(0.58±0.06)相比划痕修复能力明显减弱(P<0.05);
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  cell migration
Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor -induced cell migration
      
The aim of this study was to investigate the role of p38 mitogen-activated protein kinase (MAPK) in cell migration induced by platelet-derived growth factor (PDGF).
      
A Transwell cell migration system was used to determine the effects of PDGF treatment on the migration of NIH3T3 cells and the influence of p38 deficiency on this process in a p38 gene knockout (p38-/-) mouse embryonic fibroblast cell line.
      
Furthermore, the PDGF-induced cell migration was significantly blocked in p38 gene knockout (p38-/-) mouse embryonic fibroblasts (MEFs) (P >amp;lt; 0.001) as compared with the wild type cells (p38+/+).
      
p38 MAPK plays an important role in the regulation of cell migration induced by PDGF.
      
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  cellular translocation
Anti-integrin antibodies inhibited the production of protrusions as well as cellular translocation.
      
Hence we exclude the cellular translocation of the investigated CPP to follow the barrel-stave model.
      
The integrins provide traction for cellular translocation, whereas the netrins appear to contribute to the direction of the migrations.
      


Eight cases (7 male, 1 female) of proliferative myositis are reported. The average age is 41 years. The duration of the disease is 5 days in 1, 3-6 months in 4, 2 years in 2, and not recorded in 1 case. In 5 cases the lesions are located in the extremities; one case each on the chest wall, occipital region and left mandibular angle respectively. Only case 2 has a history of trauma. The lesions are single or multiple. The margins of the lesions usually are ill-defined. These lesions are rather hard. The average...

Eight cases (7 male, 1 female) of proliferative myositis are reported. The average age is 41 years. The duration of the disease is 5 days in 1, 3-6 months in 4, 2 years in 2, and not recorded in 1 case. In 5 cases the lesions are located in the extremities; one case each on the chest wall, occipital region and left mandibular angle respectively. Only case 2 has a history of trauma. The lesions are single or multiple. The margins of the lesions usually are ill-defined. These lesions are rather hard. The average diameter of the lesions is about 5 cm. In one case the lesion is merged closely with skeletal muscles, the muscles being replaced by polygonal or irregular large cells with abundant basophilic or amphophilic cytoplasm. No longitudinal or transverse striations are seen. The nuclei are large with a single red nucleolus. Such large cells seem to be fibrocytes. No calcification, chondroid or osteoid changes are seen in the lesions.

本文收集本所病理室外检2例及会诊6例,共8例增生性肌炎。四肢多见。病变为瘢痕组织或横纹肌间见大细胞增生。后者胞浆丰富,嗜碱性或嗜双色,核圆、边界不清有明显红核仁,并见大细胞向纤维细胞移行

Obervations on the endothelial differentiation and tumor ang-iogenesis were established by transplantating the S. 180 to the albino mice ear. A growing small tumof nodule with newly growth blood capillaries crawlingly penetrating into the nodule was noticed after 72-96 hours. Microscopically, these capillary endothelial cells come not only from endotnelium of blood vessels but also from perichondrial connective tissues. Futhermore, cartilage cells and atrophic striated muscles transfer to endothelial cells is...

Obervations on the endothelial differentiation and tumor ang-iogenesis were established by transplantating the S. 180 to the albino mice ear. A growing small tumof nodule with newly growth blood capillaries crawlingly penetrating into the nodule was noticed after 72-96 hours. Microscopically, these capillary endothelial cells come not only from endotnelium of blood vessels but also from perichondrial connective tissues. Futhermore, cartilage cells and atrophic striated muscles transfer to endothelial cells is also present. As compared with literature, this method has more advantages than that of transplantation with rabbit cornea and chicken embryo chorioallantoic membrane.

鼠耳移植S.180,72—96小时后出现小结节,并见小血管呈匍匐状穿入结节。切片所见新生血管除来自宿主血管内皮细胞外,尚可来自软骨膜结缔组织,并见软骨细胞及萎缩横纹肌向内皮细胞移行。该模型便于对血管观察,较角膜及鸡胚尿囊膜移植为佳。

One hundred cases of esophagectomy specimens were reexamined by light micros-copy,electron microscopic study was also carried out in 2 patients.Multinucleatedgiant cells were found in 34 cases an obviously higher incidence than in the ade-nocarcinomas of the gastrointestinal tract.More multinucleated giant cells werefound in highly differentiated carcinomas.Nevertheless,there was no obvious rela-tion between the occurrence of multinucleated giant cell and the degree of reactivehyperplasia of the stroma.Two morphologic...

One hundred cases of esophagectomy specimens were reexamined by light micros-copy,electron microscopic study was also carried out in 2 patients.Multinucleatedgiant cells were found in 34 cases an obviously higher incidence than in the ade-nocarcinomas of the gastrointestinal tract.More multinucleated giant cells werefound in highly differentiated carcinomas.Nevertheless,there was no obvious rela-tion between the occurrence of multinucleated giant cell and the degree of reactivehyperplasia of the stroma.Two morphologic types could be defined namely,(1) newlyformed type,and(2)mature type.Most multinucleated giant cells occurred,singly or in groups,in the stroma adjacent to carcinoma cell nests,they could in-filtrate into the carcinoma tissue also.They extended pseudopods,enclosed andengulfed tumor cells.The phagocytized carcinoma cells appeared degenaration andnecrosis.Ultrastructural features of the multinucleated giant cells were the abun-dance of lysosome like,electron dense bodies scattered throughout the cytoplasm.Phagocytized cell debris and electron dense stripes could be found in the cytoplasm.Mononuclear marcrophages were intimately associated with multinucleated giantcells.Most mononucleated macrophages were epitheloid.The transitional processesfrom mononucleated marcrophages to multinucleated giant cells could be seen clearly.The multinucleated giant cells could be fused with each other,and the mono-nucleated marcrophages could be joined continuously.

在光镜下复查了手术切除之食管癌标本100例,对其中2例曾进行超微结构观察。发现多核巨细胞者34例,分化程度较高者,多核巨细胞的出现率也较高,但与间质反应性增生的程度无明显关系。本文详细描述了多核巨细胞的形态与分布。多核巨细胞伸出的伪足包围并吞噬癌细胞。本文材料表明,多核巨细胞显然来源于单核巨噬细胞的互相融合,并清楚地观察到了单核巨噬细胞融合成多核巨细胞的移行过渡过程。本文对单核巨噬细胞与多核巨细胞的功能及生物学意义作了简要讨论。

 
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