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      第一内含子
相关语句
  first intron
     It includes the complete first exon(1~61?bp),first intron(62~703?bp) and partial sequence of exon 2(704~732?bp) in the 732 base pairs of FSHβ gene sequence,and the content of A+T(66.12%) is higher than G+C(33.88%).
     在测定出的FSHβ亚基基因732 bp序列中,包括第一外显子全序列(1~61 bp),第一内含子全序列(62~703 bp)以及第二外显子部分序列(704~732 bp),并且序列中A+T含量(66.12%)高于G+C(33.88%)。
短句来源
     Expression of Adenovirus-mediated pGH cDNA with First Intron in CHO Cells
     腺病毒介导的含第一内含子pGH cDNA在CHO细胞中的表达
短句来源
     Results The luciferase reporter gene construct containing the first intron of α 1(I) collagen gene (-804~+1 452, was called as PGL3 col) had a higher level of gene expression, as compared with the construct lacking the first intron 〔was called as PGL3 col (△intron)〕 in activated HSCs (315±45 U/mg protein vs 220±70 U/mg protein, P <0.05).
     结果 构建的含α1(I)基因第一内含子片段的荧光素酶报告基因 (PGL3 col)比不含α1(I)基因第一内含子的报告基因〔PGL3 col( △intron)〕在HSC中有较强的表达 (荧光素酶活性为 3 15± 45U/mg蛋白与 2 2 0± 70U /mg蛋白 ,P <0 .0 5 )。
短句来源
     Construction of Expression Vector of pGH cDNA with First Intron and its Expression in COS7 Cells
     含第一内含子猪生长激素cDNA基因在COS7细胞中的表达
短句来源
     An Analysis of Bioinformation Human Her-2 Gene Proximal Promoter and the First Intron
     Her-2基因启动子及第一内含子的生物信息学分析
短句来源
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  the first intron
     Results The luciferase reporter gene construct containing the first intron of α 1(I) collagen gene (-804~+1 452, was called as PGL3 col) had a higher level of gene expression, as compared with the construct lacking the first intron 〔was called as PGL3 col (△intron)〕 in activated HSCs (315±45 U/mg protein vs 220±70 U/mg protein, P <0.05).
     结果 构建的含α1(I)基因第一内含子片段的荧光素酶报告基因 (PGL3 col)比不含α1(I)基因第一内含子的报告基因〔PGL3 col( △intron)〕在HSC中有较强的表达 (荧光素酶活性为 3 15± 45U/mg蛋白与 2 2 0± 70U /mg蛋白 ,P <0 .0 5 )。
短句来源
     An Analysis of Bioinformation Human Her-2 Gene Proximal Promoter and the First Intron
     Her-2基因启动子及第一内含子的生物信息学分析
短句来源
     Especially the first intron is unusually long, 7164bp in length, the others were very short between 78bp and 253bp.
     第一内含子超大,长7164bp,其它内含子序列均较短,大小在78bp到253bp之间。
短句来源
     Study on the First Intron Regulating Transcription of Human α1(Ⅰ) Collagen Gene
     人Ⅰ型胶原基因第一内含子调节转录的研究
短句来源
     In order to study intron effect, whey acid protein(WAP) gene the first intron was cloned to human G-CSF gene 5′end, and this fragment was directed by WAP 2.6kb promoter.
     内含子在转基因动物的基因表达中具有重要作用,以乳清酸蛋白(WAP)基因5′区为调控序列,人基因组G-CSF基因为目的片段,将WAP基因第一内含子插入G-CSF基因5′端,构建成转基因动物乳腺表达载体。
短句来源
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  intron 1
     Acquirement and Identification of a Novel Intron 1 of Human Na(+) K(+) Exchanging ATPase α1 Subunit Gene
     未知人Na(+)-K(+)-Exchanging ATPase α1亚基基因第一内含子的获得及鉴定
短句来源
     Relationship Between the First Base of Splice Donor of Wx Gene Intron 1 and Amylose Content in Yunnan Indigenous Rice Varieties
     云南地方稻种Wx基因第一内含子供体+1位碱基变异与直链淀粉含量的关系
短句来源
     One SNP(-157G/A) was found in intron 1, One SNP(+115C/G) was found in Eexon 2, One SNP(+877G/C) was found in intron 3. 2 The SNP3 was conformed to expectation of the Hardy-Wei nberg rule.
     结论:1 在安徽汉人中,Resistin基因存在单核苷酸多态性,分别为第一内含子—157位G/A、第二外显子+115位的C/G、第三内含子+877位的G/C。
短句来源
     G/T polymorphisms were located in intron 1 of M gene of MN blood group system.
     目的MN血型M基因的第一内含子中有一个G/T颠换位点,检测该单核苷酸多态性在中国汉族人群中分布状态。
短句来源
     Bioinformatic analysis indicated that putative promoter sequence of the cloned Xinong Saanen Dairy Goat β-casein 5' flanking sequence shared 96%~98% homology with other goat β-casein gene promoters. Xinong Saanen Dairy Goat β-casein 5' flanking sequence region contained promoter sequences and putative recognition sites for several transcriptional factors, including HOXF, Oct1, AP1, CEBP, STAT, NFKB, GR, ER, PR, ETS and the intron 1, exon 1 and exon 2 of the goat β-casein gene.
     生物信息学分析显示:该序列与已公布的其它山羊β-酪蛋白基因序列具有极高同源性(96%~98%),包含有TATA启动子序列和HOXF、Oct-1、AP1、CEBP、STAT、NFKB、GR、ER、PR、ETS 等转录因子识别位点,该序列保留了β-酪蛋白第一内含子、第一外显子和第二外显子及其信号肽部分。
短句来源
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  “第一内含子”译为未确定词的双语例句
     Results ⑴Both ACI and control groups M1++ and M1+- were major frequent genotypes in Beijng area,M2++ were major frequent genotypes in intron-1;
     结果 北京地区403例受检者中载脂蛋白AI基因启动子均以M1++和M1+-为主要基因型,第一内含子大多数为M2++基因型;
短句来源
     4. Specific primers P4, P5 and P6 were designed to amplify fragments from chicken A-FABP gene.
     4、根据鸡A-FABP基因第一外显子及第一内含子序列设计特异性扩增引物p4-P.,应用PCR-SSCP分析在A-FABP基因上发现P。 、P。
短句来源
     Artiga et al found there were two hot spot between the 5’ noncoding intron and first exon, ie 106-127bp and 423-443bp. The latter mutation was related with the increase expression of BCL-6. It indicated this region contains a regulatory element.
     Artiga MJ等发现突变区位于5’第一非编码外显子和第一内含子3.5kb的范围内,具两个突变热点,106-127bp和423-443bp,后者热点的突变与BCL-6水平的升高相关,表明这一区域可能包含一个调控元件,它的突变可改变与假定的BCL-6调控转录因子的结合。
短句来源
     Results:The overall allele frequencies(TNFB1 32.3%, TNFB2 67.7%,TNF1 88.9%, TNF2 11.1%) and genotype distribution(TNFBl homozygote 11. 1%, TNFB1/TNFB2 42. 2%, TNFB2 homozygotes46. 7%, TNF1 homozygotes 77.8%, TNF1/TNF2 22. 2%)in 45 patients with MODS were compared with those values in normal individuals.
     并采用ELISA方法检测MODS患者血浆的TNFα和TNFβ浓度。 结果:在45例MODS患者中,TNFα启动子-308位点和TNFβ第一内含子+250位点等位基因频率是TNF1 88.9%,TNF2 11.1%,TNFB1 32.3%,TNFB2 67.7%;
短句来源
     In 2001, Wilson and his colleagues cloned another two members - human WNK1 gene and WNK4 gene which were located on chromosome 12 and 17, respectively.
     2001年,Wilson等克隆了此家族的另两个成员——人的WNK1和WNK4基因,分别位于12号和17号染色体,这两个基因是一种孟德尔遗传型高血压病的致病基因,致病突变分别是WNK1基因第一内含子的大片段缺失,导致患者白细胞的基因表达量提高5倍左右。
短句来源
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  first intron
Ribosomal Protein Binding with the First Intron of the Human rpS26 Pre-mRNA Stimulates Its Interaction with Proteins Extracted f
例句来源      
As shown by nitrocellulose filtration assays with RNA fragments transcribed from various regions of the human ribosomal protein (rp) S26 gene, proteins of the 40S ribosome subunit bind to the first intron of the rpS26 pre-mRNA.
例句来源      
Small-subunit proteins did not affect the efficiency of in vitro splicing of a pre-mRNA fragment corresponding to the first intron, second exon, second intron, and a part of the third exon of the rpS26 gene.
例句来源      
The binding was specific, since human rpS19 had an order of magnitude lower Ka with the first intron and did not bind with the rpS26 mRNA.
例句来源      
Immunoassays with specific antibodies showed that rpS26 contained in the nuclear extract of HeLa cells binds to the first intron of its pre-mRNA and, less efficiently, to its mRNA.
例句来源      
更多          
  the first intron
Ribosomal Protein Binding with the First Intron of the Human rpS26 Pre-mRNA Stimulates Its Interaction with Proteins Extracted f
例句来源      
As shown by nitrocellulose filtration assays with RNA fragments transcribed from various regions of the human ribosomal protein (rp) S26 gene, proteins of the 40S ribosome subunit bind to the first intron of the rpS26 pre-mRNA.
例句来源      
Small-subunit proteins did not affect the efficiency of in vitro splicing of a pre-mRNA fragment corresponding to the first intron, second exon, second intron, and a part of the third exon of the rpS26 gene.
例句来源      
The binding was specific, since human rpS19 had an order of magnitude lower Ka with the first intron and did not bind with the rpS26 mRNA.
例句来源      
Immunoassays with specific antibodies showed that rpS26 contained in the nuclear extract of HeLa cells binds to the first intron of its pre-mRNA and, less efficiently, to its mRNA.
例句来源      
更多          
  intron 1
Male-specific DNA-protein complexes were revealed with labeled oligonucleotides corresponding to fragments +1150/+1449, +1358/+1449, +1397/+1449, and +1417/+1449 of intron 1 of the Ste1 gene.
例句来源      
Intron 1 of Ste1 gene contains the repeated element of ID family inserted after duplication of the ancestor gene.
例句来源      
This mRNA, which contained 225 bp of the intron 1 proximal region, was detected in HeLa cells by reverse transcription-polymerase chain reaction.
例句来源      
Alternative transcripts containing intron 1 were also found in mouse and rat cells.
例句来源      
RET exons 8, 10, 11, 13, 14, 15, and 16 and intron 1 along with the GFRA1 5'-UTR were screened by PCR and subsequent direct sequencing or RFLP analysis.
例句来源      
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