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|  | | 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。 | |
Western blotting showed that the protein had a high specificity against mouse-anti-Sj14-3-3 monoclonal antibody and rSj14-3-3 had a promising immune reactivity.
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Production and immunochemical characterization of monoclonal antibodies toCorynebacterium sepedonicum, the causative agent of po
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Five stable hybridoma lines producing monoclonal antibodies toCorynebacterium sepedonicum were obtained.
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The specificity of monoclonal antibodies obtained was characterized.
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Comparative immunochemical characterization of polyclonal and monoclonal antibodies to aflatoxin B1
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ER, PgR and monoclone M4G3 assays were performed for positive lymph nodes to confirm the primary foci to be breast cancer.
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Results: Some Vβ subfamily PCR products from 4 patients contained monopeak (monoclone) or a dominant peak (oligoclone).
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After CNBr treatment, the antigenic epitope(s) for a flavivirus-common monoclone (NARMA 24) and those for NARMA 16 appeared to locate on different fragments, while the epitopes for other monoclones lost their antigenicities.
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According to a multi-step hypothesis, the antigenic stimulation in a susceptible host is the first hit, giving rise to a benign monoclone.
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A monoclonE al antibody against this factor has been obtained.
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| | Thirty seven cases of multiple myeloma were analyzed, among which 18 weremonoclonal immune globulin type, 12 were monoclonal immune globulin withBence-Jones protein type, 2 light chain type and others were polyclonal immuneglobulin, nonproducing, nonsecretary, plasma-cell leukemia, undetermined type,respectively. Ninteen light chain cases were examined, 13 cases in κ, and 6 in λ.In some cases the immune globulin in plasma cell of bone marrow were examinedtoo. The population doubleing time of myloma cell, ha... | | 多发性骨髓瘤免疫学检查,对本病早期诊断、疗效观察及预后估计有重要意义。本文报告了37例多发性骨髓瘤免疫学分型的根据和特征,根据瘤细胞能否产生和分泌M成分,将本病分为有M成分型和无M成分型。有M成分型中依M成分的不同可分为单克隆免疫球蛋白型、单克隆免疫球蛋白并BJP型、轻链型和多克隆M成分型;无M成分型根据瘤细胞内有无M成分可分为不产生型和不分泌型。 | | 文摘来源 | | Cell hybridization was done by means of polyethylene glycol (PEG)in suspension.Seven kinds of heterokaryons showing pr- emature condensed chromosomes were obtained.A hybridoma cell line had been established which produced monoclonal anti- body anti human complement 4.On the basis of showing prem- ature condensed chromosomes of heterophasic heterokaryons between CHO metaphase cells and bone marrow lymphocytes from patients with leukemia,their potential proliferation index of bone marrow cell population was s... | | 本文报告了1980年以来我们在细胞杂交技术及其应用研究中取得的各项阶段性成果。在细胞杂交技术方面,用分子量在1000、2000、4000、6000的PEG为融合介质,获得了中国仓鼠成纤维细胞Wg3-h、人HeLa细胞、人胃腺癌细胞SGC-T901的同种异核体,以及雄性麂肺细胞KIZ-7901-中国仓鼠成纤维细胞Wg3-h、中国仓鼠卵巢细胞CHO-人外周血港巴细胞、中国仓鼠卵巢细胞CHO-正常人骨髓细胞、中国仓鼠卵巢细胞CHO-白血病患者骨髓细胞的异种异核体,并成功地显示了上述各种细胞组合的PCC图象。获得了在体外长期传代培养的小鼠骨髓瘤细胞NS-1-Ag8-BALB/c小鼠脾脏淋巴细胞以及小鼠骨髓瘤细胞SP2/0-Ag14-免疫后的BALB/c小鼠脾脏淋巴细胞的种内杂种细胞系。在细胞杂交技术的应用方面,重点在诱导“熟前凝聚染色体”(PCC),分析白血病患者骨髓细胞的群体增殖潜能。并据以判断白血病患者病情进展、疗效和预后,以及制备分泌抗人C4单克隆抗体的杂交瘤细胞系。本文对PEG的融合性能、白血病患者PPI值升高的机制、杂交瘤细胞的亚克隆化等问题进行了初步探讨。 | | 文摘来源 | | Monoclonal antibody marker studies performed on 10 cases of NHL showed that all tumor cells were positive for Leu 1. Leu3. Leu4 and negative for Leu2, OKT6, B1, K, A. The percentage of E-rosettes among medium and large cells range from 45 to 67%. 5 cases showed not possitivity for ANAE. Studied urider the light microscope 6 types or, cells could be identified: 1, Cells with twisted "swingly" nuclei and abundant pale cytoplasm. 2. Cells with round pale staining nuclei and abundant clear cytoplasm. 3. "large ... | | 本文分析10例经单克隆抗体标记证实为外周T细胞淋巴瘤的病理形态,每例均用ABC法作Leu_1、Leu_2、Leu_3、Leu_4、OKT_3、oKT_6,HLA-DR(Ⅰ_s)、B_1、Kappa(k)、Lainbda(λ)免疫标记测定,证实为辅助T细胞来源,E花结测定见大中淋巴样细胞中有45~65%形成花结,5例ANAE点状阳性,2例ACP阳性。光镜下Peri TL的细胞形态可归结为六类。作者根据其相互之间的过渡形态推测了外周T淋巴细胞的转化过程,并结合肿瘤细胞的生长方式建议Peri TL再增加以下四个亚型:(1)透明圆核细胞性,(2)多形细胞性,即透明扭核细胞性,(3)混合T细胞性,(4)单纯圆细胞性。 | | 文摘来源 | |   | | << 更多相关文摘 |
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