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      单克隆
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  monoclonal
    Regulation of apoptosis in hepatoma cells by bcl-2 and bax and primary study of hepatoma apoptosis-related monoclonal antibody
    bcl-2和bax对肝癌细胞凋亡的调控及肝癌凋亡相关单克隆抗体初步研究
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    The Clinical & Experimental Research on the K-ras Gene Point Mutations and Monoclonal Antibodies of the Gene Expression Products P21 Protein in Pancreatic Adenocarcinoma
    胰腺癌K-ras基因点突变的临床应用研究及其表达产物P21蛋白的单克隆抗体实验研究
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    Effects of Anti-CD44 Adhesion Molecule Monoclonal Antibody on and Its Mechanisms in the Proliferation and Differentiation of Human HL-60 Cells
    抗CD44粘附分子单克隆抗体对HL-60白血病细胞增殖及分化的影响及其机制探讨
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    The Cytotoxicity Study of Monoclonal Antibodies Specific for TRAIL Receptors on Human Renal Cell Carcinoma, in Vitro and in Vivo
    TRAIL受体单克隆抗体诱导人肾癌细胞凋亡的实验研究
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    Preparation of the Specific Keratin Monoclonal Antibody of Anti-Lingual Squamous Cell Carcinoma
    抗舌癌特异性角蛋白单克隆抗体的制备
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  monoclone
    Epratuzumab as anti-CD22 monoclone antibody in treatment of non-Hodgkin's lymphoma
    抗CD22单克隆抗体Epratuzumab治疗非霍奇金淋巴瘤
短句来源
    PREPARATION OF HUMAN MONOCLONE ANTIBODY AGAINST OVARIAN CANCER
    抗卵巢癌人单克隆抗体的研制
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    Purpose:To produce a new monoclone antibody against HER-2/Neu oncoprotein (p185), and to explore the relationship between HER-2/Neu abnormal expression and prognosis of axillary lymphnode-negtive breast cancer (ANNBC).
    研制抗HER-2/Neu癌蛋白(p185)的单克隆抗体,并研究该基因过量表达与腋窝淋巴结阴性乳腺癌(ANNBC)预后的关系,以研制国产HER-2/Neu表达诊断试剂。
短句来源
    The change of OKT3 + , OKT4+ and OKT8 + subsets in human peripheral blood T lymphocytes damaged by 2.5 Gy e gamma rays was studied by indirect immunofluorescent method in the presence and absence of IL-2. The specific combination ability of OKT3, OKT4 and OKT8 monoclone antibodies with membrane antigen of the lymphocyte subsets was determined.
    报道了用2.5Gy的~(60)Coγ射线照射外周血淋巴细胞,在照射后用间接免疫荧光法,检测单克隆抗体OKT_3~+、OKT_4~+和OKT_8~+与淋巴细胞膜抗原特异性结合的能力,以评价外周血T淋巴细胞亚群总T细胞(OKT_3)、辅助T细胞(OKT_4)和抑制T细胞(OKT_8)的变化。
短句来源
    We investigated the expression ofras onocogene product p21 and EGFr in normal bladder tissues and bladder cancer tissues with p21 and EGFr monoclone antigen by immunohistochemical method.
    应用p21和表皮生长因子受体(EGFr)单克隆抗体,通过免疫组织化学方法检测正常膀胱组织和膀胱癌组织中ras癌基因产物p21和EGFr的表达状况。
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  “单克隆”译为未确定词的双语例句
    Induction of Apoptosis in Glioma Lines by Anti-DR4 McAb and Anti-DR5 McAb
    抗DR4、DR5单克隆抗体诱导胶质瘤细胞株凋亡的研究
短句来源
    Study on Radiommunoimaging and Radiommunotherapy with ~(131)Ⅰ-Anti-CEA, TPS Monclonal Antibody in Nude Mice Bearing Human Breast Carcinoma
    ~(131)Ⅰ标记的抗CEA、TPS单克隆抗体在荷人乳腺癌裸鼠体内的放射免疫显像及治疗的研究
短句来源
    Humanization of Mab SM5-1 and the Anti-tumor Effects in Vitro and Vivo
    SM5-1单克隆抗体的人源化及其体内外抗肿瘤作用研究
短句来源
    ESTABLISHMENT OF FOUR HYBRIDOMA CELL LINES SECRETING ANTI-HUMAN IGA MCABS
    分泌抗人IgA单克隆抗体(McAb)杂交瘤细胞株的建立
短句来源
    EFFECT OF ~(60)CO γ-RAYS ON THE LYMPHOCYTE SUBSETS WITH MONONOCLONAL ANTIBODIES
    用单克隆抗体研究~(60)Coγ线对淋巴细胞亚群的辐射效应
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  monoclonal
Western blotting showed that the protein had a high specificity against mouse-anti-Sj14-3-3 monoclonal antibody and rSj14-3-3 had a promising immune reactivity.
例句来源      
Production and immunochemical characterization of monoclonal antibodies toCorynebacterium sepedonicum, the causative agent of po
例句来源      
Five stable hybridoma lines producing monoclonal antibodies toCorynebacterium sepedonicum were obtained.
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The specificity of monoclonal antibodies obtained was characterized.
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Comparative immunochemical characterization of polyclonal and monoclonal antibodies to aflatoxin B1
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  monoclone
ER, PgR and monoclone M4G3 assays were performed for positive lymph nodes to confirm the primary foci to be breast cancer.
例句来源      
Results: Some Vβ subfamily PCR products from 4 patients contained monopeak (monoclone) or a dominant peak (oligoclone).
例句来源      
After CNBr treatment, the antigenic epitope(s) for a flavivirus-common monoclone (NARMA 24) and those for NARMA 16 appeared to locate on different fragments, while the epitopes for other monoclones lost their antigenicities.
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According to a multi-step hypothesis, the antigenic stimulation in a susceptible host is the first hit, giving rise to a benign monoclone.
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A monoclonE al antibody against this factor has been obtained.
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         Subpopulations of infiltrating mononuolear cells in 51 resected pulmonary carcinoma specimens were observed, using immunohistochemioal technique with monoclonal antibodies of OKT3, OKT4, OKT8, OKM1, B1 and Leu7. The majorconstituent of the infiltrating mononuolears was the T cell. Maorophages came next. B cells were less and K/NK cells the fewest. OKT3+ cells (T pan), OET4+ cells (T helper/inducer), OKT8+cells (T suppressor/cytotoxic) and OKM1+ cells (macrophages) infiltrated at the periphery of the tumor, ...
            用单克隆抗体、卵白素生物素复合物法(ABC法),观察51例原发性肺癌组织中各种单核性细胞亚型的分布特点和胶原纤维反应情况。发现浸润的单核性细胞中T淋巴细胞最多,其次为单核巨噬细胞,两者除大量存在于肿瘤边缘部外,还见于肿瘤间质,乃至肿瘤实质中,与癌细胞直接接触。B淋巴细胞多集中成滤泡状,散在分布于肿瘤边缘及附近正常肺组织中。杀伤细胞/自然杀伤细胞(K/NK细胞)的数量极少。肿瘤周围胶原纤维反应程度与单核性细胞浸润程度相平行。作者认为二者都是机体肿瘤免疫的局部表现。
文摘来源
         A hybridoma from mouse myeloma cell line SP2/0(HGPRT-) and human peripheral lymphocytes.was obtained in the presence of PEG and selected in hypoxanthine-aminopterine-thymidine (HAT) medium.It was proved that 5-12 human chromosomes were retained in the hybrid population,with no interspecific chromosome translocation observed.Monocloned A4 population retained human chromosomes 9、11、X、14、18、19 and 22.The electrophoretic zymogram of G6PD in hybridoma shows a three-banded pattern, suggesting both parents specifi...
            小鼠骨髓瘤细胞SP2/0(HGPRT-)与人外周血淋巴细胞经PEG介导融合,HAT培养基选择,获得了体外永久培养的人鼠杂交瘤NJ84。细胞遗传学分析证实杂种群体中尚保留5~12个人染色体,未查见种间染色体易位。A_4单克隆中保留着人9、11、X、14、18、19、22号染色体。杂种细胞G_6PD同工酶电泳出现三带型酶谱,证实人和鼠的G_6PD在杂种细胞中均有表达。同时观察比较了杂种及其亲本对细胞松弛素B的反应。这种人鼠杂交细胞可望用于人类基因定位、制备人类免疫球蛋白链基因克隆和人类单克隆抗体,也可用于恶性表达分析等方面的研究。
文摘来源
         Human acute granulocytic leukemia leucocytes and mouse myeloma Ag14—SP2/0(HGPRT~-) were used as parental cells for the fusion experiments in the presence of PEG. The cells were grown on the feed layer cells after being fused. Three hybrid clonse were selected and isolated in the HAT medium: XM—H—B_1, XM—H—A_2, and XM—H—D_2. Giemse—11 differential staining, G—banding, C—banding techniques and isozymes analysis of G6P—D on cellulose acetate membrane electrophoresis were used to identify the above clones. our ...
            我们用急性粒细胞性白血病病人外周血白细胞和小鼠骨髓瘤Ag14—SP2/0细胞(HGPRT~-)为材料,以国产聚乙二醇(分子量10,000)为促融剂,杂交后在含有滋养层细胞的24孔培养板中经HAT培养液选择后获得三个杂交瘤细胞系:XM—H—B_1,XM—H—A_2和XM—H—D_2,经Giemsa—11分化染色,染色体G分带、C分带和G6P—D同功酶的醋酸纤维素薄膜电泳鉴定,证实为人鼠杂交瘤。值得提出的是杂种细胞的上清,经中国医学院科学院基础所测定:①对抗人全血出现沉淀线;②作SDS电泳——PAGE出现克隆带,分子量65,000万左右;③作各种人免疫球蛋白(包括IgG亚类)均阴性,但对一种抗人r血清出现沉淀线,其中XM—H—A_2有两条带。这次获得的三个杂交瘤细胞系说明我们正在建立的杂种细胞分布板是一个很好的材料,同时对于急性粒细胞白血病的发病机制和采用单克隆抗体技术诊断和治疗白血病研究提供了有效手段。
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