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大鼠小肠移植
相关语句
  rat intestinal transplantation
     Comparison and Significance of Various Rat Intestinal Transplantation Models
     不同种系大鼠小肠移植模型的建立及意义
短句来源
     The operation of rat intestinal transplantation is very difficult. The technique is refined continually, but the postoperative mortality at early stage is still high.
     大鼠小肠移植手术难度较大 ,虽然在技术上进行了不断的改良 ,但术后早期死亡率仍然很高。
短句来源
     This paper will present the history and progress of rat intestinal transplantation models from the aspects of donor procedure, vascular anastomosis,intestinal anastomosis, reconstruction of lymphatic drainage, combined liver/intestine transplantation and compare the features of various models.
     本文从供体摘取、血管重建、消化道重建、淋巴管重建、肝肠联合移植等多个方面论述了大鼠小肠移植模型的沿革和发展 ,并对各种模型的特点进行了比较
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  “大鼠小肠移植”译为未确定词的双语例句
     Changes of CD45RC~+/CD45RC~- ratio in peripheral blood following small bowel transplantation in rats and significance
     大鼠小肠移植后外周血CD45RC~+细胞和CD45RC~-细胞比值的变化及意义
短句来源
     Combination of interleukin-12p35 silenced dendritic cells and anti-CD40L monoclonal antibody induces the immune tolerance of intestinal allograft in rats
     白细胞介素-12 p35沉默的树突状细胞联合CD40L单克隆抗体对大鼠小肠移植免疫耐受的诱导作用
短句来源
     Conclusions TGF-β1 can suppress the caute rejection of small intestinal allografts in rats.
     结论 TGF -β1可抑制大鼠小肠移植急性排斥反应
短句来源
     Results: The survival time in the groups of control,donor immature DC and donor immature DC +anti-CD40L mAb was(7.17 ± 1.47)days,(11 ± 2.61)days and(22.67 ± 7.09)days respectively.
     结果:A、B、C组大鼠小肠移植后平均存活时间分别为:(7.17±1.47)天(、11±2.61)天(、22.67±7.09)天。
短句来源
     Role of OX34 in treatment of acute rejection after small bowel transplantation in rats
     OX34预防大鼠小肠移植急性排斥反应
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  相似匹配句对
     Establishment of Small Bowel Transplantation Model in Rats
     大鼠小肠移植模型的建立
短句来源
     Surgical technique for intestinal transplantation in rats*
     大鼠小肠移植的外科技术
短句来源
     Improvement of the model of small bowel transplantation in rats
     大鼠小肠移植模型的改进
短句来源
     Prevention of complication of orthotopic intestinal transplantation in rats
     大鼠原位小肠移植并发症的预防
短句来源
     Advances in Small Intestinal Transplantation
     小肠移植进展
短句来源
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The experimental study of segmental Intestine transplantation in Rats were earried out from March to December 1991. The SBT Rat model has been successfully established. The operative survival rate was about 85% in formal experiments; the postoperative five-day survival rate nearly 80%.In this article, a series of problems which often appear in operation, such as bled vessel anastomosis, biopsis, observation after transplantation and their management have been discussed in detail.

1991年3~12月进行了121次大鼠小肠移植实验研究,已制造了稳定的动物模型。正式实验35次中,手术成功率达85%,术后5天存活率近80%。对手术中遇到的一系列问题,如血管吻合、活检、术中保暖及术后观察等处理进行了探讨。

Rejection is a major obstacle to successful small bowel transplantation and is closely related with cellular immunity. T lymphocyte subsets in peripheral blood were assayed by immunofluorescence stain and flow cytometry after small bowel transplantation in rats. The results showed that there was an evident increase in CD4+ subset percentage during the early stage of rejection. And then, CD8+ subset declined and the ratio of CD4+/CD8+ elevated significantly There was a decrease in the ratio of CD4+/CD8+ in the...

Rejection is a major obstacle to successful small bowel transplantation and is closely related with cellular immunity. T lymphocyte subsets in peripheral blood were assayed by immunofluorescence stain and flow cytometry after small bowel transplantation in rats. The results showed that there was an evident increase in CD4+ subset percentage during the early stage of rejection. And then, CD8+ subset declined and the ratio of CD4+/CD8+ elevated significantly There was a decrease in the ratio of CD4+/CD8+ in the late stage of rejection. These changes were not discovered in CsA treated group. The present study demonstrate that both CD4+ and CD8+ cells participate in reJectlon in small bowel transplantation, and the changes of CD4+ /CD8+ ratio indicate both the state of cellular immunlty and the stage of rejection.

利用免疫荧光染色技术及流式细胞仪对大鼠小肠移植后外周血T淋巴细胞亚群变化进行连续监测,以探讨细胞免疫功能变化在排斥反应中的意义。结果表明,排斥反应时首先出现CD4阳性细胞显著增高,随后出现CD8阳性细胞明显下降及CD4阳性细胞/CD8阳性细胞比值增高,在排斥反应后期其比值下降;使用环孢素A作免疫抑制的大鼠T淋巴细胞各亚群均无显著性变化。本实验证明CD4阳性细胞及CD8阳性细胞共同参与了排斥反应,根据二者比值的变化可判断受体的免疫状态和排斥反应的发展阶段。

In present study,T cell subsets in perpheral blood lymphocyte(PBL)of rats which had received small bowel transplantation and in graft infiltrating lymphocyte(GIL)of transplanted small bowel were assayed by flow cytometry and image cytometry- Simuitaneously,the grafts were observed histopatholo- gically. The results showed that CD4+ cells in PBL of those two groups without cyclosoorine A(CsA) increased respectively on postoperative day(POD)5 and POD 10,as well ss CD8+ cells in GIL enhanced on POD 5~7and POD 7~10....

In present study,T cell subsets in perpheral blood lymphocyte(PBL)of rats which had received small bowel transplantation and in graft infiltrating lymphocyte(GIL)of transplanted small bowel were assayed by flow cytometry and image cytometry- Simuitaneously,the grafts were observed histopatholo- gically. The results showed that CD4+ cells in PBL of those two groups without cyclosoorine A(CsA) increased respectively on postoperative day(POD)5 and POD 10,as well ss CD8+ cells in GIL enhanced on POD 5~7and POD 7~10. In the groups treated with CsA,there was decreasing of CD3+ subset in GIL. It was demonstrated that both CD4+ and CD8+ subsets cooperate to participate rejection, the increasing of CD4+ cells in PBL indicated the beginning of graft rejection, and the enhancement of CDs" cells in GIL forecasted the immunity damage in graft. The alteration of T lymphocyte subsets is helpful in the diagnosis to early stage rejection in small bowel transplantation.it could discover evidence of rejection 2 days earlier at least than pathologic examination-

利用流式细胞和图象分析技术对远交系大鼠小肠移植模型受体外周血淋巴细胞(PBL)和移植肠浸润淋巴细胞(GIL)的T细胞亚群进行连续测定,同时检查移植肠组织病理变化。结果表明:非环孢素A(CsA)治疗两组大鼠PBL分别于术后5天和10天出现CD_4~+细胞亚群显著升高,GIL分别在术后5天和7天出现CD_8~+细胞的浸润增多;CsA治疗组PBL无明显变化,术后7大GIL中CD_3~+细胞浸润减少。研究认为;CD_4~+及CD_8~+细胞共同参与排斥反应、协调发挥作用,PBL中CD_4~+细胞的升高预示着排斥反应的出现,GIL中CD_8~+细胞的增多标志着移植物局部免疫损伤的加剧。PBL、GIL连续监测较组织病理发现排斥提前2天以上,有助于临床小肠移植排斥反应的早期发现。

 
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