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期乳腺癌
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  primary breast cancer
     Research of clinical characteristics of 238 female patients with T_1 primary breast cancer
     238例女性T_1期乳腺癌临床特征分析
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     Results (1) The nm23 - H1 mRNA gene expression in primary breast cancer tissue with lymph node metastasis was lower than that without lymph node metastasis. The nm23 - H1 mRNA level in stage I and II breast cancer was higher than that in stage III.
     结果 ①淋巴结阳性的原发灶组织nm23-H1 mRNA表达明显低于淋巴结阴性的原发灶组织,Ⅲ期乳腺癌组织nm23-H1 mRNA水平较I、Ⅱ期的明显低.
短句来源
     Methods: During the period of 1973 to 1983, 765 patients with stage Ⅱ breast cancer were treated surgically. They accounted for 28.7% of 2665 cases of primary breast cancer treated at this hospital during the same period.
     方法:我院自1973年1月到1983年12月共手术治疗765例Ⅱ期乳腺癌,占经治可手术女性乳腺癌2665例的28.7%。
短句来源
     Role of fine needle aspiration cytology combined with mammography in diagnosis of T_1 primary breast cancer
     细针吸取组织学检查结合钼靶摄片在女性T_1期乳腺癌诊断中的应用
短句来源
     During the period of 1973-1983,253 patients with stage I breast cancer were treated by surgery. They accounted for 9.5% of 2665 cases of primary breast cancer treated at this hospital during the same period.
     我院自1973年到1983年底共手术治疗253例Ⅰ期乳腺癌,占经治可手术女性乳腺癌2665例的9.5%.
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  “期乳腺癌”译为未确定词的双语例句
     Another 5 peaks (M1701_48, M3116_17, M1676_88, M5890_33, M2921_02 m/z) could build the model Ⅲ to distinguish stage Ⅰ and stage Ⅱ~Ⅳ breast cancers. Its sensitivity and specificity were 88.9% (8/9) and 86.2% (25/29), respectively.
     质荷比分别为M1701_48、M3116_17、M1676_88、M5890_33和M2921_02的5个蛋白质峰组合的诊断模型Ⅲ,鉴别Ⅰ期与Ⅱ~Ⅳ期乳腺癌的交叉验证敏感性为88.9%(8/9),特异性为86.2%(25/29)。
短句来源
     Results BCSG1 was detected in 36.6% of all breast cancer samples (34/93). 76.5% (26/34) of BCSG1-positive cases was stage Ⅲ/Ⅳ.
     结果BCSG1在乳腺癌中表达率为36.6%(34/93),其中Ⅲ/Ⅳ期乳腺癌占76.5%(26/34)。
短句来源
     The model Ⅱ was formed by 5 protein peaks (M2251_62, M3405_56, M3428_16, M4666_98, M16239_8 m/z). When it was used in differential diagnosis between stage Ⅰ breast cancer and benign breast diseases, the sensitivity and specificity were 84.8% (28/33) and 55.6% (5/9), respectively.
     质荷比分别为M2251_62、M3405_56、M3428_16、M4666_98和M16239_8的5个蛋白质峰组合构建的诊断模型Ⅱ,鉴别Ⅰ期乳腺癌和乳腺良性疾病的交叉验证敏感性为84.8%(28/33),特异性为55.6%(5/9)。
短句来源
     According to TNM stages,the positive rates of HER2 protein expression in 1,2,3 stages were 48.57%(17/35), 70.73%(29/41) and(87.50%)(21/24),respectively. It was positively correlated to the clinical stage(P<0.05).
     按TNM分期可见,1、2、3期乳腺癌中HER2表达阳性率分别为48.57%(17/35)、70.73%(29/41)和87.50%(21/24),随着肿瘤的进展,HER2表达逐渐增强(P<0.05)。
短句来源
     A clinical analysis of 121 cases of breast cancer with stage T_2, T_3
     121例T_2、T_3期乳腺癌临床分析
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  相似匹配句对
     Breast Cancer During Pregnancy
     妊娠乳腺癌
短句来源
     Conclusion: No relation of stage II breast cancers was found between the long term result and the type of operation.
     结论:Ⅱ乳腺癌?
短句来源
     Chemoprevention of breast cancer
     乳腺癌的药物预防
短句来源
     the complete period;
     定型;
短句来源
     angulatus , early to middle P. deltifer and late P. deltifer to Serratognatus , are reconstructed.
     angulatus、P.
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  primary breast cancer
A multivariate analysis of 617 female patients with primary breast cancer treated by radical mastectomy between 1974 and 1981 was done.
      
Objective: The aim of this study was to detect micrometastases in bone marrow of primary breast cancer patients, and compare with other clinical parameters.
      
Methods: Applying streptavidin-biotin complex (SABC) immunohistochemical technique, expression of uPA was studied in 100 patients with primary breast cancer.
      
Methods: DNAs of tumor tissues and blood lymphocytes were collected from 40 cases of primary breast cancer patients and LOH were detected using the microsatellite repeat assay and combined with other ER immunohistochemical assays.
      
Objective: To evaluate the feasibility and activity of continuous-infusion of fluorouracil in association with epirubicin or pirarubicin and cyclophosphamine as neoadjuvant regimen in patients with primary breast cancer.
      
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In 1955-1978,1,091 cases of breast cancer were treated with extended radical mas-tectomy without operative death or a major complication.The overall axillary lymph-node metastatic rate was 50.69% and internal mammary lymphnode metastatic rate17.69%.The respective 5,10 and 20 years survival rates of stage Ⅰ patients were93.5%,88.2% and 82.5%,stage Ⅱ patients 80.6%,69.3%;and 63.3%;and stageⅢ patients 49.5%,41.3% and 37.2%.A comparison between the long term resultsof extended radical mastectomy and radical mastectomy(740...

In 1955-1978,1,091 cases of breast cancer were treated with extended radical mas-tectomy without operative death or a major complication.The overall axillary lymph-node metastatic rate was 50.69% and internal mammary lymphnode metastatic rate17.69%.The respective 5,10 and 20 years survival rates of stage Ⅰ patients were93.5%,88.2% and 82.5%,stage Ⅱ patients 80.6%,69.3%;and 63.3%;and stageⅢ patients 49.5%,41.3% and 37.2%.A comparison between the long term resultsof extended radical mastectomy and radical mastectomy(740 cases in the same period)showed no difference in stage Ⅰ patients,but in stage Ⅱ and Ⅲ patients extended ra-dical mastectomy was superior to radical mastectomy.The authors point out that if thereis internal mammary lymphnodes metastasis,best results are obtained by extended radi-cal mastectomy.

本文报道乳腺癌扩大根治术1,091例,无手术死亡或严重并发症。全组腋淋巴结转移率50.69%,乳内淋巴结转移率17.69%.全组Ⅰ期乳腺癌的五年、十年、廿年生存率为92.46%、88.15%、82.46%,Ⅱ期为80.58%、69.25%、63.32%,Ⅲ期为49.50%、41.31%、37.54%。与同期施行的740例根治术相比,Ⅰ期病人的生存率两者无显著差异,而Ⅱ、Ⅲ期病人则扩大根治术的生存率显著地高于根治术者。作者认为,扩大根治术可适用于各期(尤期是Ⅱ、Ⅲ期)浸润性癌。

During 1954-1972, 157 patients with stage I breast cancer were treated by surgical procedures. In 31 cases the tumors were ≤1 cm in greatest diameter, and in 126 cases >1 cm-≤2 cm. Simple mastectomy was done in 4 cases. Halsted radical mastecto- my in 94, extended radical mastectomy in 14, and modified radical mastectomy in 45. 1/5 of No cases and 1/3 of N_1a cases were of positive pathology. The 5-year rate of NED* in this series was 86%, and the 10-year rate 76.3%. The 10-year NED rate of specific type of...

During 1954-1972, 157 patients with stage I breast cancer were treated by surgical procedures. In 31 cases the tumors were ≤1 cm in greatest diameter, and in 126 cases >1 cm-≤2 cm. Simple mastectomy was done in 4 cases. Halsted radical mastecto- my in 94, extended radical mastectomy in 14, and modified radical mastectomy in 45. 1/5 of No cases and 1/3 of N_1a cases were of positive pathology. The 5-year rate of NED* in this series was 86%, and the 10-year rate 76.3%. The 10-year NED rate of specific type of carcinoma (92%) was much better than non- specific type (68%) (P<0.01). A significant statistical difference in 10-year cure ra- tes of the three types of operation was not discernible, as the number of patients in each group was small. According to our experience, Certain types of stage I breast cancer, such as papi- llary cystic adenocarcinoma, typical medullary carcinoma, non-infiltrative intraductal carcinoma, lobular carcinoma in situ, Paget′s disease of the nipple without duct car- cinoma in breast tissue, and early carcinomatous change in cystic hyperplasia, simple mastectomy appears to be sufficient. In other types of breast cancer, modified radical mastectomy may be the treatment of choice.

I期乳腺癌系指T_1N_0-laMo的乳腺癌而言。我院自1954到1972年共手术治疗157例I期乳腺癌,其中~1cm者31例,1~+~2cm者126例。行单纯全乳切除术4例,Halsted根治术94例,扩大根治术14例和改良根治术45例。临床为N_0者约1/5腋淋巴结阳性,N_1a者约1/3病理阳性。157例的5年健在率86%,156例的10年健在率为76.3%。特殊型癌的10年健在率为92%,明显优于非特殊型癌的68%(P<0.01)。因本组例数较少,故三种术式的10年疗效未见明显的统计学差异。本组经验认为某些Ⅰ期乳腺癌(如乳头状囊腺癌、典型髓样癌、无管外浸润的管内癌、无乳腺实质腺癌的乳头湿疹样癌、小叶原位癌和囊性增生病早期癌变等)可仅行单纯全乳切除术,其它则宜行改良根治术。

Three hundred and three cases of premenopausal operable breast cancer patients (166 Stage Ⅰ-Ⅱ and 137 Stage Ⅲ) were treated by curative mastectomy and prophy- lactic castration, and in the same period, 368 cases (251 Stage Ⅰ-Ⅱ and 117 Stage Ⅲ) of similar condition were treated only by curative mastectomy as control. In Stage Ⅰ-Ⅱ without aaillary lymph-node matastasis group, the 10-pear rate of NED in cas- tration group (43 cases) was much better than that of the control group (165 cases) (P<0.01) In aaillary...

Three hundred and three cases of premenopausal operable breast cancer patients (166 Stage Ⅰ-Ⅱ and 137 Stage Ⅲ) were treated by curative mastectomy and prophy- lactic castration, and in the same period, 368 cases (251 Stage Ⅰ-Ⅱ and 117 Stage Ⅲ) of similar condition were treated only by curative mastectomy as control. In Stage Ⅰ-Ⅱ without aaillary lymph-node matastasis group, the 10-pear rate of NED in cas- tration group (43 cases) was much better than that of the control group (165 cases) (P<0.01) In aaillary lymph-node positive group, the 10-year result group (123 cases) was better than the control (86 cases) (P>0.05), but only in 1-3 positive node group, the statistical difference being significant between the castration (68 cases) and the control (47 cases) P<0.05. In Stage Ⅲ (N_0-1 breast cancer with or without lymph-node metastasis, the 10-year results of castration group were better, but without statis- tical significance. In Stage Ⅲ (N_2 cases, prophylactic castration did not improve the survival rate.

本文总结303例可手术治疗的闭经前乳腺癌患者,除行治愈性乳腺切除外,尚行预防性去势治疗。同期相似病例368例,仅行治愈性乳腺切除术而未行去势治疗者做为对照。Ⅰ~Ⅱ期患者,腋淋巴结阴性时,去势组的10年健在率明显优于对照组(P<0.01),按逐年健在率比较,则此种优势于术后7~8年开始明显,按各种辅助治疗类别分项比较,去势组的优势与术后辅助治疗无关。腋淋巴结阳性患者去势组的10年健在率亦优于对照组(P>0.05),但仅淋巴结为1~3个阳性时有统计学的差异(P<0.05)。Ⅲ期乳腺癌N_(0-1)患者,腋林巴结无论有无转移,去势组的10年健在率皆优于对照组,但差异不显著;N_2患者行预防性去势并不能明显提高疗效。

 
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