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   多形性癌 的翻译结果: 查询用时:0.038秒
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多形性癌
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  pleomorphic carcinoma
     Clinical observation of lung pleomorphic carcinoma and review of literatures (report of 5 cases)
     肺多形性癌临床观察及文献复习(附5例报告)(英文)
短句来源
     Objective A clinicopathological study of 10 patients with pleomorphic carcinoma of the lung.
     目的 对 10例肺多形性癌回顾性临床病理研究 ,探讨肺多形性癌的临床病理特点。
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     [Methods] 5 patients (4 men, 1 woman; mean age 53.2 years; ranging 36~69 years) with pleomorphic carcinoma treated from Dec 2000 to Nov 2005 were collected and studied clinicopathologically.
     方法自2000年12月 ̄2005年11月,共5例肺多形性癌患者在该科进行治疗。 其中男性4例,女性1例,年龄36 ̄69岁,平均年龄53.2岁。
短句来源
     Results Of 20 cases, 15 cases were pleomorphic carcinoma(10 cases with adenocarcinoma,3 cases with large cell carcinoma,1 case with squamous cell carcinoma and 1 case with giant cell carcinoma),4 cases were spindle cell carcinoma, and 1 case was giant cell carcinoma.
     结果20例患者中,15例为多形性癌,其中10例伴腺癌成分,3例伴大细胞癌成分,1例伴鳞癌成分,1例伴巨细胞癌成分; 4例为梭形细胞癌;
短句来源
     Also, tumors in this group had 11 cases with cancerization of lobules, 7 cases with pleomorphic carcinoma component and 6 cases with apocrine carcinoma like change.
     11例伴有小叶癌化 ,7例有多形性癌成分 ,6例伴有大汗腺癌样改变。
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  “多形性癌”译为未确定词的双语例句
     Objective: To observe the expression and role of nm23-H1? PCNA and P53 protein in lung polymorphic cancer tissue.
     目的:探讨nm23-H1、PCNA、p53蛋白在肺多形性癌组织中的表达及意义。
短句来源
     66.7% and 75.0%? 83.3%and 25.0% respectively, In lung polymorphic cancer with and without invasive peripheral tissue, the posivive rates were 37.5% and 100%? 68.8% and 75.0%?
     PCNA在肺多形性癌有无淋巴结转移中阳性率分别为66.7%和75.0%,差异无显著性(P>0.05),在有无侵犯周围组织中阳性率各为68.8%和75.0%,差异无显著性(P>0.05);
短句来源
     68.8% and 25.0% resptctively , The nm23-H1 and P53 had obvious difference (P <0.01), but PCNA had not difference (P >0.05).
     p53在肺多形性癌有无淋巴结转移中阳性率分别为83.3%和25.0%,差异有显著性(P<0.01),在有无周围组织中阳性率各为68.8%和25.0%,差异有显著性(P<0.01)。
短句来源
     The expression of nm23-H1 and P53 were closely related with the lymphatic metastasis?
     Nm23-H1、p53基因表达与肺多形性癌淋巴结转移、侵袭力及预后有关。
短句来源
     Methods Histopathological and immunohistochemical staining for keratin, vimentin, Mac387, desmin, actin and S-100 protein were used for this study.
     方法 采用组织病理学、免疫组织化学SP法标记 (角蛋白、波形蛋白、Mac387、结蛋白、肌动蛋白、S 10 0蛋白 )对 10例肺多形性癌进行研究。
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  相似匹配句对
     Temporal bone carcinoma
     颞骨
短句来源
     Pancreatic Cancer
     胰
短句来源
     Pleomorphic Lipoma
     多形性脂肪瘤
短句来源
     [Objective] To retrospectively evaluate the clinical feature of pleomorphic carcinoma and analyze prognosis-related factors.
     目的观察肺多形性临床特征,分析影响预后因素。
短句来源
     Clinical observation of lung pleomorphic carcinoma and review of literatures (report of 5 cases)
     肺多形性临床观察及文献复习(附5例报告)(英文)
短句来源
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  pleomorphic carcinoma
Pleomorphic carcinoma of the pancreas with osteoclast-like giant cells
      
We studied two cases of pleomorphic carcinoma of the pancreas with osteoclast-like giant cells.
      
A case of pleomorphic carcinoma of the pancreas showing sequential histological change by immunohistochemical study
      
Pleomorphic carcinoma of the pancreas is a rare, histologically characterized pancreatic tumor with a rapid and fatal course.
      
We report a case of a resected pleomorphic carcinoma located in the body of the pancreas in a 61-yr-old male.
      
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  pleomorphic neoplasm
Histology revealed a highly pleomorphic neoplasm with extensive zones of necrosis.
      


Objective A clinicopathological study of 10 patients with pleomorphic carcinoma of the lung. Methods Histopathological and immunohistochemical staining for keratin, vimentin, Mac387, desmin, actin and S-100 protein were used for this study. Results Pleomorphic carcinoma of the lung was found to often occurr in males above 50 years of age and with clinical symptoms including cough, expectoration, haemoptysis and chest pain. The most frequent microscopic dignosis was squamous cell carcinoma, and adenocarcinoma,...

Objective A clinicopathological study of 10 patients with pleomorphic carcinoma of the lung. Methods Histopathological and immunohistochemical staining for keratin, vimentin, Mac387, desmin, actin and S-100 protein were used for this study. Results Pleomorphic carcinoma of the lung was found to often occurr in males above 50 years of age and with clinical symptoms including cough, expectoration, haemoptysis and chest pain. The most frequent microscopic dignosis was squamous cell carcinoma, and adenocarcinoma, accompanied by spindle and giant cells. The epithelial component of pleomorphic carcinoma of the lung displayed positivity for keratin and the spindle cells displayed positivity for vimentin. In some cases the neoplastic epithelial component and spindle cells showed positive expression of both keratin and vimentin. Conclusion Pleomorphic carcinoma of the lung may display various histopathological changes making it easy to be misdiagnosed as carcinosarcoma. Understanding its pathogenesis and histopathology is important for the diagnosis and differential diagnosis.

目的 对 10例肺多形性癌回顾性临床病理研究 ,探讨肺多形性癌的临床病理特点。方法 采用组织病理学、免疫组织化学SP法标记 (角蛋白、波形蛋白、Mac387、结蛋白、肌动蛋白、S 10 0蛋白 )对 10例肺多形性癌进行研究。结果 肺多形性癌多见于 5 0岁以上的男性 ,临床首发症状咳嗽、咳痰、咯血或患侧胸痛 ,镜下以鳞癌、腺癌等成分为主 ,伴有多少不等的梭形细胞或 (和 )巨细胞成分。肿瘤的上皮成分表达角蛋白 ,梭形细胞表达波形蛋白 ,3例上皮及梭形细胞成分同时表达角蛋白及波形蛋白。结论 肺多形性癌具有多种病理组织形态特征 ,病理诊断上易与癌肉瘤混淆。明确该肿瘤的组织发生 ,对于诊断及鉴别诊断有重要意义。

Purpose To explore the clinicopathological features of pleomorphic carcinoma of the pancreas with osteoclast-like giant cells(PCOG). Methods The clinical data, pathologic changes and immunohistochemical findings in one case of PCOG were observed with review of the literature. Results The patient was a 58-year-old female who developed constant, intermittent upper quadrant hidden pain. An abdominal ultrasonographic and computed tomographic scan demonstrated a 9 cm mass which appeared to arise from the body...

Purpose To explore the clinicopathological features of pleomorphic carcinoma of the pancreas with osteoclast-like giant cells(PCOG). Methods The clinical data, pathologic changes and immunohistochemical findings in one case of PCOG were observed with review of the literature. Results The patient was a 58-year-old female who developed constant, intermittent upper quadrant hidden pain. An abdominal ultrasonographic and computed tomographic scan demonstrated a 9 cm mass which appeared to arise from the body and tail of the pancreas. The resected speciman showed nodular, firm, whitish yellow, and focally necrotic. Histologically, the tumor was composed of poorly differentiated adenocarcinoma cells intermixed with spindle sarcoma-like cells, both cells showed cytokeratin, vimentin, and alpha-1-antitrypsin positive immunostain. More striking were many area of the tumor resembling giant cell tumor of bone, which were composed of polygonal mononuclear cells and morphologically benign osteoclast-like giant cells, the former displayed immunoreactivity for vimentin, alpha-1-antitrypsin, and sparse immunoreactivity for cytokeratin, the latter displayed immunoreactivity only for CD68 and vimentin. Conclusions PCOG is a variant of pleomorphic carcinoma of pancreas. The osteoclast-like giant cells seen in the tumor are regarded as reactive, not neoplastic component.

目的 探讨含破骨巨细胞样细胞的胰腺多形性癌的临床病理特征。方法 对 1例含破骨巨细胞样细胞的胰腺多形性癌进行临床、病理组织学和免疫组织化学观察。结果 患者为 5 8岁女性 ,因中上腹部持续性隐痛 2个月余就诊 ,B超、CT检查发现胰腺占位。切除标本示实性结节状肿块 ,灰白、灰黄色 ,有灶性坏死。镜下见肿瘤由低分化腺癌伴梭形肉瘤样细胞构成 ,两种细胞均示CK、Vim、α AT阳性。可见多灶性巨细胞瘤样结构 ,由单核瘤细胞和形态上良性的破骨巨细胞样细胞构成 ;前者见CK散在阳性 ,Vim和α AT阳性 ;后者仅见CD6 8和Vim阳性。结论 含破骨巨细胞样细胞的胰腺多形性癌是多形性胰腺癌的一种亚型 ,破骨巨细胞为反应性细胞 ,非肿瘤成分。

Purpose To study the clinicopathological features and the immunohistochemical phenotypes of pregnancy associated breast cancer (PABC) and breast cancer with pregnancy like change (BCPLC). Methods Eighteen cases of PABC and 9 cases of BCPLC,chosen from 1 050 cases of breast carcinoma, were observed for the histopathological features and immunohistochemically stained by PV9000 method. Results In PABC group, the tumors varied between 1 5 and 6 0 cm(mean 3 8 cm) in the greatest dimension of the tumors,...

Purpose To study the clinicopathological features and the immunohistochemical phenotypes of pregnancy associated breast cancer (PABC) and breast cancer with pregnancy like change (BCPLC). Methods Eighteen cases of PABC and 9 cases of BCPLC,chosen from 1 050 cases of breast carcinoma, were observed for the histopathological features and immunohistochemically stained by PV9000 method. Results In PABC group, the tumors varied between 1 5 and 6 0 cm(mean 3 8 cm) in the greatest dimension of the tumors, 13 cases(84 6%) had axillary lymph node metastasis, and there were 16 cases of invasive duct carcinoma and 2 cases of mucinous carcinoma. Also, tumors in this group had 11 cases with cancerization of lobules, 7 cases with pleomorphic carcinoma component and 6 cases with apocrine carcinoma like change. In BCPLC group, of which all cases were invasive duct carcinoma and all had axillary lymph node metastasis. The tumors varied between 1 5 and 9 0 cm (mean 4 9cm) in greatest dimension of the tumors, and there were 7 cases with cancerization of lobules and 2 cases with apocrine carcinoma like change. The tumors of the PABC and BCPLC were positive for E cadherin (both 100%), p53 (both 66 7%), ER (40 0% and 77 8%), PR(21 4% and 44 4%), c erbB 2 (46 7% and 44 4%), bcl 2 (44 0% and 55 5%) and EGFR (35 7% and 22 2%), respectively. The mean scores of Ki 67 staining in tumors of the both groups were 46 87% and 39 63%. Conclusions The findings of this study suggest the tumors of PABC and BCPLC have certain characteristics in morphology including that most of them are invasive duct carcinoma and have cancerization of lobules, and they have higher incidence of lymph node metastasis and lower incidence of PR expression, which should be a poor prognosis.

目的 探讨妊娠相关性乳腺癌和伴妊娠样改变的乳腺癌病理组织学特点及其免疫表型。方法 从 10 5 0例乳腺癌病理资料中查出全部妊娠相关性乳腺癌 18例和伴有妊娠样改变的乳腺癌 9例 ,详细观察HE切片的组织形态学特点 ,用PV90 0 0二步法进行免疫组化染色。结果 妊娠相关性乳腺癌肿瘤直径 1 5~ 6 0cm (中位数 3 8cm) ,淋巴结转移率为84 6 % ;16例为浸润性导管癌 ,2例为黏液癌 ;11例伴有小叶癌化 ,7例有多形性癌成分 ,6例伴有大汗腺癌样改变。伴泌乳样改变的乳腺癌全部为浸润性导管癌 ,肿瘤直径 1 5~ 9 0cm(中位数 4 9cm) ,淋巴结转移率 10 0 % ;有小叶癌化者 7例 ,2例伴有大汗腺癌样改变。免疫组化两者均 10 0 %表达E cadherin ,6 6 7%表达 p5 3,表达ER分别为 4 0 0 %和 77 8% ,PR分别为2 1 4 %和 4 4 4 % ,c erbB 2分别为 4 6 7%和 4 4 4 % ,bcl 2分别为 4 0 0 %和 5 5 5 % ,EGFR分别为 35 7%和 2 2 2 % ...

目的 探讨妊娠相关性乳腺癌和伴妊娠样改变的乳腺癌病理组织学特点及其免疫表型。方法 从 10 5 0例乳腺癌病理资料中查出全部妊娠相关性乳腺癌 18例和伴有妊娠样改变的乳腺癌 9例 ,详细观察HE切片的组织形态学特点 ,用PV90 0 0二步法进行免疫组化染色。结果 妊娠相关性乳腺癌肿瘤直径 1 5~ 6 0cm (中位数 3 8cm) ,淋巴结转移率为84 6 % ;16例为浸润性导管癌 ,2例为黏液癌 ;11例伴有小叶癌化 ,7例有多形性癌成分 ,6例伴有大汗腺癌样改变。伴泌乳样改变的乳腺癌全部为浸润性导管癌 ,肿瘤直径 1 5~ 9 0cm(中位数 4 9cm) ,淋巴结转移率 10 0 % ;有小叶癌化者 7例 ,2例伴有大汗腺癌样改变。免疫组化两者均 10 0 %表达E cadherin ,6 6 7%表达 p5 3,表达ER分别为 4 0 0 %和 77 8% ,PR分别为2 1 4 %和 4 4 4 % ,c erbB 2分别为 4 6 7%和 4 4 4 % ,bcl 2分别为 4 0 0 %和 5 5 5 % ,EGFR分别为 35 7%和 2 2 2 % ,Ki 6 7平均阳性指数为 4 6 87和 39 6 3。结论 妊娠相关性乳腺癌和伴妊娠样改变的乳腺癌在组织形态上有一定特点 ,主要发生于导管癌 ,两者都有较高的小叶癌化率 ;淋巴结转移率都很高 ,PR的表达率较低 ,提示预后不好。

 
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