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电迷宫
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  electric maze
     RESULTS The learning and memory abilities of rats by lateral ventricle injection with β-AP_ 23-35 significantly weakened compared with those in the saline group through 8-arm radial electric maze test ( P <0.05) and step-down passive avoidance test ( P <0.01).
     结果与溶剂组大鼠相比,模型大鼠八臂电迷宫错误次数明显增加(P<0.05),跳台学习和记忆错误次数明显增加(P<0.01)。
短句来源
     The electric maze indicator had positive correlation with P3-like potentials.
     正常大鼠类P3与电迷宫条件反射有相关性。
短句来源
     Method Rat`s model of AD was induced by peritoneal injection of AlCl 3 .Performance of learning and memory was tested in Y electric maze. Expression of APP 695 mRNA level in cerebral cortice was me asured by RT-PCR.
     方法用长期腹腔注射AlCl3复制大鼠动物模型,用RT-PCR检测端脑皮质beta-淀粉样前体蛋白mRNA异构体-APP695mRNA水平,用Y电迷宫仪检测大鼠的学习记忆能力。
短句来源
     Methods Two month old BALB/c mice were separately irradiated by millimeter wave with frequencies of 37.4 ~60 GHz at power densities of 1~8 mW/cm 2 for 2 h daily from 6th to 15th day of gestation. The test of learning capacity and memory of the adult offspring was employed on Y type electric maze. The contents of monoamine transmitter in the brain of the fetuses at term,adult offspring were measured by using HPLC ECD.
     方法用37.4~60GHz、功率密度1~8mW/cm2的毫米波,在小鼠怀孕6~15d时进行2h/d辐射,用电迷宫对子鼠进行学习记忆功能测试,用高效液相色谱电化学检测(HPLCECD)对子鼠脑单胺递质进行测定。
短句来源
     The test of learning capacity and memory in rats was undertaken on Y_type electric maze.
     3h/d。 30d后用Y型电迷宫测定大鼠学习记忆能力 ,随后处死取海马制成切片 ,电镜观察海马结构。
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  y maze
     Results NO and SS of hippocampus decreased(P<0.01) and Y maze test times increased(P<0.01) significantly after the microinjection of L NA. The level of NO was positively correlated with that of SS,and the content of NO and SS were negtively correlated with test times of learning and memory respectively.
     结果 海马微量注射 L - NA组大鼠与生理盐水对照组和正常对照组比较 ,海马中 NO、SS含量明显下降 (P<0 .0 1) ,Y型电迷宫测试次数明显增加 (P <0 .0 1) ,L - NA组大鼠海马 NO水平和SS水平呈显著正相关 ,NO、SS水平均与 Y型电迷宫测试次数呈显著负相关。
短句来源
     Changes of cytochrome C in hippocamp CA1 subregion were observed 24 hours after global brain ischemia and rat’s learning and memory abilities were examined with Y maze and elected voltage 40V at 4 weeks after the model operation.
     观察缺血后24h海马CA1区细胞色素C(CytC)变化,缺血后4周利用Y型电迷宫进行大鼠学习和记忆能力测试,选用电压40V。
短句来源
     Methods Nitric acid redactase and radioimmunity method are taken to detect the content of NO and SS in rat hippocampus after N ω nitro L arginine (L NA),a nitric oxide synthase (NOS) inhibitor,microinjected into hippocampus,and Y maze is used to observe the changes of capability of learning and memory,and a correlative analysis is made.
     方法 大鼠海马微量注射一氧化氮合酶 (NOS)抑制剂 N-ω-硝基 - L -精氨酸 (N -ω- Nitro- L - Arginine,L - NA )后采用 Y型电迷宫观察大鼠学习记忆能力的改变 ,以硝酸还原酶法测定海马 NO含量 ,以放射免疫法测定海马 SS含量 ,并进行学习记忆能力、NO含量和 SS含量相关性分析。
短句来源
     To assess the activity of VD rats after operation, measure their memory abilities by model Y maze 48 hours after reperfusion, observe the pathological changes of their cerebral histology and measure the expression of protein BCL-2, BAX, HSP70, P53 with immunohistochemistry method.
     术后进行运动功能评估、再灌注48h用Y型电迷宫检测其记忆能力,观察脑组织的病理学变化,并用免疫组织化学方法检测BCL-2、BAX、HSP70、P53蛋白的表达。
短句来源
     To establish the model of memory obtain induced by scopolamine and memory strengthen induced by sub sodium nitrite, Y maze test and step down test were used to determine the same indexes.
     建立东莨菪碱记忆获得障碍模型及亚硝酸钠记忆巩固障碍模型 ,采用一次性训练的空间辨别反应实验 -电迷宫实验和一次性学习的回避性条件反射试验 -跳台试验测定小鼠记忆功能 ,观察Hup-ATDDS对其影响。
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  “电迷宫”译为未确定词的双语例句
     RESULTS:(1)The neurological score and the study- remembrance score(N represents number of time when the rat learn standardization ,A/10 represents rate of retention of memory ) after ischmia 3 hours and reperfusion 24h (I 3h / R 24h) was 0, 47.5±7.1, 0.91±0.08 in the sham operation;
     结果:(1)缺血3h再灌注24h后神经功能缺陷计分及Y-电迷宫测试大鼠学习记忆能力(N代表学会标准时的训练次数;A/10代表记忆保持率): Sham组: 0分,N为47.5±7.1 , A/10为0.91±0.08;
短句来源
     Methods: A total of 32 rats were randomly divided into experimental and control groups and given alumen at concentrations of 0.10 g/kg, 0.42 g/kg, and 1.00 g/kg, and normal saline, respectively.
     方法将32只Wistar大鼠随机分为对照组(生理盐水)、白矾低(0.10g/kg)、中(0.42g/kg)、高(1.00g/kg)剂量组,每组8只,每d灌胃给药,用药1周后行电迷宫试验,2个月后行水迷宫试验。
短句来源
     Results: Compared with control group, the error rates were higher in electrical maze test (P<0.05 or 0.01), the latencies were longer (P<0.05 or 0.01), and the neuronal density in hippocampal CA1 decreased in experimental groups (0.42 g/kg and 1.00 g/kg alumen) (P<0.05).
     结果和对照组相比,中、高剂量白矾组电迷宫试验寻找安全区出错的几率增加(P<0.05或0.01),中、高剂量白矾组水迷宫试验中寻找平台潜伏期延长(P<0.05或0.01),皮层组织学分级升高、CA1区神经元密度降低(P<0.05)。
短句来源
     ② Y-maze test: Forty Kunming mice were randomly divided into saline group, ethanol group, ALEC high, mid-dle and low dosage groups with 8 mice in each group.
     ②Y型电迷宫法:取昆明种小鼠40只,随机分为生理盐水组、乙醇组、亚力克高、中和低剂量组5组,每组8只。
短句来源
     Methods With the administration of L ω nitro L arginine(L NA) into bilateral hippocami,the rat model with disorders of learning and memory abilities was established.
     方法 大鼠双侧海马注入N ω 硝基 L 精氨酸 (L NA)建立学习记忆障碍模型 ,注完L NA后再给大鼠腹腔内注射尼莫地平 ,用Y型电迷宫进行学习记忆能力测试。
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  y maze
Rats given posttrial injections of pentylenetetrazole and strychnine showed improved learning of a brightness discrimination in a simple Y maze.
      
Rats were trained to shuttle between two selected ("ON") arms of a Y maze, to obtain electrical stimulation of the medial forebrain bundle.
      
Rats were trained in a Y maze on a two-choice simultaneous brightness discrimination with light as S+ and dark as S- (position irrelevant).
      
The mice received, 20 min after training, an IP injection of either diazepam (2 mg/kg) or saline; half of the mice in each treatment group were exposed, 40 min after avoidance training (and 20 min after the injections) to a Y maze.
      
Exposure to the Y maze disrupted retention of the avoidance task in the saline-treated animals, and enhanced it in the diazepam-treated mice.
      
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In this article mice were irradiated with 36.11 GHz millimeter microwave at power density 7.2mW/cm~2 for 2 hours daily from the 6th to 15th day of gestation. We evaluated the following listed item with postnatal psychophysiological markers of the litter. The findings showed that: under the low power density millimeter microwave radiation, the litters appeared to have no alteration of physiological markers of pinna detachment, eye opening, testes descent, vaginal opening as well as early reflex makers of surface...

In this article mice were irradiated with 36.11 GHz millimeter microwave at power density 7.2mW/cm~2 for 2 hours daily from the 6th to 15th day of gestation. We evaluated the following listed item with postnatal psychophysiological markers of the litter. The findings showed that: under the low power density millimeter microwave radiation, the litters appeared to have no alteration of physiological markers of pinna detachment, eye opening, testes descent, vaginal opening as well as early reflex makers of surface righting, air righting, auditory startle. In these test, we also found no obvious effect on swimming endurance of matured offspring. The body weight of offspring decresed temporarily but it showed no difference between radiation and control group one week later. Millimeter microwave radiation can cause decreased learning capacity and memory of the matured offspring. They need more training and appeared to have more erroneous frequency than the control group irt order to get the stipulated criteria in conditional reflex test of Y-type electric maze.These results indicate that exposure to millimeter microwave radiation at low power density on the postimplantation embryos may result in subtle long-term neurophysiologic alteration.

本文用频率36.11GHz,功率密度为7.2mW/cm~2的毫米波,在小鼠怀孕6—15天时进行2小时/天的照射,用生后精神生理学指标进行分析。结果发现,未见导致胎仔生后耳廓张开、睁眼、睾丸下降、阴唇张开等生理指标的改变,也未使表面翻正、姿态纠正、听觉惊愕等早期反射指标发生变化,成熟仔鼠的游泳耐力亦未受明显影响。但可导致出生三天内的脍仔体重降低,一周后照射组胎仔体重与对照组无明显差别。毫米波辐射可导致成熟后仔鼠的学习及记忆能力降低,表现在Y型电迷宫条件反射实验中,需要较对照组鼠更多训练次数和错误次数才能达到规定标准。实验证明,低功率密度毫米波照射植入后期胚胎可引起仔鼠精细的精神生理学方面的改变。

Dipfluzine {1-diphenyl methyl-4-[4-(p-fluorophenyl)-4-oxobutyl]-piperazine, Dip} is a new derivative of cinnarizine (Cin). The improving effects of Dip on the amnesia induced by sodium nitrite and sodium pentobarbital in mice were studied using a step-down test and an electric maze method respectively. Dip improved sodium nitrite-induced impairment of the retention of memory in the step-down test, which was similar to Cin, and improved sodium pentobarbital-induced impairment of the orientation in the electric...

Dipfluzine {1-diphenyl methyl-4-[4-(p-fluorophenyl)-4-oxobutyl]-piperazine, Dip} is a new derivative of cinnarizine (Cin). The improving effects of Dip on the amnesia induced by sodium nitrite and sodium pentobarbital in mice were studied using a step-down test and an electric maze method respectively. Dip improved sodium nitrite-induced impairment of the retention of memory in the step-down test, which was similar to Cin, and improved sodium pentobarbital-induced impairment of the orientation in the electric maze test in mice significantly. In the doses of 20 and 40 mg·kg-1, both Dip and Cin significantly decreased the error times of mice and the percentage of the animals showing errors (P<0.05 and P<0.01 respectively, compared with the solvent control) in the step-down test, but 10 mg·kg-1 of both drugs did not. In the electric maze test 20 mg ·kg-1 of Dip increased the times of the correct response of mice significantly in d 1 and d 2 of training (P<0.05, compared with the solvent control), but 10 mg·kg-1 of Dip did not. At the effective dose (20 mg·kg-1) of influencing memory, Dip made the duration (32.2± s 6.6 s) of breathing movement with the mouth opened after the decapitation longer than that of the solvent control (20.2± s 3.8 s) significantly (P<0.01), and thus protected mice against the acute cerebral hypoxia.

用跳台法和电迷宫法,观察双苯氟嗪(dipfluzine)对亚硝酸钠和戊巴比妥钠造成的小鼠记忆障碍的改善作用,双苯氟嗪可明显改善亚硝酸钠引起的小鼠记忆障碍和戊巴比妥钠造成的小鼠方向辨别的获得障碍,且有剂量关系,20和40mg·kg~(-1)双苯氟嗪使小鼠跳台错误次数和出现跳台错误动物的百分率均显著低于溶剂对照组.20 mg·kg~(-1)双苯氟嗪使小鼠在训练的d1和d2受到电刺激后的正确逃避反应数均显著高于溶剂对照组(P<0.05).双苯氟嗪改善亚硝酸钠引起的小鼠记忆障碍的作用与桂利嗪(cinnarizine)相似,在改善记忆的有效剂量(20mg·kg~(-1))下,双苯氟嗪还有抗小鼠急性脑缺氧作用,使断头后小鼠张口呼吸动作持续时间(32±s7s)显著长于溶剂对照组(20±s4s,P<0.01).

The Sprague-Dawley rats withpostnatal 3 d were collected.The hypetpheny-lalaninemia was induced by intraperitoneal in-jection with phenylalanine.Fluorospec-trophotometry was applied to quantive determination of norepinephrine(NE),dopamine(DA)and serotonin(5-HT)in the cerebralcortex and its synaptosome of the rats. Beha-vior in the rats was observed by Y-maze learn-ing.The results showed that compare withthe control,the contents of NE,DA and 5-HT were decreased over 38.6%~67.4% inthe cortex of the hyperphenylalaninemic...

The Sprague-Dawley rats withpostnatal 3 d were collected.The hypetpheny-lalaninemia was induced by intraperitoneal in-jection with phenylalanine.Fluorospec-trophotometry was applied to quantive determination of norepinephrine(NE),dopamine(DA)and serotonin(5-HT)in the cerebralcortex and its synaptosome of the rats. Beha-vior in the rats was observed by Y-maze learn-ing.The results showed that compare withthe control,the contents of NE,DA and 5-HT were decreased over 38.6%~67.4% inthe cortex of the hyperphenylalaninemic ratsand decreased over 51.9%~70.2%in thesynaptosome of the cortex.Y-maze learningability in the rats was decreased apparently.The results suggest that the mental retarda-tion of PKU is in close correlative with de-crease of some monoamine transmitter con-tents in the cortex and its synaptosome.

以3d龄Sprague-Dawley大鼠腹腔注射苯丙氨酸(Phe)诱导高苯丙氨酸血症,荧光法测定大脑皮层及其突触体中去甲肾上腺素(NE)、多巴胺(DA)和5-羟色胺(5-HT)含量;Y型电迷宫法测其学习记忆能力.结果显示:高苯丙氨酸血症大鼠大脑皮层NE、DA及5-HT含量降低38.6%~67.4%,突触体中NE、DA和5-HT含量降低51.9%~70.2%,学习记忆能力明显低于对照组.结果提示,苯酮尿症智力障碍可能与大脑皮层及其突触体中某些单胺类递质含量降低相关.

 
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