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小儿原发性肾病综合征
相关语句
  children with primary nephrotic syndrome
    Changes of Tamm-Horsfall protein and β_2microglobulin level in children with primary nephrotic syndrome.
    小儿原发性肾病综合征Tamm-Horsfall蛋白与β_2微球蛋白水平改变的意义
短句来源
    Objective:To study the significance of TammHorsfall protein (THP) and β2microglobulin (β2MG) changes in children with primary nephrotic syndrome(PNS).
    目的:研究小儿原发性肾病综合征(PNS)Tamm-Horsfal蛋白(THP)与β2微球蛋白(β2MG)水平改变的意义。
短句来源
    OBJECTIVE To examine the changes of IL 13 in children with primary nephrotic syndrome(PNS) and to analyze the correlation between IL 13 and pathological types of childhood PNS.
    目的 :探讨白细胞介素 13 (IL 13 )在小儿原发性肾病综合征 (NS)中的变化及其与病理形态之间的关系。
短句来源
  children with idiopathic nephrotic syndrome
    The relationship between abnormal lipid and abnormal protein metabolism in children with idiopathic nephrotic syndrome
    小儿原发性肾病综合征脂质紊乱与蛋白代谢异常的关系
短句来源
    bjective To investigate the molecular mechanism of abnormal lipid in children with idiopathic nephrotic syndrome (INS).
    目的探讨小儿原发性肾病综合征(NS)脂质代谢紊乱机制。
短句来源
    bjective To study the relationship between abnormal lipid and abnormal protein metabolism in children with idiopathic nephrotic syndrome (INS).
    目的研究小儿原发性肾病综合征(INS)与蛋白代谢异常的关系。
短句来源
  “小儿原发性肾病综合征”译为未确定词的双语例句
    The different therapy of corticosteroid for children's primary nephrotic syndrome
    激素不同疗法治疗小儿原发性肾病综合征
短句来源
    Determination of apolipoprotein E polymorphism in children with idiopathic nephrotic syndrone by PCRSSCP
    PCR-SSCP法检测小儿原发性肾病综合征载脂蛋白E基因多态性
短句来源
    23 casesof child primary nephrotic syndrome we- re treated with hormone for a long course. Through six months to sixy ears of clinical observation,it was found that the elementary cure rate was 39.13%,the complete remission being 30.43% and the rate of reversal and relapse being 30%。
    使用激素长疗程治疗小儿原发性肾病综合征23例,经6个月至6年观察,基本治愈39.13%,完全缓解30.43%,反复和复发30%。
短句来源
    Objective To study the change of the plasma and urinary endothelin (ET) and nitric oxide (NO) in the children with primary nephritic syndrome (PNS) and their relationship.
    目的 探讨内皮素 (ET)、一氧化氮 (NO)在小儿原发性肾病综合征 (PNS)中的变化及相互关系。
短句来源
    Intraperitoneal Injection of Fetal Thymus for Reducing the Replapse of Idiopathic Nephrotic Syndrome
    胚胎胸腺腹腔注射减少小儿原发性肾病综合征复发的研究
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  children with primary nephrotic syndrome
Fifty-five Arab children with primary nephrotic syndrome (PNS) were seen at two regional hospitals in Kuwait over a 5-year period.
      
The study includes 150 children with primary nephrotic syndrome (NS), aged 16 months to 13 years with a median age of 5 years.
      
We report the SCE of peripheral blood lymphocytes in children with primary nephrotic syndrome (NS) treated with chlorambucil.
      
This retrospective case review of 43 children with primary nephrotic syndrome was designed to evaluate the relationship among renal ultrasound findings at presentation, subsequent corticosteroid responsiveness and histological diagnoses.
      
We conclude that increased renal echogenicity at time of presentation is a possible indicator of corticosteroid resistance in children with primary nephrotic syndrome.
      
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  children with idiopathic nephrotic syndrome
In a group of 16 children with idiopathic nephrotic syndrome treated with corticosteroids for longer than 12 months, 9 developed a posterior subcapsular cataract (PSC).
      
Impact of tuberculosis in children with idiopathic nephrotic syndrome
      
A preparation of extracts from the root of the Chinese medicinal herbTripterygium wilfordii Hook was administered orally at a dose of 1 mg/kg body weight per day to 13 children with idiopathic nephrotic syndrome.
      
Bone mineral density (BMD) was studied in 26 children with idiopathic nephrotic syndrome and in age-and sex-matched healthy controls.
      
There is a lack of reliable predictors of the response to alkylating agents in children with idiopathic nephrotic syndrome (NS).
      
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23 casesof child primary nephrotic syndrome we- re treated with hormone for a long course.Through six months to sixy ears of clinical observation,it was found that the elementary cure rate was 39.13%,the complete remission being 30.43% and the rate of reversal and relapse being 30%。The eathors believe that the loagcoarse treatment with hormone can reduce the rate of (?)ep(?)rosis relapses without apparent side-eff- ect. ect.

使用激素长疗程治疗小儿原发性肾病综合征23例,经6个月至6年观察,基本治愈39.13%,完全缓解30.43%,反复和复发30%。作者认为,激素长程疗法可减低肾病的复发率,且临床无明显副作用。

To study the characteristics of lipid metabolism in childhood primary nephrotic syndrome, we observed the changes in plasma lipid and lipoprotein in 20 primary nephrotic children aged 4 12 years (11 boys and 9 girls). Plasma total cholesterol (TC), low density lipoprotein C (LDL C), and lipoprotein(a) were obviously increased in all of the nephrotic children. The patients with both elevated TC and triglyceride (TG) had high very low density lipoprotein C (VLDL C) and low high density lipoprotein C...

To study the characteristics of lipid metabolism in childhood primary nephrotic syndrome, we observed the changes in plasma lipid and lipoprotein in 20 primary nephrotic children aged 4 12 years (11 boys and 9 girls). Plasma total cholesterol (TC), low density lipoprotein C (LDL C), and lipoprotein(a) were obviously increased in all of the nephrotic children. The patients with both elevated TC and triglyceride (TG) had high very low density lipoprotein C (VLDL C) and low high density lipoprotein C (HDL C) levels. There was a positive correlation between the quantity of 24hr proteinuria and plasma lipid (TC, TG and LDL C). We conclude that the changes in plasma lipids indicate the possible high risks of arteriosclerosis in nephrotic syndrome, especially in patients with both elevated TC and TG. The abnormalities of lipid metablism are related to the severity of proteinuria in nephrotic children.

为了解小儿原发性肾病综合征(NS)时脂代谢的特点,观察了20例原发性单纯型NS患儿的血脂、脂蛋白及载脂蛋白的变化。结果:(1)全部NS患儿血浆总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和脂蛋白(a)[Lp(a)]均明显升高;兼有TC、甘油三酯(TG)升高者,其极低密度脂蛋白胆固醇明显升高,高密度脂蛋白胆固醇明显降低。(2)NS患儿24小时尿蛋白定量与血浆TC、TG和LDL-C呈正相关(P<0.01)。提示:(1)NS患儿存在脂代谢异常,兼有TC、TG同时升高者,伴有更严重的脂蛋白及载脂蛋白的紊乱,存在着多种致动脉硬化及肾损伤的因素。(2)NS患儿脂代谢异常的程度与蛋白尿严重程度高度正相关。

bjective To investigate the molecular mechanism of abnormal lipid in children with idiopathic nephrotic syndrome (INS). Methods 7 lipoprotein metabolism parameters including serum TC, TG, HDLC, LDLC, ApoAI, ApoB and LP(a) of 68 children wiht INS as well as 120 age and sexmatched healthy children were determined. Singlestrand conformational polymorphism (PCRSSCP) were used to determine the ApoE genotypes of the patients and the types of urine protein were determined by urine protein sodium dodecylsulphate...

bjective To investigate the molecular mechanism of abnormal lipid in children with idiopathic nephrotic syndrome (INS). Methods 7 lipoprotein metabolism parameters including serum TC, TG, HDLC, LDLC, ApoAI, ApoB and LP(a) of 68 children wiht INS as well as 120 age and sexmatched healthy children were determined. Singlestrand conformational polymorphism (PCRSSCP) were used to determine the ApoE genotypes of the patients and the types of urine protein were determined by urine protein sodium dodecylsulphate polyacrylamide. Results All 7 parameters had no difference among the cases with Apo ε2, ε3 and ε4 allele genotypes (P>005), but serum TC, TG in Apo ε3/3 genotype cases with selectivity proteinuria (SPU) were higher than that in the same genotype cases with nonselectivity proteinuria (NSPU) significantly (P<005). Except that the Apo ε2 allele genotype frequency of NSPU cases was higher than that of healthy children significantly (1296% vs 5.00% P<0.05), the other ApoE allele genotype frequencies and genotype frequencies of INS group, SPU group or NSPU group had no difference from those of control group (P>005). Conclusion Abnormal lipid in childhood INS are mainly caused by their abnormal protein metabolism, and have no obviously relation with ApoE polymorphism, but NSPU cases with Apo ε2 allele genotypes have the possibility of progressive renal damage. 

目的探讨小儿原发性肾病综合征(NS)脂质代谢紊乱机制。方法测定了68例小儿NS及120例健康对照组7项血脂指标,采用聚合酶链反应-单链构象多态性(PCR-SSCP)技术检测其载脂蛋白E(ApoE)基因多态性。并采用SDS-PAGE检测NS组尿蛋白类型。结果所有7项指标在携不同ApoE等位基因(Apoε2、Apoε3及Apoε4)的患儿之间均无显著性差异(P>0.05),而携Apoε3等位基因型的选择性蛋白尿(SPU)组血总胆固醇(TC)、甘油三酯(TG)显著高于同型的非选择性蛋白尿组(NSPU)(P<0.05)。NSPU组的Apoε2等位基因频率显著高于健康儿童组(12.96%vs5.00%,P<0.05)。结论小儿原发性NS的脂质紊乱主要与其蛋白代谢异常有关而与ApoE基因多态性无明显关系。但携Apoε2等位基因的NSPU患儿有进行性肾脏损害的可能。

 
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