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   西酞普兰 在 精神病学 分类中 的翻译结果: 查询用时:0.022秒
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西酞普兰     
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  citalopram
Hier bieten sich als Alternative die Antidepressiva Trazodon und Citalopram an.
      
Citalopram in anxiety disorder of childhood and adolescence
      
Optimization and characterization of the chiral separation of citalopram and its demethylated metabolites by response-surface me
      
Response-surface modelling and sequential optimization have been used for optimization and characterization of the separation of the enantiomers of citalopram, desmethylcitalopram, and didesmethylcitalopram on an acetylated β-cyclodextrin column.
      
An on-line solid phase extraction-Liquid chromatography-Tandem mass spectrometry method for the analysis of citalopram, fluvoxam
      
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Objective:to investigate the anti depressive effect and adverse effect of a new selective serotonin re uptake inhibitor,citalopram Method:sixty patients with various depressive disorders were enrolled Hamilton Rating Scale of Depression(HAMD) and Clinical Global Impression (CGI)were used to evaluate the clinical response Result:among the 54 patients,who completed the 6 week treatment,69% were markedly improved according to CGI The rate of total improvement was 91% It showed some effect also on anxiety...

Objective:to investigate the anti depressive effect and adverse effect of a new selective serotonin re uptake inhibitor,citalopram Method:sixty patients with various depressive disorders were enrolled Hamilton Rating Scale of Depression(HAMD) and Clinical Global Impression (CGI)were used to evaluate the clinical response Result:among the 54 patients,who completed the 6 week treatment,69% were markedly improved according to CGI The rate of total improvement was 91% It showed some effect also on anxiety and sleep symptoms of depressive patients with mild adverse effects No patient dropped out for side effect Conclusion:the result suggested that citalopram was a safe and effective antidepressant

目的:观察选择性五羟色胺再摄取抑制剂西酞普兰的抗抑郁作用及其不良反应。方法:用该药治疗各种抑郁性障碍60例。用Hamilton抑郁量表和临床总体印象评定临床疗效。结果:在54例完成6周治疗的病人中,该药临床显效率达69%,总有效率为91%。对抑郁症病人所伴发的焦虑和睡眠障碍也有一定的治疗效果。不良反应轻微,无一例因药物不良反应导致治疗中断。结论:提示西酞普兰是一种安全有效的抗抑郁药物。

AIM:To compare the efficacy and adverse reactions of citalopram and amitriptyline in treating depression. METHODS:Eighty eight patients with depression(group A,M 36,F 52; age 32 a± s 7 a; disease duration 20 mo±6 mo) were treated with citalopram 22 mg±6 mg(20 40 mg·d 1 ), po . Another 87 patients with depression(group B, M34,F 53; age 31.2 a±2.3 a; disease duration 22 mo±4 mo) were treated with amitriptyline 100 mg±10 mg(50 150 mg·d 1 ), po , duration of treatment and within 1,2,4,6 wk...

AIM:To compare the efficacy and adverse reactions of citalopram and amitriptyline in treating depression. METHODS:Eighty eight patients with depression(group A,M 36,F 52; age 32 a± s 7 a; disease duration 20 mo±6 mo) were treated with citalopram 22 mg±6 mg(20 40 mg·d 1 ), po . Another 87 patients with depression(group B, M34,F 53; age 31.2 a±2.3 a; disease duration 22 mo±4 mo) were treated with amitriptyline 100 mg±10 mg(50 150 mg·d 1 ), po , duration of treatment and within 1,2,4,6 wk after treatment to measure the therapeutic efficacy. RESULTS: In the group A and B, the excellent effective rate was 79 % and 75 %, respectively, there was no significant different between two groups( P >0.05), but group A had less adverse reactions. CONCLUSION: Citalopram shows the similar effects to amitriptyline on treatment of depression. The former effects quicker than the later and has less adverse reactions.

目的 :比较西酞普兰和阿米替林治疗抑郁症的疗效和不良反应 ,方法 :抑郁症病人 88例 ,采用西酞普兰 2 2mg±s 6mg( 2 0~ 4 0mg·d 1) ,po ,疗程为 6wk。另用阿米替林治疗同类病人 87例 ,剂量为 10 0mg± 10mg( 50~ 150mg·d 1) po ,疗程为6wk。在治疗前及治疗后 1,2 ,4 ,6wk末予MAMD ,CGI ,TESS量表评定临床疗效。结果 :西酞普兰显效率 79% ,阿米替林组显效率 75% (P >0 .0 5) ,西酞普兰组不良反应较阿米替林组少。结论 :西酞普兰与阿米替林治疗抑郁症疗效相当 ,前者较后者起效快 ,不良反应少。

Objective:To assess the efficacy and safety of citalopram in the treatment of depressive disorders.Methods:29 patients with depression were enrolled into the multicentre open trial. The patients received the flexible dose of citalopram in the course of 6 weeks treatment. The efficacy was assessed with Hamilton Depression Scale and the safety was assessed with Treatment Emergent Symptom Scale.Results:The average dose of citalopram was (29.3±12.2) mg·d -1 .The response rate was 72.4% (21/29) and the remission...

Objective:To assess the efficacy and safety of citalopram in the treatment of depressive disorders.Methods:29 patients with depression were enrolled into the multicentre open trial. The patients received the flexible dose of citalopram in the course of 6 weeks treatment. The efficacy was assessed with Hamilton Depression Scale and the safety was assessed with Treatment Emergent Symptom Scale.Results:The average dose of citalopram was (29.3±12.2) mg·d -1 .The response rate was 72.4% (21/29) and the remission rate was 51.7% (15/29). The response time was around 3~4 weeks. There were less adverse reactions in the treatment of depressive disordors.Dry mouth (13.8%), dizziness (10.3%) and constipation (10.3%) were the frequent adverse reactions.Conclusion:Citalopram is an effective and safe antidepressant in the treatment of depressive disordors.

目的 :观察西酞普兰治疗抑郁障碍的疗效和安全性。方法 :采用多中心开放试验 ,纳入 2 9例单相抑郁或双相障碍抑郁发作患者。西酞普兰非固定剂量治疗 6周。汉密尔顿抑郁量表 (HAMD)评定疗效 ,治疗时出现的症状量表 (TESS)评定安全性。结果 :西酞普兰平均剂量 (2 9.3± 12 .2 )mg·d-1,有效率为 72 .4 % (2 1/ 2 9) ,临床痊愈率为 5 1.7% (15 / 2 9) ,起效时间大约在 3~ 4周。不良反应少见且程度轻 ,常见不良反应为口干 (13.8% )、头昏(10 .3% )和便秘 (10 .3% )。结论 :西酞普兰治疗抑郁症安全有效。

 
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