Conclusions The expression of HSF1 which increases after chemotherapy or hyperthermia in MCF-7 cell line can accelerate the expression of HSP70 and P-glycoprotein.
(2) Treating liver cancer cell line SMMC-7721 in 43℃,60min+CDDP 1.0ug/ml, light microscope 、electron microscope,and MTT results indicated that the dosage can inhibit liver cancer cell line growth,and the inhibit degree of thermochemotherapy group is larger than hyperthermia group and chemotherapy group.
The antimicrobials such as quinolone were administered for 4 to 8 weeks,and the alpha blockade,anti-inflammatories,thermotherapy and prostatic massage were given to part of the patients.
Methods 296 patients(319 target volumes)were treated by stereotactic radiotherapy,which include liver cancer 70,lung cancer 113,renal cell carcinoma 6,retro pelviperitoneal lymphatic metastasis 36,bone tumor 26,pancretic cancer 23,liver bile duct cancer 16,ovarian carcinoma 6.These patients were divided into two groups random,196 patients were treated by stereotactic radiotherapy single,100 patients were treated by combined stereotactic radiotherapy with radiofrequency diathermy directly or after peritoneal or pectoral cavity chemotherapy drug perfusion.
Results:The level of IL 2? TNF in thermochemotherapy group was close to the normal group(P>0.01). There were differences of IL 2 level and TNF level with statistical significance between the thermochemotherapy group and hyperthermia group,chemotherapy group and also the untreatment group(P<0.01).
Medical measures to decrease brain edema should be taken, including elevation of the head of the bed and avoidance of hypo-osmolar solutions, hypercarbia, or hyperthermia.
The effect of thermochemotherapy(i.e.a water bath applied to the region of the tumor at 44℃ for 30 minutes and CDDP administeredi.p.at a dose of 3mg/kg) wasevaluated in nude mice loaded with human ovarian cancer xenograft.16 mude mices were divided into 4 groups i.e.hyperthermia,chemotherapy,thermochemotherapy and controlgroup.The results showed that the minimal value of TRW/CRW was 3.2% in hyperthermia group,4.5% in chemotherapy group.There was no significant difference between two groups(P<0.05).The minim...
Abstract The activity of superoxide dismucase(SOD) and the level of lipid peroxide(LPO) were measured in normal and implantend S180 BALB/C mice.The results showed that the activity of SOD and the level of LPO in the group of hyperthermo-chemotherapy was close to the normal group(P>0.05).Authors also found that there were statistical significanee between the hyperthermo-chemotherapy group and hyperthermia group or chemotherapy group,or none of treatment group(P<0.01).On the other hand authors found that ther...