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    The difference was significant between siRNA+ASO2 group and siRNA group (all P<0.05). No significant difference was observed between siRNA+ASO1 group and siRNA group, neither between blank control group and liposome group (all P>0.05).
    siRNA组与siRNA+ASO1组比较,细胞对ECM的粘附与侵袭力差异均无统计学意义,而siRNA+ASO2组细胞对ECM的粘附与侵袭力较siRNA组降低(P均<0.05)。
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    The expressions of VEGF and MVD in the treated group were lower than those of the control group,and the apoptosis index of the transplanted tumor in the treated group was higher than that in the control group(P<0.01).
    实验组移植瘤组织微血管密度及VEGF蛋白表达明显低于对照组(P均<0.01),实验组癌细胞凋亡指数高于对照组(P<0.01)。
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    There were significantly differences (P<0.05) in comparing liver cancer group, ovarian cancer group, stomach cancer group with nomal control group.
    肝癌、卵巢癌、肺癌CA125阳性检出率和均数与正常对照组比较差异均有统计学意义(P均<0.05)。
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    Patients in the laparoseopic colectomy group enjoyed faster GI function recovery (P<0.01),less need for postoperative analgesics and shorter hospital stay (P<0.01).
    术后肠功能恢复时间、术后镇痛时间、饮食恢复时间以及术后住院时间均优于开腹手术(t值分别为6.15、6.53、6.15、45.6,P均<0.01);
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    There was a significant difference between displasia group and gastric carcinoma group (P<0.05) , as well as between gastric carcinoma with and without lymph node metastases.
    肠化生组与中重度异型增生组、中重度异型增生组与无淋巴结转移胃癌组、无淋巴结转移胃癌组与有淋巴结转移胃癌组之间差异均有统计学意义(P均< 0.05)。
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    c) The 10-year survival rate in the group with overexpression of TIMP-1 and TIMP-2 was higher compared to the group with lower expression of TIMP-1 and TIMP-2. Conclusion: Both TIMP-1 and TIMP-2 can serve as markers for prognosis of breast cancer patients.
    3)TIMP-1、TIMP-2高表达组10年生存率均高于低表达组(P均<0.01)。 结论:TIMP-1、TIMP-2均可作为乳腺癌患者预后判断的指标。
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    RESULTS: The content of MDA and activities of XOD, anti-· OH,anti-O2 increased and activities of 5'NT decreased significatly in cells treated with H2O2 . Compared with non-synchronized cells, the content of MDA and activities of XOD, 5'NT, anti-· OH and anti-O2 increased markedly in synchronized S-phase cells and G2/M-phase cells .
    结果:经H2O2处理的各组MDA含量和XOD、抗. OH、抗O2.-活性显著高于对照组,其差异均具有统计学意义(P均<0.01),5'NT活性低于对照组(P<0.01)。
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    Results Six weeks after operation,the percentages of CD+4 cells in treatment group increased more significantly than those in 2 weeks after operation and 6 weeks after operation in control group.
    结果治疗组术后第6周CD+4T淋巴细胞计数和CD4+/CD8+比值明显高于术后第2周和对照组术后第6周(P均<0.05);
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    In contrast to the control, the apoptotic rates (47.1% and 15.7%) of SKOV3 were increased after treatment with Celecoxib (5×10-5 mol/L) and Aspirin(7×10-3 mol/L).
    5×10-5mol/LCelecoxib和7×10-3mol/LAspirin组癌细胞凋亡率分别为47.1%、15.7%,均高于对照组(4.8%,P均<0.05);
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    The expression of CK20mRNA in peripheral blood of gastric carcinoma group was 35.7%. The positive detection of CK20 mRNA in peripheral blood was significantly correlated with tumor histological types and TNM staging, but had no coincidence with tumor position and sex.
    胃癌组外周血中CK20mRNA的阳性表达率在不同肿瘤组织学类型、TNM分期之间差异有统计学意义(P<0.05),在不同肿瘤部位及患者性别之间差异无统计学意义(P均>0.05)。
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  p
In this paper, we prove the degenerations of Schubert varieties in a minusculeG/P, as well as the class of Kempf varieties in the flag varietySL(n)/B, to (normal) toric varieties.
      
Well known wonderfulG-varieties are those of rank zero, namely the generalized flag varietiesG/P, those of rank one, classified in [A], and certain complete symmetric varieties described in [DP] such as the famous space of complete conics.
      
In this paper we compute the cohomology with trivial coefficients for the Lie superalgebraspsl(n, n), p (n) andq(2n); we show that the cohomology ring ofq(2n+1) is of Krull dimension 1 and we calculate the ring forq(3) andq(5).
      
As a corollary we obtain af·g·p·d·f subgroup of SLn(?) (n ≧ 3.
      
More generally, we prove that if Γ is an irreducible arithmetic non-cocompact lattice in a higher rank group, then Γ containsf·g·p·d·f groups.
      
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Four imaging techniques, namely, hepatic angiography, B-mode ultrasonography, CT and nuclide image, were used in 269 cases with primary hepatic cancer (PHC) verified by both operation and pathology. It was found that the diagnostic accuracy among these fcur imaging techniques for clinical, subclinical and huge PHC (>5.0cm) was similar except small hepatic cancer (≤5.0cm). For minute hepatic cancer (≤2.0cm), hepatic angiography was significantly more accurate than the other three imaging methods (90.0%, 75.0%,...

Four imaging techniques, namely, hepatic angiography, B-mode ultrasonography, CT and nuclide image, were used in 269 cases with primary hepatic cancer (PHC) verified by both operation and pathology. It was found that the diagnostic accuracy among these fcur imaging techniques for clinical, subclinical and huge PHC (>5.0cm) was similar except small hepatic cancer (≤5.0cm). For minute hepatic cancer (≤2.0cm), hepatic angiography was significantly more accurate than the other three imaging methods (90.0%, 75.0%, 40.5% and 30.0% respectively, P<0.01)At present, ultrasonography is the first choice because of its noninvasion. Hepatic angiography should be performed early in highly suspected patients when they have low titer of AFP and other imaging techniques fail to reveal cancer image.

本文采用四种显像方法,对269例经手术验证和病理证实的原发性肝癌诊断作了比较。发现肝动脉造影、B超、CT和核素肝显像对临床肝癌、亚临床肝癌和直径>5.0cm的大肝癌的确诊率相仿;对≤5.0cm小肝癌的确诊率分别为86.8%、82.7%、74.3%和68.3%,而对≤2.0cm微小肝癌造影较其他三种显象方法确诊率(分别为90.0%、75.0%、40.0%30.0%)更高(P均<0.01)。四种显像方法各具有优缺点,B超为非侵入性手段,应作为肝癌定位的首选方法,而对哪些甲胎蛋白(AFP)低浓度阳性而其他方法又无法发现的早期肝癌,应及早作肝动脉造影。

A sequential observation for 27 days was performed on IL 2 production and LTTlevels of the spleen cells from the Lewis lung cancer-bearing mice. Our results showedthat IL 2 and LTT levels and the thymus coefficient linearly declined with the incre-asing tumor weight (r_1=-0.8431, r_2 =-0.8654, r_3=-0.9037; P_(1-3)<0.01)andthat the reduction of IL 2 activity and the thymus coefficient occurred at the time beforethe palpable tumor appeared. A preliminary test was done to determine IL2 inhibi-tor (IN H ) in the...

A sequential observation for 27 days was performed on IL 2 production and LTTlevels of the spleen cells from the Lewis lung cancer-bearing mice. Our results showedthat IL 2 and LTT levels and the thymus coefficient linearly declined with the incre-asing tumor weight (r_1=-0.8431, r_2 =-0.8654, r_3=-0.9037; P_(1-3)<0.01)andthat the reduction of IL 2 activity and the thymus coefficient occurred at the time beforethe palpable tumor appeared. A preliminary test was done to determine IL2 inhibi-tor (IN H ) in the supematant of Con A activating spleen cells in tumor- bearing miceand the IL2 INH activity in such supematant was higher than that in normal mice.These results showed that the lower IL2 activity in tumorbearing mice probably related tothe higher IL2 INH activity, the lower LTT level and thymus coefficient.

本文观察了Lewis肺癌荷瘤小鼠脾细胞IL_2和Con A转化水平的动态变化。结果表明,随着荷瘤量增加,IL_2、Con A转化水平和胸腺系数均呈线性下降趋势(r分别为-0.8431、-0.8654和-0.9037,P均小于0.01),且IL_2和胸腺系数的下降发生在解剖后局部出现可见瘤块之前(P值分别小于0.001和0.05)。此外,本文初步检测了荷Lewis肺癌14日小鼠脾细胞Con A活化后,于上清中出现的IL_2 INH活性。并对荷瘤小鼠脾细胞IL_2活性降低、较高水平的IL_2 INH活性的存在、较低的Con A转化水平和胸腺萎缩等因素之间的关系作了讨论,有待于进一步探讨。

We observed that aidiron (912), which extracted from earthworm, had a strong killing effects on mice ascitic hepatoma cells (H22) in vitro by biochemical synthesis of DNA mesured with the incorporation of 3H-TdR and morphological method of the tumor cells. Different methods had different degrees for killing the tumor cells, in Group A (912-HpD-Laser), the percentage of the tumor cells killed was 74.4; Group B (HpD-Laser) was 59.7; Group C(Laser) was 20.4; Group D (912) was 27.0 and Group E (H22) as a control...

We observed that aidiron (912), which extracted from earthworm, had a strong killing effects on mice ascitic hepatoma cells (H22) in vitro by biochemical synthesis of DNA mesured with the incorporation of 3H-TdR and morphological method of the tumor cells. Different methods had different degrees for killing the tumor cells, in Group A (912-HpD-Laser), the percentage of the tumor cells killed was 74.4; Group B (HpD-Laser) was 59.7; Group C(Laser) was 20.4; Group D (912) was 27.0 and Group E (H22) as a control (0%). The results indicate that killing effects of hematoporphyrin dervative-laser combining with (912) were greats trong, compared to Group B, C and D (P<0.0l). We also observed the killing effects of each groups mentioned above on H22 tumor cells by measuring the amounts of the Schiff bases. The more intensive the fluorescence and higher the amounts of the Schiff bases were, the more tumor cells were killed. The fluorescence intensity of Group A was 84.6; Group B was 41.6; Group C was 45.1; Group D was 61.1 and Group E was 35.2mm respectively, Group A was higher (P<0.01).Furthermore by the chemiluminescence (CL) analysis we also discovered that during the procedure of the killing tumor cells with laser-HpD-912 there was the generation of hydrogen peroxide. These results of the determination show that the killing effects of laser-HpD-912 on H22 tumor cells were closely related with the production of reactive oxygenic species and which induced lipid peroxidation.

用~3H脱氧胸腺嘧啶核苷(~3H-TdR)参入DNA合成的生化学方法和癌细胞形态学方法观察到,不同方法处理腹水型(H_(22))肝癌细胞,其杀伤率,A组(912-HpD-laser)为74.4%;B组(HpD-912)为59.7%;C组(laser)为20.4%;D组(912)为27.0%;E组为0%作为对照。A组与其它组相比,杀伤作用显著增强(P均<0.01)。又通过测定脂质过氧化代谢产物Schiff碱的量观察各组对癌细胞的杀伤作用。Schiff碱有荧光特性,荧光强度越大,Schiff碱含量越高,癌细胞死亡数越多,上述5组的荧光强度测定结果分别是84.6,41.6,45.1,61.1和35.2mm。A组显著高于其它各组(P均<0.01)。进一步用化学发光法证明,912-激光-血卟啉衍生物杀伤癌细胞过程中有过氧化氢产生。上述结果提示,912-激光-血卟啉衍生物杀伤癌细胞的作用与活性氧的生成及其介导的脂质过氧化有密切关系。

 
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