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痒疹患者
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  prurigo pigmentosa
     Vesiculous prurigo pigmentosa in a 13-year-old girl: Good response to isotretinoin
     使用异维A酸治疗1例13岁色素性水疱型痒疹患者疗效显著
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  “痒疹患者”译为未确定词的双语例句
     Evidence that thalidomide modifies the immune response of patients suffering fro m actinic prurigo
     反应停(沙利度胺)调节光化性痒疹患者免疫应答的证据
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     Methods:60 patients were divided into two groups.
     方法 :结节性痒疹患者分成两组 ,每组 3 0例 ;
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     Methods SABC immunohistochemical technique was used to examine the expression of CGRP and SP in lesional skin and uninvolved skin of 30 cases of prurigo nodularis and in skin of 15 normal controls.
     方法 采用免疫组化SABC法 ,检测 30例结节性痒疹患者的皮损、非皮损区以及 15例正常人皮肤中CGRP和SP的分布和表达。
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     P were analyzed retrospectively.
     P患者的资料。
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     We reported an AIDS patient with prurigo as a main presenting sign.
     作者报告1例以痒疹为主要表现的艾滋病患者
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     Evidence that thalidomide modifies the immune response of patients suffering fro m actinic prurigo
     反应停(沙利度胺)调节光化性痒疹患者免疫应答的证据
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     The Circulating Immune Complexes in Patients with Uveitis
     葡萄膜炎患者的循环免疫复合物
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Objective:To observe the efficacy of colchicine combined with low dosage prednisone in treatment of prurigo nodularis. Methods:60 patients were divided into two groups. The study group was prescribed with colchicines 0.5 mg tid combined with prednisone 15 mg qd for oral and eloson cream for external use. The control group was prescribed with predisone 15 mg qd for oral combined with eloson cream for external use. The course was 4 weeks in both groups. The skin lesion, relieve of pruritus and side effect were...

Objective:To observe the efficacy of colchicine combined with low dosage prednisone in treatment of prurigo nodularis. Methods:60 patients were divided into two groups. The study group was prescribed with colchicines 0.5 mg tid combined with prednisone 15 mg qd for oral and eloson cream for external use. The control group was prescribed with predisone 15 mg qd for oral combined with eloson cream for external use. The course was 4 weeks in both groups. The skin lesion, relieve of pruritus and side effect were followed up every week. The effect of treatment was recorded after the treatment. Results: Aggregate efficacy of the study group was obviously better than that of the control group (80% vs 53.3%, P<0.05). Average relieving time of pruritus was 6 days in study group and 9 days in control group (P<0.01). Average regression time of nodules was 14 days in study group and 20 days in control group (P<0.01).Conclusion:Colchicines combined with low dosage of prednisone is an ideal method with the characteristics of fast effect, high efficacy and safety in treatment of prurigo nodularis.

目的 :研究秋水仙碱联合小剂量强的松治疗结节性痒疹的疗效。方法 :结节性痒疹患者分成两组 ,每组 3 0例 ;治疗组患者服用秋水仙碱片 0 5mgtid ,强的松片 1 5mgqd,艾洛松霜外用 ;对照组患者服用强的松片 1 5mgqd,艾洛松霜外用 ;两组疗程均为 4周 ;每周随访记录每例患者皮损变化情况、瘙痒减轻情况及不良反应 ,疗程结束后记录疗效。结果 :治疗组总有效率为 80 % ,而对照组为 5 3 3 % (P <0 0 5 ) ;治疗组和对照组的瘙痒减轻平均时间为 6天和 9天 (P <0 0 1 ) ;两组结节开始消退平均时间为1 4天和 2 0天 (P <0 0 1 )。结论 :秋水仙碱联合小剂量强的松治疗结节性痒疹具有起效快、有效率高、使用安全等特点 ,是一种较理想的治疗结节性痒疹的方法

Objective To study the role of calcitonin-gene-related peptide (CGRP) and substance P (SP) in the pathogenesis of prurigo nodularis. Methods SABC immunohistochemical technique was used to examine the expression of CGRP and SP in lesional skin and uninvolved skin of 30 cases of prurigo nodularis and in skin of 15 normal controls. Results The strong expression of CGRP and SP was observed in the whole epidermis of lesional skin in 30 cases, with the expression surrounding cell membranes. The weak expression...

Objective To study the role of calcitonin-gene-related peptide (CGRP) and substance P (SP) in the pathogenesis of prurigo nodularis. Methods SABC immunohistochemical technique was used to examine the expression of CGRP and SP in lesional skin and uninvolved skin of 30 cases of prurigo nodularis and in skin of 15 normal controls. Results The strong expression of CGRP and SP was observed in the whole epidermis of lesional skin in 30 cases, with the expression surrounding cell membranes. The weak expression of CGRP and SP was observed in nonlesional and normal epidermis. CGRP and SP expression levels had significant differences in the lesional skin and in normal and uninvolved skin (P< 0.01). Conclusion These findings support the concept of neuropeptide involvement in the occurrence of prurigo nodularis, and suggest that CGRP and SP may contribute to the development of the disease by mediating immune action.

目的 探讨降钙素基因相关肽 (CGRP)、P物质 (SP)在结节性痒疹发病中的作用。方法 采用免疫组化SABC法 ,检测 30例结节性痒疹患者的皮损、非皮损区以及 15例正常人皮肤中CGRP和SP的分布和表达。结果 CGRP和SP在结节性痒疹皮损全层皮肤中均有表达 ,呈环胞膜着色 ;在正常表皮和非皮损区中有轻度表达 ;在结节性痒疹皮损区CGRP和SP表达 ,与正常对照及未受累皮肤比较有显著性差异 (P <0 .0 1)。结论 神经多肽与结节性痒疹的发病有关 ,其可能通过免疫介导促进疾病的形成发展

 
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