The total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C) and total anti-oxidative capacity(T-AOC) in serum,and malondialdehyde(MDA) content in liver were measured.
1. Expression of the Human HDL Receptor (CLA-1) in Insect Sf9 Cells, Establishment and Application Research of CLA-1 Agonist Screening Model 2. Isolation and Relative Activities Research of Compounds Derived from Microorganisms
The cholesterol ester transfer protein (CETP) promotes exchange and transfer of neutral lipids such as cholesterol ester (CE) and triacylglycerol (TG) between plasma lipoproteins with secondary decrease in HDL size and protein content.
胆固醇酯转运蛋白(Cholesterol ester transfer protein,CETP)在血浆中促进血浆脂蛋白间的脂质交换与转运。 CETP高表达的结果是使高密度脂蛋白的胆固醇酯量(HDL-C)下降,极低密度脂蛋白胆固醇酯及低密度脂蛋白胆固醇酯量(VLDL-C,LDL-C)上升,其变化趋势与动脉粥样硬化呈正相关关系,被认为是一个防治动脉粥样硬化的靶标;
In 1996, the scavenger receptor class B, type I (SR-B I) was reported as the first molecularly well-defined and functionally active cell-surface HDL receptor (HDL-R).
Triglyceride (TG), total cholesterol(TC), high density lipoprotein-cholesterol (HDL-C), apolipoproteins A_I, A_(II), B (apo A_I,apo A_(II), apoB) levels in fasting serum were measured before treatment, the first and thirdcycle on treatment, the first cycle on discontinuating treatment respectively, The presentdata show that TG, HDL-C, apo A_(II), apo B parameters were changed significantly duringtreatment.
The results showed that antipsycho-tics significantly enhanced serum triglycerides (TG) and cholesterol (TC) level of the patients, namely the former increment was 1.1 mmol/L which reached close to the basic level 1.2 mmol/L and the latter 0.7 mmol/L after receiving the above agents for 9 wk, but it had no significant, influence on the HDL-ch.
Troxe-rutin was injected im 100 mg (2 mL) to 30 rabbits qd x 4 wk; normal saline was injected im 2 mL to the other 30 rabbits qd x 4 wk as control. The results showed that troxerutin markedly increased the high density lipoproteincholesterol and markedly reduced the cholesterol, Apo-B and the atheromatous plaque on aorta as compared with saline.
The result showed that serumTC and TG levels of Group and Group were markedly lower than those of the patterngroup (p<0.001) in 17 week, and the HDL-ch/TC ratio of the two groups was much higherthan that of the patern group (p<0.001).
One-way ANOVA revealed differences in the erythrocyte suspension viscosity, total globulins, triglycerides, high density lipoprotein cholesterol (HDL Ch), plasma viscosity, and acid resistance of erythrocytes.
The statistically significant two-way interaction effects of ADH7 StyI and CYP2E1 DraI on diastolic blood pressure (P = 0.029) and on the serum high density lipoprotein level (P = 0.042) were also revealed.
Plasma triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and apoA-I concentrations were markedly increased in T0901317-treated groups.
Body mass index (BMI) and lipid profile including total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and triglyceride correlated with blood pressure.
In pcDNA3.1-Retn-treated mice, both free fatty acid (FFA) and high density lipoprotein (HDL) cholesterol levels were markedly lower than those of control, whereas HDL cholesterol and triglyceride (TG) levels did not differ between the two groups.
Mean serum high-density lipoprotein cholesterol (HDL-c) levels were decreased significantly from 1982-1983 to 1997-1999, with the changes from -13.2% to -38.6% in males and from -9.8% to -21.7% in females.
The ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDL-c) increased dramatically during this period because of a concurrent decline in the levels of HDL-c and the increase in the levels of TC.
We evaluated the efficacy of alternate-day dosing of atorvastatin in comparison with the standard one-daily dose on total cholesterol, low and High-density lipoprotein (LDL and HDL) and triglycerides.
CETP thus plays a potential pro-atherogenic role by moving CE from HDL into pro-atherogenic VLDL and LDL particles, thereby lowering atheroprotective HDL cholesterol.
Mean serum high-density lipoprotein cholesterol (HDL-c) levels were decreased significantly from 1982-1983 to 1997-1999, with the changes from -13.2% to -38.6% in males and from -9.8% to -21.7% in females.
The ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDL-c) increased dramatically during this period because of a concurrent decline in the levels of HDL-c and the increase in the levels of TC.
In these two groups, as compared to subjects who did no cold training (the control group), the ratio of low-density lipoproteins to high-density lipoproteins (the atherogenicity coefficient) was significantly lower.
An improved microanalytioal method for determination of serum high-density lipoprotein (HDL)-cholesterol is herein presented. 80 μl of serum in a small test tube was added to sodium phosphotungstate and Mg3+ mixed reagent. This solution was drawn up into a capillary tube, which was sealed and centrifuged at room temperature for 30 minutes for precipitation of both the serum low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL). Cholesterol was then determined in the supernatant by means of i...
The effect of the total alkaloid obtained from the root of Ervatamin hainanensis Tsiang on experimental atherosclerosis as well as serum, aorta and liver, lipid levels in rabbits were studied.Rabbits in which atherosclerosis had been produced by cholesterol feeding were fed cholesterol diet together with the total alkaloid at a dosage of 60mg/kg/day for 8 weeks and this was compared with the controt group Without feeding the total alkaloid The results showed that the total alkaloid coused marked decrease of...
Refering to Miller's method, we had designed a perfusion system for the isolated rat liver. It consists of three parts: (1) the constant temperature apparatus, (2) the gas-exchange system and (3) the perfusion apparatus made of plexiglass (polymethyl methacrylate). In the upper part of the perfusion apparatus are a coiled glass tube for heating, a portal vein cannula, a themometer and a double-layered case filled with constant temperature water; in the lower part are to be found a funnel, a plate supporting...