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冠心病危险率
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  chd risk
    The review showed that stroke recurrent risk was reduced by 28%, CHD risk decreased by 15% and total mortality risk reduced by 11% in BP lowering treatment group compared with placebo control group.
    结果显示 :降压治疗组较安慰剂对照组降低脑卒中再发危险率 2 8% ,降低冠心病危险率 15 % ,降低总死亡率 11% ;
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  chd risk
The continuous progress in this area of research is getting us closer to the development of genetic screening panels that will allow a more precise assessment of individual CHD risk and response to therapeutic interventions.
      
A reasonable approach to the dyslipidemic patient with high CHD risk is to tailor the intervention to the specific lipoprotein abnormality.
      
Therefore, obesity should be considered a predisposing CHD risk factor, and treatment with diet, exercise, and newer pharmacologic agents can help patients achieve and maintain desired weight-loss goals.
      
The results of large-scale clinical trials evaluating the effect of vitamin E supplementation on CHD risk do not support the concept that this agent is cardioprotective.
      
The purpose of this report is to review dietary intervention trials that support a direct relationship between diet, lipoproteins, and CHD risk.
      
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Objective To review randomized controlled trials of blood pressure (BP) lowering therapy on stroke prevention to provide evidence for clinical practice. Method We searched Medline (1966-2003.6) and the large-sample randomized controlled trials on BP lowering regimen in patients with stroke history were reviewed. Endpoints included the ocurrance of stroke, coronary heart disease and mortality. Results Three trials of PATS, PROGRESS and HOPE were analysed. The review showed that stroke recurrent risk was reduced...

Objective To review randomized controlled trials of blood pressure (BP) lowering therapy on stroke prevention to provide evidence for clinical practice. Method We searched Medline (1966-2003.6) and the large-sample randomized controlled trials on BP lowering regimen in patients with stroke history were reviewed. Endpoints included the ocurrance of stroke, coronary heart disease and mortality. Results Three trials of PATS, PROGRESS and HOPE were analysed. The review showed that stroke recurrent risk was reduced by 28%, CHD risk decreased by 15% and total mortality risk reduced by 11% in BP lowering treatment group compared with placebo control group. Stroke risk was reduced not only in hypertensive patients with previous cerebrovascular diseases but also in non-hypertensive patients. Conclusions BP lowering therapy is beneficial for the secondary prevention of stroke.

目的 综合分析与脑卒中有关的降压治疗大样本随机对照试验 ,为脑卒中二级预防提供临床证据。 方法 计算机检索Medline(196 6 2 0 0 3年 6月 ) ,对已公开发表的大样本随机对照降压治疗预防脑卒中再发的临床试验进行综合分析。分析指标为脑卒中事件、冠心病事件及总死亡率等。 结果 共纳入脑卒中后抗高血压治疗的随机对照试验 (PATS)、多中心培哚普利降压治疗脑卒中 /一过性脑缺血发作的随机对照临床试验 (PROGRESS)和心脏结局预防评估研究 (HOPE) 3个试验进行综合分析。结果显示 :降压治疗组较安慰剂对照组降低脑卒中再发危险率 2 8% ,降低冠心病危险率 15 % ,降低总死亡率 11% ;降压治疗不仅能降低脑血管病或心血管病高危者伴高血压的脑卒中再发危险 ,而且对未伴高血压者也能降低其脑卒中危险。 结论 降压治疗对脑卒中二级预防是有益的。

 
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