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精神分裂症     
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  schizophrenia
     Studies on the Genes Associated with Schizophrenia of Chromosome 6q23-26
     人类染色体6q23-26精神分裂症相关基因的定位研究
短句来源
     Microarray Analysis of Altered Gene Expression and the Study of Genetic Susceptibility to Tumor Suppressor APC, TXNIP in Schizophrenia
     精神分裂症易感基因芯片筛查及与抑癌基因APC、TXNIP易感性研究
短句来源
     Study of Personality Change in Schizophrenia
     精神分裂症人格改变的研究
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     The Association of DA2、DA3、DA4 Receptor Gene Polymorphology with Schizophrenia Also in Medical Jurisprudence and Human Genetics Studies
     多巴胺D2、D3和D4受体基因多态性与精神分裂症关联性及法医学和人类遗传学意义
短句来源
     In Vitro Functional Study of IHH Mutations Causing BDA1 & Association Studies with Schizophrenia
     A1型短指(趾)症致病基因IHH的体外功能研究及精神分裂症关联分析
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  schizophrenic
     The factor scores were all markedly higher in the schizophrenic patients with homicide behavior than in other insanity patients with homicide behavior(t=2.36 to 4.14,P< 0.05 to 0.01).
     精神分裂症凶杀患者各项因子分均高于其他精神病凶杀患者,差异有显著性(t=2.36~4.14,P<0.05~0.01);
短句来源
     The gene expression levels of IL-1β,TNF-α and tyrosine hydroxylase in peripheral blood mononuclear cell of schizophrenic
     精神分裂症IL-1β、TNF-α和酪氨酸羟化酶的基因表达水平
短句来源
     Results:The average sick rate of schizophrenics was 0.14‰ from 1989~1998.The yearly morbidity rate of schizophrenic were 5.61‰,5 67‰,5 77‰,5 79‰,6 19‰,6 22‰,6 42‰,6.33‰,6.53‰,6.51‰(average rate 6.10%).
     结果 :1989年~ 1998年精神分裂症年平均发病率为 0 14‰ ; 逐年患病率分别为 5 6 1‰、5 6 7‰、5 77‰、5 79‰、6 19‰、6 2 2‰、6 42‰、6 .33‰、6 .5 3‰、6 .5 1‰ ,年平均患病率 6 10‰ ;
短句来源
     The results indicated that MK-801 (0.3 mg/kg、 0.6 mg/kg and 1.5 mg/kg) and KET (25 mg/kg、 50 mg/kg and 100 mg/kg) acute administration could induce schizophrenic symptoms of mice and the middle and high dosage groups were more significant than the low dosage group.
     结果表明,MK-801(0.3 mg/kg、0.6 mg/kg、1.5 mg/kg,i.p.)和KET(25 mg/kg、50 mg/kg、100 mg/kg,i.p.)不同剂量单次给药均可不同程度地诱导小鼠产生精神分裂症样症状,其中以中、高剂量组表现更为明显。
短句来源
     (2)There were no significant differences in the distributions of the alleles and the genotypes of the DAT1 gene between the schizophrenic patients and the healthy controls( Z <1.96, P >0.05).
     (2 )精神分裂症和健康对照组在DAT1的等位基因、基因型的分布上无显著性差异 (Z值小于 1.96 ,P >0 .0 5 )。
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  schizophrenics
     Results:The average sick rate of schizophrenics was 0.14‰ from 1989~1998.The yearly morbidity rate of schizophrenic were 5.61‰,5 67‰,5 77‰,5 79‰,6 19‰,6 22‰,6 42‰,6.33‰,6.53‰,6.51‰(average rate 6.10%).
     结果 :1989年~ 1998年精神分裂症年平均发病率为 0 14‰ ; 逐年患病率分别为 5 6 1‰、5 6 7‰、5 77‰、5 79‰、6 19‰、6 2 2‰、6 42‰、6 .33‰、6 .5 3‰、6 .5 1‰ ,年平均患病率 6 10‰ ;
短句来源
     Objective The present study was to investigate whether a polymorphism in the T102C region of the serotonin 2A (5-HT2A) receptor gene was associated with schizophrenia in comorbid siblings and sporadic schizophrenics.
     目的 探讨慢性精神分裂症患者的受累同胞和散发性精神分裂症与5-羟色胺2A受体基因(5-HT2A)T102C多态性的关联。
短句来源
     To explore whether symptom improvement in the 2nd week predict the curative effect in the 4nd week for schizophrenics taking clozapine ,40 schizophrenics were treated with clozapine, at the end of the 2nd -4th weeks the dose was fixed on 309 ±83 mg/d,and at the baseline and the ends of 2nd and 4th weeks PANSS were rated respectively.
     为研究氯氮平的2周症状改善是否能预测4周疗效,给40例精神分裂症病人予氯氮平治疗,在治疗2~4周末,剂量固定为(309±83)mg/d,于基线,治疗2周和4周末分别评定阳性和阴性症状量表(PANSS)。
短句来源
     The gene frequency of the allele 264 bp of D6S296 was 0.1688 in chronic schizophrenics, and was 0.039 0 in healthy persons (χ 2=17 68, P <0.001).
     慢性精神分裂症组患者D6S2 96的 2 64bp等位基因频率为 0 .1 688,而健康人组为 0 .0 390 ,差异有非常显著意义 (χ2 =1 7.68,P<0 .0 0 1 ) ;
短句来源
     Sixty-one schizophrenics were randomized into two groups blindly for comparison,the pipotiazine group(M 25, F 6;age 40± s 9 a,dosage 110± 35 mg/4wk,im for 6mo)and haloperidol group(M24,F 6;age 38± 9 a,dosage 120±28 mg/4wk im for 6mo).
     精神分裂症病人61例随机双盲分为哌泊塞嗓组(男性25例,女性6例,年龄40±s9a,每4wkim1次,平均剂量11±35mg/4wk,共6次)和氟哌啶醇组(男性24例,女性6例,年龄38±9a,每4wkim1次,平均剂量120±28mg/4wk共6次)。
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  schizophrenic patients
     The factor scores were all markedly higher in the schizophrenic patients with homicide behavior than in other insanity patients with homicide behavior(t=2.36 to 4.14,P< 0.05 to 0.01).
     精神分裂症凶杀患者各项因子分均高于其他精神病凶杀患者,差异有显著性(t=2.36~4.14,P<0.05~0.01);
短句来源
     (2)There were no significant differences in the distributions of the alleles and the genotypes of the DAT1 gene between the schizophrenic patients and the healthy controls( Z <1.96, P >0.05).
     (2 )精神分裂症和健康对照组在DAT1的等位基因、基因型的分布上无显著性差异 (Z值小于 1.96 ,P >0 .0 5 )。
短句来源
     Method:173 schizophrenic patients diagnosed according to CCMD 2 R were randomly assigned to treatment with 2mg,3mg,4mg or 5mg of risperidone daily.
     方法 :将符合精神分裂症诊断标准的患者随机分为 4组 ,分别用每日 2mg、3mg、4mg及 5mg剂量的利培酮治疗 ,疗程 12周。
短句来源
     Results IQ of schizophrenic patients was significant difference with normal controls'( P <0.001、 P <0.01 or P < 0.05).
     结果各精神分裂症组的IQ与正常对照组比较差异有统计学意义(P<0.001、P<0.01或P<0.05);
短句来源
     Type A behavior and schizophrenia:A clinical analysis of 200 schizophrenic patients
     A型行为与精神分裂症(附200例临床分析)
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  schizophrenia
Alterations in components of glutamatergic system and glutamate metabolizing enzymes are considered with reference to mental disorders such as senile dementia of Alzheimer's type and schizophrenia.
      
The molecular pathways for mental development, common forms of autisms, schizophrenia, and affective disorders have yet to be elucidated.
      
MicroRNA in schizophrenia: Genetic and expression analysis of miR-130b (22q11)
      
MiR-130b expressed in the brain and potentially targeting MECP2 is located in the susceptibility locus for schizophrenia (22q11).
      
Genetic association analysis of 300 schizophrenia and 316 normal control individuals revealed no statistically significant association of any of the miR-130b allelic variants with schizophrenia.
      
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  schizophrenic
(3) No significant correlations were found among S2/S1 ratio, S1-S2, 100 (1-S2/S1) of sensory gating and PANSS (P >amp;gt; 0.05) in schizophrenic group.
      
We performed a comparative analysis of the expression of miR-130b in 24 brain neocortex samples from schizophrenic and normal individuals.
      
Features of Auditory P300 in Relatives of Schizophrenic Patients
      
The subjects were parents, siblings, and children of schizophrenic patients.
      
In clean-up workers, somatosensory disorders were significantly associated with hypochondriac and schizophrenic-like symptoms.
      
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  schizophrenics
P50 auditory sensory gating in first onset schizophrenics and normal healthy adults
      
The aim of this research was to investigate the variations of P50 auditory sensory gating (P50) in normal healthy adults and the first onset schizophrenics.
      
The first onset schizophrenics had sensory gating deficits, which could be quantified by P50.
      
The analysis revealed a wide spectrum of mental disorders in schizophrenics and their relatives but not in the control group.
      
The errors of discrimination between schizophrenics and control subjects (a low-risk group) and between the low-risk group and sibs (a high-risk group) ranged from 7 to 19%.
      
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  schizophrenic patients
Features of Auditory P300 in Relatives of Schizophrenic Patients
      
The subjects were parents, siblings, and children of schizophrenic patients.
      
Relationships between the P300 Parameters and the Width of the Lateral Ventricles of the Brain in Schizophrenic Patients and The
      
Hemispheric Asymmetry in Prosody Perception by Healthy Subjects and Schizophrenic Patients
      
The relative genomic content of ribosomal repeats (rDNA) was estimated for 75 individuals, including 33 healthy donors (HD) and 42 schizophrenic patients (SP).
      
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