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A psychoactive drugs utilization study was undertaken in 3hospitals of Beijing with their out-patient clinics of internal medicines.Using DDD (defined daily dose) for each class of drugs, an index (drugutilization index) was calculated as an indicator of usage. The resultsshowed: (1 ) The percentage of the psychoactive drug prescriptions in thetotal was 20. 16 %, most of them include one psychoactive drug; (2 ) Thepercentage of psychoactive drug prescriptions in neurology was much higherthan that in internal... A psychoactive drugs utilization study was undertaken in 3hospitals of Beijing with their out-patient clinics of internal medicines.Using DDD (defined daily dose) for each class of drugs, an index (drugutilization index) was calculated as an indicator of usage. The resultsshowed: (1 ) The percentage of the psychoactive drug prescriptions in thetotal was 20. 16 %, most of them include one psychoactive drug; (2 ) Thepercentage of psychoactive drug prescriptions in neurology was much higherthan that in internal medicine; (3 ) The higher consumption of psychoac-tive drugs were oryzanol, benzodiazepines, follows by bromide preparations;(4 ) Utilization of psychoactive drugs was affected by sex and age; (5 )The utilization index of drugs except oryzanol was less than 1; (6) Therewas maybe an underuse problem of some drugs in the 3 hospitals becausethe index of some psychoactive drugs was too less. 统计分析北京市三家综合性医院内科系统1987年6月门诊处方26090张。研究结果表明:(1)含精神药物的处方占总处方的20.16%,其中绝大多数处方只开一种精神药物;(2)神经科精神药物处方的比例明显高于内科,为其3倍多;(3)内科系统门诊消耗最多的是谷维素、苯二氮(艹卓)类,其次为含溴化物的健脑合剂。镇痛药在内科系统应用较少,麻醉性镇痛药极少用;4)精神药物利用与性别有关,多类药物女性比例高于男性;(5)精神药物利用与年龄组有关;(6)按照WHO建议的DDD为单位测量三家医院的精神药物利用,除谷维素的利用指数大于1以外,其它均小于1,提示药物滥用倾向不明显;(7)某些药物的利用指数很小,是否存在用药量不足的问题值得研究。 The method of using ABC-ELISA to measure anti-HBc in the serum of patients with hepatitis B was developed.The expeimental results indicated that the sensitivity of ABC-ELISA was five times higher than that of the coventional ELISA and the positive detection rate of anti-HBc by means of ABC-ELISA increased by 4242%, Repeated experiments showed good reproductivity.Substitute tests using various antigens and antibodies of HBV and inhibition test using purified anti-HBc indicated that ABC-ELISA featured good specificity.A... The method of using ABC-ELISA to measure anti-HBc in the serum of patients with hepatitis B was developed.The expeimental results indicated that the sensitivity of ABC-ELISA was five times higher than that of the coventional ELISA and the positive detection rate of anti-HBc by means of ABC-ELISA increased by 4242%, Repeated experiments showed good reproductivity.Substitute tests using various antigens and antibodies of HBV and inhibition test using purified anti-HBc indicated that ABC-ELISA featured good specificity.A comparison was made between ABC-ELISA kit for detecting anti-HBcand the three conventional ELISA kits.Results showed that the positive detection rate by using ABC-ELISA kit increased by 25.00%, 45.28% and 30.77% respectively, as compared with the one by using three conventional kits produced by the Shanghai Infectious Disease Hospital, Jing Hua Company and Ke Hua Company.Through clinical specimen tests by the three hospitals in Shanghai, ABC-ELISA test demonstrated that this method had the following featuresxapidi-ty, sensitivity, specificity and good stability.ABC-ELISA has provided a reliable new method for the detection of anti-HBc. 应用生物素抗生物素系统酶联免疫吸附试验建立了检测乙型病毒性肝炎患者血清中抗HBc的ABC-ELISA方法并与普通ELISA进行了比较,结果表明:本法敏感性较普通ELISA法高4倍,阳性检出率提高了42.42%,且具有较好的重复性。将乙肝不同抗原、抗体进行替代试验和用纯化抗HBc-IgG进行抑制试验,证明本法有较高的特异性。本法制备成试剂盒,与上海市传染病院,静华公司及科华公司生产的普通ELISA试剂盒进行比较,结果本试剂盒阳性检出率分别提高25.00%,45.28%和30.77%。经上海市三家医院临床试验表明,本法具有快速、敏感、特异及稳定等优点。从而,为抗HBc的检测提供了一种新方法。 Gestational trophoblastic diseases were diagnosed in 1987 from three main hospitals of Guangxi.There were 30 cases of hydatidiform mole,30 cases of malignent mole and 20 cases of choriocar- cinema,The etiology and epidemiology of these diseases were investigated.Control groups were selected from normal postpartum women of the about three hospitals,who were indoor patients during the period of investigation.The ratio between the patient group and the control group was 1:2.The results were as follows:22 relatively... Gestational trophoblastic diseases were diagnosed in 1987 from three main hospitals of Guangxi.There were 30 cases of hydatidiform mole,30 cases of malignent mole and 20 cases of choriocar- cinema,The etiology and epidemiology of these diseases were investigated.Control groups were selected from normal postpartum women of the about three hospitals,who were indoor patients during the period of investigation.The ratio between the patient group and the control group was 1:2.The results were as follows:22 relatively significant factors were selected by single factore logistic regresion analysis method.Then,the following more related factors(P<0.05 or<0.01)were chosen by multiple-factors analysis,These factors are age,history of taking hormonal pills in the early stages of pregnancy,age of marriage of their husbands,age of menarche,number of pregnancies and the number of days of discontin- ued sexual intercourse before admitled to the hospitals. 省级三家医院1987年住院确诊滋养性细胞疾病患者:良性葡萄胎30例,恶葡30例,绒癌20例,进行患者的病因和流行病学调查,对照组选自同期住院的正常产妇。病例组与对照组按1∶2配对.结果:单因素 Logisitic 回归模型分析方法,选出22个有相对意义的因子。多因素分析:年龄、孕早期使用激素史、丈夫初婚年龄、初潮年龄、怀孕次数、停房事天数等,有显著意义(P均<0.05或<0.01).
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