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细胞中介
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  cell mediated
     CMI (cell mediated immunity) was detected by ANAE-focal pattern (F) or CD4 lymphocyte subpopulation.
     依ANAE-点型(F)或CD4淋巴细胞亚群检测细胞中介免疫(CMI)。
短句来源
  cell-mediated
     Thymosin α_1 accelerates restoration of T cell-mediated neutralizing antibody response in immunocompromised hosts
     α_1胸腺肽加快免疫妥协的宿主体内T细胞中介的中和抗体产生的恢复
短句来源
     We proved that chemically synthesized thymosinα 1 restored the T cell-mediated antibody production following its supression in mice by 5-fluorouracil(5-Fu).
     证明了化学合成的α1 胸腺肽恢复由 5 - Fu诱发的免疫抑制中 T细胞中介的抗体产量。
短句来源
  model organisms and mammalian cells
     The discovery that siRNA can direct gene-specific silencing in both model organisms and mammalian cells through RNA interference has provided a valuable platform for dissecting the function of independent genes.
     双链小干扰RNA(siRNA)在多种类型细胞中介导特异性的基因沉默,这一现象的发现为深入研究单个基因的功能提供了重要的方法学基础,从而得到了广泛的应用.
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  “细胞中介”译为未确定词的双语例句
     LMO2 is an important molecule mediating the formation of transcription factor complex in normal hematopoietic cells.
     LMO2是细胞中介导转录因子复合物形成的重要接头分子。
短句来源
     The results showed that the effect of TENS on analgesia and CMI was similar to that of EA in patients;
     结果表明患者的TENS镇痛及细胞中介免疫的效应均与EA的效应相似。
短句来源
     The results indicated that the fusion protein GST DB could inhibit the function of DDR2 on cells, and DDR2 might mediate collagen II induced over expression of MMP 1 in these cells.
     以上结果提示 ,表达的融合蛋白GST DB具有抑制天然DDR2功能的作用 ; DDR2在滑膜细胞和NIH 3T3细胞中介导II型胶原刺激下的MMP 1的分泌。
短句来源
     DOUBLE-STRANDED RNA-MEDIATED GENE SILENCING IN CULTURED MOSQUITO C6/36 CELLS OF AEDES ALBOPICTUS
     外源性双链RNA在蚊虫细胞中介导的基因沉默(英文)
短句来源
     With the definitude of its mechanism and the solving of the experimental technology problems,RNA interference has become a powerful tool in functional genomics and gene therapy, especially in the fields of tumor-related genes and gene therapy.
     小干涉RNA(smallinterferingRNA,siRNA)在哺乳动物细胞中介导转录后基因沉默(post-transcriptionalgenesilen-cing,PTGS),因其具有高效性和序列特异性,已经成为功能基因组学研究的有力工具之一,尤其在肿瘤相关基因的研究和肿瘤基因治疗研究领域取得了突破性进展。
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      cell mediated
    Saponin based adjuvants have the ability to stimulate the cell mediated immune system as well as to enhance antibody production and have the advantage that only a low dose is needed for adjuvant activity.
          
    The processes underlying lesion development appear to be heterogeneous, in some cases being driven by immune-cell mediated gliotoxicity and in others by primary gliopathy.
          
    The role of T cell subpopulations in cell mediated immunity to facultative intracellular bacteria
          
    This brief review summarizes the experimental data which underly the classic concept of anti-bacterial cell mediated immunity and will integrate recent developments focusing on results obtained byin vivo studies in the model of rodent listeriosis.
          
    In this study we investigated whether T-cell mediated immune response vary among male colour morphs in the trimorphic (white, yellow and red) common wall lizard, Podarcis muralis.
          
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      cell-mediated
    The obtained myoblast cultures were used in the clinical tests of cell-mediated gene therapy of Duchenne's muscular dystrophy as well as in the bioassay for the effects of biologically active compounds.
          
    Its specific interaction with HLA-G, a non-classical MHC class I molecule, has been suggested to play an important role in regulating NK cell-mediated cytotoxicity.
          
    Proteomic analysis of human NK-92 cells after NK cell-mediated cytotoxicity against K562 cells
          
    To better understand the natural killer (NK) cell cytotoxicity mechanism at the proteome level, we comparatively analyzed the proteome of the human NK-92 cells which participate in NK cell-mediated cytotoxicity assay and that of control cells.
          
    The Role of Chorionic Gonagotropin in the Formation of the Cell-Mediated and Humoral Immune Response
          
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    Blood T lymphocyte subpopulations, Ig production by mononuclear cells

    本文对9例蕈样肉芽肿(MF)病人血淋巴细胞同时用FC受体法及单克隆抗体法检测其血内的T淋巴细胞亚类的表面标志,并在试管内检测用美洲商陆(PWM)刺激后其单个核细胞悬液免疫球蛋白的产生,以及淋巴细胞的自发性细胞中介性细胞毒作用(SCMC)。同时,用冰冻切片及间接免疫过氧化酶技术对5例MF皮损内的浸润细胞进行免疫学表现型鉴定。结果表明:MF患者血内TG细胞显著增多、TM细胞正常;Leu2a~+细胞正常,而Leu3a~+细胞显著减少;试管PWM刺激单个核细胞Ig合成以及SCMC活性下降。在皮损内主要是Leu4~+,OKT_(11)~+,Leu3a~+,Ia~+细胞符合,它们是激活的T辅助/诱导细胞。在3例MF皮损中有相当数量的OKT_6~+细胞,在真皮上部为树枝状,在真皮中下层为圆形,提示它们可能是郎格罕氏细胞、胸腺细胞或未成熟的T细胞。

    patients with pain syndrome underwent TENS (transcutaneous electrical nerve stimulation) or EA (electroacupuncture) at Hegu acupoint as therapy; 42 mice were divided into 6 groups: ①dolantin group,②rotundin (opiate herb) group, ③acute morphine withdrawal (AMW) group, ④MW+ EA group, ⑤MW-EA group, ⑥control group.Pain threshold was detected by potassium ionophoresis method. CMI (cell mediated immunity) was detected by ANAE-focal pattern (F) or CD4 lymphocyte subpopulation. Immunoreactivity of cAMP and cGMP was...

    patients with pain syndrome underwent TENS (transcutaneous electrical nerve stimulation) or EA (electroacupuncture) at Hegu acupoint as therapy; 42 mice were divided into 6 groups: ①dolantin group,②rotundin (opiate herb) group, ③acute morphine withdrawal (AMW) group, ④MW+ EA group, ⑤MW-EA group, ⑥control group.Pain threshold was detected by potassium ionophoresis method. CMI (cell mediated immunity) was detected by ANAE-focal pattern (F) or CD4 lymphocyte subpopulation. Immunoreactivity of cAMP and cGMP was demonstrated by immunoenzyme histochemistry. The results showed that the effect of TENS on analgesia and CMI was similar to that of EA in patients;in mice,the analgesic effects were morphine>dolantin> EA or rotundin; while the CMI effects were EA>rotundin>dolantin or morphine; the intestinal cAMP-IR was increased and cGMP-IR relatively decreased in AMW group, and EA could modulate the alteration of cAMP-IR and cGMP-IR toward normal level.

    38例具有疼痛症状的患者在合谷穴接受TENS(穿皮电神经刺激)或电针治疗。将42只小鼠分为6组:①度冷丁组,②颅痛定(阿片样中草药)组,③急性吗啡戒断(AMW)组,④吗啡戒断加电针(MW+EA)组,⑤MW无EA(MW-EA),⑥对照组。以钾离子透入法测痛阀。依ANAE-点型(F)或CD4淋巴细胞亚群检测细胞中介免疫(CMI)。以免疫酶组织化学显示cAMP及cGMP免疫反应性(IR)。结果表明患者的TENS镇痛及细胞中介免疫的效应均与EA的效应相似。小鼠的镇痛效应为吗啡>度冷丁>颅痛定>电针或颅痛定,而细胞中介免疫的效应为EA>颅痛定>度冷丁或吗啡。AMW组的小肠cAMP-IR增加而cGMP-IR相对减弱,EA能调控cAMP-IR及cGMP-IR趋向正常水平。

    A number of cell strains were infected directly by recombinant adenovirus of AdCMVgdnf at a multiplicity of infec tion of 20, and the immunocytochemistry method was employed to examine the abilities that the recombinant adenovirus of AdCMVgdnf we constructed mediates GDNF gene transfer and expression in these infected cells. The results showed that the recombinant adenovirus of AdCMVgdnf can mediate gene transfer and expression of GDNF in all of the examined cells with high efficiency. It is concluded that the...

    A number of cell strains were infected directly by recombinant adenovirus of AdCMVgdnf at a multiplicity of infec tion of 20, and the immunocytochemistry method was employed to examine the abilities that the recombinant adenovirus of AdCMVgdnf we constructed mediates GDNF gene transfer and expression in these infected cells. The results showed that the recombinant adenovirus of AdCMVgdnf can mediate gene transfer and expression of GDNF in all of the examined cells with high efficiency. It is concluded that the recombinant adenovirus of AdCMVgdnf might serve as an ideal viral vector system for gene transfer and gene therapy for Parkinson's disease.

    用作者等所构建的重组腺病毒AdCMVgdnf直接感染多种细胞系和大鼠中脑原代神经元细胞,多重感染复数为20PFU/ml。采用免疫组织化学染色方法检测GDNF表达,观察所构建的GDNF重组腺病毒在各种细胞中介导GDNF基因转移和基因表达的能力。结果表明在一系列神经细胞或非神经细胞中,GDNF重组腺病毒均可介导GDNF基因的高效转移和表达。提示GDNF重组腺病毒可作为帕金森氏病基因治疗的高效基因转移载体。

     
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