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治疗组     
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  treatment group 1
     There was a significant difference in IL-10 content between the treatment group 1 and control group 1 (P<0.05).
     脑组织IL-10治疗1组与模型对照1组差异显著(P<0.05)。
短句来源
     Result The contents of IL-6 and IL-10 were increased in the treatment group 1 than that in the control group 1 (P<0.05). The content of IL-6 in the treatment group 2 was increased than that in the control group 2 (P<0.05).
     结果治疗1组外周血IL-6、IL-10比模型对照1组升高(P<0.05),治疗2组IL-6较模型对照2组升高(P<0.05)。
短句来源
     Results The development quotient for treatment group 1 was (98±8);
     结果治疗2组发育商(98±8)>治疗1组发育商(103±5)>对照组(86±9),差异具有统计学意义(P<0·05或P<0·01)。
短句来源
     The 3-year survival rate of treatment group 1 was signif icantly higher than those of treatment group 2, and control group (71.1% vs. 50. 0%, and 45.6%, P < 0.05).
     治疗1组的3年生存率为71.1%,明显高于治疗2组(50.0%)和对照组(45.6%)(P<0.05)。
短句来源
     NF200+/Brdu+ and FITC-NF200 stained cells increased rapidly,there was difference between treatment group 2 and treatment group 1 or model group significantly(P<0.01,0.05).
     损伤后F200+/Brdu+细胞和异硫氰酸荧光素-神经微丝(FITC-NF)200标记明显增加,治疗2组与治疗1组、模型组差异有统计学意义(P<0.01或0.05)。
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  treated group 1
     ②Cholestyramine treated group 1:methimazole, cholestyramine and propranolol for 4 weeks;
     ②治疗1组用考来烯胺、甲巯咪唑、普萘洛尔4周;
短句来源
     Results: The total leukocyte increasing effective rate occurred in the treated group 1 was 75.00%, that in the treated group 2 was 88.89%, in the control group 1 was 54.55% and in the control group 2 was 58.33%.
     结果 :升白疗效总有效率治疗 1组为 75 0 0 % ,治疗 2组为 88 89% ; 对照 1组为 54 55% ,对照 2组为 58 33%。
短句来源
     ③ Nerve electrophysiological data changes: Month 2 and 3, SNCV, MNCV and EPA were significantly higher in methylcobalamin+ insulin treated group 1 than in insulin treated group 1 (P < 0.05);
     ③神经电生理指标变化病程2和3个月时,甲钴胺+胰岛素治疗1组感觉和运动神经传导速度及波幅明显高于胰岛素治疗1组同期(P<0.05);
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     The 28 cases in the treated group 1 received SHSBG and CT simultaneously.
     治疗 1组 ( 2 8例 )为化疗同时服用双黄升白冲剂 ;
短句来源
     Two weeks after diabetic model was established, the sciatic tissue IGF-1 mRNA contents were obviously higher in methylcobalamin+ insulin treated group 1 than that in insulin treated group 1 (P < 0.05), but not significantly different from that in NC group;
     . 糖尿病成模后2周时,坐骨神经甲钴胺+胰岛素治疗1组组织胰岛素样生长因子1m RNA含量显著高于胰岛素治疗1组(P<0.05),与正常对照组差异不明显;
短句来源
  treatment 1 group
     Patients in the control group were given clinical treatment while those in treatment 1 group were given San Qo, rehabilitation training and electroacupuncture,and those in treatment 2 group were given hyperbaric oxygen based on treatment lgroup.
     对照组给予常规治疗(对症、抗血小板聚集、脱水降颅压、神经营养剂、防治并发症等治疗),治疗1组在常规治疗基础上加三七总皂苷、康复训练及电针治疗,治疗2组在治疗1组的基础上加用高压氧治疗。 三七总皂苷0.4g/天,连用14天;
短句来源
     Metheds Sixty-one patients of acute myocardial infarction were randomly divided into three groups: simvastatin treatment 1 group (20 mg/d of simvastatin,n=21), simvastatin treatment 2 group (80 mg/d of simvastatin,n=23), regular teatment group(no lipid-lowering drugs, n=17).
     方法将61例急性心肌梗死患者随机分为他汀治疗1组(辛伐他汀20mg/d,n=21)、他汀治疗2组(辛伐他汀80mg/d,n=23)和常规治疗组(不服用任何调脂药物,n=17);
短句来源
     To investigate cognitive function involved factors. Methods:80 patients with acute cerebral infarction of internal carotid system(ICS) were randomly divided into three groups,treatment 1 group and treatment 2 group and control group.
     [方法]:从2004年4月~2005年2月,在昆医附一院神经内科住院的患者中选择符合入组标准的80例颈内动脉系统急性缺血性卒中患者,采用随机原则将患者分为对照组、治疗1组和治疗2组。
短句来源
     Methods: The rats were randomly divided into treatment 1 group (invigorating plus sedative prescription), tre atment 2 group(invigorating, sedative prescription plus rhubarb), trauma control group an d health c ontrol group. The animal models of fracture were established in the two treatmen t groups and trauma control group.
     方法 :36只 Wistar大鼠随机分为治疗 1组 (补益 +安神组方 )、治疗 2组 (补益 +安神 +大黄组方 )、模型对照组和正常对照组 ,两个治疗组及模型对照组制成骨折创伤模型。
短句来源
  treatment group ⅰ
     Methods: A total of 38 SD rats were divided into 4 groups: normal control group (group A, n=8), heart failure group (group B,n=10),cozaar treatment group Ⅰ(group C,n=10), and cozaar treatment group Ⅱ(group D, n=10).
     方法:将38只SD大鼠随机分为4组:正常对照组(A组,n=8),心力衰竭组(B组,n=10),心力衰竭科索亚治疗1组(C组,n=10),心力衰竭科索亚治疗2组(D组,n=10)。
短句来源
     HA and PIIIP of treatment group Ⅱ were significantly different to treatment group Ⅰ( P < 0. 05).
     治疗2组HA、PIIIP与治疗1组比较,差异均有显著性意义(P<0.05)。
短句来源
     Results The total efficacy rate was 90.0% in treatment group Ⅰ and 76.7% in treatment group Ⅱ; there was a significant difference (P<0.05).
     结果治疗1组总有效率为90.0%,治疗2组为76.7%,差异有统计学意义(P<0.05)。
短句来源
     METHODS After atherosclerosis model was successfully made, animals (Japanese big ear rabbits) were divided into 3 groups( placebo group, treatment group Ⅰ and treatment group Ⅱ).
     方法 将日本大耳白兔分成对照组和高脂组 ,待高脂组形成动脉粥样硬化模型后分为 3组 (安慰剂组、治疗 1组和治疗 2组 )。
短句来源
     The control group (30 cases) was treated by common liver protection therapy, treatment group Ⅰ (40 cases) by γ-interferon, treatment group Ⅱ by KF associated with γ- interferon.
     对照组30例,采用一般护肝治疗; 治疗1组40例,采用γ-干扰素治疗;
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      treatment group 1
    Postoperative pulmonary complications and mortality in these patients with either a combined preoperative treatment (group 1, n=11) or chemotherapy alone (group 2, n=9) are evaluated in the present paper.
          
    We classified patients into those showing a ≥5% increase in LV ejection fraction (LVEF) at 3 months compared with LVEF values before the treatment (group 1,n=7) and those showing a >amp;lt;5% increase in LVEF (group 11,n=6).
          
    Mortality: classical treatment (group 1: 0%), surgical therapy (groups 2-5: 50%).
          
    Thirty-six nephritic animals received no treatment (group 1), while 36 were treated with vitamin E (group 2).
          
    The postoperative hospital stay was significantly shorter (P=0.01) in the treatment group (1.7 days) compared to the control group (2.3 days).
          
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      treated group 1
    On the other hand, administration of avidin 4 h after administration of the B-liposomes dramatically reduced the blood level so that it was only 5% of that in the non-treated group 1 h later.
          
    Although anatomical outcomes were better in the operatively treated group (1.6?mm vs 2.9?mm displacement at end of follow-up, p=0.001), there was no difference in neurological recovery.
          
    Control groups in which the defects were not treated (group 1), treated with collagen only (group 2), or treated with collagen and nontransduced MSCs (group 3) showed little or no osseous healing.
          
    In the deferoxamine-treated group 1 dog was excluded for hypotension in the preischemic period.
          


    (1) White mice were exposed to 40 cercariae of Schistosoma japonicum on the abdomen for 3, 5, 10, 15 and 20 minutes. Five weeks later, mice were killed and searched for worms. The percentage of worms recovered in the 5-minute group was found to be low (33%), whereas the differences between those in the 10-minute (45%), 15-minute (51%) and 20-minute (54%) groups were non-significant. (2) Infected mice were treated with tartar emetic given by mouth for 2 weeks. After a holding period of 1, 2, 3 or 4 weeks, mice...

    (1) White mice were exposed to 40 cercariae of Schistosoma japonicum on the abdomen for 3, 5, 10, 15 and 20 minutes. Five weeks later, mice were killed and searched for worms. The percentage of worms recovered in the 5-minute group was found to be low (33%), whereas the differences between those in the 10-minute (45%), 15-minute (51%) and 20-minute (54%) groups were non-significant. (2) Infected mice were treated with tartar emetic given by mouth for 2 weeks. After a holding period of 1, 2, 3 or 4 weeks, mice were sacrificed. The differences between the number of worms remained in the 4 groups of mice were non-significant. Therefore, one week may be adopted as the holding period in the screening test for antimonials. (3) In the control group and in the treated group with tartar emetic 270 mg/kg/day, there was no significant difference between the number of worms remained in male and in female mice. But in the treated group with tartar emetic 170 mg/kg/day, the number of worms remained in female mice was less than that in male mice. Hence it is advisable to use equal number of both sexes of mice in experimental therapy. (4) After the treatment with tartar emetic, mice were divided into 2 grades according to the body weights. The number of worms remained in mice of the 2 grades revealed a significent difference only in the group with holding period of 3 weeks, but not in other groups.

    (一)小白鼠腹部皮肤感染40条日本血吸虫尾蚴,感染时间自3至20分钟不等,5周後解剖,检查成虫数,发现感染尾蚴5分钟的成虫发育率较低(33%),而感染10分钟(45%),15分钟(51%)及20分钟(54%)之差别不显著。 (二)病员经口服吐酒石治疗2周後停药1,2,3或4周解剖,发现余存虫数之差别并不显著。所以可用1周作为比较锑剂疗效试验的停药时间。 (三)对照组及吐酒石270毫克/千克/天剂量组内,雌雄鼠体内余存虫数相差不显著,但在吐酒石1700毫克/千克/天治疗组内,雌鼠体内的余存虫数少於雄鼠体内的虫数。所以实验治疗所用的小白鼠最好是雌雄各半。 (四)吐酒石治疗後大小两级体重鼠体内余存虫数,仅在停药3周组内有显著的差别:其他组内则未见显著差别。

    (1) In 12 apparently healthy monkeys, the average respiratory rate was 46/minute, heart rate 227/minute, systolic/diastolic pressures 155/123 mm Hg, rectal temperature 39.0℃, erythrocytes 5.3 millionscu mm, leukocytes 15700 cu mm, among which lymphocytes 50.8%, neutrophils 45.0%, monocytes 2.0%, eosinophils 1.6%, and basophils 0.6%. (2) Sb-11 (H_2O_3Sb SCH_2COONa) is a pentavalent antimonial salt of stibonic acid. Intravenous injections at the daily dosage of 10 mg/kg in monkeys for 3 or 6 weeks produced no...

    (1) In 12 apparently healthy monkeys, the average respiratory rate was 46/minute, heart rate 227/minute, systolic/diastolic pressures 155/123 mm Hg, rectal temperature 39.0℃, erythrocytes 5.3 millionscu mm, leukocytes 15700 cu mm, among which lymphocytes 50.8%, neutrophils 45.0%, monocytes 2.0%, eosinophils 1.6%, and basophils 0.6%. (2) Sb-11 (H_2O_3Sb SCH_2COONa) is a pentavalent antimonial salt of stibonic acid. Intravenous injections at the daily dosage of 10 mg/kg in monkeys for 3 or 6 weeks produced no cough, nausea, vomiting, anorexia or other reactions. Likewise, Sb-11 had no significant influence on the respiration, blood pressure, EXG, temperature, and the blood cell counts. (3) Five monkeys were each infected with 300 cercariae of Schistosoma japonicum. Beginning on the 43rd day after the infection, Sb-11 was given intravenously on 3 monkeys at the dosage of 10 mg/kg/day for 3 weeks. The remaining 2 monkeys served as control. After a holding period of another 4 weeks, the monkeys were autopsied. The numbers of the helminths remained in the 3 monkeys of the medicated group were 0, 1 and 13 respectively, with the schistosomes all degenerated, while those of the control group were 81 and 138 respectively. So the therapeutic effect of Sb-11 was vory remarkable. (4) The toxicity of Sb-11 was rather low. Drug tolerance to Sb-11 developed quickly in monkeys; which showed no toxic manifestations after a course as long as 6 weeks. Hence Sb-11 is recommended to be tried clinically on those patients who cannot receive intensive treatment of tartar emetic.

    (一) 12只正常猴子平均呼吸頻率为46次/分,心跳为227次/分,收縮壓/舒張壓为155/12s毫米汞柱,體溫为39.0℃。平均紅血球5.3百萬/立方毫米,白血球15.7千/立方毫米,其中淋巴球50.8%,嗜中性45.0%,單核球2.0%,嗜酸性1.6%及嗜鹼性0.6%。 (二) Sb-11(H_2O_3Sb-SCH_2COONa)是5價之(月弟)酸鹽。猴子靜脈每天10毫克/千克,共3週或6週,無咳嗽、噁心嘔吐及食量減少等毒性反應,且對呼吸,血壓、心電圖、體溫及血球數等也無顯著影響。 (三) 5猴各感染日本血吸蟲尾蚴300條,其中2猴不给藥作對照,3猴自感染後第43天開始治療,劑量10毫克/千克/天,療程3週,停藥4週後解剖。對照组2猴各餘存蟲81與138條;治療組8猴分別餘存蟲0,1與13條,蟲體萎縮,所以療效非常顯著。 (四) Sb-11毒性低,對猴子能產生耐藥性,療程延長至6週亦無毒性表現。所以我們建議,臨床上吐酒石短程療法禁忌的病人,可試用Sb-11。

    The effects of combined treatment of Sb-71 with some metal salts such as cupric sulfate, magnesium sulfate, zinc sulfate, cupric chloride, magnesium chloride and zinc chloride were investigated in mice bearing Ehrlich ascites carcinoma. It was found that simultaenous administrations of Sb-71 (15 mg/kg) and cupric sulfate (1.5-3 mg/kg) produced a marked potentiation of inhibition of the growth of the carcinoma, and prolonged significantly the survival time of the mice. The density and the total number of ascites...

    The effects of combined treatment of Sb-71 with some metal salts such as cupric sulfate, magnesium sulfate, zinc sulfate, cupric chloride, magnesium chloride and zinc chloride were investigated in mice bearing Ehrlich ascites carcinoma. It was found that simultaenous administrations of Sb-71 (15 mg/kg) and cupric sulfate (1.5-3 mg/kg) produced a marked potentiation of inhibition of the growth of the carcinoma, and prolonged significantly the survival time of the mice. The density and the total number of ascites carcinoma cells were considerably decreased than those in the group treated with Sb-71 alone. Cupric sulfate alone at dosages of 1.5-3 mg/kg/day had no therapeutic effect on Ehrlich ascites carcinoma. Magnesium sulfate, zinc sulfate, cupric chloride and magnesium chloride did not influence the carcinostatic activity of Sb-71, whereas zinc chloride showed some antagonistic action against the therapeutic effect of Sb-71.

    本文研究了sb-71与几种金属盐合并治疗小白鼠Ehrlich腹水癌的疗效,結果发現用硫酸銅3毫克/公斤、硫酸鋅20毫克/公斤、硫酸鎂30毫克/公斤、氯化鎂30毫克/公斤及氯化銅2.5毫克/公斤与sb-71 30毫克/公斤合并治疗小白鼠Ehrlich腹水癌时,疗效无明显变化,但硫酸銅与sb-71合并治疗組的动物一般情况較好,腹水出現較晚、腹水量亦少。用上述金属盐与sb-71 15毫克/公斤合并治疗时发現硫酸銅1.5,3毫克/公斤能显著地提高sb-71对小白鼠Ehrlich腹水癌的疗效,动物的生存时間較单用sb-71組延长,腹水量、瘤細胞浓度、瘤細胞总数亦显著減少.硫酸銅本身无治疗作用;亦不影响sb-71的毒性.在sb-71 30毫克/公斤治疗小自鼠Ehrlich腹水癌的同时投給氯化鋅3,6毫克/公斤,后者明显地拮抗Sb-7l的疗效,动物生存时間明显地短于单用sb-71組。

     
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