IN all 35 of thermal injures (at 1200 mA for 12 min)were caused in the 21 tumor nodules. Complete necrosis as assessed at B type US in 11 of 14 nodules (79%) (Diameter<3 cm) compare with at helical CT in 3 of 7(43%)(Diameter>3cm) was achieved.
⑤ The DcR3 expression in HCC was associated with to portal vein tumor embolus,capsular infiltration and the number of the tumor nodes(P<0.01),while it was not correlated with age,sex, cirrhosis,plasma AFP levels or the histological classification(P>0.05).
But only 35 tumor nodes were found by two-dimensional color Doppler ultrasonography(85.37%). There was a significant difference between the two examinations(P<0.05).
The aim of this study is to observe the effect of apoptin gene injection into tumor node of in nude mice inducing apoptosis of human osteosarcoma cell line S180. Recombinant plasmid containing apoptin gene was transiently injected into tumor nodes in vivo through mediation of liposome.
Of 9 cases of primary liver tumor, node average diameter reduced from 3.5 cm to 3.0cm, 22 cases of metastatic hepatocarcinoma, node average diameter deduced from 3.6cm to 2.9cm.
In both H901 and SW1116 solid tumor nodules was found by light microscopic study (IM), after IR, tumor cells gradually replaced by lymphocytes and fibroblasts, shrinked till only isolated cell groups, then totally disappeared.
At subsequent exploratory laparotomy, three separate tumor nodules exhibiting varying degrees of pigmentation and ranging from 2.2 to 3.3 cm maximum dimension were excised.
Histologically, the tumor nodules were consistent with local recurrence/metastasis of the patient's previously excised pigmented adrenocortical neoplasm.
The transfection of pCH503in vivo has the chemotaxis on immune cells and can inhibit the formation of tumor nodes, suggesting that plasmid pCH503 is potentially useful in combined treatment of tumor.
The number of tumor nodes is determined more accurately by CT than by angiography because tumors are detected in patients without neurological deficit.