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      转移人
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  metastatic human
     Methods: The highly metastatic human breast cancer cell lines MDA-MB-435s and MDA-MB-231 were used in this study.
     方法:以高转移人乳腺癌细胞株 MDA-MB-435s 和 MDA-MB-231为研究对象。
短句来源
     In this regard, nude mice model of human hepatocellular carcinoma (LTNM1、LTNM2、LTNM3、LTNM4 ), nude rat model of human hepatocellular carcinoma (LTNR1、LTNR2), nude mice model of highly metastatic human hepatocellular carcinoma (LCI-D20), and highly metastatic human hepatocellular carcinoma cell line MHCC97 have been established and extensively studied.
     复旦大学肝癌研究所曾经建立了人肝癌裸小鼠移植模型(LTNM1-LTNM4)、人肝癌裸大鼠移植模型(LTNR1、LTNR2),高转移人肝癌裸小鼠模型(LCI-D20)、转移性人肝癌细胞系(MHCC97),进行了大量的研究。
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     Objective To study the effect of two cAMP analogs,8-Cl-cAMP(with site-selective for PKAⅡ) and DBcAMP(non-site-selective) on growth and differentiation of highly metastatic human lung cancer cells PGCC.
     目的 研究 2种cAMP类似物 ,DBcAMP (无位点选择性 )和 8-Cl -cAMP (位点选择性 )对高转移人肺癌细胞系PGCC细胞生长及分化的调控作用。
短句来源
     Methods: Our study was conducted on a highly metastatic human breast cancer cell line MDA-MB-231. Taking benzyl-α-GalNAc(a glycosilation inhinbitor) and RPMI-1640 group as positive and negative control respectively.
     方法:以高转移人乳腺癌细胞株MDA-MB-231为研究对象,应用糖基化抑制剂苯甲基-α-N-乙酰半乳糖胺为去糖基化阳性对照,以RPMI-1640为阴性对照。
短句来源
     Methods: Micropipette aspiration technique was used to investigate quantitatively the adhesion force (Fa) and the relative adhesion stress (S1) between high metastatic human lung giant cell carcinoma (PG) cells or low metastatic lung adenocarcinoma (PAa) cells and human umbilical vein endothelial cells (HUVEC).
     方法:采用微管吸吮技术定量测定低转移人肺腺癌(PAa)细胞和高转移人肺巨细胞癌(PG)细胞与脐静脉血管内皮细胞的粘附力(Fa)及相对粘附应力(S_1);
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  metastasis human
     [Purpose]To explore the effects of retinoic acid(RA),glycyrrhizin(GL),18β-glycyrrhetinic acid(GA),the combination of RA and GL,and the combination of RA and GA on proliferation inhibition and anti-invasion in highly metastasis human lung can-cer cells(PGCL3).
     [目的]探讨全反式维甲酸(RA)与甘草酸(GL)和18β鄄甘草次酸(GA)对高转移人肺癌细胞(PGCL3)增殖抑制和抗侵袭的作用及其联合作用。
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  “转移人”译为未确定词的双语例句
     Correlation og motility relaued protein-1(MRP-1)/CD9 with malignant behavior of human highly metastatic breast cancer cell line MDA-MB-231 in vitro
     MRP-1/CD9与高转移人乳腺癌MDA-MB-231细胞恶性行为相关性的体外研究
短句来源
     RESULTS: DDB at non-cytotoxic concentrations (10, 50 and 100 μmol/L) obviously inhibited the adhesion of MHCC97-H cells to LN and FN.
     结果:DDB在对细胞无明显毒性的浓度下(10、50和100μmol/L),能够明显抑制高转移人肝癌细胞MHCC97-H与FN、LN的粘附;
短句来源
     Inhibitory Effect of MT1-MMP Antisense Nucleotide on Invasion of Human Highly Metastatic Ovarian Cancer Cell Line SW626
     MT1-MMP反义核酸抑制高转移人卵巢癌SW626细胞的侵袭效应
短句来源
     We also used flow cytometer observed the expression of the thrombocytic immune related antigen CD42a, TSP and CD9 on PG and PAa, and the alter of the expression of CD42a,TSP and CD9 when the two cell lines were incubated with different level Elemene.
     利用流式细胞仪检测的高转移人巨细胞肺癌细胞PG 和低转移人肺腺癌细胞PAa表达的血小板免疫相关抗原CD42a、TSP、CD9的表达情况及二种癌细胞与高、中、低浓度的榄香烯注射液共同孵育后CD42a、TSP、CD9的表达改变。
短句来源
     IDENTIFICATION OF EXPRESSION OF ACTIVATED ONCOGEN AND PHENOTYPE OF TUMOR ANTIGENS IN HIGH METASTATIC GASTRIC CANCER CELL LINE SY86B
     高转移人胃癌裸鼠移植细胞系SY86B癌基因活化表达和肿瘤抗原表型特征分析
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  metastatic human
The resulting plasmid was sequenced and then introduced into PG cells, a highly metastatic human lung cancer cell line, by lipofectAMINE method.
例句来源      
The gene expression profile of highly metastatic human ovarian cancer cell line by gene chip
例句来源      
Objective: To study the gene expression of high metastatic human ovarian carcinoma cell line (HO-8910PM) and to screen for novel metastasis- associated genes by cDNA microarray.
例句来源      
We examined the expression of Gal-4 in primary and metastatic human ileal carcinoid tumors as well as in carcinoid tumors of the stomach, lung, and rectum.
例句来源      
HT1080 (metastatic human fibrosarcoma) and WI38 VA13 (virus-transformed human fibroblasts) were grown on substrates of collagen, collagen/hyaluronic acid or chondroitin sulphate and reconstituted basement membrane (Matrigel).
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         The HPRT deficiency had been induced with MNNG (N-methyl-N'-nitro N-nitrosoguanidine) in CHO-k1 cells and the cell clones were selected in a culture medium containing 6-thio-guanine (6-TG) .Although the cells were cultured for over 15 generations, the phenotype of HPRT- was stable.By the calcium phosphate coprecipitation and the electropration methods, the HeLa S3 DNA was transfered into HPRT gene deficient CHO cells. The' results indicated that the HPRT deficiency in the recipient cells was partially corre...
            中国仓鼠卵巢细胞(CHO-K1)经N-甲基-N'-硝基-N-亚硝基胍(MNNG)诱变和6-巯基鸟嘌呤(6-TG)选择,得到稳定的次黄嘌呤磷酸核糖转移酶(HPRT)缺陷细胞株,酶活性仅为野生型的6.5%。用磷酸钙共沉淀法和电脉冲法向HPRT-细胞转移人宫颈癌细胞(HeLaS_3)基因组DNA,纠正了CHO细胞的HPRT缺陷。酶活性提高了6.9倍,达到野生型的45%。用Alu序列探针进行分子杂交,证实经过基因转移并连续传代15次以上的受体细胞中含人DNA序列。表明人的有关基因已稳定地整合到CHO细胞的染色体中。
文摘来源
         A highly metastatic giant cell carcinoma (PG) and a poorly metastatic adenocarcinoma (PAa) were orthotopically implanted into nude mice, and the take rates were 74% for PG and 56% for PAa. Invasive tumors located in hilar region or peripheral part of lung, or spread diffusely, which were quite similar to three macroscopic types of primary lung carcinomas and different from well-circumscribed masses of ectopically implanted tumors. It is interesting to point out that the metastatic incidence of PAa cells in ...
            将高转移人肺巨细胞癌和低转移人肺腺癌常位移植于裸鼠肺内,其移植成功率分别为74%和56%,肺内移植瘤仍保持人原发肿瘤的病理组织学形态,其肉眼类型可呈肺门肿块,周围结节和弥散浸润型,与人类原发肺癌亦相似,而与局限膨胀生长或较少浸润的裸鼠皮下移植瘤有明显区别。肺内常位移植瘤较广泛地浸润胸部脏器,特别应当指出的是低转移肺腺癌细胞肺内移植其淋巴结转移率可达56%,甚至高于该癌系在beige裸鼠体内的淋巴结转移率。说明常位移植有利于恶性肿瘤表达其浸润转移表型。常位移植之肿瘤生物学行为更接近人体内原发性肿瘤的生物学行为,将成为研究人类肿瘤特性和实验治疗的更为适宜的实验模型。研究裸鼠皮下移植瘤和常位移植瘤基因表达的差异亦将为肿瘤浸润转移分子生物学基础的揭示作出贡献
文摘来源
         re-treatment of metastatic human lung cancer cell subline (PGCL3) with all trans retinoic acid(RA)resulted in inhibition of cell growth in vitro and invasion through the reconstituted basement membrane. RA was also noticed to inhibit the experimental metastatic ability of PGCL 3. Data showed that 5/6,3/6 and 2/6 of the nude mice developed lung colonization in the control, the 5μmol/L and the 10 μmol/L RA treated PGCL3 cells respectively.Data from DNA-RNA dot blot hybridization further showed that the 10 μmo...
            用5μmol/L和10μmol/L全反式维甲酸(RA)处理克隆化高转移人肺癌细胞(PGCL3)5天后,细胞的体外生长速度、穿过Boyden小室人工基底膜胶的浸润能力都受到一定的抑制,其中尤以10μmol/LRA的作用明显。实验性转移显示,RA体外处理PGCL3细胞可在一定程度上降低其实验性转移的能力。此外通过DNA-RNA斑点杂交还发现PGCL3细胞经10μmol/LRA处理5天后,人组织金属蛋白酶抑制剂基因(Timp-1和Timp-2)表达有一定水平的增高,这有助于进一步阐明RA抑制肿瘤细胞浸润和转移的机理。
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