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组织学损伤
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  histological injury
     ③Histological injury by was more alleviated in HFOV group than in CMV group.
     ③组织学损伤HFOV组较CMV明显减轻(P<0.05)。
短句来源
     On the 19th day, macroscopical, histological injury scores of colonic mucosa and tissue myeloperoxidase (MPO) activity were evaluated, and the mitotic index in Na-butyrate group was compared with that in SASP group.
     在第 19日处死 ,评价大体、组织学损伤及髓过氧化物酶 ( MPO)活性 ,并比较丁酸钠和 SASP组的核分裂指数。
短句来源
     It was studyed that the characteristics of histological changes in rat′s heart and skeleton muscles in the exercise induced exhausion and fatigue reasons by means of observing rat′s blood lactic acid change and the histological injury degree of heart and skeleton muscles after the exhaustive treadmill running and swimming with the load.
     】通过对大鼠跑台运动和负重游泳致力竭性疲劳时血乳酸的测定及对心肌、骨骼肌组织学损伤程度的观察,研究糖酵解供能条件下不同运动致力竭性疲劳时,心肌、骨骼肌组织学变化特征及致疲劳原因。
短句来源
     The results showed that when fatigue,the histological injury degree in treadmill running group was relatively lighter than that of swimming group,and the concentration of lactic acid in the former group was lower than that of the latter (P>0.001).
     结果表明,力竭性疲劳时,与游泳组相比,跑台组大鼠心肌和骨骼肌的组织学损伤相对较少,且血乳酸浓度也低于游泳组(P<0.01)。
短句来源
     Results Diarrhea was apparently improved, weight gain was not apparently different, the scores of macroscopical and histological injury and MPO activity decreased in the SASP group and the Na-butyrate group, compared with the control (P<0.05). However, there was not obvious difference between the Na-butyrate group and SASP group (P>0.05).
     结果 用丁酸钠和 SASP治疗组与生理盐水组比较 ,腹泻明显好转 ,体重恢复无明显差异 ,大体及组织学损伤计分明显改善 ,MPO活性明显降低 ( P<0 .0 5 ) ,但丁酸钠和 SASP治疗组之间无明显差异 ( P>0 .0 5 )。
短句来源
  histologic damages
     Compared with Sham operation group , the serum levels of Cr and BUN and MDA content were significantly higher (P <0.05 respectively) and renal histologic damages showed more severe, but TAOC decreased (P <0.05) in I/R group;
     与假手术组比较,I/R组Cr,BUN,MDA升高(P<0.05),TAOC降低(P<0.05),组织学损伤严重。
短句来源
     (2)Compared with groupⅣ,the serum levels of Cr and BUN and MDA content were significantly higher and renal histologic damages showed more severe,but TAOC decreased dramatically in groupⅢ;
     与Ⅳ组比较,Ⅱ、Ⅲ组Cr、BUN、MDA升高,TAOC降低,组织学损伤严重(均P<0.05);
短句来源
  “组织学损伤”译为未确定词的双语例句
     Methods:Acute colitis was induced by the administration of 3%、5%、8% DSS in C57BL/6 mice, In control,mice drank distilled water. The colonic injury and inflammation were assessed by disease active index (DAI) and histological index (HI) to evaluate the model.
     方法:采用让C57BL/6小鼠自由饮用DSS溶液的方法建立急性UC模型,设正常组、3%组、5%组、8%组共4组,进行进行疾病活动评分(disease active index,DAI)和肠粘膜组织学损伤评分(histological index,HI )以评估组织损伤和炎症程度,从而确定建立急性UC模型的合适浓度及时间。
短句来源
     Compared with model group, the inflammatory symptoms and injuries of colonic mucosa were significantly alleviated in treat group (P<0.01), histological score and the expression of NF-κBp65、iNOS、TNF-αin colonic mucosa were downregulated evidently (P<0.01).
     与模型组相比,治疗组大鼠的症状和结肠黏膜组织学损伤显著改善(P<0.01),两治疗效果没有明显差别(P>0.05),NF-κBp65、iNOS、TNF-α在肠组织的表达均显著降低(P<0.01)。
短句来源
     Results Compared with DSS control group, the inflammatory symptoms and histological damages of colonic mucosa in OM treated group were significantly improved( P <0.02, P <0.05), the serum levels of TNF α, IL 6 and the expression of NF κB, ICAM 1 in colonic mucosa were significantly reduced( P <0.01, P <0.05, P <0.05, P <0.01).
     结果 与OM未处理组相比 ,OM处理组大鼠的症状和结肠黏膜组织学损伤显著改善 (P值均 <0 .0 5 ) ,TNF α ,IL 6 ,NF κB和ICAM 1显著降低 (P值均 <0 .0 5 )。
短句来源
     In the meanwhile,the pathological lesion size resulting from RFCA was merely 0.41±0.11cm.
     而在该能量下,RFCA所造成的组织学损伤范围仅为0.41±0.11cm。
短句来源
     But the histological lesion area induced by RFCA was merely 0.41±0.11cm.
     而在该能量下,其造成的组织学损伤范围仅为0.41±0.11cm。
短句来源
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  histological injury
Pioglitazone can attenuate insulin resistance and biochemical and histological injury in high fat-induced fatty liver in rats.
      
Ipsilateral testes from non-treated groups had much greater histological injury than treated groups (p>amp;gt;0.05).
      
Comparison with morphological alterations showed a close relationship between loss of MAP2 staining and histological injury.
      
Histological injury was not observed in any of the examined brains.
      
The total histological injury score was the highest in the colon.
      
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The results of many studies demonstrated that the chick has a specificrequirement for selenium for growth and maintenance of pancreas exocrine func-tion.The pancreas is the target organ of selenium deficiency in chicks,whileskeletal muscle,heart muscle,liver and other tissues are unaffected if vitaminE is adequate.Selenium deficiency in chicks fed adequate vitamin E results inpancreatic degeneration and fibrosis.Compared with selenium-supplementedchicks,selenium deficiency animals had lower plasma tocopherols,higher...

The results of many studies demonstrated that the chick has a specificrequirement for selenium for growth and maintenance of pancreas exocrine func-tion.The pancreas is the target organ of selenium deficiency in chicks,whileskeletal muscle,heart muscle,liver and other tissues are unaffected if vitaminE is adequate.Selenium deficiency in chicks fed adequate vitamin E results inpancreatic degeneration and fibrosis.Compared with selenium-supplementedchicks,selenium deficiency animals had lower plasma tocopherols,higher fecalneutral lipids,higher bile weigts,higher activities of plasma glutamic-oxa- loacetic transaminase,and lower activities of pancreatic lipase and trypsin.Itappeared therefore,that there was a decreased hydrolosis of fat due to pancreaticdegeneration and lack of lipase,which in turn led to the impairment of lipid-bilemicelle formation necessary for absorption of lipids and vitamin E.The additionof bile acid to the diet led to only partial correction of the impaired fat di-gestion and vitamin E absorption.Supplementation with free fatty acids andmonoolein increased vitamin E absorption and survival of chicks,but did notprevent pancreatic fibrosis.The biochemical studies showed a decrease in zymogen activity and increasein the activity of lysosomal enzymes cathepsin and acid phosphatase.Thatselenium was an integral part of the enzyme glutathione peroxidase (GSH-PX),it was demonstrated that this enzyme was related to the prevention ofexudative diathesis (ED) in the chicks.The levels of selenium in the diet wasshown to be highly correlated with the plasma GSH-PX activity,but Contorreported that GSH-PX was shown to be not correlated with pancreatic atrophy.Histochemical studies revealed that the invasion of macrophages accounted forthe observed increase in lysosomal enzymes.No evidence of lysosomal disrup-tion was obtained during the course of the pancreatic degeneration indi-cating that role of selenium in prevevention of pancreatic degeneration wasnot in the protection of lysosomal membranes of the acinar cells.The sequence of histological lesions began with vacuolization and hylinebody formation in the acinar.Subsequently,fibroblasts could be observed in in-creasing numbers in the interacinar spaces,while the acinar cytoplasm wasshrinking basally,thereby enlarging the central lumen of the acinus.Finally,theacini appeared,as rings of cells composed mainly of small,densestaning nucleiand were completely surrounded by fibrotic tissue.The islets are very conspi-cuous,but incretory function was not disordered.The β-islet cells are unaffec-ted by selenium deficiency.Athough hyaline body formation could be observed,the breathing function of the mitochondria was not impaired.Histological examination of the pancreases indicated that wheat and sele-nomethionine were the most effective-sources of selenium.Selenomethionine wasfour times as effective as either selenium or selenocystine with respect to pre-vention of pancreatic degeneration.Severe pancreatic atrophy is followed ED.The biological availability of selenium for prevention of ED in chicks has beenshown to be greater for feedstuffs of plant than for those of animal origin.Selenocystine was shown to be more available than selenomethionine,but not aseffective as sodium selenite.

大量的研究结果证实,硒对维持雏鸡生长和胰腺外分泌机能具有专一的作用。胰腺是雏鸡硒缺乏的靶器官,而骨骼肌、心肌、肝脏和其它组织在维生素E 充足时,不受缺硒的影响。硒缺乏的雏鸡,即使喂给足够的维生素 E,胰腺也发生变性和纤维化。与补硒鸡相比,硒缺乏鸡血清中生育酚较低,粪中的中性脂类和胆汁较多,血清谷草转氨酶活性升高,胰脂酶和胰蛋白酶活性较低。此结果归因于胰腺的变性和脂酶的缺乏,从而降低了脂肪的水解,破坏了脂类和维生素 E 吸收所必需的脂类——胆汁微胶粒的形成。在日粮中加入胆汁酸,仅仅部分地改善脂肪的消化和维生素 E 的吸收。补饲游离的脂肪酸和单油酸甘油脂,增加了鸡的维生素E 吸收和存活时间,但不能防止胰腺的纤维化。生物化学研究还表明,酶原活性降低,溶酶体酶中的组织蛋白酶和酸性磷酸酶活性升高。硒是谷胱甘肽过氧化物酶(GSH—Px)的重要组分,此酶与鸡的渗出性素质相关;而且日粮中的硒含量与血清中 GSH—Px 活性高度相关,但是,Contor 报道,GSH—Px 与胰腺萎缩没有相关性。组织化学的研究揭示了由于巨噬细胞的侵润,而导致溶酶体的酶增多。在变性的胰腺中未获得溶酶体破坏的证据,由此证明,硒防止胰腺纤维化的作用,...

大量的研究结果证实,硒对维持雏鸡生长和胰腺外分泌机能具有专一的作用。胰腺是雏鸡硒缺乏的靶器官,而骨骼肌、心肌、肝脏和其它组织在维生素E 充足时,不受缺硒的影响。硒缺乏的雏鸡,即使喂给足够的维生素 E,胰腺也发生变性和纤维化。与补硒鸡相比,硒缺乏鸡血清中生育酚较低,粪中的中性脂类和胆汁较多,血清谷草转氨酶活性升高,胰脂酶和胰蛋白酶活性较低。此结果归因于胰腺的变性和脂酶的缺乏,从而降低了脂肪的水解,破坏了脂类和维生素 E 吸收所必需的脂类——胆汁微胶粒的形成。在日粮中加入胆汁酸,仅仅部分地改善脂肪的消化和维生素 E 的吸收。补饲游离的脂肪酸和单油酸甘油脂,增加了鸡的维生素E 吸收和存活时间,但不能防止胰腺的纤维化。生物化学研究还表明,酶原活性降低,溶酶体酶中的组织蛋白酶和酸性磷酸酶活性升高。硒是谷胱甘肽过氧化物酶(GSH—Px)的重要组分,此酶与鸡的渗出性素质相关;而且日粮中的硒含量与血清中 GSH—Px 活性高度相关,但是,Contor 报道,GSH—Px 与胰腺萎缩没有相关性。组织化学的研究揭示了由于巨噬细胞的侵润,而导致溶酶体的酶增多。在变性的胰腺中未获得溶酶体破坏的证据,由此证明,硒防止胰腺纤维化的作用,不在于保护胰腺细胞中溶酶体的膜。胰腺变性的病理组织学损伤,开始是在胰腺细胞内形成空泡和透明体,胰腺泡成带现象消失。其次,在胰腺泡之间出现成纤维细胞,全部细胞质基本上都皱缩了,因而扩大了胰腺泡的中央腔。最后,胰腺泡呈现由小的浓染的核所组成的细胞轮,并完全被纤维组织包围。内分泌胰岛显得非常明显,但内分泌机能不紊乱,β-胰岛细胞也不受缺硒的影响。尽管组织学观察到透明体,但线粒体的呼吸机能未受影响。胰腺的组织学检查证明,大麦和硒蛋氨酸是最有效的硒源,就予防胰腺变性的效力而言,硒蛋氮酸是亚硒酸钠和硒代胱氨酸的四倍。严重的胰腺变性常常继发渗出性素质,在防止鸡的渗出性素质中,植物源性硒的生物学活性比动物源性高,硒代胱氨酸比蛋氨酸活性大,但不如亚硒酸钠有效。

Fresh bile of grass carps was perfused into rats,stomaches to cause multiple organ damages and failures.The mortality rate of intoxicated rats was high.The therapeutic effects of hemodilution on rats lethally intoxicated by grass carp bile were observed,fifty-three SD rats were divided into three groups:the intoxicated group (n=25),the hemodiluted group (n=21) and the normal control group(n=7).The results showed that the increases in Ⅱ,SGPT, BUN of hemodiluted group were smaller than those of the intoxicated...

Fresh bile of grass carps was perfused into rats,stomaches to cause multiple organ damages and failures.The mortality rate of intoxicated rats was high.The therapeutic effects of hemodilution on rats lethally intoxicated by grass carp bile were observed,fifty-three SD rats were divided into three groups:the intoxicated group (n=25),the hemodiluted group (n=21) and the normal control group(n=7).The results showed that the increases in Ⅱ,SGPT, BUN of hemodiluted group were smaller than those of the intoxicated group.The pathomorphological changes of the hemodiluted group were slighter than those of the intoxicated group.The mortalitl rate in intoxicated group was higher than that in hemodiluted group.This indicated that hemodilution may have a protective effect against the otherwise fatal intoxication produced by grass carp bile.

新鲜鲩鱼胆汁给动物灌胃可引起多器官损伤,严重者致多器官功能衰竭,死亡率高.本文观察血液稀释(HD)对致死性鲩鱼胆汁中毒的治疗作用.实验采用 SD 大鼠53只.随机分为中毒组(n=25),稀释治疗组(n=21),正常对照组(n=7).实验结果表明,稀释治疗组动物的谷丙转氨酶(SGPT),黄疽指数(Ⅱ).尿素氮(BUN),升高幅度低于中毒组,肺、肝、肾病理组织学损伤轻于中毒组,24小时内死亡率中毒组高于治疗组,提示 HD 对致死性鲩鱼胆汁中毒可能有保护作用.

he effect of putrescine on oleic acid-inducedRDS were studied in rat,it was found that preadminis-tration of putrescine to rat with RDS significantly im-proved its hypoxemia,pulmonary edema and histologicinjury;inhibited the leakage of protein from plasma;lowered increase of pulmonary lipid peroxidation prod-ucts(malondialdehde,MDA).The result suggeststhat putrescine could have significant potential for clin-ical treatment of acute pulmonary injury.

在静脉注射油酸复制的大鼠呼吸窘迫综合征模型上发现,腐胺(50mg·kg ̄(-1),100mg·kg ̄(-1))可明显缓解油酸造成的肺损伤,减轻肺水肿和组织学损伤,改善低氧血症,抑制细胞内蛋白和细胞内酶的漏出,阻止肺组织丙二醛的聚集。结果提示腐胺对于急性肺损伤可能具有一定的防治作用。

 
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