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门静脉高血压
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  相似匹配句对
     Brand New View of Hypertension
     高血压新说
短句来源
     The second was hypertension.
     其次为高血压
短句来源
     Results: Blood hypertension ?
     结果 :高血压、动脉粥样硬化和肝硬化门静脉高压症是本病的主要原因。
短句来源
     Portal Hypertension in the Elderly
     老年门静脉高压症
短句来源
     group E (infused endotoxin into portal vein);
     门静脉内毒素血症组(E);
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  portal hypertension
We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
      
Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension (26 years clinical obse
      
The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.
      
From 1979 to 2005, 274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes, which were then compared with those of the traditional surgery treatment.
      
Splenic auto transplantation and esophageal transection anastomosis are a safe, effective, and reasonable treatment strategy for portal hypertension with varicial bleeding.
      
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To investigate the pathological morphology alteration of the splanchnic vascular wall in portal hypertensive patients Methods Splenic arteries, veins and gastric coronary veins from portal hypertensive pati ents (n=50) were removed during esophagogastric devascularization with splenecto my and were observed under optic and electron microscopes The expression of iN OS in the splenic artery wall was analysed with immunohistochemistry Results The internal elastic membrane and medial elastic fibers of the...

To investigate the pathological morphology alteration of the splanchnic vascular wall in portal hypertensive patients Methods Splenic arteries, veins and gastric coronary veins from portal hypertensive pati ents (n=50) were removed during esophagogastric devascularization with splenecto my and were observed under optic and electron microscopes The expression of iN OS in the splenic artery wall was analysed with immunohistochemistry Results The internal elastic membrane and medial elastic fibers of the splenic artery wa ll were broken and degenerated Atrophy, apoptosis and phenotypic changes were seen in smooth muscle cells of splenic arteries Positive staining for iNOS was seen in the cytoplasm of smooth muscle cells and iNOS activity was elevated com pared with the non cirrhotic patients ( P <0 01) In the splenic and gastri c coronary veins of cirrhotic patients, we found proliferative intima, extensive thrombi adhering to the venous wall, mimicked arteriosclerosis plaques accompan ied with hypertrophy of smooth muscle cells, and thickened muscle fibers of vein s with increase in extracelluar matrix Conclusion Portal hypertension may be complicated by splanchnic arterial and venous vasculo pathy There may be an interactive relationship among portal hypertension, spla nchnic hyperdynamic disturbances and splanchnic vasculopathy in the pathogenesis of portal hypertension

目的 研究门静脉高压症患者内脏血管壁的病理形态学改变。方法  5 0例门静脉高压症患者在行脾切除和贲门周围血管离断术时 ,取脾动脉、静脉和胃冠状静脉 ,行光镜和电镜观察。免疫组化法分析脾动脉壁诱导型一氧化氮合成酶 (iNOS)的表达。结果 脾动脉的内弹力膜和中膜内弹力纤维断裂和变性。脾动脉平滑肌细胞可见萎缩、凋亡和表型改变。平滑肌细胞的胞浆内可见iNOS阳性表达。肝硬化患者可见内脏静脉内膜增生 ,静脉壁有广泛的附壁血栓 ,类粥样硬化斑块形成 ,平滑肌细胞肥大 ,静脉肌纤维明显增粗和增厚 ,管壁细胞外基质增加。结论 门静脉高压症可合并内脏动脉和静脉的血管病变 ,在门静脉高压症的发病机制中 ,门静脉高压、内脏高动力循环和内脏血管病变之间具有相互影响的关系。关键词 门静脉高血压  血管病变  病理学早期糖尿病视网膜病变的多焦视网膜电图及临床意义MultifocalelectroretinogramsintheearlystagesofdiabeticretinopathyChinMedJ 2 0 0 2 ;115 (4 ) :5 63 5 66卫生部眼科学实验室 ,中山大学中山眼科中心广州 5 10 ...

目的 研究门静脉高压症患者内脏血管壁的病理形态学改变。方法  5 0例门静脉高压症患者在行脾切除和贲门周围血管离断术时 ,取脾动脉、静脉和胃冠状静脉 ,行光镜和电镜观察。免疫组化法分析脾动脉壁诱导型一氧化氮合成酶 (iNOS)的表达。结果 脾动脉的内弹力膜和中膜内弹力纤维断裂和变性。脾动脉平滑肌细胞可见萎缩、凋亡和表型改变。平滑肌细胞的胞浆内可见iNOS阳性表达。肝硬化患者可见内脏静脉内膜增生 ,静脉壁有广泛的附壁血栓 ,类粥样硬化斑块形成 ,平滑肌细胞肥大 ,静脉肌纤维明显增粗和增厚 ,管壁细胞外基质增加。结论 门静脉高压症可合并内脏动脉和静脉的血管病变 ,在门静脉高压症的发病机制中 ,门静脉高压、内脏高动力循环和内脏血管病变之间具有相互影响的关系。关键词 门静脉高血压  血管病变  病理学早期糖尿病视网膜病变的多焦视网膜电图及临床意义MultifocalelectroretinogramsintheearlystagesofdiabeticretinopathyChinMedJ 2 0 0 2 ;115 (4 ) :5 63 5 66卫生部眼科学实验室 ,中山大学中山眼科中心广州 5 10 0 60  余敏忠 张 欣 钟兴武 于 强 江福钿 马娟妹 吴德正目的 研究早期糖尿病视网膜病变的多焦视网膜电图特征及其临床意义。方法 采用VERISⅣ视觉诱发反应

Objective To evaluate the effect of improved extensive esophagoagsdtric devascularization on upper GI bleeding due to portal hypertension and to discuss the theoretical base and completeness. Methods From March 1997 to January 2002,22 portal hypertensive patients were treated using improved extensive esopha-goagastric devascularization.All of them were of post hepatitis cirrhosis and with a medical history of upper GI bleeding .FPP was measured respectively during the operation and after lienectomy and disconnection.The...

Objective To evaluate the effect of improved extensive esophagoagsdtric devascularization on upper GI bleeding due to portal hypertension and to discuss the theoretical base and completeness. Methods From March 1997 to January 2002,22 portal hypertensive patients were treated using improved extensive esopha-goagastric devascularization.All of them were of post hepatitis cirrhosis and with a medical history of upper GI bleeding .FPP was measured respectively during the operation and after lienectomy and disconnection.The measured data is analyzed with F test.The data of groups is analyzed with q test. Results Before lienectomy,free portal vein pressure(FPP) was (36.45±0.90)cm H 2O;after lienectoney,FPP was (27.64±0.90)cm H 2O; after disconnection,FPP was (30.64±0.98)cm H 2O. Through F test there are a very significant differences of FPP between the data of all groups(P<0.01).Through q test there are very significant difference of FPP between pre-and post-ienectomy(P<0.01),between pre-lienectomy and post-disconction(P<0.01).There is a slightly increase of FPP between post-lienectomy and post-disconnection(P>0.05).The bleeding control rate of emergency and precaution operation was 100%.One case died of postope-ratively of hepaticrenal failure and respiratory failure.There was one case with portal thrombosis.Incidence was both 4.1%.The follow-up time was 3~48 months with 32months an average time.Recurrent bleeding rate was 0. Conclusions The method of operation is active and effective. The advantages are:①Completet and thorough portal-azygous disconnection;②Uncomplicated operation;③More reduced blood stream of portal vein than with traditional methods,and no significant difference of FPP between post-lienectomy and post-disconection;④Little operative trauma and with no damage to the integrality of esophagus and stomach.⑤Less recurrent bleeding rate and the satisfactory effect.

目的 总结改进的贲门周围血管离断术治疗门静脉高血压症并发上消化道大出血的疗效 ,并对本术式断流的理论基础、彻底性进行讨论。方法  1 997年 3月— 2 0 0 2年 1月行贲门周围血管离断加断根术 2 2例 ,全部为肝炎后肝硬化所致门脉高压症 ,都有上消化道出血病史 ;切脾前、切脾后和断流后分别测自由门静脉压 (FreePortalveinPressure,FPP) ,所测数据用F检验分析 ,两两比较用q检验。 结果 切脾前检测FPP为 (36 .45± 0 .90 )cmH2 O ;切脾后FPP为 (2 7.64± 0 .90 )cmH2 O ;断流后FPP为 (30 .64± 0 .98)cmH2 O。经F检验各组的FPP差异有高度显著性 (P <0 .0 1 ) ;经 q检验切脾前、后比较和切脾前与断流后比较FPP差异有高度显著性(P <0 .0 1 ) ;切脾后与断流后比较FPP轻度上升 (P >0 .0 5)。急诊和预防性手术止血率 1 0 0 % ,围手术期死亡、手术后 2个月出现门静脉血栓各 1例 ,发生率均为 4 .1 %。随访时间为 3~ 48个月 ,平均 32个月 ,出血复...

目的 总结改进的贲门周围血管离断术治疗门静脉高血压症并发上消化道大出血的疗效 ,并对本术式断流的理论基础、彻底性进行讨论。方法  1 997年 3月— 2 0 0 2年 1月行贲门周围血管离断加断根术 2 2例 ,全部为肝炎后肝硬化所致门脉高压症 ,都有上消化道出血病史 ;切脾前、切脾后和断流后分别测自由门静脉压 (FreePortalveinPressure,FPP) ,所测数据用F检验分析 ,两两比较用q检验。 结果 切脾前检测FPP为 (36 .45± 0 .90 )cmH2 O ;切脾后FPP为 (2 7.64± 0 .90 )cmH2 O ;断流后FPP为 (30 .64± 0 .98)cmH2 O。经F检验各组的FPP差异有高度显著性 (P <0 .0 1 ) ;经 q检验切脾前、后比较和切脾前与断流后比较FPP差异有高度显著性(P <0 .0 1 ) ;切脾后与断流后比较FPP轻度上升 (P >0 .0 5)。急诊和预防性手术止血率 1 0 0 % ,围手术期死亡、手术后 2个月出现门静脉血栓各 1例 ,发生率均为 4 .1 %。随访时间为 3~ 48个月 ,平均 32个月 ,出血复发率为 0。结论 改进的贲门周围血管离断术疗效满意 ,其优点 :①断流彻底 ;②手术操作简便易行 ;③比经典的离断术减流更多 ,切脾后与断流后FPP改变无显著差异 ;④手术创伤小 ,不破坏食管和胃的完整性 ;⑤手术后再出血率低 ,效果良好

 
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