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   肝细胞特异性 的翻译结果: 查询用时:0.033秒
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肝细胞特异性
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  hepatocyte-specific
     Conclusion Combined detection of cancer-specific MAGE-1 mRNA and hepatocyte-specific AFPmRNA by nested RT-PCR in the peripheral blood of patients with HCC 28 days after surgery may be useful for the prediction of metastatic recurrence.
     结论采用巢式RT PCR的方法联合检测肝细胞癌患者术后28d外周血中癌特异性的MAGE1mRNA和肝细胞特异性的AFPmRNA有助于预测肝细胞癌患者术后的转移复发。
短句来源
     We examined the expression of hepatocyte-specific AFP gene transcripts, and that of cancer-specific MAGE-1 gene transcripts in blood specimens obtained from patients with HCC and also from HCC-free controls. The purpose of this study was to assess the utility of the multiple marker RT-PCR assay for detecting hepatoma cells and investigated the influence of an alternation of AFPmRNA and MAGE-1mRNA perioperatively detected in peripheral blood in matters of recurrence.
     本研究在围手术期联合检测了肝细胞癌病人外周血中肝细胞特异性的AFPmRNA和癌特异性的黑色素瘤抗原-1(MAGE-1)mRNA,以评价多标志物联合检测微转移的可行性及AFPmRNA和MAGE-1mRNA在围手术期的变化与术后转移复发的关系。
短句来源
     HGF prompted the ESC to develop further into visceral endoderm and mesoderm (myocardium), but both of them only expressed a low level of hepatocyte-specific metabolic functions.
     HGF促进ESC向内脏内胚层和中胚层(心肌)分化,但两者仅能表达低水平的肝细胞特异性功能。
短句来源
     These cells expressed hepatocyte-specific genes (AFP, OV-6, CK18, etc.) , and possessed functions of ICG uptake, albumin production and ammonium metabolism.
     这些细胞表达幼稚或成熟肝细胞特异性的AFP、OV6、CK18等基因,并具有靛青绿摄取、排泌和分泌白蛋白、氨基代谢生成尿素等功能。
短句来源
     Hepatocyte-specific albumin could be detected in mature cells.
     细胞胞浆内肝细胞特异性标志物白蛋白呈阳性染色;
短句来源
  “肝细胞特异性”译为未确定词的双语例句
     Conclusion:FFE T 1WI out phase sequence is the best sequence for contrast medium MnDPDP enhancement scan with T 1WI sequence,TR 25ms,TE 6.9ms,the reverse angle 20°is the best imaging parameter.
     结论:FFE T1WI out phase序列为肝细胞特异性对比剂泰乐影T1WI成像的最优序列,TR 25 ms、TE 6.9 ms、翻转角20°为其最优成像参数。
短句来源
     AFP,ALB,α_1-antitrypsin(AAT) and TTR mRNA were assayed by RT-PCR.
     RT-PCR检测肝细胞特异性标志基因ALB、AFP、甲状腺素运载蛋白(TTR)、α1抗胰蛋白酶(AAT)的mRNA表达;
短句来源
     During the culture medium, the reverse transcriptase polymerase chain reaction (RT PCR), immunocytochemistry (ICC) and radioimmunoassay (RIA) were used to determine the expression of hepatic genes and proteins, such as α fetoprotein (AFP),albumin (ALB),glucose 6 phosphatase (G6P),tyrosineaminotransferase (TAT),cytokeratin 8 (CK8), cytokeratin 18 (CK18) and urea, to analyse the hepatic differentiation.
     利用反转录聚合酶链反应 (RT PCR)、免疫细胞化学 (ICC)和放射免疫法 (RIA)动态检测肝细胞特异性基因和蛋白AFP ,ALB ,G6P ,TAT ,CK8,CK18等在培养体系中的表达 ,并测定肝细胞的尿素合成功能 ,最后测定肝细胞分化率 .
短句来源
     Conclusion HMSCs were induced to differentiate into hepatocyte-like cells by HGF, FGF-4 separately or HGF + FGF-4 in combination, which express some hepatic markers such as AFP, ALB and CK18. The effect of HGF + FGF-4 is among the strongest.
     结论HGF、FGF-4、HGF+FGF-4均能诱导HMSCs分化为肝样细胞,分化的肝样细胞能分泌肝细胞特异性产物AFP、ALB、CK18等。 以HGF+FGF-4诱导HMSCs分化为肝样细胞的阳性率最高。
短句来源
     Conclusion HMSCs can be induced to differentiate into hepatocyte-like cells by HGF, FGF-4 and their combination at certain concentrations, and the hepatocyte-like cells can express some hepatic markers such as AFP, ALB, CK18, etc.
     结论HGF、FGF-4、HGF+FGF-4均能诱导HMSCs分化为肝样细胞,分化的肝样细胞能分泌肝细胞特异性产物AFP、ALB、CK18等。
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  相似匹配句对
     Two Kinds of Phosphatitylcholine-Specific Phospholipase C in Liver Cells
     肝细胞内两种磷脂酰胆碱特异性磷脂酶C的活性
短句来源
     Construction of Hepatocyte Specific Gene Therapy Vector and its Function of Delivering Gene into Cells
     肝细胞特异性基因治疗载体的构建及活性研究
短句来源
     Liver Cell Adenoma
     肝细胞腺瘤
短句来源
     The specificity was also 100%.
     特异性100%。
短句来源
     LET isn't as specific as people wished.
     LET缺乏特异性
短句来源
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  hepatocyte-specific
However, the unequivocal identification of hepatocytes in ESC differentiation strategies has been hampered by a lack of hepatocyte-specific markers.
      
Recent studies are beginning to address this issue with the identification of hepatocyte-specific genes and the production of hepatocytes from intermediate cell types like definitive endoderm.
      
Cells proliferated, retained hepatocyte-specific functions, such as urea production and cytochrome P450 activity, and expressed liver-specific genes to levels observed in non-cryopreserved hepatocytes.
      
The expression of hepatocyte-specific genes was generally lower at the beginning than at later time-points of culture of individual passages.
      
Interleukin-3 induces hepatocyte-specific metabolic activity in bone marrow-derived liver stem cells
      
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This paper reports a new method established in our laboratory, called a liver cell-SPA-rose (L-SPA-R)forming test which was used to determine liver specific antibodies in viral hepatitis B in the study group(73 cases) and the control group (20 cases). The results showed that the L—SPA—R forming rate is higher in severe hepatitis and chronic active hepatitis than in chronic persistent hepatis(P<0.001), and it is also higher in the acute stage of acute hepatitis than in the convalescent stage. When the L-SPA-R...

This paper reports a new method established in our laboratory, called a liver cell-SPA-rose (L-SPA-R)forming test which was used to determine liver specific antibodies in viral hepatitis B in the study group(73 cases) and the control group (20 cases). The results showed that the L—SPA—R forming rate is higher in severe hepatitis and chronic active hepatitis than in chronic persistent hepatis(P<0.001), and it is also higher in the acute stage of acute hepatitis than in the convalescent stage. When the L-SPA-R forming rate increases continuously, acute hepatitis may become chronic, indicating that autoimmunization reaction plays an important role in hepatitis B, especially in chronic active hepatitis. The experimental method and its mechanisms are described briefly.

本文报告我们建立的肝细胞—葡萄球菌A蛋白花结形成试验(L—SPA—R),检测各型乙肝患者血清中肝细胞特异性抗体73例的结果。表明重肝与慢活肝患者L—SPA—R形成率高于慢迁肝(P<0.001),急肝患者急性期显著高于恢(?)期(P<0.001),L—SPA—R持续升高可能慢性化。说明自身免疫反应在乙肝,特别是在慢活肝发病机理中起一定作用。

The apolipoprotein A-Ⅰis an im-portant plasma protein which plays an essen-tial role in transportation and metabolism oflipid,and its gene expression shows evidenttissue-specificity,species-specificity and de-velopmental stage-specificity.By the coopera-tion of the cis-acting elements,eg. the liver-specific-enhancer at the 5' upstream regionand the positive or negative transcriptionalfactors such as ARP-1,HNF-4,RXRα,theapo A-Ⅰ gene is regulated to express specifi-cally.

载脂蛋白(apolipoprotein,apo)A-Ⅰ是一种重要的血浆蛋白,其基因表达具有明显的组织特异性、种属特异性和发育阶段特异性,ApoA-Ⅰ基因5'调控区的肝细胞特异性增强子等顺式作用元件同ARP-Ⅰ、HNF-4、RXR_α等反式作用因子相作用,调控该基因的特异性表达.

A rat regenerating liver model was made, in which the survival rate was over 95%, the remained lobes regenerated normally after partial (2/3) hepatectomy (PH), and fit for the following study. By examining both the heat resistance and specificity of liver cells, it was reasonable to conclude that the active substance in the model was hepatic stimulatory substance (HSS). HSS both extracted from regenerating liver and translated from its mRNA was assayed for its biological activity by using 3 H thymidine....

A rat regenerating liver model was made, in which the survival rate was over 95%, the remained lobes regenerated normally after partial (2/3) hepatectomy (PH), and fit for the following study. By examining both the heat resistance and specificity of liver cells, it was reasonable to conclude that the active substance in the model was hepatic stimulatory substance (HSS). HSS both extracted from regenerating liver and translated from its mRNA was assayed for its biological activity by using 3 H thymidine. The level of both protein and mRNA of HSS was altered regularly after PH ,i.e., the former reached its peak at 72 hour after PH, but as to the later, the peak was at 24 hour after PH. These data provided experimental basis for the following molecular cloning study.

本实验先制备大鼠肝再生模型,在该模型中大鼠成活率达95%以上,肝再生情况良好,适合于进行下一步的研究。随后,通过耐热性和肝细胞特异性的检测,初步认为从该模型中所提取的活性成分即为肝再生刺激物(HSS)。用3H胸腺嘧啶核苷测定HSS及其mRNA体外翻译产物的生物活性,结果表明二者在肝再生过程中均存在动态变化,但前者在肝部分(2/3)切除后72h活性最高,后者则在24h达高峰。这一结果为后续的分子克隆工作奠定了基础。

 
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