Objective To investigate the direct effects of recombinant membrane type matrix metalloproteinase-1 (MT1-MMP) catalytic domain (RMC) on cultured human osteoblast cells (hOB). Methods The effect of RMC on activation of proMMP-2 was measured by gelatin zymograms analysis.
目的观察重组膜型基质金属蛋白酶-1分解区蛋白(Recombinant membrane-type matrix metalloproteinase-1,MT1-MMP,catalytic domain,RMC)对人成骨细胞(normal human osteoblast cells,hOB)凋亡的影响,探讨MT1-MMP分解区蛋白在骨代谢中的作用。
The membrane form of CD28 in T cells and the serum level of soluble CD28 from peripheral blood of elders(beyond age of 60) were analysed in order to clarify its significance in the changes of immune functions in elders.
The mechanism of intercalated clay layer water film type landslide is different from other general landslide, from analyzing the macroscopic failure characteristics of intercalated clay layer water film type landslide, author analyzed the main control factors of intercalated clay layer water film type landslide and provided the calculating formulae of the improved limit equilibrium slope stability analysis coefficient.
If the frequency response of magnetic susceptibility is in the relax type of domain wall resonance, we could make film type Salisbury screen, in which the thickness of the screen may be in the order of micrometer or even sub micrometer.
e. ,pre-S2 was found in cytoplasm of hepatocytes,epithelial cells of bile ducts,and hepatocellular carcinoma cells,etc,Four different patterns diffuse,inclusion,submembranous,and membranous type were demonstrated.
Simultaneously, CEA localized mainly in the cytoplasm or stroma in the cancerous tissue,but in normal gastric tissue or benign gastric lession,CEA distributed mainly in the margin of gland with gastric depression or membranous type.
It was shown that nonselective pores are not formed in membranes of erythrocytes, which may indicate a dependence of the channel-forming ability on the membrane type.
Their slopes depend on the membrane type and the doping ion in the test solution.
Analysis of natural (mitochondrial and erythrocyte) membranes established that ionophoric activities of mini-gramicidin and its covalent dimer depend essentially on the membrane type.
On-line extraction of metal ions using liquid-liquid segmentation and a membrane type phase separator for fluorescence detection
The chelating reagent 8-hydroxyquinoline dissolved in methylisobutyl ketone (MIBK) was used to extract the metals and a membrane type phase separator was effective at separating the phases and directing the organic stream to the detector.
Biomaterials were prepared in the membrane form by bulk polymerization or solvent casting.
We have immunoselected variants which fail to express the membrane form (mIgM-); the most frequently isolated phenotype is a complete loss of both membrane expression and synthesis of the μ heavy chain within the cells.
A cDNA encoding a new secretory form of mouse membrane cofactor protein (MCP, CD46) was identified additionally to the membrane form cDNA.
The analyses created a contig of 257,153?bp containing 55?VH, 6?D, 12?JH genes and the IGH constant region genes encoding the functional secreted and membrane forms of IgM and the membrane form of IgD.
Purpose: The recombinant human interleukin-1 receptor (rhu IL-1R) is a soluble truncated form of the type 1 full-length membrane-bound receptor that binds IL-1 with identical affinity to that of the membrane form.
As a result of microscopic observation, the morphology of retained austenite could be characterized by two types: a granular type in steel containing higher Si and a film type in steel having higher C.
In the case of the steel containing higher C with a tensile strength of 860 MPa and a total elongation of 38%, the film type retained austenite could be observed among the lath bainitic ferrites.
In this study, the effect of overlap length on durability of a film type adhesive, Structural Bonding Tape (SBT) 9244, which possesses pressure-sensitive and visco-elastic properties, was investigated.
Compared with PAH-ending films, the PDL-ending ones upregulated the ICAM-1 expression of the ECs after a prolonged exposition to TNF-α, rendering this film type less favorable in tissue engineering.
The results obtained indicated that the diffusion coefficient was strongly dependent both on the distance between the FF monolayers in the range 4 nm to 85 nm (corresponding to the FF thickness) and on the film type.
The shunt flow rate calculated by ideal equation F = 2πR2 × NL overestimated the actu al shunt flow rate in ventricular septal defect, especially in membranous type.
Dependent on these structural differences four types are described: a filamentous, a granular, a globular, and a membranous type.
a filamentous, a granular, a globular, and a membranous type.
The findings suggest that is a developmental sequence from the filamentous type via the granular and globular to the membranous type.
Studies made with the critical electrolyte Alcian blue technique suggested that whether the ossification process is of the endochondral or membranous type might be predetermined in the relatively undifferentiated callus.
Pelves were measured. The most reliable sign of approaching parturition was restlessness and solitude by leaving far from the herd. The expulsion period of the fetus was 26.8+12 (8—50)minutes and that of the afterbirth was 69±47(21—184)minutes in average. Except the ordinary fetal membranes, full-term fetus had another membrane close to the surface of the body which was derived from the surface of the skin. The placenta was of the diffused and epithelio-chorial type.
Seven cases of glomerulonephritis are reported,among which 4 presented asnephrotic syndrome.Renal biopsies were performed because of poor response to treat-ment or presence of some findings not compatible with the usual clinical picture.Thepathological diagnoses were:chronic progressive,minimal,membranous and membrano-proliferative glomerulonephritis.Therapeutic regimen was thus corrected with goodresults.It is suggested that the diagnosis of glomerulonephritis should be made onboth clinical and pathological...
Seven cases of glomerulonephritis are reported,among which 4 presented asnephrotic syndrome.Renal biopsies were performed because of poor response to treat-ment or presence of some findings not compatible with the usual clinical picture.Thepathological diagnoses were:chronic progressive,minimal,membranous and membrano-proliferative glomerulonephritis.Therapeutic regimen was thus corrected with goodresults.It is suggested that the diagnosis of glomerulonephritis should be made onboth clinical and pathological findings so as to improve the diagnostic accuracy andtherapeutic efficacy.
Limit state analysis of reinforced concrete filmy flat shells is so far very rarely concerned. Based on the analysis and practical tests, failure patterns of this kind of shells are presented in this paper. It is found that the calculations by limit equilibrium principles agree with test results, thereby leading to a more rational and also more simplified way of calculation in design.